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Select item 111583591.

Hypoxia‐induced β‐catenin downregulation involves p53‐dependent activation of Siah‐1

Dapeng Wang, Yongxing Wang, Tao Kong, Feiyue Fan, Yongguang Jiang

Cancer Sci. 2011 Jul; 102(7): 1322–1328. Published online 2011 May 12. doi: 10.1111/j.1349-7006.2011.01950.x

PMCID:: PMC11158359

Abstract Article PDF–765K

Select item 111053182.

RIPK4 activity in keratinocytes is controlled by the SCF^β-TrCP ubiquitin ligase to maintain cortical actin organization

Giel Tanghe, Corinne Urwyler-Rösselet, Philippe De Groote, Emmanuel Dejardin, Pieter-Jan De Bock, Kris Gevaert, Peter Vandenabeele, Wim Declercq

Cell Mol Life Sci. 2018 Aug; 75(15): 2827–2841. Published online 2018 Feb 12. doi: 10.1007/s00018-018-2763-6

PMCID:: PMC11105318

Abstract Article PDF–2.2M

Select item 107897583.

The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling

Ying-Chun Shih, Hsueh-Fen Chen, Chia-Ying Wu, Yi-Ru Ciou, Chia-Wen Wang, Huai-Chia Chuang, Tse-Hua Tan

Nat Commun. 2024; 15: 532. Published online 2024 Jan 15. doi: 10.1038/s41467-024-44843-w

PMCID:: PMC10789758

Abstract Article PDF–5.3M

Select item 107754484.

Decidual stromal cells-derived exosomes incurred insufficient migration and invasion of trophoblast by disturbing of β-TrCP-mediated snail ubiquitination and degradation in unexplained recurrent spontaneous abortion

Miao Xiong, Qiaohong Wang, Xiaoxin Zhang, Liping Wen, Aimin Zhao

Eur J Med Res. 2024; 29: 39. Published online 2024 Jan 9. doi: 10.1186/s40001-023-01598-2

PMCID:: PMC10775448

Abstract Article PDF–2.9M

Select item 105658765.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103638036.

Exosomal GPT2 derived from triple‐negative breast cancer cells promotes metastasis by activating BTRC

Mingqing Cui, Jiawei Peng, Yuanyuan Zhou, Xixi Wang, Daxiang Cui

Thorac Cancer. 2023 Jul; 14(21): 2018–2025. Published online 2023 Jun 7. doi: 10.1111/1759-7714.14984

PMCID:: PMC10363803

Abstract Article PDF–7.5M

Select item 103524217.

LINC00460 Promotes Cutaneous Squamous Cell Carcinoma Progression Through Stabilizing ELAVL1 Protein

Chunli Xue, Zuxian Yang, Ben Yang, Hailin Xiong, Wei Ye

Mol Biotechnol. 2023; 65(8): 1296–1305. Published online 2022 Dec 13. doi: 10.1007/s12033-022-00631-9

PMCID:: PMC10352421

Abstract Article PDF–5.9M

Select item 103126748.

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker

Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560

Published in:: Mol Syst Biol. 2024 Apr; 20(4): 428–457.

PMCID:: PMC10312674

Abstract Article PDF–9.6M

Select item 102058589.

USP13 promotes breast cancer metastasis through FBXL14-induced Twist1 ubiquitination

Binggong Zhao, Wei Huo, Xiaomin Yu, Xiaoxia Shi, Linlin Lv, Yuxi Yang, Jie Kang, Shujing Li, Huijian Wu

Cell Oncol (Dordr) 2023; 46(3): 717–733. Published online 2023 Feb 3. doi: 10.1007/s13402-023-00779-9

PMCID:: PMC10205858

Abstract Article PDF–15M

Select item 1017409110.

Cytoplasmic YAP1‐mediated ESCRT‐III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer

Yan Guo, Yuqing Cui, Yangyang Li, Xiaoying Jin, Dandan Wang, Mengxia Lei, Fengzhi Chen, Yali Liu, Jinwen Xu, Guanyu Yao, Guangchun Zeng, Xuesong Chen

Cancer Commun (Lond) 2023 May; 43(5): 582–612. Published online 2023 Apr 2. doi: 10.1002/cac2.12417

PMCID:: PMC10174091

Abstract Article PDF–22M

Select item 1015617511.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman

Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035

Correction in:: Cell. 2023 May 25; 186(11): 2492.

