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Select item 101536821.

Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid 11-Beta Dehydrogenase Type 2 (HSD11B2) Isoenzyme in Critically Ill Patients

Alice G. Vassiliou, Dimitra A. Vassiliadi, Chrysi Keskinidou, Edison Jahaj, Efi Botoula, Stylianos Tsagarakis, Anastasia Kotanidou, Ioanna Dimopoulou

Clin Med Res. 2023 Mar; 21(1): 6–13. doi: 10.3121/cmr.2023.1743

PMCID:: PMC10153682

Abstract Article PDF–1.1M

Select item 84194112.

Detection of Urinary Exosomal HSD11B2 mRNA Expression: A Useful Novel Tool for the Diagnostic Approach of Dysfunctional 11β-HSD2-Related Hypertension

Domenica De Santis, Annalisa Castagna, Elisa Danese, Silvia Udali, Nicola Martinelli, Francesca Morandini, Mariangela Veneri, Lorenzo Bertolone, Oliviero Olivieri, Simonetta Friso, Francesca Pizzolo

Front Endocrinol (Lausanne) 2021; 12: 681974. Published online 2021 Aug 23. doi: 10.3389/fendo.2021.681974

PMCID:: PMC8419411

Abstract Article PDF–617K

Select item 58615813.

11-Beta Dehydrogenase Type 2 Activity Is Not Reduced in Treatment Resistant Hypertension

Lama Ghazi, Tanja Dudenbostel, Maria El Hachem, Mohammed Siddiqui, Chee Paul Lin, Suzanne Oparil, David A. Calhoun

Am J Hypertens. 2017 May; 30(5): 518–523. Published online 2017 Feb 9. doi: 10.1093/ajh/hpx002

PMCID:: PMC5861581

Abstract Article PDF–229K

Select item 57482224.

Clinical, genetic, and structural basis of apparent mineralocorticoid excess due to 11β-hydroxysteroid dehydrogenase type 2 deficiency

Mabel Yau, Shozeb Haider, Ahmed Khattab, Chen Ling, Mehr Mathew, Samir Zaidi, Madison Bloch, Monica Patel, Sinead Ewert, Wafa Abdullah, Aysenur Toygar, Vitalii Mudryi, Maryam Al Badi, Mouch Alzubdi, Robert C. Wilson, Hanan Said Al Azkawi, Hatice Nur Ozdemir, Wahid Abu-Amer, Jozef Hertecant, Maryam Razzaghy-Azar, John W. Funder, Aisha Al Senani, Li Sun, Se-Min Kim, Tony Yuen, Mone Zaidi, Maria I. New

Proc Natl Acad Sci U S A. 2017 Dec 26; 114(52): E11248–E11256. Published online 2017 Dec 11. doi: 10.1073/pnas.1716621115

PMCID:: PMC5748222

Abstract Article PDF–3.1M

Select item 56256635.

Characterisation of the cancer-associated glucocorticoid system: key role of 11β-hydroxysteroid dehydrogenase type 2

Nicola Cirillo, David J Morgan, Maria Carmela Pedicillo, Antonio Celentano, Lorenzo Lo Muzio, Michael J McCullough, Stephen S Prime

Br J Cancer. 2017 Sep 26; 117(7): 984–993. Published online 2017 Aug 10. doi: 10.1038/bjc.2017.243

PMCID:: PMC5625663

Abstract Article PDF–1.9M

Select item 55519366.

Neurobehavior related to epigenetic differences in preterm infants

Barry M Lester, Carmen J Marsit, James Giarraputo, Katheleen Hawes, Linda L LaGasse, James F Padbury

Epigenomics. 2015 Oct; 7(7): 1123–1136. doi: 10.2217/epi.15.63

PMCID:: PMC5551936

Abstract Article PDF–1.4M

Select item 54952257.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 54180558.

A repressive role of enhancer of zeste homolog 2 in 11β-hydroxysteroid dehydrogenase type 2 expression in the human placenta

Rujuan Zuo, Xiaohui Liu, Wangsheng Wang, Wenjiao Li, Hao Ying, Kang Sun

J Biol Chem. 2017 May 5; 292(18): 7578–7587. Published online 2017 Mar 16. doi: 10.1074/jbc.M116.765800

PMCID:: PMC5418055

Abstract Article PDF–2.4M

Select item 54180529.

Rac1 GTPase regulates 11β hydroxysteroid dehydrogenase type 2 and fibrotic remodeling

Daniel Lavall, Pia Schuster, Nadine Jacobs, Andrey Kazakov, Michael Böhm, Ulrich Laufs

J Biol Chem. 2017 May 5; 292(18): 7542–7553. Published online 2017 Mar 20. doi: 10.1074/jbc.M116.764449

PMCID:: PMC5418052

Abstract Article PDF–2.3M

Select item 504200410.

