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Select item 111051911.

The HMG box transcription factor HBP1: a cell cycle inhibitor at the crossroads of cancer signaling pathways

Emeline Bollaert, Audrey de Rocca Serra, Jean-Baptiste Demoulin

Cell Mol Life Sci. 2019 Apr; 76(8): 1529–1539. Published online 2019 Jan 25. doi: 10.1007/s00018-019-03012-9

PMCID:: PMC11105191

Abstract Article PDF–2.7M

Select item 101516152.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 85672383.

The human GID complex engages two independent modules for substrate recruitment

Weaam I Mohamed, Sophia L Park, Julius Rabl, Alexander Leitner, Daniel Boehringer, Matthias Peter

EMBO Rep. 2021 Nov 4; 22(11): e52981. Published online 2021 Oct 14. doi: 10.15252/embr.202152981

PMCID:: PMC8567238

Abstract Article PDF–2.1M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77508965.

miR-146b Functions as an Oncogene in Oral Squamous Cell Carcinoma by Targeting HBP1

Kui Li, Zheng Zhou, Ju Li, Rui Xiang

Technol Cancer Res Treat. 2020; 19: 1533033820959404. Published online 2020 Dec 17. doi: 10.1177/1533033820959404

PMCID:: PMC7750896

Abstract Article PDF–2.0M

Select item 67560506.

MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1

Zhengyi Cao, Junhui Xue, Yuning Cheng, Jiyin Wang, Yujuan Liu, Hui Li, Wei Jiang, Gang Li, Yaoting Gui, Xiaowei Zhang

Oncogene. 2019; 38(24): 4835–4855. Published online 2019 Feb 28. doi: 10.1038/s41388-019-0761-2

PMCID:: PMC6756050

Abstract Article PDF–6.2M

Select item 67134757.

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance

Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman

eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362

PMCID:: PMC6713475

Abstract Article PDF–4.6M

Select item 66098018.

Long noncoding RNA actin filament‐associated protein 1 antisense RNA 1 promotes malignant phenotype through binding with lysine‐specific demethylase 1 and repressing HMG box‐containing protein 1 in non‐small‐cell lung cancer

Shanxun Yu, Daolu Yang, Yunyao Ye, Pei Liu, Zhenyao Chen, Tianyao Lei, Jiaze Pu, Longfa Liu, Zhaoxia Wang

Cancer Sci. 2019 Jul; 110(7): 2211–2225. Published online 2019 May 29. doi: 10.1111/cas.14039

PMCID:: PMC6609801

Abstract Article PDF–2.8M

Select item 60374779.

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation

Fabienne Lampert, Diana Stafa, Algera Goga, Martin Varis Soste, Samuel Gilberto, Natacha Olieric, Paola Picotti, Markus Stoffel, Matthias Peter

eLife. 2018; 7: e35528. Published online 2018 Jun 18. doi: 10.7554/eLife.35528

PMCID:: PMC6037477

Abstract Article PDF–1.5M

Select item 601069910.

MiR‐21 improves invasion and migration of drug‐resistant lung adenocarcinoma cancer cell and transformation of EMT through targeting HBP1

Chongyu Su, Xu Cheng, Yunsong Li, Yi Han, Xiaoyun Song, Daping Yu, Xiaoqing Cao, Zhidong Liu

Cancer Med. 2018 Jun; 7(6): 2485–2503. Published online 2018 Apr 16. doi: 10.1002/cam4.1294

PMCID:: PMC6010699

Abstract Article PDF–2.5M

Select item 583339411.

HMG-box transcription factor 1: a positive regulator of the G1/S transition through the Cyclin-CDK-CDKI molecular network in nasopharyngeal carcinoma

Shiwei He, Sheng Yang, Man Niu, Yancheng Zhong, Dan Gao, Yanru Zhang, Haotian Ma, Wei Xiong, Ming Zhou, Yanhong Zhou, Bo Xiang, Guiyuan Li, Cijun Shuai, Shuping Peng

Cell Death Dis. 2018 Feb; 9(2): 100. Published online 2018 Jan 24. doi: 10.1038/s41419-017-0175-4

PMCID:: PMC5833394

Abstract Article PDF–5.4M

Select item 543722912.

