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Items: 1 to 20 of 94

1.
PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma
Song Peng, Ze Wang, Peng Tang, Shuo Wang, Yiqiang Huang, Qiubo Xie, Yapeng Wang, Xintao Tan, Tang Tang, Xuzhi Yan, Jing Xu, Weihua Lan, Luofu Wang, Dianzheng Zhang, Bin Wang, Tiejun Pan, Jun Qin, Jun Jiang, Qiuli Liu
Sci Adv. 2023 Aug; 9(31): eadf3566. Published online 2023 Aug 2. doi: 10.1126/sciadv.adf3566
PMCID:
PMC10396305
AbstractArticlePDF–2.7M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Single‐cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers
Jinfen Wei, Wenqi Yu, Juanzhi Chen, Guanda Huang, Lingjie Zhang, Zixi Chen, Meiling Hu, Xiaocheng Gong, Hongli Du
Mol Oncol. 2023 Apr; 17(4): 611–628. Published online 2023 Jan 21. doi: 10.1002/1878-0261.13373
PMCID:
PMC10061288
AbstractArticlePDF–15M
4.
Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation
Nicolás Campolo, Mauricio Mastrogiovanni, Michele Mariotti, Federico M. Issoglio, Darío Estrin, Per Hägglund, Tilman Grune, Michael J. Davies, Silvina Bartesaghi, Rafael Radi
J Biol Chem. 2023 Mar; 299(3): 102941. Published online 2023 Jan 23. doi: 10.1016/j.jbc.2023.102941
PMCID:
PMC10011836
AbstractArticlePDF–5.8M
5.
Bestrophin-2 and glutamine synthetase form a complex for glutamate release
Aaron P. Owji, Kuai Yu, Alec Kittredge, Jiali Wang, Yu Zhang, Tingting Yang
Nature. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Nature. 2022 Nov; 611(7934): 180–187. Published online 2022 Oct 26. doi: 10.1038/s41586-022-05373-x
PMCID:
PMC9873481
AbstractArticlePDF–3.6M
6.
Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway
Do Thi Minh Xuan, Chung-Che Wu, Wei-Jan Wang, Hui-Ping Hsu, Hoang Dang Khoa Ta, Gangga Anuraga, Chung-Chieh Chiao, Chih-Yang Wang
Int J Med Sci. 2023; 20(1): 35–49. Published online 2023 Jan 1. doi: 10.7150/ijms.75625
PMCID:
PMC9812810
AbstractArticlePDF–9.8M
7.
Glutamine synthetase limits β-catenin–mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1
Weiwei Dai, Jianliang Shen, Junrong Yan, Alex J. Bott, Sara Maimouni, Heineken Q. Daguplo, Yujue Wang, Khoosheh Khayati, Jessie Yanxiang Guo, Lanjing Zhang, Yongbo Wang, Alexander Valvezan, Wen-Xing Ding, Xin Chen, Xiaoyang Su, Shenglan Gao, Wei-Xing Zong
J Clin Invest. 2022 Dec 15; 132(24): e161408. Published online 2022 Dec 15. doi: 10.1172/JCI161408
PMCID:
PMC9754002
AbstractArticlePDF–34M
8.
MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer
Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang
Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x
PMCID:
PMC9523997
AbstractArticlePDF–6.9M
9.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
10.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
11.
Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex‐dependent regulation of glycolysis
Matthew E. R. Maitland, Miljan Kuljanin, Xu Wang, Gilles A. Lajoie, Caroline Schild‐Poulter
FASEB J. 2021 Sep; 35(9): e21825. Published online 2021 Aug 12. doi: 10.1096/fj.202100664R
PMCID:
PMC9292413
AbstractArticlePDF–1.5M
12.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
13.
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD–associated UBQLN2 mutants
Laura Strohm, Zehan Hu, Yongwon Suk, Alina Rühmkorf, Erin Sternburg, Vanessa Gattringer, Henrick Riemenschneider, Riccardo Berutti, Elisabeth Graf, Jochen H Weishaupt, Monika S Brill, Angelika B Harbauer, Dorothee Dormann, Jörn Dengjel, Dieter Edbauer, Christian Behrends
Life Sci Alliance. 2022 Nov; 5(11): e202101327. Published online 2022 Jul 1. doi: 10.26508/lsa.202101327
PMCID:
PMC9258132
AbstractArticlePDF–5.9M
14.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
15.
Tumor suppressor BAP1 nuclear import is governed by transportin-1
Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu
J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094
PMCID:
PMC9036092
AbstractArticlePDF–4.0M
16.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
17.
Crystal structure of N-terminal degron-truncated human glutamine synthetase
Min Fey Chek, Sun-Yong Kim, Tomoyuki Mori, Hisayuki Kojima, Toshio Hakoshima
Acta Crystallogr F Struct Biol Commun. 2021 Nov 1; 77(Pt 11): 427–434. Published online 2021 Oct 29. doi: 10.1107/S2053230X21010748
PMCID:
PMC8561813
AbstractArticlePDF–1.2M
18.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
19.
USP15 antagonizes CRL4CRBN-mediated ubiquitylation of glutamine synthetase and neosubstrates
Thang Van Nguyen
Proc Natl Acad Sci U S A. 2021 Oct 5; 118(40): e2111391118. Published online 2021 Sep 28. doi: 10.1073/pnas.2111391118
PMCID:
PMC8501880
AbstractArticlePDF–1.6M
20.
Hepatoblastoma: glutamine depletion hinders cell viability in the embryonal subtype but high GLUL expression is associated with better overall survival
Andreas Schmidt, Angela Armento, Ovidio Bussolati, Martina Chiu, Verena Ellerkamp, Marcus O. Scharpf, Philip Sander, Evi Schmid, Steven W. Warmann, Jörg Fuchs
J Cancer Res Clin Oncol. 2021; 147(11): 3169–3181. Published online 2021 Jul 7. doi: 10.1007/s00432-021-03713-4
PMCID:
PMC8484192
AbstractArticlePDF–1.4M

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