PMC Links for GEO Profiles (Select 78395695) - PMC

Result Filters

Links from GEO Profiles

Items: 1 to 20 of 43

<< First< Prev

Page of 3

Select item 109097831.

Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing

Rahul Singh, Yuan Wu, Alba Herrero del Valle, Kendra E. Leigh, Sai Mong, Mark T.K. Cheng, Brian J. Ferguson, Yorgo Modis

J Biol Chem. 2024 Mar; 300(3): 105711. Published online 2024 Feb 1. doi: 10.1016/j.jbc.2024.105711

PMCID:: PMC10909783

Abstract Article PDF–8.3M

Select item 107835062.

Unraveling blunt-end RNA binding and ATPase-driven translocation activities of the RIG-I family helicase LGP2

Kuan-Ying Lee, Candice Craig, Smita S Patel

Nucleic Acids Res. 2024 Jan 11; 52(1): 355–369. Published online 2023 Nov 28. doi: 10.1093/nar/gkad1106

PMCID:: PMC10783506

Abstract Article PDF–2.7M

Select item 104696123.

High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA

Liuyiqi Jiang, Mu Xiao, Qing-Qing Liao, Luqian Zheng, Chunyan Li, Yuemei Liu, Bing Yang, Aiming Ren, Chao Jiang, Xin-Hua Feng

mSystems. 2023 Jul-Aug; 8(4): e00135-23. Published online 2023 Jun 14. doi: 10.1128/msystems.00135-23

PMCID:: PMC10469612

Abstract Article PDF–4.0M

Select item 99003464.

K63‐linked polyubiquitination of LGP2 by Riplet regulates RIG‐I‐dependent innate immune response

Takahisa Kouwaki, Tasuku Nishimura, Guanming Wang, Reiko Nakagawa, Hiroyuki Oshiumi

EMBO Rep. 2023 Feb; 24(2): e54844. Published online 2022 Dec 14. doi: 10.15252/embr.202254844

PMCID:: PMC9900346

Abstract Article PDF–1.9M

Select item 98939055.

Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population

Peng Huang, Jing-Jing Wu, Jin-Wei Zhang, Yu-Qing Hou, Ping Zhu, Rong Yin, Rong-Bin Yu, Yun Zhang, Ming Yue, Wei Hou

PeerJ. 2023; 11: e14740. Published online 2023 Jan 30. doi: 10.7717/peerj.14740

PMCID:: PMC9893905

Abstract Article PDF–9.6M

Select item 94284676.

Function conservation and disparities of zebrafish and human LGP2 genes in fish and mammalian cells responsive to poly(I:C)

Xiu-Ying Gong, Zi-Ling Qu, Yi-Lin Li, Hao-Yu Sun, Xiang Zhao, Cheng Dan, Jian-Fang Gui, Yi-Bing Zhang

Front Immunol. 2022; 13: 985792. Published online 2022 Aug 17. doi: 10.3389/fimmu.2022.985792

PMCID:: PMC9428467

Abstract Article PDF–12M

Select item 89222497.

RNA sensing via the RIG‐I‐like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency

Jorn E Stok, Timo Oosenbrug, Laurens R ter Haar, Dennis Gravekamp, Christian P Bromley, Santiago Zelenay, Caetano Reis e Sousa, Annemarthe G van der Veen

EMBO J. 2022 Mar 15; 41(6): e109760. Published online 2022 Feb 14. doi: 10.15252/embj.2021109760

PMCID:: PMC8922249

Abstract Article PDF–1.8M

Select item 81836768.

Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases

Kazuki Kato, Sadeem Ahmad, Zixiang Zhu, Janet M. Young, Xin Mu, Sehoon Park, Harmit S. Malik, Sun Hur

Mol Cell. Author manuscript; available in PMC 2021 Jun 7.

Published in final edited form as: Mol Cell. 2021 Feb 4; 81(3): 599–613.e8. Published online 2020 Dec 28. doi: 10.1016/j.molcel.2020.11.047

PMCID:: PMC8183676

Abstract Article PDF–3.6M

Select item 81038949.

