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Select item 80384511.

DNA Methylation Patterns Correlate with the Expression of SCNN1A, SCNN1B, and SCNN1G (Epithelial Sodium Channel, ENaC) Genes

Silvia Pierandrei, Gessica Truglio, Fabrizio Ceci, Paola Del Porto, Sabina Maria Bruno, Stefano Castellani, Massimo Conese, Fiorentina Ascenzioni, Marco Lucarelli

Int J Mol Sci. 2021 Apr; 22(7): 3754. Published online 2021 Apr 4. doi: 10.3390/ijms22073754

PMCID:: PMC8038451

Abstract Article PDF–2.5M

Select item 73681682.

Pediatric Liddle Syndrome Caused by a Novel SCNN1G Variant in a Chinese Family and Characterized by Early-Onset Hypertension

Peng Fan, Xiao-Cheng Pan, Di Zhang, Kun-Qi Yang, Ying Zhang, Tao Tian, Fang Luo, Wen-Jun Ma, Ya-Xin Liu, Lin-Ping Wang, Hui-Min Zhang, Lei Song, Jun Cai, Xian-Liang Zhou

Am J Hypertens. 2020 Jul; 33(7): 670–675. Published online 2020 Mar 12. doi: 10.1093/ajh/hpaa037

PMCID:: PMC7368168

Abstract Article PDF–456K

Select item 72783533.

Phosphatidylinositol 4,5-bisphosphate directly interacts with the β and γ subunits of the sodium channel ENaC

Crystal R. Archer, Benjamin T. Enslow, Chase M. Carver, James D. Stockand

J Biol Chem. 2020 Jun 5; 295(23): 7958–7969. Published online 2020 Apr 27. doi: 10.1074/jbc.RA120.012606

PMCID:: PMC7278353

Abstract Article PDF–3.1M

Select item 70135634.

Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption

Praveen Kumar Nattramilarasu, Roland Bücker, Fábia Daniela Lobo de Sá, Anja Fromm, Oliver Nagel, In-Fah Maria Lee, Eduard Butkevych, Soraya Mousavi, Claudia Genger, Sigri Kløve, Markus M. Heimesaat, Stefan Bereswill, Michal R. Schweiger, Hans Linde Nielsen, Hanno Troeger, Jörg-Dieter Schulzke

Int J Mol Sci. 2020 Jan; 21(2): 373. Published online 2020 Jan 7. doi: 10.3390/ijms21020373

PMCID:: PMC7013563

Abstract Article PDF–4.0M

Select item 68154635.

Liddle syndrome due to a novel mutation in the γ subunit of the epithelial sodium channel (ENaC) in family from Russia: a case report

Anastasiya A. Kozina, Tatiana A. Trofimova, Elena G. Okuneva, Natalia V. Baryshnikova, Varvara A. Obuhova, Anna Yu. Krasnenko, Kirill Yu. Tsukanov, Olesya I. Klimchuk, Ekaterina I. Surkova, Peter A. Shatalov, Valery V. Ilinsky

BMC Nephrol. 2019; 20: 389. Published online 2019 Oct 26. doi: 10.1186/s12882-019-1579-4

PMCID:: PMC6815463

Abstract Article PDF–1005K

Select item 61666826.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 60777227.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 60289868.

Epithelial Na⁺ Channel: Reciprocal Control by COMMD10 and Nedd4-2

Adam W. Ware, Tanya T. Cheung, Sahib Rasulov, Ezra Burstein, Fiona J. McDonald

Front Physiol. 2018; 9: 793. Published online 2018 Jun 26. doi: 10.3389/fphys.2018.00793

PMCID:: PMC6028986

Abstract Article PDF–4.0M

Select item 59864929.

Association of Genetic Variation in the Epithelial Sodium Channel Gene with Urinary Sodium Excretion and Blood Pressure

Yoon Jung Yang, Jihye Kim, Chang Keun Kwock

Nutrients. 2018 May; 10(5): 612. Published online 2018 May 14. doi: 10.3390/nu10050612

PMCID:: PMC5986492

Abstract Article PDF–250K

Select item 586153710.

Resequencing Epithelial Sodium Channel Genes Identifies Rare Variants Associated With Blood Pressure Salt-Sensitivity: The GenSalt Study

Xiaoying Gu, Dongfeng Gu, Jiang He, Dabeeru C Rao, James E Hixson, Jichun Chen, Jianxin Li, Jianfeng Huang, Xigui Wu, Treva K Rice, Lawrence C Shimmin, Tanika N Kelly

Am J Hypertens. 2018 Jan; 31(2): 205–211. Published online 2017 Sep 19. doi: 10.1093/ajh/hpx169

PMCID:: PMC5861537

Abstract Article PDF–377K

Select item 584613811.

