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Items: 1 to 20 of 56

1.
Grainyhead-like 2 interacts with noggin to regulate tissue fusion in mouse
Michael E. de Vries, Marina R. Carpinelli, Jarrad N. Fuller, Yindi Sutton, Darren D. Partridge, Alana Auden, Peter J. Anderson, Stephen M. Jane, Sebastian Dworkin
Development. 2024 Mar 1; 151(5): dev202420. Published online 2024 Feb 28. doi: 10.1242/dev.202420
PMCID:
PMC10946436
AbstractArticle
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The surface ectoderm exhibits spatially heterogenous tension that correlates with YAP localisation during spinal neural tube closure in mouse embryos
Abigail R. Marshall, Gabriel L. Galea, Andrew J. Copp, Nicholas D.E. Greene
Cells Dev. 2023 Jun; 174: None. doi: 10.1016/j.cdev.2023.203840
PMCID:
PMC10618430
AbstractArticlePDF–5.6M
4.
A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele
Zoe Crane-Smith, Sandra C P De Castro, Evanthia Nikolopoulou, Paul Wolujewicz, Damian Smedley, Yunping Lei, Emma Mather, Chloe Santos, Mark Hopkinson, Andrew A Pitsillides, Genomics England Research Consortium, Richard H Finnell, M Elisabeth Ross, Andrew J Copp, Nicholas D E Greene
Hum Mol Genet. 2023 Sep 1; 32(17): 2681–2692. Published online 2023 Jun 26. doi: 10.1093/hmg/ddad094
PMCID:
PMC10460492
AbstractArticlePDF–1.4M
5.
GRHL2 Regulation of Growth/Motility Balance in Luminal versus Basal Breast Cancer
Zi Wang, Bircan Coban, Chen-Yi Liao, Yao-Jun Chen, Qiuyu Liu, Erik H. J. Danen
Int J Mol Sci. 2023 Feb; 24(3): 2512. Published online 2023 Jan 28. doi: 10.3390/ijms24032512
PMCID:
PMC9916895
AbstractArticlePDF–2.9M
6.
Expression of Grainyhead-like 2 in the Process of Ductal Development of Mouse Mammary Gland
Shinya Matsuoka, Hiroyoshi Suzuki, Chieko Kato, Mai Kamikawa-Tokai, Akihiro Kamikawa, Yuko Okamatsu-Ogura, Kazuhiro Kimura
J Histochem Cytochem. 2021 Jun; 69(6): 373–388. Published online 2021 May 14. doi: 10.1369/00221554211013715
PMCID:
PMC8182637
AbstractArticlePDF–7.0M
7.
“Interrogating the Grainyhead-like 2 (Grhl2) genomic locus identifies an enhancer element that regulates palatogenesis in mouse”
Michael de Vries, Marina Carpinelli, Emilie Rutland, Aaron Hatzipantelis, Darren Partridge, Alana Auden, Peter J. Anderson, Bert De Groef, Han Wu, Marco Osterwalder, Axel Visel, Stephen, M. Jane, Sebastian Dworkin
Dev Biol. Author manuscript; available in PMC 2021 Mar 22.
Published in final edited form as: Dev Biol. 2020 Mar 15; 459(2): 194–203. Published online 2019 Nov 26. doi: 10.1016/j.ydbio.2019.11.015
PMCID:
PMC7984931
AbstractArticlePDF–2.1M
8.
GRHL2 induces liver fibrosis and intestinal mucosal barrier dysfunction in non‐alcoholic fatty liver disease via microRNA‐200 and the MAPK pathway
Ying Wang, Zishu Zeng, Lin Guan, Ran Ao
J Cell Mol Med. 2020 Jun; 24(11): 6107–6119. Published online 2020 Apr 23. doi: 10.1111/jcmm.15212
Correction in:
J Cell Mol Med. 2022 Jun; 26(11): 3311.
PMCID:
PMC7294114
AbstractArticlePDF–1.5M
9.
Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure
Marina R. Carpinelli, Michael E. de Vries, Alana Auden, Tariq Butt, Zihao Deng, Darren D. Partridge, Lee B. Miles, Smitha R. Georgy, Jody J. Haigh, Charbel Darido, Simone Brabletz, Thomas Brabletz, Marc P. Stemmler, Sebastian Dworkin, Stephen M. Jane
Dis Model Mech. 2020 Mar 1; 13(3): dmm042218. Published online 2020 Mar 25. doi: 10.1242/dmm.042218
PMCID:
PMC7104862
AbstractArticle
10.
The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
Kimberly J. Cocce, Jeff S. Jasper, Taylor K. Desautels, Logan Everett, Suzanne Wardell, Thomas Westerling, Robert Baldi, Tricia M. Wright, Kendall Tavares, Alex Yllanes, Yeeun Bae, Jeremy T. Blitzer, Craig Logsdon, Daniel P. Rakiec, David A. Ruddy, Tiancong Jiang, Gloria Broadwater, Terry Hyslop, Allison Hall, Muriel Laine, Linda Phung, Geoffrey L. Greene, Lesley-Ann Martin, Sunil Pancholi, Mitch Dowsett, Simone Detre, Jeffrey R. Marks, Gregory E. Crawford, Myles Brown, John D. Norris, Ching-yi Chang, Donald P. McDonnell
Cell Rep. Author manuscript; available in PMC 2019 Nov 22.
Published in final edited form as: Cell Rep. 2019 Oct 22; 29(4): 889–903.e10. doi: 10.1016/j.celrep.2019.09.032
PMCID:
PMC6874102
AbstractArticlePDF–2.4M
11.
