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Select item 112318311.

STIM1-dependent store-operated calcium entry mediates sex differences in macrophage chemotaxis and monocyte recruitment

Adriana M. Fresquez, James O. Hogan, Patricia Rivera, Kristen M. Patterson, Kanakadurga Singer, Joseph M. Reynolds, Carl White

J Biol Chem. 2024 Jul; 300(7): 107422. Published online 2024 May 28. doi: 10.1016/j.jbc.2024.107422

PMCID:: PMC11231831

Abstract Article PDF–3.0M

Select item 110639342.

ORAI1 inhibition as an efficient preclinical therapy for tubular aggregate myopathy and Stormorken syndrome

Roberto Silva-Rojas, Laura Pérez-Guàrdia, Alix Simon, Sarah Djeddi, Susan Treves, Agnès Ribes, Lorenzo Silva-Hernández, Céline Tard, Jocelyn Laporte, Johann Böhm

JCI Insight. 2024 Mar 22; 9(6): e174866. Published online 2024 Mar 22. doi: 10.1172/jci.insight.174866

PMCID:: PMC11063934

Abstract Article PDF–9.1M

Select item 109779863.

The D84G mutation in STIM1 causes nuclear envelope dysfunction and myopathy in mice

Victoria Bryson, Chaojian Wang, Zirui Zhou, Kavisha Singh, Noah Volin, Eda Yildirim, Paul Rosenberg

J Clin Invest. 2024 Apr 1; 134(7): e170317. Published online 2024 Feb 1. doi: 10.1172/JCI170317

PMCID:: PMC10977986

Abstract Article PDF–4.8M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107743625.

miR-195b is required for proper cellular homeostasis in the elderly

Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco

Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8

PMCID:: PMC10774362

Abstract Article PDF–3.7M

Select item 107461446.

Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner

Yang He, Taohui Liu, Quansheng He, Wei Ke, Xiaoyu Li, Jinjin Du, Suixin Deng, Zhenfeng Shu, Jialin Wu, Baozhi Yang, Yuqing Wang, Ying Mao, Yanxia Rao, Yousheng Shu, Bo Peng

eLife. 2023; 12: RP92252. Published online 2023 Dec 22. doi: 10.7554/eLife.92252

PMCID:: PMC10746144

Abstract Article PDF–29M

Select item 107314217.

Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entry

Fan Yang, Mingyi Suo, Homayemem Weli, Mason Wong, Alex Junidi, Celeste Cummings, Ryan Johnson, Kiara Mallory, Annie Y. Liu, Zev J. Greenberg, Laura G. Schuettpelz, Mark J. Miller, Cliff J. Luke, Gwendalyn J. Randolph, Bernd H. Zinselmeyer, Juliane Bubeck Wardenburg, Regina A. Clemens

Cell Rep. Author manuscript; available in PMC 2023 Dec 20.

Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113394. Published online 2023 Nov 10. doi: 10.1016/j.celrep.2023.113394

PMCID:: PMC10731421

Abstract Article PDF–2.8M

Select item 106826448.

Loss of Ca²⁺ entry via Orai–TRPC1 induces ER stress, initiating immune activation in macrophages

Viviane Nascimento Da Conceicao, Yuyang Sun, Emily K. Zboril, Jorge J. De la Chapa, Brij B. Singh

J Cell Sci. 2020 Mar 1; 133(5): jcs237610. Published online 2019 Dec 18. doi: 10.1242/jcs.237610

PMCID:: PMC10682644

Abstract Article

Select item 106158939.

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells

Yutaro Yada, Masanori Matsumoto, Takeshi Inoue, Akemi Baba, Ryota Higuchi, Chie Kawai, Masashi Yanagisawa, Daisuke Kitamura, Shouichi Ohga, Tomohiro Kurosaki, Yoshihiro Baba

J Exp Med. 2024 Jan 1; 221(1): e20222178. Published online 2023 Oct 30. doi: 10.1084/jem.20222178

PMCID:: PMC10615893

Abstract Article PDF–5.2M

Select item 1054555710.

Stromal Interaction Molecule 1 Maintains β-Cell Identity and Function in Female Mice Through Preservation of G-Protein–Coupled Estrogen Receptor 1 Signaling

Paul Sohn, Madeline R. McLaughlin, Preethi Krishnan, Wenting Wu, Marjan Slak Rupnik, Akira Takasu, Toshiya Senda, Chih-Chun Lee, Tatsuyoshi Kono, Carmella Evans-Molina

Diabetes. 2023 Oct; 72(10): 1433–1445. Published online 2023 Jul 21. doi: 10.2337/db22-0988

PMCID:: PMC10545557

Abstract Article PDF–3.1M

Select item 1019084111.

