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Items: 1 to 20 of 140

1.
Deubiquitination of CIB1 by USP14 promotes lenvatinib resistance via the PAK1-ERK1/2 axis in hepatocellular carcinoma
Ming-Hao Xu, Yi-Min Zheng, Bu-Gang Liang, Wen-Xin Xu, Jun Cao, Pei Wang, Zi-Ying Dong, Chen-Hao Zhou, Hui-Chuan Sun, Ning Ren, Ai-Wu Ke, Ying-Hao Shen
Int J Biol Sci. 2024; 20(9): 3269–3284. Published online 2024 Jun 3. doi: 10.7150/ijbs.96031
PMCID:
PMC11234209
AbstractArticlePDF–9.9M
2.
Structural Dynamics Analysis of USP14 Activation by AKT-Mediated Phosphorylation
Raju Dash, Non-Nuoc Tran, Sung Bae Lee, Byung-Hoon Lee
Cells. 2024 Jun; 13(11): 955. Published online 2024 May 31. doi: 10.3390/cells13110955
PMCID:
PMC11171753
AbstractArticlePDF–18M
3.
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4
Yuting Chen, Yuanyuan Feng, Yanling Lin, Xiaohan Zhou, Lingzhi Wang, Yingtong Zhou, Kefan Lin, Longmei Cai
Br J Cancer. 2024 Mar 23; 130(5): 755–768. Published online 2024 Jan 16. doi: 10.1038/s41416-024-02574-1
PMCID:
PMC10912431
AbstractArticlePDF–12M
4.
Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinoma
Xingming Zhang, Lou Geng, Yi Tang, Yingying Wang, Youping Zhang, Chujiao Zhu, Hu Lei, Hanzhang Xu, Qi Zhu, Yingli Wu, Wenli Gu
J Transl Med. 2024; 22: 193. Published online 2024 Feb 22. doi: 10.1186/s12967-024-04943-z
PMCID:
PMC10885370
AbstractArticlePDF–11M
5.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
6.
USP14 governs CYP2E1 to promote nonalcoholic fatty liver disease through deubiquitination and stabilization of HSP90AA1
Dongqin Wei, Xin Tian, Longbo Zhu, Han Wang, Chao Sun
Cell Death Dis. 2023 Aug; 14(8): 566. Published online 2023 Aug 26. doi: 10.1038/s41419-023-06091-6
PMCID:
PMC10460448
AbstractArticlePDF–15M
7.
SDC2 Stabilization by USP14 Promotes Gastric Cancer Progression through Co-option of PDK1
Li You, Yi Dou, Yu Zhang, Hongwei Xiao, Hong Lv, Gong-Hong Wei, Dazhi Xu
Int J Biol Sci. 2023; 19(11): 3483–3498. Published online 2023 Jul 9. doi: 10.7150/ijbs.84331
PMCID:
PMC10367555
AbstractArticlePDF–10M
8.
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
Alexis González, Adriana Covarrubias-Pinto, Ramachandra M. Bhaskara, Marius Glogger, Santosh K. Kuncha, Audrey Xavier, Eric Seemann, Mohit Misra, Marina E. Hoffmann, Bastian Bräuning, Ashwin Balakrishnan, Britta Qualmann, Volker Dötsch, Brenda A. Schulman, Michael M. Kessels, Christian A. Hübner, Mike Heilemann, Gerhard Hummer, Ivan Dikić
Nature. 2023; 618(7964): 394–401. Published online 2023 May 24. doi: 10.1038/s41586-023-06089-2
PMCID:
PMC10247366
AbstractArticlePDF–24M
9.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
10.
FAT10 and NUB1L cooperate to activate the 26S proteasome
Florian Brockmann, Nicola Catone, Christine Wünsch, Fabian Offensperger, Martin Scheffner, Gunter Schmidtke, Annette Aichem
Life Sci Alliance. 2023 Aug; 6(8): e202201463. Published online 2023 May 15. doi: 10.26508/lsa.202201463
PMCID:
PMC10185811
AbstractArticlePDF–2.5M
11.
Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC)
Ethan L. Morgan, Tiffany Toni, Ramya Viswanathan, Yvette Robbins, Xinping Yang, Hui Cheng, Sreenivasulu Gunti, Angel Huynh, Anastasia L. Sowers, James B. Mitchell, Clint T. Allen, Zhong Chen, Carter Van Waes
Cell Death Differ. 2023 May; 30(5): 1382–1396. Published online 2023 Apr 13. doi: 10.1038/s41418-023-01144-x
PMCID:
PMC10154301
AbstractArticlePDF–7.0M
12.