PMCID:: PMC10156175

Abstract Article

Select item 1007290612.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 992963613.

HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity

Bo Yuan, Jinquan Liu, Aiping Shi, Jin Cao, Yi Yu, Yezhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi, Xiaolei Cao, Pinglong Xu, Li Shen, Tingbo Liang, Bin Zhao, Xin‐Hua Feng

EMBO J. 2023 Feb; 42(4): e111549. Published online 2023 Jan 4. doi: 10.15252/embj.2022111549

PMCID:: PMC9929636

Abstract Article PDF–7.0M

Select item 992674314.

Extracellular matrix stiffness regulates degradation of MST2 via SCF ^βTrCP

Ana Paula Zen Petisco Fiore, Ana Maria Rodrigues, Helder Veras Ribeiro-Filho, Antonio Carlos Manucci, Pedro de Freitas Ribeiro, Mayara Carolinne Silva Botelho, Christine Vogel, Paulo Sergio Lopes-de-Oliveira, Michele Pagano, Alexandre Bruni-Cardoso

Biochim Biophys Acta Gen Subj. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Biochim Biophys Acta Gen Subj. 2022 Dec; 1866(12): 130238. Published online 2022 Aug 28. doi: 10.1016/j.bbagen.2022.130238

PMCID:: PMC9926743

Abstract Article PDF–1.0M

Select item 990801115.

A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

Christopher Nardone, Brad A. Palanski, Daniel C. Scott, Richard T. Timms, Karl W. Barber, Xin Gu, Aoyue Mao, Yumei Leng, Emma V. Watson, Brenda A. Schulman, Philip A. Cole, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2023 Feb 14.

Published in final edited form as: Mol Cell. 2023 Jan 5; 83(1): 57–73.e9. doi: 10.1016/j.molcel.2022.12.013

PMCID:: PMC9908011

Abstract Article PDF–2.9M

Select item 980764716.

AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer

Yongming Fu, Tuoyu Cao, Xiaorui Zou, Yubing Ye, Youhong Liu, Yuchong Peng, Tanggang Deng, Linglong Yin, Xiong Li

Oncogenesis. 2023 Dec; 12(1): 1. Published online 2023 Jan 2. doi: 10.1038/s41389-022-00446-y

PMCID:: PMC9807647

Abstract Article PDF–4.6M

Select item 979524817.

Pan-cancer analysis of FBXW family with potential implications in prognosis and immune infiltration

Tingting Huang, XIaoxiao OuYang, Jiwei Li, Bingbing Shi, Zhengda Shan, Zhiyuan Shi, Zhangru Yang

Front Immunol. 2022; 13: 1084339. Published online 2022 Dec 14. doi: 10.3389/fimmu.2022.1084339

PMCID:: PMC9795248

Abstract Article PDF–7.5M

Select item 971352118.

FRK inhibits glioblastoma progression via phosphorylating YAP and inducing its ubiquitylation and degradation by Siah1

Yan Wang, Kai Wang, Jiale Fu, Yu Zhang, Yufei Mao, Xu Wang, Xiang Wang, Rutong Yu, Xiuping Zhou

Neuro Oncol. 2022 Dec; 24(12): 2107–2120. Published online 2022 Jun 20. doi: 10.1093/neuonc/noac156

PMCID:: PMC9713521

Abstract Article PDF–51M

Select item 969136919.

circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR

Fengzhi Ding, Lin Lu, Chengjie Wu, Xiangbin Pan, Bin Liu, Yu Zhang, Yanli Wang, Weiliang Wu, Bing Yan, Yuqing Zhang, Xi-Yong Yu, Yangxin Li

Theranostics. 2022; 12(17): 7550–7566. Published online 2022 Oct 31. doi: 10.7150/thno.77630

PMCID:: PMC9691369

Abstract Article PDF–2.7M

Select item 966281720.

Regulated degradation of the inner nuclear membrane protein SUN2 maintains nuclear envelope architecture and function

Logesvaran Krshnan, Wingyan Skyla Siu, Michael Van de Weijer, Daniel Hayward, Elena Navarro Guerrero, Ulrike Gruneberg, Pedro Carvalho

eLife. 2022; 11: e81573. Published online 2022 Nov 1. doi: 10.7554/eLife.81573

PMCID:: PMC9662817

Abstract Article PDF–3.9M

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