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Select item 109952081.

Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis

Chuan Yang, Xueping Wang, Kenneth K. W. To, Caimei Cui, Min Luo, Shaocong Wu, Lamei Huang, Kai Fu, Can Pan, Zeyu Liu, Teng Fan, Caibo Yang, Fang Wang, Liwu Fu

Signal Transduct Target Ther. 2024; 9: 84. Published online 2024 Apr 5. doi: 10.1038/s41392-024-01789-1

PMCID:: PMC10995208

Abstract Article PDF–7.0M

Select item 106675272.

PTPRC functions as a prognosis biomarker in the tumor microenvironment of cutaneous melanoma

Xuemei Li, Zhanghui Yue, Dan Wang, Lu Zhou

Sci Rep. 2023; 13: 20617. Published online 2023 Nov 23. doi: 10.1038/s41598-023-46794-6

PMCID:: PMC10667527

Abstract Article PDF–13M

Select item 106545663.

Plasma-derived extracellular vesicle surface markers CD45, CD326 and CD56 correlate with the stage of osteoarthritis: a primary study of a novel and promising diagnostic tool of the disease

Jana Matejova, Livia K. Fecskeova, Lucia Slovinska, Denisa Harvanova, Timea Spakova, Jana Bzdilova

Sci Rep. 2023; 13: 20071. Published online 2023 Nov 16. doi: 10.1038/s41598-023-47074-z

PMCID:: PMC10654566

Abstract Article PDF–2.8M

Select item 103782414.

CD45RA and CD45RO Are Regulated in a Cell-Type Specific Manner in Inflammation and Sepsis

Muhammad G. T. Ahmed, Andreas Limmer, Matthias Hartmann

Cells. 2023 Jul; 12(14): 1873. Published online 2023 Jul 17. doi: 10.3390/cells12141873

PMCID:: PMC10378241

Abstract Article PDF–2.9M

Select item 101330275.

CD45 is sufficient to initiate EndMT in human endothelial cells

Sana Nasim, Jill Wylie-Sears, Xinlei Gao, Qianman Peng, Bo Zhu, Kaifu Chen, Hong Chen, Joyce Bischoff

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2023 May; 43(5): e124–e131. Published online 2023 Mar 16. doi: 10.1161/ATVBAHA.122.318172

PMCID:: PMC10133027

Abstract Article PDF–1.4M

Select item 99783156.

Upregulation of PTPRC and Interferon Response Pathways in HIV-1 Seroconverters Prior to Infection

Yunqi Li, Francois Lefebvre, Edith Nakku-Joloba, Allan Ronald, Glenda Gray, Guy de Bruyn, James Kiarie, Connie Celum, Mark J Cameron, Jairam R Lingappa, Romel D Mackelprang

J Infect Dis. 2023 Mar 1; 227(5): 714–719. Published online 2023 Jan 13. doi: 10.1093/infdis/jiac498

PMCID:: PMC9978315

Abstract Article PDF–575K

Select item 92035797.

Low transcriptomic of PTPRCv1 and CD3E is an independent predictor of mortality in HIV and tuberculosis co-infected patient

Gebremedhin Gebremicael, Atsbeha Gebreegziabxier, Desta Kassa

Sci Rep. 2022; 12: 10133. Published online 2022 Jun 16. doi: 10.1038/s41598-022-14305-8

PMCID:: PMC9203579

Abstract Article PDF–2.8M

Select item 85190348.

Exploring blast composition in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms: CD45RA and CD371 improve diagnostic value of flow cytometry through assessment of myeloblast heterogeneity and stem cell aberrancy

Afshin Shameli, Poonam Dharmani‐Khan, Joanne Luider, Iwona Auer, Meer‐Taher Shabani‐Rad

Cytometry B Clin Cytom. 2021 Sep; 100(5): 574–589. Published online 2020 Dec 24. doi: 10.1002/cyto.b.21983

PMCID:: PMC8519034

Abstract Article PDF–3.9M

Select item 84369249.

Identification of 4-methylation driven genes based prognostic signature in thyroid cancer: an integrative analysis based on the methylmix algorithm

Zhiwei Chen, Xiaoli Liu, Fangfang Liu, Guolie Zhang, Haijian Tu, Wei Lin, Haifeng Lin

Aging (Albany NY) 2021 Aug 31; 13(16): 20164–20178. Published online 2021 Aug 29. doi: 10.18632/aging.203338

PMCID:: PMC8436924

Abstract Article PDF–2.1M

Select item 841905010.

Aberrant activation of the CD45-Wnt signaling axis promotes stemness and therapy resistance in colorectal cancer cells

So-Yeon Park, Ji-Young Kim, Gyu-Beom Jang, Jang-Hyun Choi, Jee-Heun Kim, Choong-Jae Lee, Sunjae Lee, Jeong-Heum Baek, Kwan-Kyu Park, Jin-Man Kim, Hee Jin Chang, Nam-Chul Cho, Jeong-Seok Nam

Theranostics. 2021; 11(18): 8755–8770. Published online 2021 Aug 11. doi: 10.7150/thno.63446

PMCID:: PMC8419050

Abstract Article PDF–3.9M

Select item 838089611.

