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Select item 111602571.

Heparanase and tumor invasion patterns in human oral squamous cell carcinoma xenografts

Hitoshi Kurokawa, Ken‐ichi Katsube, Katarzyna A. Podyma, Minoru Ikuta, Hachirou Iseki, Motowo Nakajima, Takumi Akashi, Ken Omura, Minoru Takagi, Masaki Yanagishita

Cancer Sci. 2003 Mar; 94(3): 277–285. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01433.x

PMCID:: PMC11160257

Abstract Article PDF–2.2M

Select item 111585532.

Heparanase gene haplotype (CGC) is associated with stage of disease in patients with ovarian carcinoma

Shirley Ralph, Paul E. C. Brenchley, Angela Summers, Daniela D. Rosa, Ric Swindell, Gordon C. Jayson

Cancer Sci. 2007 Jun; 98(6): 844–849. Published online 2007 Apr 5. doi: 10.1111/j.1349-7006.2007.00461.x

PMCID:: PMC11158553

Abstract Article PDF–150K

Select item 111582643.

Translocation of heparanase into nucleus results in cell differentiation

Tetsuji Nobuhisa, Yoshio Naomoto, Takaomi Okawa, Munenori Takaoka, Mehmet Gunduz, Takayuki Motoki, Hitoshi Nagatsuka, Hidetsugu Tsujigiwa, Yasuhiro Shirakawa, Tomoki Yamatsuji, Minoru Haisa, Junji Matsuoka, Junichi Kurebayashi, Motowo Nakajima, Shun’ichiro Taniguchi, Junji Sagara, Jian Dong, Noriaki Tanaka

Cancer Sci. 2007 Apr; 98(4): 535–540. Published online 2007 Jan 31. doi: 10.1111/j.1349-7006.2007.00420.x

PMCID:: PMC11158264

Abstract Article PDF–1.1M

Select item 111145244.

Heparanase enzyme in chronic inflammatory bowel disease and colon cancer

Esther Hermano, Immanuel Lerner, Michael Elkin

Cell Mol Life Sci. 2012 Aug; 69(15): 2501–2513. Published online 2012 Feb 14. doi: 10.1007/s00018-012-0930-8

PMCID:: PMC11114524

Abstract Article PDF–384K

Select item 108791165.

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue

Hunter A. Martinez, Ievgen Koliesnik, Gernot Kaber, Jacqueline K. Reid, Nadine Nagy, Graham Barlow, Ben A. Falk, Carlos O. Medina, Aviv Hargil, Svenja Zihsler, Israel Vlodavsky, Jin-Ping Li, Magdiel Pérez-Cruz, Sai-Wen Tang, Everett H. Meyer, Lucile E. Wrenshall, James D. Lord, K. Christopher Garcia, Theo D. Palmer, Lawrence Steinman, Gerald T. Nepom, Thomas N. Wight, Paul L. Bollyky, Hedwich F. Kuipers

Nat Commun. 2024; 15: 1564. Published online 2024 Feb 20. doi: 10.1038/s41467-024-45012-9

PMCID:: PMC10879116

Abstract Article PDF–3.7M

Select item 100477836.

Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma

Olga Ostrovsky, Katia Beider, Hila Magen, Merav Leiba, Ralph D. Sanderson, Israel Vlodavsky, Arnon Nagler

Cells. 2023 Mar; 12(6): 913. Published online 2023 Mar 16. doi: 10.3390/cells12060913

PMCID:: PMC10047783

Abstract Article PDF–1.4M

Select item 97913887.

Ethnic differences in urinary monocyte chemoattractant protein-1 and heparanase-1 levels in individuals with type 2 diabetes: the HELIUS study

Anouk I M van der Velden, Bernard M van den Berg, B J van den Born, Henrike Galenkamp, Daphne H T Ijpelaar, Ton J Rabelink

BMJ Open Diabetes Res Care. 2022; 10(6): e003003. Published online 2022 Dec 23. doi: 10.1136/bmjdrc-2022-003003

PMCID:: PMC9791388

Abstract Article PDF–417K

Select item 92792858.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 92342889.

Single-Cell Sequencing Analysis and Multiple Machine Learning Methods Identified G0S2 and HPSE as Novel Biomarkers for Abdominal Aortic Aneurysm

Tao Xiong, Xiao-Shuo Lv, Gu-Jie Wu, Yao-Xing Guo, Chang Liu, Fang-Xia Hou, Jun-Kui Wang, Yi-Fan Fu, Fu-Qiang Liu

Front Immunol. 2022; 13: 907309. Published online 2022 Jun 13. doi: 10.3389/fimmu.2022.907309

PMCID:: PMC9234288

Abstract Article PDF–16M

Select item 881008510.