Mapping allosteric linkage to channel gating by extracellular domains in the human epithelial sodium channel

Mahmoud Shobair, Konstantin I. Popov, Yan L. Dang, Hong He, M. Jackson Stutts, Nikolay V. Dokholyan

J Biol Chem. 2018 Mar 9; 293(10): 3675–3684. Published online 2018 Jan 22. doi: 10.1074/jbc.RA117.000604

PMCID:: PMC5846138

Abstract Article PDF–1.4M

Select item 542378412.

Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein

Teresa M. Buck, Alexa S. Jordahl, Megan E. Yates, G. Michael Preston, Emily Cook, Thomas R. Kleyman, Jeffrey L. Brodsky

Biochem J. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Biochem J. 2017 Feb 1; 474(3): 357–376. Published online 2016 Nov 30. doi: 10.1042/BCJ20160760

PMCID:: PMC5423784

Abstract Article PDF–1.8M

Select item 503652713.

Panorama of ancient metazoan macromolecular complexes

Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Nature. Author manuscript; available in PMC 2016 Sep 26.

Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877

PMCID:: PMC5036527

Abstract Article PDF–4.7M

Select item 487506114.

Liddle-Mutation of the β-Subunit, but not the γ-Subunit, Attenuates Protein Kinase C-Mediated Inhibition of Human Epithelial Sodium Channels (hENaC)

Gerard G. Robins, Geoffrey I. Sandle

J Membr Biol. 2016; 249: 271–279. Published online 2016 Jan 12. doi: 10.1007/s00232-015-9866-x

PMCID:: PMC4875061

Abstract Article PDF–465K

Select item 475665715.

Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseases

Israel Hanukoglu, Aaron Hanukoglu

Gene. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: Gene. 2016 Apr 1; 579(2): 95–132. Published online 2016 Jan 7. doi: 10.1016/j.gene.2015.12.061

PMCID:: PMC4756657

Abstract Article PDF–8.2M

Select item 459531016.

A potential role for interleukin-33 and γ-epithelium sodium channel in the pathogenesis of human malaria associated lung injury

Sumate Ampawong, Urai Chaisri, Parnpen Viriyavejakul, Panote Prapansilp, Georges E. Grau, Gareth D. H. Turner, Emsri Pongponratn

Malar J. 2015; 14: 389. Published online 2015 Oct 5. doi: 10.1186/s12936-015-0922-x

PMCID:: PMC4595310

Abstract Article PDF–2.8M

Select item 435754617.

Associations of epithelial sodium channel genes with blood pressure: the GenSalt study

Fangchao Liu, Xueli Yang, Xingbo Mo, Jianfeng Huang, Jing Chen, Tanika N Kelly, James E. Hixson, Dabeeru C. Rao, Charles C. Gu, Lawrence C. Shimmin, Jichun Chen, Treva K. Rice, Jianxin Li, Karen Schwander, Jiang He, De-pei Liu, DongfengGu

J Hum Hypertens. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: J Hum Hypertens. 2015 Apr; 29(4): 224–228. Published online 2014 Sep 18. doi: 10.1038/jhh.2014.78

PMCID:: PMC4357546

Abstract Article PDF–2.3M

Select item 434244518.

Proteolytic Regulation of Epithelial Sodium Channels by Urokinase Plasminogen Activator: CUTTING EDGE AND CLEAVAGE SITES

Hong-Long Ji, Runzhen Zhao, Andrey A. Komissarov, Yongchang Chang, Yongfeng Liu, Michael A. Matthay

J Biol Chem. 2015 Feb 27; 290(9): 5241–5255. Published online 2015 Jan 2. doi: 10.1074/jbc.M114.623496

PMCID:: PMC4342445

Abstract Article PDF–2.6M

Select item 427973519.

The Epithelial Sodium Channel γ-Subunit Is Processed Proteolytically in Human Kidney

Rikke M. Zachar, Karsten Skjødt, Niels Marcussen, Steen Walter, Anja Toft, Maria R. Nielsen, Boye L. Jensen, Per Svenningsen

J Am Soc Nephrol. 2015 Jan; 26(1): 95–106. Published online 2014 Jul 24. doi: 10.1681/ASN.2013111173

PMCID:: PMC4279735

Abstract Article

Select item 426394020.

Associations of Epithelial Sodium Channel Genes With Blood Pressure Changes and Hypertension Incidence: The GenSalt Study

Xueli Yang, Jiang He, Dongfeng Gu, James E. Hixson, Jianfeng Huang, Dabeeru C. Rao, Lawrence C. Shimmin, Jichun Chen, Treva K. Rice, Jianxin Li, Karen Schwander, Tanika N. Kelly

Am J Hypertens. 2014 Nov; 27(11): 1370–1376. Published online 2014 Apr 15. doi: 10.1093/ajh/hpu060

PMCID:: PMC4263940

Abstract Article PDF–725K

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