Protein tyrosine phosphatase receptor type C (PTPRC or CD45)

Maryam Ahmed Al Barashdi, Ahlam Ali, Mary Frances McMullin, Ken Mills

J Clin Pathol. 2021 Sep; 74(9): 548–552. Published online 2021 May 26. doi: 10.1136/jclinpath-2020-206927

PMCID:: PMC8380896

Abstract Article PDF–898K

Select item 822228212.

CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition

Yunmin Jung, Lai Wen, Amnon Altman, Klaus Ley

Nat Commun. 2021; 12: 3872. Published online 2021 Jun 23. doi: 10.1038/s41467-021-23792-8

PMCID:: PMC8222282

Abstract Article PDF–7.4M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 815648814.

Natural Antisense Transcript PEBP1P3 Regulates the RNA Expression, DNA Methylation and Histone Modification of CD45 Gene

Zhongjing Su, Guangyu Liu, Bin Zhang, Ze Lin, Dongyang Huang

Genes (Basel) 2021 May; 12(5): 759. Published online 2021 May 17. doi: 10.3390/genes12050759

PMCID:: PMC8156488

Abstract Article PDF–1.9M

Select item 787554215.

Immune receptor inhibition through enforced phosphatase recruitment

Ricardo A. Fernandes, Leon Su, Yoko Nishiga, Junming Ren, Aladdin M. Bhuiyan, Ning Cheng, Calvin J. Kuo, Lora K. Picton, Shozo Ohtsuki, Robbie G. Majzner, Skyler P. Rietberg, Crystal L. Mackall, Qian Yin, Lestat R. Ali, Xinbo Yang, Christina S. Savvides, Julien Sage, Michael Dougan, K. Christopher Garcia

Nature. Author manuscript; available in PMC 2021 Apr 21.

Published in final edited form as: Nature. 2020 Oct; 586(7831): 779–784. Published online 2020 Oct 21. doi: 10.1038/s41586-020-2851-2

PMCID:: PMC7875542

Abstract Article PDF–4.7M

Select item 772383316.

CD45RA, CD8β, and IFNγ Are Potential Immune Biomarkers of Human Cognitive Function

André J. Esgalhado, Débora Reste-Ferreira, Stephanie E. Albino, Adriana Sousa, Ana Paula Amaral, António Martinho, Isabel T. Oliveira, Ignacio Verde, Olga Lourenço, Ana M. Fonseca, Elsa M. Cardoso, Fernando A. Arosa

Front Immunol. 2020; 11: 592656. Published online 2020 Nov 25. doi: 10.3389/fimmu.2020.592656

PMCID:: PMC7723833

Abstract Article PDF–3.3M

Select item 768650217.

High CD45 expression of CD8+ and CD4+ T cells correlates with the size of HIV-1 reservoir in blood

Stefan Petkov, Yonas Bekele, Tadepally Lakshmikanth, Bo Hejdeman, Maurizio Zazzi, Petter Brodin, Francesca Chiodi

Sci Rep. 2020; 10: 20425. Published online 2020 Nov 24. doi: 10.1038/s41598-020-77433-z

PMCID:: PMC7686502

Abstract Article PDF–2.8M

Select item 768201818.

Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56^Lck regulates T-cell activation independently of Lck/CD45 interactions

Matthias Kästle, Camilla Merten, Roland Hartig, Thilo Kaehne, Ardiyanto Liaunardy-Jopeace, Nadine M. Woessner, Wolfgang W. Schamel, John James, Susana Minguet, Luca Simeoni, Burkhart Schraven

Cell Commun Signal. 2020; 18: 183. Published online 2020 Nov 23. doi: 10.1186/s12964-020-00673-z

PMCID:: PMC7682018

Abstract Article PDF–3.7M

Select item 764232719.

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

Dick J. H. van den Boomen, Agata Sienkiewicz, Ilana Berlin, Marlieke L. M. Jongsma, Daphne M. van Elsland, J. Paul Luzio, Jacques J. C. Neefjes, Paul J. Lehner

Nat Commun. 2020; 11: 5559. Published online 2020 Nov 3. doi: 10.1038/s41467-020-19032-0

PMCID:: PMC7642327

Abstract Article PDF–12M

Select item 758627020.

A Novel Type of Stem Cells Double-Positive for SSEA-3 and CD45 in Human Peripheral Blood

Tetsuya Sato, Shohei Wakao, Yoshihiro Kushida, Kazuki Tatsumi, Masaaki Kitada, Takatsugu Abe, Kuniyasu Niizuma, Teiji Tominaga, Shigeki Kushimoto, Mari Dezawa

Cell Transplant. 2020 Jan-Dec; 29: 0963689720923574. Published online 2020 Jun 11. doi: 10.1177/0963689720923574

PMCID:: PMC7586270

Abstract Article PDF–2.9M

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