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

GuanQun Liu, Jung-Hyun Lee, Zachary M. Parker, Dhiraj Acharya, Jessica J. Chiang, Michiel van Gent, William Riedl, Meredith E. Davis-Gardner, Effi Wies, Cindy Chiang, Michaela U. Gack

Nat Microbiol. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Nat Microbiol. 2021 Apr; 6(4): 467–478. Published online 2021 Mar 16. doi: 10.1038/s41564-021-00884-1

PMCID:: PMC8103894

Abstract Article PDF–3.9M

Select item 801772010.

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118

PMCID:: PMC8017720

Abstract Article PDF–1.9M

Select item 735492611.

Spatiotemporal dynamics of innate immune signaling via RIG-I–like receptors

Katharina Esser-Nobis, Lauren D. Hatfield, Michael Gale, Jr

Proc Natl Acad Sci U S A. 2020 Jul 7; 117(27): 15778–15788. Published online 2020 Jun 22. doi: 10.1073/pnas.1921861117

PMCID:: PMC7354926

Abstract Article PDF–2.7M

Select item 702664912.

LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection

Tomoko Takahashi, Yuko Nakano, Koji Onomoto, Mitsutoshi Yoneyama, Kumiko Ui-Tei

Nucleic Acids Res. 2020 Feb 20; 48(3): 1494–1507. Published online 2019 Dec 8. doi: 10.1093/nar/gkz1143

PMCID:: PMC7026649

Abstract Article PDF–3.8M

Select item 682087113.

RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination

Kendra M. Quicke, Kristin Y. Kim, Curt M. Horvath, Mehul S. Suthar

J Interferon Cytokine Res. 2019 Nov 1; 39(11): 669–683. Published online 2019 Oct 29. doi: 10.1089/jir.2019.0059

PMCID:: PMC6820871

Abstract Article PDF–1.2M

Select item 621587114.

Innate immune sensor laboratory of genetics and physiology 2 suppresses tumor cell growth and functions as a prognostic marker in neuroblastoma

Li‐Ling Lin, Chao‐Cheng Huang, Min‐Tsui Wu, Wen‐Ming Hsu, Jiin‐Haur Chuang

Cancer Sci. 2018 Nov; 109(11): 3494–3502. Published online 2018 Oct 4. doi: 10.1111/cas.13790

PMCID:: PMC6215871

Abstract Article PDF–978K

Select item 615848815.

LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs

Tomoko Takahashi, Yuko Nakano, Koji Onomoto, Fuminori Murakami, Chiaki Komori, Yutaka Suzuki, Mitsutoshi Yoneyama, Kumiko Ui-Tei

Nucleic Acids Res. 2018 Sep 28; 46(17): 9134–9147. Published online 2018 Jun 25. doi: 10.1093/nar/gky575

PMCID:: PMC6158488

Abstract Article PDF–1.3M

Select item 598975716.

RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling

Jean‐Patrick Parisien, Jessica J Lenoir, Roli Mandhana, Kenny R Rodriguez, Kenin Qian, Annie M Bruns, Curt M Horvath

EMBO Rep. 2018 Jun; 19(6): e45176. Published online 2018 Apr 16. doi: 10.15252/embr.201745176

PMCID:: PMC5989757

Abstract Article PDF–2.2M

Select item 581325917.

The RIG‐I‐like receptor LGP2 inhibits Dicer‐dependent processing of long double‐stranded RNA and blocks RNA interference in mammalian cells

Annemarthe G van der Veen, Pierre V Maillard, Jan Marten Schmidt, Sonia A Lee, Safia Deddouche‐Grass, Annabel Borg, Svend Kjær, Ambrosius P Snijders, Caetano Reis e Sousa

EMBO J. 2018 Feb 15; 37(4): e97479. Published online 2018 Jan 19. doi: 10.15252/embj.201797479