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Items: 1 to 20 of 186

1.
BCL2L2 is a probable target for novel 14q11.2 amplification detected in a non‐small cell lung cancer cell line
Tsutomu Kawasaki, Sana Yokoi, Hitoshi Tsuda, Hiroyuki Izumi, Ken‐ichi Kozaki, Shinsuke Aida, Yuichi Ozeki, Yasuyuki Yoshizawa, Issei Imoto, Johji Inazawa
Cancer Sci. 2007 Jul; 98(7): 1070–1077. Published online 2007 Apr 24. doi: 10.1111/j.1349-7006.2007.00491.x
PMCID:
PMC11159300
AbstractArticlePDF–326K
2.
Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord
Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537
PMCID:
PMC10850818
AbstractArticlePDF–2.7M
3.
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6
PMCID:
PMC10764958
AbstractArticlePDF–4.4M
4.
MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2
Jun Deng, Kangwen Ning, Danhong Liu, Dahua Wu, Rongwen Wan, Jinwen Ge
Neuroreport. 2023 Jan 14; 34(1): 38–45. Published online 2022 Nov 23. doi: 10.1097/WNR.0000000000001856
PMCID:
PMC10519296
AbstractArticlePDF–649K
5.
BCL-W makes only minor contributions to MYC-driven lymphoma development
Sarah T. Diepstraten, John E. La Marca, Catherine Chang, Savannah Young, Andreas Strasser, Gemma L. Kelly
Oncogene. 2023; 42(37): 2776–2781. Published online 2023 Aug 11. doi: 10.1038/s41388-023-02804-5
PMCID:
PMC10491490
AbstractArticlePDF–1.5M
6.
PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation
Wen-Liang Guan, Lei-Lei Jiang, Xiao-Fang Yin, Hong-Yu Hu
J Biol Chem. 2023 Aug; 299(8): 105019. Published online 2023 Jul 7. doi: 10.1016/j.jbc.2023.105019
PMCID:
PMC10403730
AbstractArticlePDF–4.6M
7.
The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
Katharina Kases, Erik Schubert, Zamaneh Hajikhezri, Mårten Larsson, Priya Devi, Mahmoud Darweesh, Leif Andersson, Göran Akusjärvi, Tanel Punga, Shady Younis
J Biol Chem. 2023 Aug; 299(8): 104959. Published online 2023 Jun 23. doi: 10.1016/j.jbc.2023.104959
PMCID:
PMC10371797
AbstractArticlePDF–3.6M
8.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
9.
PABPN1 prevents the nuclear export of an unspliced RNA with a constitutive transport element and controls human gene expression via intron retention
Lauren Kwiatek, Anne-Marie Landry-Voyer, Mélodie Latour, Carlo Yague-Sanz, Francois Bachand
RNA. 2023 May; 29(5): 644–662. doi: 10.1261/rna.079294.122
PMCID:
PMC10158996
AbstractArticlePDF–8.5M
10.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
11.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
12.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
13.
Assessment of PABPN1 nuclear inclusions on a large cohort of patients and in a human xenograft model of oculopharyngeal muscular dystrophy
Fanny Roth, Jamila Dhiab, Alexis Boulinguiez, Hadidja-Rose Mouigni, Saskia Lassche, Elisa Negroni, Laura Muraine, Alix Marhic, Alison Oliver, Jeanne Lainé, Andrée Rouche, Erin K. O’Ferrall, Baziel van Engelen, Coen Ottenheijm, Hagar Greif, Sergiu Blumen, Jean Lacau St Guily, Sophie Perie, Gillian Butler-Browne, Vincent Mouly, Capucine Trollet
Acta Neuropathol. 2022; 144(6): 1157–1170. Published online 2022 Oct 5. doi: 10.1007/s00401-022-02503-7
PMCID:
PMC9637588
AbstractArticlePDF–3.0M
14.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M
15.
The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2
Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue
Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600
PMCID:
PMC9475453
AbstractArticlePDF–4.4M
16.
Novel read‐through fusion transcript Bcl2l2‐Pabpn1 in glioblastoma cells
Lin Zhang, Dan Wang, Xiao Han, Xiaoxiao Guo, Yuanyuan Cao, Ying Xia, Dianshuai Gao
J Cell Mol Med. 2022 Sep; 26(17): 4686–4697. Published online 2022 Jul 27. doi: 10.1111/jcmm.17481
PMCID:
PMC9443946
AbstractArticlePDF–11M
17.
The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis
Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi
Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y
PMCID:
PMC9343455
AbstractArticlePDF–3.7M
18.
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7
PMCID:
PMC9290241
AbstractArticlePDF–8.2M
19.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
20.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M

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