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Select item 113945371.

The Role of αvβ3 Integrin in Lamina Cribrosa Cell Mechanotransduction in Glaucoma

Mustapha Irnaten, Ellen Gaynor, Colm O’Brien

Cells. 2024 Sep; 13(17): 1487. Published online 2024 Sep 5. doi: 10.3390/cells13171487

PMCID:: PMC11394537

Abstract Article PDF–2.1M

Select item 112852322.

IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma

Marta Lopez-Cerda, Laura Lorenzo-Sanz, Victoria da Silva-Diz, Sandra Llop, Rosa M. Penin, Josep Oriol Bermejo, Richard de Goeij-de Haas, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Juan Martin-Liberal, Purificación Muñoz

J Exp Clin Cancer Res. 2024; 43: 211. Published online 2024 Jul 29. doi: 10.1186/s13046-024-03119-3

PMCID:: PMC11285232

Abstract Article PDF–18M

Select item 111597373.

Significance of integrin αvβ5 and erbB3 in enhanced cell migration and liver metastasis of colon carcinomas stimulated by hepatocyte‐derived heregulin

Toshiaki Yoshioka, Yuji Nishikawa, Reiko Ito, Makiko Kawamata, Yuko Doi, Yohei Yamamoto, Masayuki Yoshida, Yasufumi Omori, Hitoshi Kotanagi, Takashi Masuko, Katsuhiko Enomoto

Cancer Sci. 2010 Sep; 101(9): 2011–2018. Published online 2010 Jun 9. doi: 10.1111/j.1349-7006.2010.01640.x

PMCID:: PMC11159737

Abstract Article PDF–704K

Select item 111146674.

The cross-talk between the urokinase receptor and fMLP receptors regulates the activity of the CXCR4 chemokine receptor

Nunzia Montuori, Katia Bifulco, Maria Vincenza Carriero, Claudio La Penna, Valeria Visconte, Daniela Alfano, Ada Pesapane, Francesca Wanda Rossi, Salvatore Salzano, Guido Rossi, Pia Ragno

Cell Mol Life Sci. 2011 Jul; 68(14): 2453–2467. Published online 2010 Oct 24. doi: 10.1007/s00018-010-0564-7

PMCID:: PMC11114667

Abstract Article PDF–728K

Select item 111053775.

D2A sequence of the urokinase receptor induces cell growth through αvβ3 integrin and EGFR

Gabriele Eden, Marco Archinti, Ralitsa Arnaudova, Giuseppina Andreotti, Andrea Motta, Federico Furlan, Valentina Citro, Maria Vittoria Cubellis, Bernard Degryse

Cell Mol Life Sci. 2018 May; 75(10): 1889–1907. Published online 2017 Nov 28. doi: 10.1007/s00018-017-2718-3

PMCID:: PMC11105377

Abstract Article PDF–2.4M

Select item 110960686.

Integrin αvβ3 upregulation in response to nutrient stress promotes lung cancer cell metabolic plasticity

Arin Nam, Shashi Jain, Chengsheng Wu, Alejandro Campos, Ryan M. Shepard, Ziqi Yu, Joshua P. Reddy, Tami Von Schalscha, Sara M. Weis, Mark Onaitis, Hiromi I. Wettersten, David A. Cheresh

Cancer Res. Author manuscript; available in PMC 2024 Nov 15.

Published in final edited form as: Cancer Res. 2024 May 15; 84(10): 1630–1642. doi: 10.1158/0008-5472.CAN-23-2700

PMCID:: PMC11096068

Abstract Article PDF–2.4M

Select item 109646837.

A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection

Mingming Xue, Lingyu Xing, Yilin Yang, Mian Shao, Fengqing Liao, Feixiang Xu, Yumei Chen, Sheng Wang, Bin Chen, Chenling Yao, Guorong Gu, Chaoyang Tong

BMC Cardiovasc Disord. 2024; 24: 180. Published online 2024 Mar 26. doi: 10.1186/s12872-024-03778-2

PMCID:: PMC10964683

Abstract Article PDF–4.4M

Select item 109168668.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 108854389.

Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway

Hao Wang, Yin-hai Xu, Yi Guo

J Ovarian Res. 2024; 17: 50. Published online 2024 Feb 23. doi: 10.1186/s13048-024-01377-5

PMCID:: PMC10885438

Abstract Article PDF–20M

Select item 1070227310.

Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance

William Echavidre, Jérôme Durivault, Célia Gotorbe, Thays Blanchard, Marina Pagnuzzi, Valérie Vial, Florian Raes, Alexis Broisat, Rémy Villeneuve, Régis Amblard, Nicolas Garnier, Cécile Ortholan, Marc Faraggi, Benjamin Serrano, Vincent Picco, Christopher Montemagno

Cancer Res Commun. 2023 Dec; 3(12): 2483–2496. Published online 2023 Dec 7. doi: 10.1158/2767-9764.CRC-23-0298

PMCID:: PMC10702273

Abstract Article PDF–16M

Select item 1065177311.

Integrin αvβ1 facilitates ACE2-mediated entry of SARS-CoV-2

Zeqiong Cai, Han Bai, Doudou Ren, Biyun Xue, Yijia Liu, Tian Gong, Xuan Zhang, Peng Zhang, Junsheng Zhu, Binyin Shi, Chengsheng Zhang

Virus Res. 2024 Jan 2; 339: 199251. Published online 2023 Nov 2. doi: 10.1016/j.virusres.2023.199251

PMCID:: PMC10651773

Abstract Article PDF–4.0M

Select item 1061438012.

Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress

Yan Peng, Rongmei Qu, Yuchao Yang, Tingyu Fan, Bing Sun, Asmat Ullah Khan, Shutong Wu, Wenqing Liu, Jinhui Zhu, Junxin Chen, Xiaoqing Li, Jingxing Dai, Jun Ouyang

Cell Commun Signal. 2023; 21: 308. Published online 2023 Oct 30. doi: 10.1186/s12964-022-01027-7

PMCID:: PMC10614380

Abstract Article PDF–12M

Select item 1034596313.

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy

Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald

Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535

PMCID:: PMC10345963

Abstract Article PDF–13M

Select item 1024444514.

Molecular basis for the recognition of 24-(S)-hydroxycholesterol by integrin αvβ3

Jeevan B. Gc, Justin Chen, Swechha M. Pokharel, Indira Mohanty, Charles Mariasoosai, Peter Obi, Paul Panipinto, Smarajit Bandyopadhyay, Santanu Bose, Senthil Natesan

Sci Rep. 2023; 13: 9166. Published online 2023 Jun 6. doi: 10.1038/s41598-023-36040-4

PMCID:: PMC10244445

Abstract Article PDF–2.6M

Select item 1023742215.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1013074816.

The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand

Yoko K Takada, Scott I Simon, Yoshikazu Takada

Life Sci Alliance. 2023 Jul; 6(7): e202201747. Published online 2023 Apr 25. doi: 10.26508/lsa.202201747

PMCID:: PMC10130748

Abstract Article PDF–3.6M

Select item 997119517.

CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway

Guojie Xu, Lei Zhao, Qingling Hua, Lanqing Wang, Hongli Liu, Zhenyu Lin, Min Jin, Jing Wang, Pengfei Zhou, Kunyu Yang, Gang Wu, Dandan Yu, Dejun Zhang, Tao Zhang

Cell Death Dis. 2023 Feb; 14(2): 167. Published online 2023 Feb 27. doi: 10.1038/s41419-023-05644-z

PMCID:: PMC9971195

Abstract Article PDF–15M

Select item 996289418.

The D405N Mutation in the Spike Protein of SARS-CoV-2 Omicron BA.5 Inhibits Spike/Integrins Interaction and Viral Infection of Human Lung Microvascular Endothelial Cells

Antonella Bugatti, Federica Filippini, Serena Messali, Marta Giovanetti, Cosetta Ravelli, Alberto Zani, Massimo Ciccozzi, Arnaldo Caruso, Francesca Caccuri

Viruses. 2023 Feb; 15(2): 332. Published online 2023 Jan 24. doi: 10.3390/v15020332

PMCID:: PMC9962894

Abstract Article PDF–2.4M

Select item 977255819.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 964166520.

Dysregulation of integrin αvβ3 and α5β1 impedes migration of placental endothelial cells in fetal growth restriction

Diane L. Gumina, Shuhan Ji, Amanda Flockton, Kathryn McPeak, Dominik Stich, Radu Moldovan, Emily J. Su

Development. 2022 Oct 1; 149(19): dev200717. Published online 2022 Oct 4. doi: 10.1242/dev.200717

PMCID:: PMC9641665

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