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Select item 102530021.

TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine

Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova

Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452

PMCID:: PMC10253002

Abstract Article PDF–2.4M

Select item 91374522.

Excess Neuropeptides in Lung Signal through Endothelial Cells to Impair Gas Exchange

Jinhao Xu, Le Xu, Pengfei Sui, Jiyuan Chen, Esteban A. Moya, Patrick Hume, William J. Janssen, Jason M. Duran, Patricia Thistlethwaite, Aaron Carlin, Peter Gulleman, Brandon Banaschewski, Mary Kate Goldy, Jason X.-J. Yuan, Atul Malhotra, Gloria Pryhuber, Laura Crotty-Alexander, Gail Deutsch, Lisa R. Young, Xin Sun

Dev Cell. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Dev Cell. 2022 Apr 11; 57(7): 839–853.e6. Published online 2022 Mar 17. doi: 10.1016/j.devcel.2022.02.023

PMCID:: PMC9137452

Abstract Article PDF–2.9M

Select item 86275993.

NF-κB determines Paneth versus goblet cell fate decision in the small intestine

Cristina Brischetto, Karsten Krieger, Christian Klotz, Inge Krahn, Séverine Kunz, Marina Kolesnichenko, Patrick Mucka, Julian Heuberger, Claus Scheidereit, Ruth Schmidt-Ullrich

Development. 2021 Nov 1; 148(21): dev199683. Published online 2021 Nov 9. doi: 10.1242/dev.199683

PMCID:: PMC8627599

Abstract Article

Select item 85428664.

An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

Elisabeth E. L. Nyström, Beatriz Martinez-Abad, Liisa Arike, George M. H. Birchenough, Eric B. Nonnecke, Patricia A. Castillo, Frida Svensson, Charles L. Bevins, Gunnar C. Hansson, Malin E. V. Johansson

Science. Author manuscript; available in PMC 2021 Oct 25.

Published in final edited form as: Science. 2021 Apr 16; 372(6539): eabb1590. doi: 10.1126/science.abb1590

PMCID:: PMC8542866

Abstract Article PDF–4.8M

Select item 72970585.

SPDEF Induces Quiescence of Colorectal Cancer Cells by Changing the Transcriptional Targets of β-catenin

Yuan-Hung Lo, Taeko K. Noah, Min-Shan Chen, Winnie Zou, Ester Borras, Eduardo Vilar, Noah F. Shroyer

Gastroenterology. Author manuscript; available in PMC 2020 Jun 16.

Published in final edited form as: Gastroenterology. 2017 Jul; 153(1): 205–218.e8. Published online 2017 Apr 5. doi: 10.1053/j.gastro.2017.03.048

PMCID:: PMC7297058

Abstract Article PDF–3.5M

Select item 69260516.

WNT/RYK signaling restricts goblet cell differentiation during lung development and repair

Hyun-Taek Kim, Wenguang Yin, Yuko Nakamichi, Paolo Panza, Beate Grohmann, Carmen Buettner, Stefan Guenther, Clemens Ruppert, Yasuhiro Kobayashi, Andreas Guenther, Didier Y. R. Stainier

Proc Natl Acad Sci U S A. 2019 Dec 17; 116(51): 25697–25706. Published online 2019 Nov 27. doi: 10.1073/pnas.1911071116

PMCID:: PMC6926051

Abstract Article PDF–2.9M

Select item 67632347.

IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis

Gang Chen, Ling Sun, Takafumi Kato, Kenichi Okuda, Mary B. Martino, Aiman Abzhanova, Jennifer M. Lin, Rodney C. Gilmore, Bethany D. Batson, Yvonne K. O’Neal, Allison S. Volmer, Hong Dang, Yangmei Deng, Scott H. Randell, Brian Button, Alessandra Livraghi-Butrico, Mehmet Kesimer, Carla M.P. Ribeiro, Wanda K. O’Neal, Richard C. Boucher

J Clin Invest. 2019 Oct 1; 129(10): 4433–4450. Published online 2019 Sep 16. doi: 10.1172/JCI125669

PMCID:: PMC6763234

Abstract Article PDF–32M

Select item 61896478.

Role of Spdef in the Regulation of Muc5b Expression in the Airways of Naive and Mucoobstructed Mice

Gang Chen, Allison S. Volmer, Kristen J. Wilkinson, Yangmei Deng, Lisa C. Jones, Dongfang Yu, Ximena M. Bustamante-Marin, Kimberlie A. Burns, Barbara R. Grubb, Wanda K. O’Neal, Alessandra Livraghi-Butrico, Richard C. Boucher

Am J Respir Cell Mol Biol. 2018 Sep; 59(3): 383–396. doi: 10.1165/rcmb.2017-0127OC

PMCID:: PMC6189647

Abstract Article PDF–3.7M

Select item 61537299.

Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells

Yangyan Xiao, Cintia S de Paiva, Zhiyuan Yu, Rodrigo G de Souza, De-Quan Li, Stephen C Pflugfelder

Int Immunol. 2018 Oct; 30(10): 457–470. Published online 2018 Jul 12. doi: 10.1093/intimm/dxy045

PMCID:: PMC6153729

Abstract Article PDF–3.4M

Select item 582118010.

Goblet cell loss abrogates ocular surface immune tolerance

Byung Yi Ko, Yangyan Xiao, Flavia L. Barbosa, Cintia S. de Paiva, Stephen C. Pflugfelder

JCI Insight. 2018 Feb 8; 3(3): e98222. Published online 2018 Feb 8. doi: 10.1172/jci.insight.98222

PMCID:: PMC5821180

Abstract Article PDF–2.4M

Select item 446320611.

Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation

Priya Rajavelu, Gang Chen, Yan Xu, Joseph A. Kitzmiller, Thomas R. Korfhagen, Jeffrey A. Whitsett

J Clin Invest. 2015 May 1; 125(5): 2021–2031. Published online 2015 Apr 13. doi: 10.1172/JCI79422

PMCID:: PMC4463206

Abstract Article PDF–3.8M

Select item 431955912.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 417781313.

SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

Xin-Hua Cheng, Markaisa Black, Vladimir Ustiyan, Tien Le, Logan Fulford, Anusha Sridharan, Mario Medvedovic, Vladimir V. Kalinichenko, Jeffrey A. Whitsett, Tanya V. Kalin

PLoS Genet. 2014 Sep; 10(9): e1004656. Published online 2014 Sep 25. doi: 10.1371/journal.pgen.1004656

PMCID:: PMC4177813

Abstract Article PDF–6.1M

Select item 414946714.

GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development

Emily M. Walker, Cayla A. Thompson, Michele A. Battle

Dev Biol. Author manuscript; available in PMC 2015 Aug 15.

Published in final edited form as: Dev Biol. 2014 Aug 15; 392(2): 283–294. Published online 2014 Jun 12. doi: 10.1016/j.ydbio.2014.05.017

PMCID:: PMC4149467

Abstract Article PDF–2.0M

Select item 391737115.

Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine

Boaz E Aronson, Kelly A Stapleton, Laurens ATM Vissers, Eva Stokhuijzen, Hanneke Bruijnzeel, Stephen D Krasinski

BMC Mol Biol. 2014; 15: 3. Published online 2014 Jan 28. doi: 10.1186/1471-2199-15-3

PMCID:: PMC3917371

Abstract Article PDF–1.6M

Select item 379774816.

The AERO System: A 3D-Like Approach for Recording Gene Expression Patterns in the Whole Mouse Embryo

Hirohito Shimizu, Atsushi Kubo, Kenta Uchibe, Megumi Hashimoto, Shigetoshi Yokoyama, Shuji Takada, Kazuhiko Mitsuoka, Hiroshi Asahara

PLoS One. 2013; 8(10): e75754. Published online 2013 Oct 16. doi: 10.1371/journal.pone.0075754

PMCID:: PMC3797748

Abstract Article PDF–564K

Select item 373806917.

SPDEF Functions as a Colorectal Tumor Suppressor by Inhibiting β-Catenin Activity

TAEKO K. NOAH, YUAN–HUNG LO, ALLISON PRICE, GANG CHEN, EILEEN KING, MARY–KAY WASHINGTON, BRUCE J. ARONOW, NOAH F. SHROYER

Gastroenterology. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Gastroenterology. 2013 May; 144(5): 1012–1023.e6. Published online 2013 Feb 1. doi: 10.1053/j.gastro.2013.01.043

PMCID:: PMC3738069

Abstract Article PDF–3.2M

Select item 370273518.

Spdef Null Mice Lack Conjunctival Goblet Cells and Provide a Model of Dry Eye

Christina K. Marko, Balaraj B. Menon, Gang Chen, Jeffrey A. Whitsett, Hans Clevers, Ilene K. Gipson

Am J Pathol. 2013 Jul; 183(1): 35–48. doi: 10.1016/j.ajpath.2013.03.017

PMCID:: PMC3702735

Abstract Article PDF–2.2M

Select item 357241019.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 350729320.

The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways

Olivier Boucherat, Jamila Chakir, Lucie Jeannotte

Biol Open. 2012 Jul 15; 1(7): 677–691. Published online 2012 May 29. doi: 10.1242/bio.20121701

PMCID:: PMC3507293

Abstract Article PDF–11M

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