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Items: 1 to 20 of 46

1.
Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation
Lisheng Zhang, Jiao-Hui Wu, Pierre-Yves Jean-Charles, Pavitra Murali, Wenli Zhang, Aeva Jazic, Suneet Kaur, Igor Nepliouev, Jonathan A. Stiber, Kamie Snow, Neil J. Freedman, Sudha K. Shenoy
J Biol Chem. 2023 Jul; 299(7): 104911. Published online 2023 Jun 11. doi: 10.1016/j.jbc.2023.104911
PMCID:
PMC10362797
AbstractArticlePDF–4.9M
2.
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice
Wenjie Zhang, Bowen Shi, Shirui Li, Zenglin Liu, Songhan Li, Shuohui Dong, Yugang Cheng, Jiankang Zhu, Guangyong Zhang, Mingwei Zhong
Front Endocrinol (Lausanne) 2022; 13: 1041027. Published online 2022 Dec 27. doi: 10.3389/fendo.2022.1041027
PMCID:
PMC9831654
AbstractArticlePDF–25M
3.
FBXL17/spastin axis as a novel therapeutic target of hereditary spastic paraplegia
Hyun Mi Kang, Dae Hun Kim, Mijin Kim, Yoohong Min, Bohyeon Jeong, Kyung Hee Noh, Da Yong Lee, Hyun-Soo Cho, Nam-Soon Kim, Cho-Rok Jung, Jung Hwa Lim
Cell Biosci. 2022; 12: 110. Published online 2022 Jul 22. doi: 10.1186/s13578-022-00851-1
PMCID:
PMC9308218
AbstractArticlePDF–2.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins
Jacob A. Culver, Malaiyalam Mariappan
J Cell Biol. 2021 May 3; 220(5): e202004086. Published online 2021 Apr 1. doi: 10.1083/jcb.202004086
PMCID:
PMC8020466
AbstractArticlePDF–5.0M
6.
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase
Hyo Jin Kim, Jongchan Kim
Int J Mol Sci. 2021 Feb; 22(4): 1936. Published online 2021 Feb 16. doi: 10.3390/ijms22041936
PMCID:
PMC7919836
AbstractArticlePDF–5.0M
7.
Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2
Wenyang Li, Minhong Shen, Yi-Zhou Jiang, Ruina Zhang, Hanqiu Zheng, Yong Wei, Zhi-Ming Shao, Yibin Kang
Genes Dev. 2020 Oct 1; 34(19-20): 1310–1315. doi: 10.1101/gad.339804.120
PMCID:
PMC7528704
AbstractArticlePDF–2.3M
8.
The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62
Jihoon Ha, Minbeom Kim, Dongyeob Seo, Jin Seok Park, Jaewon Lee, Jinjoo Lee, Seok Hee Park
Int J Mol Sci. 2020 May; 21(9): 3116. Published online 2020 Apr 28. doi: 10.3390/ijms21093116
PMCID:
PMC7247158
AbstractArticlePDF–3.3M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate
Christian M. Loch, James E. Strickler
Biochim Biophys Acta Mol Cell Res. 2012 Nov; 1823(11): 2069–2078. Published online 2012 May 21. doi: 10.1016/j.bbamcr.2012.05.006
PMCID:
PMC7113913
AbstractArticlePDF–1.5M
11.
USP37 is a SNAI1 deubiquitinase
Zhenna Xiao, Liang Chang, Jongchan Kim, Peijing Zhang, Qinglei Hang, Shannon Yap, Youming Guo, Zhicheng Zhou, Liyong Zeng, Xiaoyu Hu, Ashley Siverly, Yutong Sun, Li Ma
Am J Cancer Res. 2019; 9(12): 2749–2759. Published online 2019 Dec 1.
PMCID:
PMC6943346
AbstractArticlePDF–1.2M
12.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
13.
Structural and functional studies of USP20 ZnF‐UBP domain by NMR
Yuanyuan Yang, Yiluan Ding, Chen Zhou, Yi Wen, Naixia Zhang
Protein Sci. 2019 Sep; 28(9): 1606–1619. Published online 2019 Aug 9. doi: 10.1002/pro.3675
PMCID:
PMC6699088
AbstractArticlePDF–7.1M
14.
FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane
Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri
Structure. Author manuscript; available in PMC 2020 Jun 4.
Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022
PMCID:
PMC6551266
AbstractArticlePDF–3.4M
15.
The deubiquitinase ubiquitin–specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling
Samuel Mon-Wei Yu, Pierre-Yves Jean-Charles, Dennis M. Abraham, Suneet Kaur, Clarice Gareri, Lan Mao, Howard A. Rockman, Sudha K. Shenoy
J Biol Chem. 2019 Feb 15; 294(7): 2500–2518. Published online 2018 Dec 11. doi: 10.1074/jbc.RA118.004926
PMCID:
PMC6378982
AbstractArticlePDF–5.3M
16.
Ubiquitin-specific Protease 20 Inhibits Tumor Necrosis Factor-triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis
Pierre-Yves Jean-Charles, Jiao-Hui Wu, Lisheng Zhang, Suneet Kaur, Igor Nepliouev, Jonathan A. Stiber, Leigh Brian, Rui Qi, Virginia Wertman, Sudha K. Shenoy, Neil J. Freedman
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Oct; 38(10): 2295–2305. doi: 10.1161/ATVBAHA.118.311071
PMCID:
PMC6205742
AbstractArticlePDF–2.4M
17.
USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization
Chenming Wu, Kuntian Luo, Fei Zhao, Ping Yin, Ying Song, Min Deng, Jinzhou Huang, Yuping Chen, Lei Li, SeungBaek Lee, JungJin Kim, Qin Zhou, Xinyi Tu, Somaira Nowsheen, Qifeng Luo, Xiumei Gao, Zhenkun Lou, Zhongmin Liu, Jian Yuan
Cell Death Differ. 2018 Oct; 25(10): 1855–1869. Published online 2018 Jun 4. doi: 10.1038/s41418-018-0138-z
Correction in:
Cell Death Differ. 2023 Mar; 30(3): 857–858.
PMCID:
PMC6180113
AbstractArticlePDF–4.3M
18.
Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin
Jongchan Kim, Fatemeh Alavi Naini, Yutong Sun, Li Ma
Am J Cancer Res. 2018; 8(9): 1823–1836. Published online 2018 Sep 1.
PMCID:
PMC6176183
AbstractArticlePDF–3.1M
19.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
20.
Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
Dominika Kwasna, Syed Arif Abdul Rehman, Jayaprakash Natarajan, Stephen Matthews, Ross Madden, Virginia De Cesare, Simone Weidlich, Satpal Virdee, Ivan Ahel, Ian Gibbs-Seymour, Yogesh Kulathu
Mol Cell. 2018 Apr 5; 70(1): 150–164.e6. doi: 10.1016/j.molcel.2018.02.023
PMCID:
PMC5896202
AbstractArticle

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