Insulin-like growth factor 2 mRNA binding protein 2 regulates proliferation, migration, and angiogenesis of keratinocytes by modulating heparanase stability

Shaomin Zhi, Jun Li, Xiao Kong, Xuemei Xie, Qiangli Zhang, Guoxiang Fang

Bioengineered. 2021; 12(2): 11267–11276. Published online 2021 Dec 7. doi: 10.1080/21655979.2021.2002495

PMCID:: PMC8810085

Abstract Article PDF–1.4M

Select item 870073811.

CMV Seropositive Status Increases Heparanase SNPs Regulatory Activity, Risk of Acute GVHD and Yield of CD34⁺ Cell Mobilization

Olga Ostrovsky, Katia Beider, Yan Morgulis, Nira Bloom, Angel Cid-Arregui, Avichai Shimoni, Israel Vlodavsky, Arnon Nagler

Cells. 2021 Dec; 10(12): 3489. Published online 2021 Dec 10. doi: 10.3390/cells10123489

PMCID:: PMC8700738

Abstract Article PDF–315K

Select item 857653412.

Heparanase-Induced Activation of AKT Stabilizes β-Catenin and Modulates Wnt/β-Catenin Signaling during Herpes Simplex Virus 1 Infection

Lulia Koujah, Krishnaraju Madavaraju, Alex M. Agelidis, Chandrashekhar D. Patil, Deepak Shukla

mBio. 2021 Nov-Dec; 12(6): e02792-21. Published online 2021 Nov 9. doi: 10.1128/mBio.02792-21

PMCID:: PMC8576534

Abstract Article PDF–5.6M

Select item 854113613.

The Heparanase Regulatory Network in Health and Disease

Alyce J. Mayfosh, Tien K. Nguyen, Mark D. Hulett

Int J Mol Sci. 2021 Oct; 22(20): 11096. Published online 2021 Oct 14. doi: 10.3390/ijms222011096

PMCID:: PMC8541136

Abstract Article PDF–2.5M

Select item 840931314.

Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma

Jinchao Si, Wei Li, Xin Li, Lixing Cao, Zhiqiang Chen, Zhi Jiang

Cancer Sci. 2021 Sep; 112(9): 3491–3506. Published online 2021 Jul 8. doi: 10.1111/cas.14984

PMCID:: PMC8409313

Abstract Article PDF–3.2M

Select item 825553715.

Heparanase as a potential player in SARS-CoV-2 infection and induced coagulopathy

Safa Kinaneh, Iyad Khamaysi, Tony Karram, Shadi Hamoud

Biosci Rep. 2021 Jul 30; 41(7): BSR20210290. Published online 2021 Jul 2. doi: 10.1042/BSR20210290

PMCID:: PMC8255537

Abstract Article PDF–700K

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 805314617.

Upregulation of Fecal Epithelial Heparanase mRNA Is Associated with Increased Ulcerative Colitis Activity and Cancerization Risk

Ying Cui, Jun Zhang, Yan Chen, Le-gao Chen

Dig Dis Sci. 2021; 66(5): 1488–1498. Published online 2020 May 22. doi: 10.1007/s10620-020-06350-y

PMCID:: PMC8053146

Abstract Article PDF–1.1M

Select item 804602118.

Heparanase: A Dynamic Promoter of Myeloma Progression

Anurag Purushothaman, Ralph D. Sanderson

Adv Exp Med Biol. Author manuscript; available in PMC 2021 Apr 14.

Published in final edited form as: Adv Exp Med Biol. 2020; 1221: 331–349. doi: 10.1007/978-3-030-34521-1_12

PMCID:: PMC8046021

Abstract Article PDF–425K

Select item 771124419.

Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression

Sunil Rangarajan, Jillian R. Richter, Robert P. Richter, Shyam K. Bandari, Kaushlendra Tripathi, Israel Vlodavsky, Ralph D. Sanderson

J Histochem Cytochem. 2020 Dec; 68(12): 823–840. Published online 2020 Jul 6. doi: 10.1369/0022155420937087

PMCID:: PMC7711244

Abstract Article PDF–644K

Select item 770476220.

Significance of host heparanase in promoting tumor growth and metastasis

Gan-Lin Zhang, Lilach Gutter-Kapon, Neta Ilan, Tahira Batool, Kailash Singh, Andreas Digre, Zhengkang Luo, Stellan Sandler, Yuval Shaked, Ralph D. Sanderson, Xiao-Min Wang, Jin-Ping Li, Israel Vlodavsky

Matrix Biol. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Matrix Biol. 2020 Nov; 93: 25–42. Published online 2020 Jun 11. doi: 10.1016/j.matbio.2020.06.001

PMCID:: PMC7704762

Abstract Article PDF–1.9M

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