A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis

Shuya Wang, Zhengyi Cao, Junhui Xue, Hui Li, Wei Jiang, Yuning Cheng, Gang Li, Xiaowei Zhang

J Biol Chem. 2017 May 19; 292(20): 8207–8222. Published online 2017 Mar 27. doi: 10.1074/jbc.M116.768101

PMCID:: PMC5437229

Abstract Article PDF–3.5M

Select item 536242413.

Transcription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer

Chien-Yi Chan, Shih-Yi Huang, Jim Jinn-Chyuan Sheu, Mendel M. Roth, I-Tai Chou, Chia-Hsien Lien, Ming-Fen Lee, Chun-Yin Huang

Oncotarget. 2017 Feb 28; 8(9): 14537–14548. Published online 2017 Jan 14. doi: 10.18632/oncotarget.14653

PMCID:: PMC5362424

Abstract Article PDF–1.9M

Select item 528288414.

Up-regulated NRIP2 in colorectal cancer initiating cells modulates the Wnt pathway by targeting RORβ

Zhenzhen Wen, Tianhui Pan, Saisai Yang, Jingwen Liu, Haiying Tao, Yiming Zhao, Dingting Xu, Wei Shao, Jia Wu, Xiyong Liu, Yongjiang Wang, Jianshan Mao, Yongliang Zhu

Mol Cancer. 2017; 16: 20. Published online 2017 Jan 31. doi: 10.1186/s12943-017-0590-2

PMCID:: PMC5282884

Abstract Article PDF–2.3M

Select item 493344415.

HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis

Yifan Chen, Kewu Pan, Pingzhang Wang, Zhengyi Cao, Weibin Wang, Shuya Wang, Ningguang Hu, Junhui Xue, Hui Li, Wei Jiang, Gang Li, Xiaowei Zhang

J Biol Chem. 2016 Jun 10; 291(24): 12688–12705. Published online 2016 Apr 21. doi: 10.1074/jbc.M116.714147

PMCID:: PMC4933444

Abstract Article PDF–2.4M

Select item 474977516.

Transcription Factor HBP1 Enhances Radiosensitivity by Inducing Apoptosis in Prostate Cancer Cell Lines

Yicheng Chen, Yueping Wang, Yanlan Yu, Liwei Xu, Youyun Zhang, Shicheng Yu, Gonghui Li, Zhigeng Zhang

Anal Cell Pathol (Amst) 2016; 2016: 7015659. Published online 2016 Jan 28. doi: 10.1155/2016/7015659

PMCID:: PMC4749775

Abstract Article PDF–1.7M

Select item 461721117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 429537518.

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase

Tai Young Kim, Priscila F. Siesser, Kent L. Rossman, Dennis Goldfarb, Kathryn Mackinnon, Feng Yan, XianHua Yi, Michael J. MacCoss, Randall T. Moon, Channing J. Der, Michael B. Major

Mol Cell Biol. 2015 Jan; 35(1): 167–181. Prepublished online 2014 Oct 20. Published online 2014 Dec 9. doi: 10.1128/MCB.00857-14

PMCID:: PMC4295375

Abstract Article PDF–5.6M

Select item 419665119.

HBP1 promoter methylation augments the oncogenic β-catenin to correlate with prognosis in NSCLC

Ruo-Chia Tseng, Way-Ren Huang, Su-Feng Lin, Pei-Chen Wu, Han-Shui Hsu, Yi-Ching Wang

J Cell Mol Med. 2014 Sep; 18(9): 1752–1761. Published online 2014 Jun 4. doi: 10.1111/jcmm.12318

PMCID:: PMC4196651

Abstract Article PDF–786K

Select item 362669920.

Acetylation of Human TCF4 (TCF7L2) Proteins Attenuates Inhibition by the HBP1 Repressor and Induces a Conformational Change in the TCF4::DNA Complex

Susanne Elfert, Andreas Weise, Katja Bruser, Martin L. Biniossek, Sabine Jägle, Niklas Senghaas, Andreas Hecht

PLoS One. 2013; 8(4): e61867. Published online 2013 Apr 15. doi: 10.1371/journal.pone.0061867

PMCID:: PMC3626699

Abstract Article PDF–3.2M

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