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Items: 1 to 20 of 27

1.
IL-11 system participates in pulmonary artery remodeling and hypertension in pulmonary fibrosis
Javier Milara, Inés Roger, Paula Montero, Enrique Artigues, Juan Escrivá, Julio Cortijo
Respir Res. 2022; 23: 313. Published online 2022 Nov 15. doi: 10.1186/s12931-022-02241-0
PMCID:
PMC9664718
AbstractArticlePDF–6.2M
2.
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts
Eleonora Adami, Sivakumar Viswanathan, Anissa A Widjaja, Benjamin Ng, Sonia Chothani, Nevin Zhihao, Jessie Tan, Pei Min Lio, Benjamin L George, Umut Altunoglu, Kakaly Ghosh, Bhairav S Paleja, Sebastian Schafer, Bruno Reversade, Salvatore Albani, Andrea Low Hsiu Ling, Steven O'Reilly, Stuart A Cook
Rheumatology (Oxford) 2021 Dec; 60(12): 5820–5826. Published online 2021 Feb 16. doi: 10.1093/rheumatology/keab168
PMCID:
PMC8645270
AbstractArticlePDF–792K
3.
Interleukin-11 receptor expression on monocytes is dispensable for their recruitment and pathogen uptake during Leishmania major infection
Iris Baars, Juliane Lokau, Ina Sauerland, Andreas J. Müller, Christoph Garbers
Cytokine. 2021 Dec; 148: None. doi: 10.1016/j.cyto.2021.155699
PMCID:
PMC8560641
AbstractArticle
4.
The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement
Riley D. Metcalfe, Kaheina Aizel, Courtney O. Zlatic, Paul M. Nguyen, Craig J. Morton, Daisy Sio-Seng Lio, Heung-Chin Cheng, Renwick C. J. Dobson, Michael W. Parker, Paul R. Gooley, Tracy L. Putoczki, Michael D. W. Griffin
J Biol Chem. 2020 Jun 12; 295(24): 8285–8301. Published online 2020 Apr 24. doi: 10.1074/jbc.RA119.012351
PMCID:
PMC7294085
AbstractArticlePDF–3.5M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
miR-23b inhibits proliferation of SMMC-7721 cells by directly targeting IL-11
Tianpeng Jiang, Zhi Huang, Shuai Zhang, Weijie Zou, Lei Xiang, Xiaowen Wu, Yaping Shen, Weixin Liu, Zhu Zeng, Ansu Zhao, Shi Zhou, Qingfan Zeng
Mol Med Rep. 2018 Aug; 18(2): 1591–1599. Published online 2018 Jun 11. doi: 10.3892/mmr.2018.9151
PMCID:
PMC6072194
AbstractArticlePDF–1.7M
7.
The length of the interleukin-11 receptor stalk determines its capacity for classic signaling
Juliane Lokau, Christoph Garbers
J Biol Chem. 2018 Apr 27; 293(17): 6398–6409. Published online 2018 Mar 9. doi: 10.1074/jbc.RA118.001879
PMCID:
PMC5925790
AbstractArticlePDF–3.5M
8.
Therapeutically blocking interleukin-11 receptor-α enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours
Amy Winship, Michelle Van Sinderen, Katarzyna Rainczuk, Evdokia Dimitriadis
Oncotarget. 2017 Apr 4; 8(14): 22716–22729. Published online 2017 Feb 8. doi: 10.18632/oncotarget.15187
PMCID:
PMC5410257
AbstractArticlePDF–12M
9.
Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway
Leilei Tao, Guichun Huang, Rui Wang, Yan Pan, Zhenyue He, Xiaoyuan Chu, Haizhu Song, Longbang Chen
Sci Rep. 2016; 6: 38408. Published online 2016 Dec 6. doi: 10.1038/srep38408
PMCID:
PMC5138853
AbstractArticlePDF–2.5M
10.
Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines
Danielle Queiroz Calcagno, Sylvia Santomi Takeno, Carolina Oliveira Gigek, Mariana Ferreira Leal, Fernanda Wisnieski, Elizabeth Suchi Chen, Taíssa Maíra Thomaz Araújo, Eleonidas Moura Lima, Maria Isabel Melaragno, Samia Demachki, Paulo Pimentel Assumpção, Rommel Rodriguez Burbano, Marília Cardoso Smith
World J Gastroenterol. 2016 Nov 21; 22(43): 9506–9514. Published online 2016 Nov 21. doi: 10.3748/wjg.v22.i43.9506
PMCID:
PMC5116594
AbstractArticlePDF–1.0M
11.
