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Select item 110909361.

The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer

Cristina Di Giorgio, Rachele Bellini, Antonio Lupia, Carmen Massa, Ginevra Urbani, Martina Bordoni, Silvia Marchianò, Rosalinda Rosselli, Rosa De Gregorio, Pasquale Rapacciuolo, Valentina Sepe, Elva Morretta, Maria Chiara Monti, Federica Moraca, Luigi Cari, Khan Rana Sami Ullah, Nicola Natalizi, Luigina Graziosi, Eleonora Distrutti, Michele Biagioli, Bruno Catalanotti, Annibale Donini, Angela Zampella, Stefano Fiorucci

Cell Oncol (Dordr) 2024; 47(2): 695–710. Published online 2023 Nov 9. doi: 10.1007/s13402-023-00893-8

PMCID:: PMC11090936

Abstract Article PDF–13M

Select item 105661132.

The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression

Nianli Liu, Jinqiang Zhang, Weina Chen, Wenbo Ma, Tong Wu

J Exp Clin Cancer Res. 2023; 42: 263. Published online 2023 Oct 11. doi: 10.1186/s13046-023-02844-5

PMCID:: PMC10566113

Abstract Article PDF–2.6M

Select item 100729063.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 100087334.

FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC

Xilang Chen, Jie Chen, Weibo Feng, Wenjie Huang, Guodong Wang, Mengyu Sun, Xiangyuan Luo, Yijun Wang, Yongzhan Nie, Daiming Fan, Kaichun Wu, Limin Xia

Theranostics. 2023; 13(4): 1401–1418. Published online 2023 Feb 22. doi: 10.7150/thno.82269

PMCID:: PMC10008733

Abstract Article PDF–16M

Select item 96291355.

Induction of Fibroblast Growth Factor Receptor 4 by Helicobacter pylori via Signal Transducer and Activator of Transcription 3 With a Feedforward Activation Loop Involving Steroid Receptor Coactivator Signaling in Gastric Cancer

Xing Zhang, Mohammed Soutto, Zheng Chen, Nadeem Bhat, Shoumin Zhu, Moritz F. Eissmann, Matthias Ernst, Heng Lu, Dunfa Peng, Zekuan Xu, Wael El-Rifai

Gastroenterology. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Gastroenterology. 2022 Sep; 163(3): 620–636.e9. Published online 2022 May 17. doi: 10.1053/j.gastro.2022.05.016

PMCID:: PMC9629135

Abstract Article PDF–3.3M

Select item 95050026.

FGFR1–4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer

Joanna Moes-Sosnowska, Monika Skupinska, Urszula Lechowicz, Ewa Szczepulska-Wojcik, Paulina Skronska, Adriana Rozy, Aneta Stepniewska, Renata Langfort, Piotr Rudzinski, Tadeusz Orlowski, Delfina Popiel, Aleksandra Stanczak, Maciej Wieczorek, Joanna Chorostowska-Wynimko

Int J Mol Sci. 2022 Sep; 23(18): 10506. Published online 2022 Sep 10. doi: 10.3390/ijms231810506

PMCID:: PMC9505002

Abstract Article PDF–4.2M

Select item 92316237.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91714118.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 91066949.

N6-methyladenosine regulated FGFR4 attenuates ferroptotic cell death in recalcitrant HER2-positive breast cancer

Yutian Zou, Shaoquan Zheng, Xinhua Xie, Feng Ye, Xiaoqian Hu, Zhi Tian, Shu-Mei Yan, Lu Yang, Yanan Kong, Yuhui Tang, Wenwen Tian, Jindong Xie, Xinpei Deng, Yan Zeng, Zhe-Sheng Chen, Hailin Tang, Xiaoming Xie

Nat Commun. 2022; 13: 2672. Published online 2022 May 13. doi: 10.1038/s41467-022-30217-7

PMCID:: PMC9106694

Abstract Article PDF–8.4M

Select item 894064510.

Glycosylation of FGFR4 in cholangiocarcinoma regulates receptor processing and cancer signaling

Andrew J. Phillips, Marissa B. Lobl, Yamnah A. Hafeji, Hannah R. Safranek, Ashley M. Mohr, Justin L. Mott

J Cell Biochem. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: J Cell Biochem. 2022 Mar; 123(3): 568–580. Published online 2022 Jan 4. doi: 10.1002/jcb.30204

PMCID:: PMC8940645

Abstract Article PDF–2.5M

Select item 869917111.

Role of FGF Receptors and Their Pathways in Adrenocortical Tumors and Possible Therapeutic Implications

Iuliu Sbiera, Stefan Kircher, Barbara Altieri, Kerstin Lenz, Constanze Hantel, Martin Fassnacht, Silviu Sbiera, Matthias Kroiss

Front Endocrinol (Lausanne) 2021; 12: 795116. Published online 2021 Dec 9. doi: 10.3389/fendo.2021.795116

PMCID:: PMC8699171

Abstract Article PDF–4.0M

Select item 836820212.