Ceramide Synthase 1 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Interacting with USP14 and Downregulating the PI3K/AKT/mTOR Signaling Pathway
Yiquan Xu, Junfan Pan, Ying Lin, Yun Wu, Yusheng Chen, Hongru Li
Cancers (Basel) 2023 Apr; 15(7): 1994. Published online 2023 Mar 27. doi: 10.3390/cancers15071994
PMCID:
PMC10093008
AbstractArticlePDF–37M
13.
RGS2 promotes estradiol biosynthesis by trophoblasts during human pregnancy
Chao Tang, Meiyuan Jin, Bingbing Ma, Bin Cao, Chao Lin, Shouying Xu, Jiayong Li, Qiang Xu
Exp Mol Med. 2023 Jan; 55(1): 240–252. Published online 2023 Jan 18. doi: 10.1038/s12276-023-00927-z
PMCID:
PMC9898290
AbstractArticlePDF–4.4M
14.
A self-amplifying USP14-TAZ loop drives the progression and liver metastasis of pancreatic ductal adenocarcinoma
Chunle Zhao, Jun Gong, Yu Bai, Taoyuan Yin, Min Zhou, Shutao Pan, Yuhui Liu, Yang Gao, Zhenxiong Zhang, Yongkang Shi, Feng Zhu, Hang Zhang, Min Wang, Renyi Qin
Cell Death Differ. 2023 Jan; 30(1): 1–15. Published online 2022 Jul 29. doi: 10.1038/s41418-022-01040-w
PMCID:
PMC9883464
AbstractArticlePDF–9.7M
15.
USP14 promotes colorectal cancer progression by targeting JNK for stabilization
Xue-Hua Du, Shao-Bo Ke, Xin-Yi Liang, Jie Gao, Xiao-Xiao Xie, Lin-Zhi Qi, Xue-Yi Liu, Guo-Yuan Xu, Xiao-Dong Zhang, Run-Lei Du, Shang-Ze Li
Cell Death Dis. 2023 Jan; 14(1): 56. Published online 2023 Jan 24. doi: 10.1038/s41419-023-05579-5
PMCID:
PMC9873792
AbstractArticlePDF–4.7M
16.
USP14 promotes pyroptosis of human annulus fibrosus cells derived from patients with intervertebral disc degeneration through deubiquitination of NLRP3: USP14 induces deubiquitination of NLRP3
Bao Hai, Tianli Mao, Chuanchao Du, Fei Jia, Yu Liu, Qingpeng Song, Xiaoyu Pan, Xiaoguang Liu, Bin Zhu
Acta Biochim Biophys Sin (Shanghai) 2022 Nov; 54(11): 1720–1730. Published online 2022 Nov 16. doi: 10.3724/abbs.2022171
PMCID:
PMC9828310
AbstractArticlePDF–1.5M
17.
USP14 regulates cell cycle progression through deubiquitinating CDK1 in breast cancer: USP14 deubiquitinates CDK1 in breast cancer
Yuhan Liu, Jing Xu, Yanan Wang, Mingxi Gan, Qifan Hu, Jianbin Wang, Tianyu Han
Acta Biochim Biophys Sin (Shanghai) 2022 Nov; 54(11): 1610–1618. Published online 2022 Nov 8. doi: 10.3724/abbs.2022160
PMCID:
PMC9827946
AbstractArticlePDF–1.5M
18.
MFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells
Yanan Cui, Lijuan Luo, Zihang Zeng, Xiangming Liu, Tiao Li, Xue He, Yiming Ma, Weiwei Meng, Huihui Zeng, Yingjiao Long, Dandan Zong, Yan Chen
Cell Death Dis. 2023 Jan; 14(1): 2. Published online 2023 Jan 3. doi: 10.1038/s41419-022-05455-8
PMCID:
PMC9810602
AbstractArticlePDF–7.2M
19.
Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer
Yingjie Su, Kai Zeng, Shuchang Liu, Yi Wu, Chunyu Wang, Shengli Wang, Lin Lin, Renlong Zou, Ge Sun, Ruina Luan, Baosheng Zhou, Yu Bai, Jumin Niu, Yi Zhang, Yue Zhao
J Biol Chem. 2023 Jan; 299(1): 102734. Published online 2022 Nov 22. doi: 10.1016/j.jbc.2022.102734
PMCID:
PMC9800553
AbstractArticlePDF–3.8M
20.
PSMC3 promotes RNAi by maintaining AGO2 stability through USP14
Yan Jia, Jianing Zhao, Tao Yu, Xue Zhang, Xiaozhen Qi, Tongxin Hao, Zeyuan Jin, Xiaoqing Zhao
Cell Mol Biol Lett. 2022; 27: 111. Published online 2022 Dec 17. doi: 10.1186/s11658-022-00411-y
PMCID:
PMC9759854
AbstractArticlePDF–3.1M

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