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Items: 1 to 20 of 314

1.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
2.
Central nervous system anomalies in 41 Chinese children incontinentia pigmenti
Li Yin, Zhengyuan Li, Wenjuan Zhan, Yuanjie Kang, Qian Tian, Dan Li, Huifang Zhang
BMC Neurosci. 2024; 25: 25. Published online 2024 May 21. doi: 10.1186/s12868-024-00872-1
PMCID:
PMC11110290
AbstractArticlePDF–1.5M
3.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740
PMCID:
PMC11109483
AbstractArticlePDF–2.9M
4.
NEMO/NF-κB signaling functions as a double-edged sword in PanIN formation versus progression to pancreatic cancer
Miltiadis Tsesmelis, Ulrike F. G. Büttner, Melanie Gerstenlauer, Uta Manfras, Konstantinos Tsesmelis, Ziwei Du, Nadine Sperb, Stephanie Ellen Weissinger, Peter Möller, Thomas F. E. Barth, Harald J. Maier, Lap Kwan Chan, Thomas Wirth
Mol Cancer. 2024; 23: 103. Published online 2024 May 16. doi: 10.1186/s12943-024-01989-x
PMCID:
PMC11097402
AbstractArticlePDF–8.8M
5.
Dual regulation of NEMO by Nrf2 and miR-125a inhibits ferroptosis and protects liver from endoplasmic reticulum stress-induced injury
Jihoon Tak, Min Sung Joo, Yun Seok Kim, Hyun Woo Park, Chang Hoon Lee, Gil-Chun Park, Shin Hwang, Sang Geon Kim
Theranostics. 2024; 14(5): 1841–1859. Published online 2024 Feb 24. doi: 10.7150/thno.89703
PMCID:
PMC10945339
AbstractArticlePDF–12M
6.
A conserved core region of the scaffold NEMO is essential for signal-induced conformational change and liquid-liquid phase separation
Christopher J. DiRusso, Anthony M. DeMaria, Judy Wong, Wei Wang, Jack J. Jordanides, Adrian Whitty, Karen N. Allen, Thomas D. Gilmore
J Biol Chem. 2023 Dec; 299(12): 105396. Published online 2023 Oct 27. doi: 10.1016/j.jbc.2023.105396
PMCID:
PMC10694592
AbstractArticlePDF–4.1M
7.
Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
Olivia Harding, Elisabeth Holzer, Julia F. Riley, Sascha Martens, Erika L.F. Holzbaur
Mol Cell. Author manuscript; available in PMC 2024 Sep 7.
Published in final edited form as: Mol Cell. 2023 Sep 7; 83(17): 3188–3204.e7. doi: 10.1016/j.molcel.2023.08.005
PMCID:
PMC10510730
AbstractArticlePDF–4.0M
8.
TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation
Eunju Kim, Hyunchu Cho, Gaeul Lee, Heawon Baek, In Young Lee, Eui-Ju Choi
Mol Cells. 2023 Jul 31; 46(7): 430–440. Published online 2023 Jul 31. doi: 10.14348/molcells.2023.0026
PMCID:
PMC10336271
AbstractArticlePDF–1.9M
9.
The host antiviral protein SAMHD1 suppresses NF-κB activation by interacting with the IKK complex during inflammatory responses and viral infection
Hua Yang, Constanza E. Espada, Stacia Phillips, Nicholas Martinez, Adam D. Kenney, Jacob S. Yount, Yong Xiong, Li Wu
J Biol Chem. 2023 Jun; 299(6): 104750. Published online 2023 Apr 24. doi: 10.1016/j.jbc.2023.104750
PMCID:
PMC10318468
AbstractArticlePDF–4.9M
10.
A Conserved Core Region of the Scaffold NEMO is Essential for Signal-induced Conformational Change and Liquid-liquid Phase Separation
Christopher J. DiRusso, Anthony M. DeMaria, Judy Wong, Jack J. Jordanides, Adrian Whitty, Karen N. Allen, Thomas D. Gilmore
Version 1. bioRxiv. Preprint. 2023 May 25. doi: 10.1101/2023.05.25.542299
Published in:
J Biol Chem. 2023 Dec; 299(12): 105396.