Molecular mechanisms of the anti-cancer drug, LY2874455, in overcoming the FGFR4 mutation-based resistance

Fariba Dehghanian, Shahryar Alavi

Sci Rep. 2021; 11: 16593. Published online 2021 Aug 16. doi: 10.1038/s41598-021-96159-0

PMCID:: PMC8368202

Abstract Article PDF–1.4M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 780946414.

Effects of FGFR4 G388R, V10I polymorphisms on the likelihood of cancer

Tao Peng, Yangyang Sun, Zhiwei Lv, Ze Zhang, Quanxin Su, Hao Wu, Wei Zhang, Wei Yuan, Li Zuo, Li Shi, Li-Feng Zhang, Xiaoli Zhou, Yuanyuan Mi

Sci Rep. 2021; 11: 1373. Published online 2021 Jan 14. doi: 10.1038/s41598-020-80146-y

PMCID:: PMC7809464

Abstract Article PDF–4.8M

Select item 767564715.

Comparison of Benign and Malignant Pilomatricomas Using Whole-exome Sequencing

MIN-KYUNG YEO, GO EUN BAE

Cancer Genomics Proteomics. 2020 Nov-Dec; 17(6): 795–802. Published online 2020 Nov 3. doi: 10.21873/cgp.20233

PMCID:: PMC7675647

Abstract Article PDF–9.5M

Select item 758481516.

An updated meta-analysis of the association between fibroblast growth factor receptor 4 polymorphisms and susceptibility to cancer

Abdolkarim Moazeni-Roodi, Sahel Sarabandi, Shima Karami, Mohammad Hashemi, Saeid Ghavami

Biosci Rep. 2020 Oct 30; 40(10): BSR20192051. Published online 2020 Oct 23. doi: 10.1042/BSR20192051

PMCID:: PMC7584815

Abstract Article PDF–1.2M

Select item 757782217.

FGFR4 Gly388Arg Polymorphism Affects the Progression of Gastric Cancer by Activating STAT3 Pathway to Induce Epithelial to Mesenchymal Transition

Yanwei Ye, Jie Li, Dongbao Jiang, Jingjing Li, Chuangfeng Xiao, Yingze Li, Chao Han, Chunlin Zhao

Cancer Res Treat. 2020 Oct; 52(4): 1162–1177. Published online 2020 May 25. doi: 10.4143/crt.2020.138

PMCID:: PMC7577822

Abstract Article PDF–5.1M

Select item 755396918.

Influence of NOS3 rs2070744 genotypes on hepatocellular carcinoma patients treated with lenvatinib

Shintaro Azuma, Haruki Uojima, Makoto Chuma, Xue Shao, Hisashi Hidaka, Takahide Nakazawa, Masaaki Kondo, Kazushi Numata, Shogo Iwabuchi, Makoto Kako, Shin Maeda, Wasaburo Koizumi, Koichiro Atsuda

Sci Rep. 2020; 10: 17054. Published online 2020 Oct 13. doi: 10.1038/s41598-020-73930-3

Correction in:: Sci Rep. 2021; 11: 8550.

PMCID:: PMC7553969

Abstract Article PDF–1.1M

Select item 746045719.

FGFR4 Gene Polymorphism Reduces the Risk of Distant Metastasis in Lung Adenocarcinoma in Taiwan

Ju-Pi Li, Hsien-Cheng Huang, Po-Jen Yang, Chien-Yuan Chang, Yu-Hua Chao, Thomas Chang-Yao Tsao, Hsuan Huang, Yu-Ching Hung, Ming-Ju Hsieh, Shun-Fa Yang

Int J Environ Res Public Health. 2020 Aug; 17(16): 5694. Published online 2020 Aug 6. doi: 10.3390/ijerph17165694

PMCID:: PMC7460457

Abstract Article PDF–677K

Select item 745624720.

FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease

Susana Garcia-Recio, Aatish Thennavan, Michael P. East, Joel S. Parker, Juan M. Cejalvo, Joseph P. Garay, Daniel P. Hollern, Xiaping He, Kevin R. Mott, Patricia Galván, Cheng Fan, Sara R. Selitsky, Alisha R. Coffey, David Marron, Fara Brasó-Maristany, Octavio Burgués, Joan Albanell, Federico Rojo, Ana Lluch, Eduardo Martinez de Dueñas, Jeffery M. Rosen, Gary L. Johnson, Lisa A. Carey, Aleix Prat, Charles M. Perou

J Clin Invest. 2020 Sep 1; 130(9): 4871–4887. Published online 2020 Aug 17. doi: 10.1172/JCI130323

PMCID:: PMC7456247

Abstract Article PDF–10M

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