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Items: 1 to 20 of 75

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
4.
PCAT19 Regulates the Proliferation and Apoptosis of Lung Cancer Cells by Inhibiting miR-25-3p via Targeting the MAP2K4 Signal Axis
Bing Wang, Shengrong Yang, Yang Jia, Jianru Yang, Kun Du, Yujie Luo, Yunhe Li, Zhenghong Wang, Yi Liu, Bing Zhu
Dis Markers. 2022; 2022: 2442094. Published online 2022 May 16. doi: 10.1155/2022/2442094
PMCID:
PMC9126706
AbstractArticlePDF–3.6M
5.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
6.
FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury
Bohm Lee, Yeonsoo Oh, Eunhye Cho, Aaron DiAntonio, Valeria Cavalli, Jung Eun Shin, Hae Woong Choi, Yongcheol Cho
J Biol Chem. 2022 Mar; 298(3): 101647. Published online 2022 Jan 29. doi: 10.1016/j.jbc.2022.101647
PMCID:
PMC8881485
AbstractArticlePDF–3.6M
7.
Enthalpy–Entropy Compensation in the Promiscuous Interaction of an Intrinsically Disordered Protein with Homologous Protein Partners
Jaka Kragelj, Thibault Orand, Elise Delaforge, Laura Tengo, Martin Blackledge, Andrés Palencia, Malene Ringkjøbing Jensen
Biomolecules. 2021 Aug; 11(8): 1204. Published online 2021 Aug 13. doi: 10.3390/biom11081204
PMCID:
PMC8391806
AbstractArticlePDF–3.3M
8.
N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease
Tomas Koudelka, Juliane Boger, Alessandra Henkel, Robert Schönherr, Stefanie Krantz, Sabine Fuchs, Estefanía Rodríguez, Lars Redecke, Andreas Tholey
Proteomics. 2021 Jan; 21(2): 2000246. Published online 2020 Nov 17. doi: 10.1002/pmic.202000246
PMCID:
PMC7645863
AbstractArticlePDF–497K
9.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
10.
SH3RF3 promotes breast cancer stem-like properties via JNK activation and PTX3 upregulation
Peiyuan Zhang, Yingjie Liu, Cheng Lian, Xuan Cao, Yuan Wang, Xiaoxun Li, Min Cong, Pu Tian, Xue Zhang, Gang Wei, Tong Liu, Guohong Hu
Nat Commun. 2020; 11: 2487. Published online 2020 May 19. doi: 10.1038/s41467-020-16051-9
PMCID:
PMC7237486
AbstractArticlePDF–1.7M
11.
Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
Xueran Chen, Aijun Hao, Xian Li, Kaiqin Ye, Chenggang Zhao, Haoran Yang, Huihui Ma, Lei Hu, Zhiyang Zhao, Lizhu Hu, Fang Ye, Qiuyan Sun, Huaman Zhang, Hongzhi Wang, Xuebiao Yao, Zhiyou Fang
Theranostics. 2020; 10(3): 998–1015. Published online 2020 Jan 1. doi: 10.7150/thno.40076
PMCID:
PMC6956818
AbstractArticlePDF–3.7M
12.
MAP2K4 interacts with Vimentin to activate the PI3K/AKT pathway and promotes breast cancer pathogenesis
Shu Liu, Juan Huang, Yewei Zhang, Yiyi Liu, Shi Zuo, Rong Li
Aging (Albany NY) 2019 Nov 30; 11(22): 10697–10710. Published online 2019 Nov 25. doi: 10.18632/aging.102485
PMCID:
PMC6914392
AbstractArticlePDF–1.9M
13.
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway
Yiyi Liu, Qingping Jiang, Xiong Liu, Xian Lin, ZiBo Tang, Chen Liu, Jin Zhou, Mengyang Zhao, Xin Li, Zhao Cheng, Libo Li, Yingying Xie, Zhen Liu, Weiyi Fang
EBioMedicine. 2019 Oct; 48: 386–404. Published online 2019 Oct 5. doi: 10.1016/j.ebiom.2019.08.040
PMCID:
PMC6838365
AbstractArticlePDF–5.5M
14.
PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling
Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin
Cell Rep. Author manuscript; available in PMC 2019 Jun 26.
Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060
PMCID:
PMC6594551
AbstractArticlePDF–1.4M
15.
Orange is the new black: Kinases are the new master regulators of tumor suppression
Elvira An, John Brognard
IUBMB Life. 2019 Jun; 71(6): 738–748. Published online 2018 Dec 11. doi: 10.1002/iub.1981
PMCID:
PMC6563145
AbstractArticlePDF–1.2M
16.
MicroRNA‐802 plays a tumour suppressive role in tongue squamous cell carcinoma through directly targeting MAP2K4
Xiaozhen Wu, Zuode Gong, Lanying Sun, Long Ma, Qibao Wang
Cell Prolif. 2017 Jun; 50(3): e12336. Published online 2017 Mar 20. doi: 10.1111/cpr.12336
PMCID:
PMC6529076
AbstractArticlePDF–901K
17.
Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers
Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, Zhanfang Guo, Jeremy Hoog, Petra Erdmann-Gilmore, Tina Primeau, Shixia Huang, Dean P. Edwards, Xiaowei Wang, Xuya Wang, Emily Kawaler, D R. Mani, Karl R. Clauser, Feng Gao, Jingqin Luo, Sherri R. Davies, Gary L. Johnson, Kuan-lin Huang, Christopher J. Yoon, Li Ding, David Fenyö, Matthew J. Ellis, R. Reid Townsend, Jason M. Held, Steven A. Carr, Cynthia X. Ma
Cancer Res. Author manuscript; available in PMC 2019 May 15.
Published in final edited form as: Cancer Res. 2018 May 15; 78(10): 2732–2746. Published online 2018 Feb 22. doi: 10.1158/0008-5472.CAN-17-1990
PMCID:
PMC5955814
AbstractArticlePDF–1.2M
18.
MicroRNA-145 attenuates TNF-α-driven cartilage matrix degradation in osteoarthritis via direct suppression of MKK4
Guoli Hu, Xiaoying Zhao, Chuandong Wang, Yiyun Geng, Jingyu Zhao, Jiajia Xu, Bin Zuo, Chen Zhao, Chenglong Wang, Xiaoling Zhang
Cell Death Dis. 2017 Oct; 8(10): e3140. Published online 2017 Oct 26. doi: 10.1038/cddis.2017.522
PMCID:
PMC5682684
AbstractArticlePDF–6.1M
19.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
20.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M

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