PMCID:
PMC10245932
AbstractArticlePDF–1.9M
11.
IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death
Choong-Sil Lee, Gyuho Hwang, Young Woo Nam, Chi Hyun Hwang, Jaewhan Song
Cell Death Differ. 2023 Jun; 30(6): 1575–1584. Published online 2023 Apr 21. doi: 10.1038/s41418-023-01161-w
PMCID:
PMC10244383
AbstractArticlePDF–2.8M
12.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
13.
Molluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO
Thomas Phelan, Clara Lawler, Andreas Pichlmair, Mark A. Little, Andrew G. Bowie, Gareth Brady
J Virol. 2023 Mar; 97(3): e00108-23. Published online 2023 Mar 14. doi: 10.1128/jvi.00108-23
PMCID:
PMC10062130
AbstractArticlePDF–2.4M
14.
SARS-CoV-2 ORF3a positively regulates NF-κB activity by enhancing IKKβ-NEMO interaction
Ying Nie, Lumin Mou, Qizhou Long, Dongqing Deng, Rongying Hu, Jinzhi Cheng, Jiahong Wu
Virus Res. 2023 Apr 15; 328: 199086. Published online 2023 Mar 13. doi: 10.1016/j.virusres.2023.199086
PMCID:
PMC10009424
AbstractArticlePDF–3.3M
15.
CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection
Jing Zhang, Jing Ning, Weiwei Fu, Yanyan Shi, Jing Zhang, Shigang Ding
Gut Pathog. 2023; 15: 6. Published online 2023 Feb 13. doi: 10.1186/s13099-023-00533-4
PMCID:
PMC9924195
AbstractArticlePDF–4.5M
16.
Linear ubiquitination induces NEMO phase separation to activate NF-κB signaling
Simran Goel, Rosario Oliva, Sadasivam Jeganathan, Verian Bader, Laura J Krause, Simon Kriegler, Isabelle D Stender, Chadwick W Christine, Ken Nakamura, Jan-Erik Hoffmann, Roland Winter, Jörg Tatzelt, Konstanze F Winklhofer
Life Sci Alliance. 2023 Apr; 6(4): e202201607. Published online 2023 Jan 31. doi: 10.26508/lsa.202201607
PMCID:
PMC9889916
AbstractArticlePDF–2.9M
17.
A proteome-scale map of the SARS-CoV-2–human contactome
Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun
Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z
PMCID:
PMC9849141
AbstractArticlePDF–7.1M
18.
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus
Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer
EMBO J. 2022 Dec; 41(24): e112006. Published online 2022 Nov 18. doi: 10.15252/embj.2022112006
PMCID:
PMC9753471
AbstractArticlePDF–4.3M
19.
Stress response protein REDD1 promotes diabetes-induced retinal inflammation by sustaining canonical NF-κB signaling
Siddharth Sunilkumar, Allyson L. Toro, Christopher M. McCurry, Ashley M. VanCleave, Shaunaci A. Stevens, William P. Miller, Scot R. Kimball, Michael D. Dennis
J Biol Chem. 2022 Dec; 298(12): 102638. Published online 2022 Oct 26. doi: 10.1016/j.jbc.2022.102638
PMCID:
PMC9694114
AbstractArticlePDF–2.0M
20.
Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro
Mikhail A. Hameedi, Erica T. Prates, Michael R. Garvin, Irimpan I. Mathews, B. Kirtley Amos, Omar Demerdash, Mark Bechthold, Mamta Iyer, Simin Rahighi, Daniel W. Kneller, Andrey Kovalevsky, Stephan Irle, Van-Quan Vuong, Julie C. Mitchell, Audrey Labbe, Stephanie Galanie, Soichi Wakatsuki, Daniel Jacobson
Nat Commun. 2022; 13: 5285. Published online 2022 Sep 8. doi: 10.1038/s41467-022-32922-9
PMCID:
PMC9453703
AbstractArticlePDF–2.2M

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