Genetically Modified T Cells Targeting Interleukin-11 Receptor α-Chain Kill Human Osteosarcoma Cells and Induce the Regression of Established Osteosarcoma Lung Metastases
Gangxiong Huang, Ling Yu, Laurence JN Cooper, Mario Hollomon, Helen Huls, Eugenie S Kleinerman
Cancer Res. Author manuscript; available in PMC 2013 Nov 19.
Published in final edited form as: Cancer Res. 2012 Jan 1; 72(1): 10.1158/0008-5472.CAN-11-2778. Published online 2011 Nov 10. doi: 10.1158/0008-5472.CAN-11-2778
PMCID:
PMC3833671
AbstractArticlePDF–4.2M
12.
A designer hyper interleukin 11 (H11) is a biologically active cytokine
Hanna Dams-Kozlowska, Katarzyna Gryska, Eliza Kwiatkowska-Borowczyk, Dariusz Izycki, Stefan Rose-John, Andrzej Mackiewicz
BMC Biotechnol. 2012; 12: 8. Published online 2012 Mar 21. doi: 10.1186/1472-6750-12-8
PMCID:
PMC3382428
AbstractArticlePDF–1.2M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Risk of Meningioma and Common Variation in Genes related to Innate Immunity
Preetha Rajaraman, Alina V. Brenner, Gila Neta, Ruth Pfeiffer, Sophia S. Wang, Meredith Yeager, Gilles Thomas, Howard A. Fine, Martha S. Linet, Nathaniel Rothman, Stephen J. Chanock, Peter D. Inskip
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Sep 7.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5): 1356–1361. Published online 2010 Apr 20. doi: 10.1158/1055-9965.EPI-09-1151
PMCID:
PMC3169167
AbstractArticlePDF–61K
15.
Inactivation of IL11 Signaling Causes Craniosynostosis, Delayed Tooth Eruption, and Supernumerary Teeth
Pekka Nieminen, Neil V. Morgan, Aimée L. Fenwick, Satu Parmanen, Lotta Veistinen, Marja L. Mikkola, Peter J. van der Spek, Andrew Giraud, Louise Judd, Sirpa Arte, Louise A. Brueton, Steven A. Wall, Irene M.J. Mathijssen, Eamonn R. Maher, Andrew O.M. Wilkie, Sven Kreiborg, Irma Thesleff
Am J Hum Genet. 2011 Jul 15; 89(1): 67–81. doi: 10.1016/j.ajhg.2011.05.024
PMCID:
PMC3135804
AbstractArticlePDF–1.5M
16.
Polymorphisms in innate immunity genes and risk of childhood leukemia
Sohee Han, Qing Lan, Ae Kyung Park, Kyoung-Mu Lee, Sue K. Park, Hyo Seop Ahn, Hee Young Shin, Hyoung Jin Kang, Hong Hoe Koo, Jong Jin Seo, Ji Eun Choi, Yoon-Ok Ahn, Stephen J. Chanock, Ho Kim, Nathaniel Rothman, Daehee Kang
Hum Immunol. Author manuscript; available in PMC 2010 Nov 2.
Published in final edited form as: Hum Immunol. 2010 Jul; 71(7): 727–730. Published online 2010 May 16. doi: 10.1016/j.humimm.2010.04.004
PMCID:
PMC2967770
AbstractArticlePDF–306K
17.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
18.
Interleukin 11 is upregulated in uterine lavage and endometrial cancer cells in women with endometrial carcinoma
Joanne Yap, Lois A Salamonsen, Tom Jobling, Peter K Nicholls, Evdokia Dimitriadis
Reprod Biol Endocrinol. 2010; 8: 63. Published online 2010 Jun 17. doi: 10.1186/1477-7827-8-63
PMCID:
PMC2901310
AbstractArticlePDF–2.0M
19.
Interleukin 11 Inhibits Human Trophoblast Invasion Indicating a Likely Role in the Decidual Restraint of Trophoblast Invasion During Placentation
Premila Paiva, Lois A. Salamonsen, Ursula Manuelpillai, Evdokia Dimitriadis
Biol Reprod. 2009 Feb; 80(2): 302–310. Prepublished online 2008 Nov 5. doi: 10.1095/biolreprod.108.071415
PMCID:
PMC2848732
AbstractArticlePDF–630K
20.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M

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