Porphyromonas gingivalis Impairs Oral Epithelial Barrier through Targeting GRHL2
W. Chen, A. Alshaikh, S. Kim, J. Kim, C. Chun, S. Mehrazarin, J. Lee, R. Lux, R.H. Kim, K.H. Shin, N.H. Park, K. Walentin, K.M. Schmidt-Ott, M.K. Kang
J Dent Res. 2019 Sep; 98(10): 1150–1158. Published online 2019 Jul 24. doi: 10.1177/0022034519865184
PMCID:
PMC6704429
AbstractArticlePDF–1.3M
12.
Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2
Evanthia Nikolopoulou, Caroline S. Hirst, Gabriel Galea, Christina Venturini, Dale Moulding, Abigail R. Marshall, Ana Rolo, Sandra C. P. De Castro, Andrew J. Copp, Nicholas D. E. Greene
Nat Commun. 2019; 10: 2487. Published online 2019 Jun 6. doi: 10.1038/s41467-019-10164-6
PMCID:
PMC6554357
AbstractArticlePDF–9.8M
13.
A Grhl2-dependent gene network controls trophoblast branching morphogenesis
Katharina Walentin, Christian Hinze, Max Werth, Nadine Haase, Saaket Varma, Robert Morell, Annekatrin Aue, Elisabeth Pötschke, David Warburton, Andong Qiu, Jonathan Barasch, Bettina Purfürst, Christoph Dieterich, Elena Popova, Michael Bader, Ralf Dechend, Anne Cathrine Staff, Zeliha Yesim Yurtdas, Ergin Kilic, Kai M. Schmidt-Ott
Development. 2015 Mar 15; 142(6): 1125–1136. Published online 2015 Mar 10. doi: 10.1242/dev.113829
PMCID:
PMC6517833
AbstractArticle
14.
GRHL2-dependent enhancer switching maintains a pluripotent stem cell transcriptional subnetwork after exit from naïve pluripotency
Amy F. Chen, Arthur J. Liu, Raga Krishnakumar, Jake W. Freimer, Brian DeVeale, Robert Blelloch
Cell Stem Cell. Author manuscript; available in PMC 2019 Aug 2.
Published in final edited form as: Cell Stem Cell. 2018 Aug 2; 23(2): 226–238.e4. Published online 2018 Jul 12. doi: 10.1016/j.stem.2018.06.005
PMCID:
PMC6456389
AbstractArticlePDF–2.5M
15.
A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis
Matthew R. Jones, Salma Dilai, Arun Lingampally, Cho-Ming Chao, Soula Danopoulos, Gianni Carraro, Regina Mukhametshina, Jochen Wilhelm, Eveline Baumgart-Vogt, Denise Al Alam, Chengshui Chen, Parviz Minoo, Jin San Zhang, Saverio Bellusci
Front Genet. 2018; 9: 746. Published online 2019 Jan 23. doi: 10.3389/fgene.2018.00746
PMCID:
PMC6351499
AbstractArticlePDF–5.6M
16.
Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice
Sandra C P De Castro, Peter Gustavsson, Abigail R Marshall, William M Gordon, Gabriel Galea, Evanthia Nikolopoulou, Dawn Savery, Ana Rolo, Philip Stanier, Bogi Andersen, Andrew J Copp, Nicholas D E Greene
Hum Mol Genet. 2018 Dec 15; 27(24): 4218–4230. Published online 2018 Sep 4. doi: 10.1093/hmg/ddy313
PMCID:
PMC6276835
AbstractArticlePDF–25M
17.
Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways
Wei Chen, Kyung L. Kang, Abdullah Alshaikh, Saaket Varma, Yi-Ling Lin, Ki-Hyuk Shin, Reuben Kim, Cun-Yu Wang, No-Hee Park, Katharina Walentin, Kai M. Schmidt-Ott, Mo K. Kang
Oncogenesis. 2018 May; 7(5): 38. Published online 2018 May 8. doi: 10.1038/s41389-018-0047-5
PMCID:
PMC5938237
AbstractArticlePDF–2.2M
18.
GRHL2 Is Required for Collecting Duct Epithelial Barrier Function and Renal Osmoregulation
Christian Hinze, Janett Ruffert, Katharina Walentin, Nina Himmerkus, Elham Nikpey, Olav Tenstad, Helge Wiig, Kerim Mutig, Zeliha Yesim Yurtdas, Janet D. Klein, Jeff M. Sands, Federica Branchi, Michael Schumann, Sebastian Bachmann, Markus Bleich, Kai M. Schmidt-Ott
J Am Soc Nephrol. 2018 Mar; 29(3): 857–868. Published online 2017 Dec 13. doi: 10.1681/ASN.2017030353
PMCID:
PMC5827589
AbstractArticle
19.
Identification of a novel progenitor cell marker, Grainyhead-like 2 in the developing pituitary
Whitney Edwards, Leah B. Nantie, Lori T. Raetzman
Dev Dyn. Author manuscript; available in PMC 2017 Nov 1.
Published in final edited form as: Dev Dyn. 2016 Nov; 245(11): 1097–1106. Published online 2016 Sep 18. doi: 10.1002/dvdy.24439
PMCID:
PMC5065389
AbstractArticlePDF–1.5M
20.
A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure
Keith S. K. Fong, Robert B. Hufnagel, Vedbar S. Khadka, Michael J. Corley, Alika K. Maunakea, Ben Fogelgren, Zubair M. Ahmed, Scott Lozanoff
Dis Model Mech. 2016 May 1; 9(5): 585–596. doi: 10.1242/dmm.024109
PMCID:
PMC4892663
AbstractArticle

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