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Items: 1 to 20 of 25

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Mitochondrial protein MPV17 promotes β-cell apoptosis in diabetogenesis
Qiaoli Tang, Wanting Shi, Ming Liu, Liqin Tang, Wei Ren, Shaolin Shi
Clin Sci (Lond) 2023 Aug; 137(15): 1195–1208. Published online 2023 Aug 10. doi: 10.1042/CS20230164
PMCID:
PMC10415165
AbstractArticlePDF–8.8M
3.
Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition
Manti Guha, Satish Srinivasan, Maura M. Sheehan, Takashi Kijima, Gordon Ruthel, Kelly Whelan, Koji Tanaka, Andres Klein-Szanto, Prasanna M. Chandramouleeswaran, Hiroshi Nakagawa, Narayan G. Avadhani
Oncotarget. 2019 Oct 22; 10(58): 6245–6259. Published online 2019 Oct 22. doi: 10.18632/oncotarget.27264
PMCID:
PMC6817447
AbstractArticlePDF–3.8M
4.
Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages
Rajesh Angireddy, Hasan Raza Kazmi, Satish Srinivasan, Li Sun, Jameel Iqbal, Serge Y. Fuchs, Manti Guha, Takashi Kijima, Tony Yuen, Mone Zaidi, Narayan G. Avadhani
FASEB J. 2019 Aug; 33(8): 9167–9181. Published online 2019 May 7. doi: 10.1096/fj.201900010RR
PMCID:
PMC6662975
AbstractArticle
5.
hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction
Manti Guha, Satish Srinivasan, F. Bradley Johnson, Gordon Ruthel, Kip Guja, Miguel Garcia-Diaz, Brett A. Kaufman, M. Rebecca Glineburg, JiKang Fang, Hiroshi Nakagawa, Jeelan Basha, Tapas Kundu, Narayan G. Avadhani
PLoS One. 2018; 13(11): e0206897. Published online 2018 Nov 14. doi: 10.1371/journal.pone.0206897
PMCID:
PMC6241121
AbstractArticlePDF–2.6M
6.
Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model
Chloe F. Moss, Ilaria Dalla Rosa, Lilian E. Hunt, Takehiro Yasukawa, Robert Young, Aleck W. E. Jones, Kaalak Reddy, Radha Desai, Sam Virtue, Greg Elgar, Peter Voshol, Martin S. Taylor, Ian J. Holt, Martin A. M. Reijns, Antonella Spinazzola
Nucleic Acids Res. 2017 Dec 15; 45(22): 12808–12815. Published online 2017 Nov 2. doi: 10.1093/nar/gkx1009
PMCID:
PMC5728394
AbstractArticlePDF–2.1M
7.
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355
PMCID:
PMC5045200
AbstractArticlePDF–2.9M
8.
MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria
Ilaria Dalla Rosa, Yolanda Cámara, Romina Durigon, Chloe F. Moss, Sara Vidoni, Gokhan Akman, Lilian Hunt, Mark A. Johnson, Sarah Grocott, Liya Wang, David R. Thorburn, Michio Hirano, Joanna Poulton, Robert W. Taylor, Greg Elgar, Ramon Martí, Peter Voshol, Ian J. Holt, Antonella Spinazzola
PLoS Genet. 2016 Jan; 12(1): e1005779. Published online 2016 Jan 13. doi: 10.1371/journal.pgen.1005779
PMCID:
PMC4711891
AbstractArticlePDF–4.0M
9.
Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro
Gabriela Casalena, Stefanie Krick, Ilse Daehn, Liping Yu, Wenjun Ju, Shaolin Shi, Su-yi Tsai, Vivette D'Agati, Maja Lindenmeyer, Clemens D. Cohen, Detlef Schlondorff, Erwin P. Bottinger
Am J Physiol Renal Physiol. 2014 Jun 1; 306(11): F1372–F1380. Published online 2014 Mar 5. doi: 10.1152/ajprenal.00608.2013
PMCID:
PMC4042102
AbstractArticle
10.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
11.
Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice
Natalia Papeta, Zongyu Zheng, Eric A. Schon, Sonja Brosel, Mehmet M. Altintas, Samih H. Nasr, Jochen Reiser, Vivette D. D’Agati, Ali G. Gharavi
J Clin Invest. 2010 Nov 1; 120(11): 4055–4064. Published online 2010 Oct 18. doi: 10.1172/JCI43721
PMCID:
PMC2964992
AbstractArticlePDF–2.5M
12.
A Novel Transcriptional Repressor, Rhit, Is Involved in Heat-Inducible and Age-Dependent Expression of Mpv17-Like Protein, a Participant in Reactive Oxygen Species Metabolism
Reiko Iida, Misuzu Ueki, Toshihiro Yasuda
Mol Cell Biol. 2010 May; 30(10): 2306–2315. Published online 2010 Mar 15. doi: 10.1128/MCB.01025-09
PMCID:
PMC2863700
AbstractArticlePDF–984K
13.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
14.
Early-onset liver mtDNA depletion and late-onset proteinuric nephropathy in Mpv17 knockout mice
Carlo Viscomi, Antonella Spinazzola, Marco Maggioni, Erika Fernandez-Vizarra, Valeria Massa, Claudio Pagano, Roberto Vettor, Marina Mora, Massimo Zeviani
Hum Mol Genet. 2009 Jan 1; 18(1): 12–26. Published online 2008 Sep 24. doi: 10.1093/hmg/ddn309
PMCID:
PMC2644642
AbstractArticlePDF–6.0M
15.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
16.
Glomerular Overproduction of Oxygen Radicals in Mpv17 Gene-Inactivated Mice Causes Podocyte Foot Process Flattening and Proteinuria : A Model of Steroid-Resistant Nephrosis Sensitive to Radical Scavenger Therapy
Christoph J. Binder, Hans Weiher, Markus Exner, Dontscho Kerjaschki
Am J Pathol. 1999 Apr; 154(4): 1067–1075. doi: 10.1016/S0002-9440(10)65359-X
PMCID:
PMC1866567
AbstractArticlePDF–1.3M
17.
Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo
Alexei V. Evsikov, Joel H. Graber, J. Michael Brockman, Aleš Hampl, Andrea E. Holbrook, Priyam Singh, John J. Eppig, Davor Solter, Barbara B. Knowles
Genes Dev. 2006 Oct 1; 20(19): 2713–2727. doi: 10.1101/gad.1471006
PMCID:
PMC1578697
AbstractArticlePDF–1.7M
18.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
19.
The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species.
R M Zwacka, A Reuter, E Pfaff, J Moll, K Gorgas, M Karasawa, H Weiher
EMBO J. 1994 Nov 1; 13(21): 5129–5134. doi: 10.1002/j.1460-2075.1994.tb06842.x
PMCID:
PMC395460
SummaryPage BrowsePDF–1.8M
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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