STIM1 ablation impairs exercise-induced physiological cardiac hypertrophy and dysregulates autophagy in mouse hearts

Ingrid M. Bonilla, Stephen Baine, Anastasia Pokrass, Juan Ignacio Elio Mariángelo, Anuradha Kalyanasundaram, Vladimir Bogdanov, Louisa Mezache, Galina Sakuta, Casey M. Beard, Andriy Belevych, Svetlana Tikunova, Radmila Terentyeva, Dmitry Terentyev, Jonathan Davis, Rengasayee Veeraraghavan, Cynthia A. Carnes, Sandor Györke

J Appl Physiol (1985) 2023 May 1; 134(5): 1287–1299. Published online 2023 Mar 30. doi: 10.1152/japplphysiol.00363.2022

PMCID:: PMC10190841

Abstract Article

Select item 1003387512.

Rescue of astrocyte activity by the calcium sensor STIM1 restores long-term synaptic plasticity in female mice modelling Alzheimer’s disease

Annamaria Lia, Gabriele Sansevero, Angela Chiavegato, Miriana Sbrissa, Diana Pendin, Letizia Mariotti, Tullio Pozzan, Nicoletta Berardi, Giorgio Carmignoto, Cristina Fasolato, Micaela Zonta

Nat Commun. 2023; 14: 1590. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37240-2

PMCID:: PMC10033875

Abstract Article PDF–2.5M

Select item 1001486813.

Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice

Raed Said, Helyasadat Mortazavi, David Cooper, Katie Ovens, Ian McQuillan, Silvana Papagerakis, Petros Papagerakis

Front Physiol. 2023; 14: 1100714. Published online 2023 Mar 1. doi: 10.3389/fphys.2023.1100714

PMCID:: PMC10014868

Abstract Article PDF–3.5M

Select item 972764614.

CRISPR/SaCas9 mutagenesis of stromal interaction molecule 1 in proopiomelanocortin neurons increases glutamatergic excitability and protects against diet-induced obesity

Jian Qiu, Martha A. Bosch, Todd L. Stincic, Avery C. Hunker, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly

Mol Metab. 2022 Dec; 66: 101645. Published online 2022 Nov 25. doi: 10.1016/j.molmet.2022.101645

PMCID:: PMC9727646

Abstract Article PDF–2.3M

Select item 952891715.

STIM1-Ca²⁺ signaling in coronary sinus cardiomyocytes contributes to interatrial conduction

Hengtao Zhang, Victoria Bryson, Nancy Luo, Albert Y. Sun, Paul Rosenberg

Cell Calcium. Author manuscript; available in PMC 2022 Oct 3.

Published in final edited form as: Cell Calcium. 2020 May; 87: 102163. Published online 2020 Jan 21. doi: 10.1016/j.ceca.2020.102163

PMCID:: PMC9528917

Abstract Article PDF–2.0M

Select item 913011316.

STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet Cells

Xiaojing Liang, Jiansheng Xie, Hao Liu, Rongjie Zhao, Wei Zhang, Haidong Wang, Hongming Pan, Yubin Zhou, Weidong Han

Cell Mol Gastroenterol Hepatol. 2022; 14(1): 193–217. Published online 2022 Mar 31. doi: 10.1016/j.jcmgh.2022.03.007

PMCID:: PMC9130113

Abstract Article PDF–11M

Select item 901895517.

Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca²⁺ channel function

Serap Erdogmus, Axel R. Concepcion, Megumi Yamashita, Ikjot Sidhu, Anthony Y. Tao, Wenyi Li, Pedro P. Rocha, Bonnie Huang, Ralph Garippa, Boram Lee, Amy Lee, Johannes W. Hell, Richard S. Lewis, Murali Prakriya, Stefan Feske

Nat Commun. 2022; 13: 2033. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29725-3

PMCID:: PMC9018955

Abstract Article PDF–2.8M

Select item 901197618.

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca²⁺ entry in the immune system and beyond

Stefan Feske

Immunol Rev. Author manuscript; available in PMC 2022 Apr 15.

Published in final edited form as: Immunol Rev. 2009 Sep; 231(1): 189–209. doi: 10.1111/j.1600-065X.2009.00818.x

PMCID:: PMC9011976

Abstract Article PDF–1.3M

Select item 899140719.

The volume regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling

Axel R. Concepcion, Larry E. Wagner, II, Jingjie Zhu, Anthony Y. Tao, Jun Yang, Alireza Khodadadi-Jamayran, Yin-Hu Wang, Menghan Liu, Rebecca E. Rose, Drew R. Jones, William A. Coetzee, David I. Yule, Stefan Feske

Nat Immunol. Author manuscript; available in PMC 2022 Apr 8.

Published in final edited form as: Nat Immunol. 2022 Feb; 23(2): 287–302. Published online 2022 Feb 1. doi: 10.1038/s41590-021-01105-x

PMCID:: PMC8991407

Abstract Article PDF–6.7M

Select item 894776920.

STIM1-dependent peripheral coupling governs the contractility of vascular smooth muscle cells

Vivek Krishnan, Sher Ali, Albert L Gonzales, Pratish Thakore, Caoimhin S Griffin, Evan Yamasaki, Michael G Alvarado, Martin T Johnson, Mohamed Trebak, Scott Earley

eLife. 2022; 11: e70278. Published online 2022 Feb 11. doi: 10.7554/eLife.70278

PMCID:: PMC8947769

Abstract Article PDF–7.7M

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