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles

Anja E. Eisenhardt, Adrian Sprenger, Michael Röring, Ricarda Herr, Florian Weinberg, Martin Köhler, Sandra Braun, Joachim Orth, Britta Diedrich, Ulrike Lanner, Natalja Tscherwinski, Simon Schuster, Nicolas Dumaz, Enrico Schmidt, Ralf Baumeister, Andreas Schlosser, Jörn Dengjel, Tilman Brummer

Oncotarget. 2016 May 3; 7(18): 26628–26652. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8427

PMCID:: PMC5042004

Abstract Article PDF–7.5M

Select item 502641011.

Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior

Catherine Monk, Tianshu Feng, Seonjoo Lee, Izabela Krupska, Frances A. Champagne, Benjamin Tycko

Am J Psychiatry. Author manuscript; available in PMC 2016 Sep 16.

Published in final edited form as: Am J Psychiatry. 2016 Jul 1; 173(7): 705–713. Published online 2016 Mar 25. doi: 10.1176/appi.ajp.2015.15091171

PMCID:: PMC5026410

Abstract Article PDF–1.0M

Select item 484160712.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 477297113.

Placental epigenetic patterning of glucocorticoid response genes is associated with infant neurodevelopment

Alison G Paquette, Barry M Lester, Corina Lesseur, David A Armstrong, Dylan J Guerin, Allison A Appleton, Carmen J Marsit

Epigenomics. 2015 Aug; 7(5): 767–779. doi: 10.2217/epi.15.28

PMCID:: PMC4772971

Abstract Article PDF–1.9M

Select item 473387214.

The contributions of Maternal Sensitivity and Maternal Depressive Symptoms to Epigenetic Processes and Neuroendocrine Functioning

Elisabeth Conradt, Katheleen Hawes, Dylan Guerin, David A. Armstrong, Carmen J. Marsit, Edward Tronick, Barry M. Lester

Child Dev. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Child Dev. 2016 Jan; 87(1): 73–85. doi: 10.1111/cdev.12483

PMCID:: PMC4733872

Abstract Article PDF–805K

Select item 469852915.

Zearalenone Inhibits Rat and Human 11β-Hydroxysteroid Dehydrogenase Type 2

Linxi Li, Xiaolong Wu, Hongguo Guan, Baiping Mao, Huang Wang, Xiaohuan Yuan, Yanhui Chu, Jianliang Sun, Ren-Shan Ge

Biomed Res Int. 2015; 2015: 283530. Published online 2015 Dec 20. doi: 10.1155/2015/283530

PMCID:: PMC4698529

Abstract Article PDF–766K

Select item 466189216.

Maternal Prenatal Mental Health and Placental 11β-HSD2 Gene Expression: Initial Findings from the Mercy Pregnancy and Emotional Wellbeing Study

Sunaina Seth, Andrew James Lewis, Richard Saffery, Martha Lappas, Megan Galbally

Int J Mol Sci. 2015 Nov; 16(11): 27482–27496. Published online 2015 Nov 17. doi: 10.3390/ijms161126034

PMCID:: PMC4661892

Abstract Article PDF–524K

Select item 465261217.

The Role of Placental 11-Beta Hydroxysteroid Dehydrogenase Type 1 and Type 2 Methylation on Gene Expression and Infant Birth Weight

Benjamin B. Green, David A. Armstrong, Corina Lesseur, Alison G. Paquette, Dylan J. Guerin, Lauren E. Kwan, Carmen J. Marsit

Biol Reprod. 2015 Jun; 92(6): 149. Published online 2015 Mar 18. doi: 10.1095/biolreprod.115.128066

PMCID:: PMC4652612

Abstract Article PDF–479K

Select item 444426018.

Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways

Jian Chang, Min Xue, Shilin Yang, Bing Yao, Bixiang Zhang, Xiaoping Chen, Ambra Pozzi, Ming-Zhi Zhang

PLoS One. 2015; 10(5): e0127030. Published online 2015 May 26. doi: 10.1371/journal.pone.0127030

PMCID:: PMC4444260

Abstract Article PDF–13M

Select item 436391219.

Alteration in methylation level at 11β-hydroxysteroid dehydrogenase type 2 gene promoter in infants born to preeclamptic women

Wensheng Hu, Xiaoling Weng, Minyue Dong, Yun Liu, Wenjuan Li, Hefeng Huang

BMC Genet. 2014; 15: 96. Published online 2014 Sep 9. doi: 10.1186/s12863-014-0096-5

PMCID:: PMC4363912

Abstract Article PDF–316K

Select item 435065620.

Examining the joint contribution of placental NR3C1 and HSD11B2 methylation for infant neurobehavior

Allison A. Appleton, Barry M. Lester, David A. Armstrong, Corina Lesseur, Carmen J. Marsit

Psychoneuroendocrinology. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Psychoneuroendocrinology. 2015 Feb; 52: 32–42. Published online 2014 Nov 10. doi: 10.1016/j.psyneuen.2014.11.004

PMCID:: PMC4350656

Abstract Article PDF–326K

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