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Select item 114475551.

Sclerotic-Type Cutaneous Chronic Graft-Versus-Host Disease Exhibits Activation of T Helper 1 and OX40 Cytokines

Madeline Kim, Yael Renert-Yuval, Polina Stepensky, Ehud Even-Or, Irina Zaidman, Tahel Fachler, Michal Neumark, Mariana Zamir, Monali NandyMazumdar, Digpal Gour, Paola Facheris, Britta Carroll, Ying Liu, Mitchelle L. Yu Ekey, Elizabeth Andrews, Marguerite Meariman, Michael Angelov, Swaroop Bose, Yeriel D. Estrada, Vered Molho-Pessach, Emma Guttman-Yassky

J Invest Dermatol. Author manuscript; available in PMC 2024 Oct 3.

Published in final edited form as: J Invest Dermatol. 2024 Mar; 144(3): 563–572.e9. Published online 2023 Sep 23. doi: 10.1016/j.jid.2023.08.026

PMCID:: PMC11447555

Abstract Article PDF–2.0M

Select item 111075692.

OX40 promotes obesity-induced adipose inflammation and insulin resistance

Bing Liu, Hengchi Yu, Guangyong Sun, Xiaojing Sun, Hua Jin, Chunpan Zhang, Wen Shi, Dan Tian, Kai Liu, Hufeng Xu, Xinmin Li, Jie Yin, Xu Hong, Dong Zhang

Cell Mol Life Sci. 2017 Oct; 74(20): 3827–3840. Published online 2017 Jun 13. doi: 10.1007/s00018-017-2552-7

PMCID:: PMC11107569

Abstract Article PDF–1.9M

Select item 110114713.

An OX-Tra’Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis

Kaviyon Sadrolashrafi, Lily Guo, Robin Kikuchi, Audrey Hao, Rebecca K. Yamamoto, Hannah C. Tolson, Sara N. Bilimoria, Danielle K. Yee, April W. Armstrong

Cells. 2024 Apr; 13(7): 587. Published online 2024 Mar 28. doi: 10.3390/cells13070587

PMCID:: PMC11011471

Abstract Article PDF–2.6M

Select item 106870854.

The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8⁺ T-cell immunity

Jizhang Yu, Jikai Cui, Xi Zhang, Heng Xu, Zhang Chen, Yuan Li, Yuqing Niu, Song Wang, Shuan Ran, Yanqiang Zou, Weicong Ye, Dan Zhang, Cheng Zhou, Jiahong Xia, Jie Wu

Cell Mol Immunol. 2023 Dec; 20(12): 1445–1456. Published online 2023 Nov 7. doi: 10.1038/s41423-023-01093-y

PMCID:: PMC10687085

Abstract Article PDF–4.8M

Select item 95082665.

Expression of the immune checkpoint modulator OX40 indicates poor survival in acute myeloid leukemia

Maddalena Marconato, Joseph Kauer, Helmut R. Salih, Melanie Märklin, Jonas S. Heitmann

Sci Rep. 2022; 12: 15856. Published online 2022 Sep 23. doi: 10.1038/s41598-022-19972-1

PMCID:: PMC9508266

Abstract Article PDF–1.9M

Select item 91288996.

The OX40 Axis is Associated with Both Systemic and Local Involvement in Atopic Dermatitis

Julie Sophie Hohwü ELSNER, Michael CARLSSON, Julie Kristine STOUGAARD, Uffe NYGAARD, Matthias BUCHNER, Regina FÖLSTER-HOLST, Malene HVID, Christian VESTERGAARD, Mette DELEURAN, Bent DELEURAN

Acta Derm Venereol. 2020; 100(6): 5712. Published online 2020 Mar 31. doi: 10.2340/00015555-3452

PMCID:: PMC9128899

Abstract Article PDF–710K

Select item 91072017.

Identification and validation of TNFRSF4 as a high-profile biomarker for prognosis and immunomodulation in endometrial carcinoma

Heng Ma, Peng-hui Feng, Shuang-ni Yu, Zhao-hui Lu, Qi Yu, Jie Chen

BMC Cancer. 2022; 22: 543. Published online 2022 May 13. doi: 10.1186/s12885-022-09654-6

Correction in:: BMC Cancer. 2022; 22: 592.

PMCID:: PMC9107201

Abstract Article PDF–13M

Select item 89013268.

Clinical Significance of OX40 and OX40 Ligand in the Peripheral Blood of Patients with Myasthenia Gravis

Xiaoling Zhou, Xiaoyuan Wang, Yanzheng Gu, Lan Chen, Yueping Shen, Jingluan Tian, Chen Shujun, Mingyuan Wang, Xiaoyu Duan, Hanqing Gao, Xiaopei Ji, Qi Fang, Xueguang Zhang, Qun Xue

J Immunol Res. 2022; 2022: 4337399. Published online 2022 Feb 28. doi: 10.1155/2022/4337399

PMCID:: PMC8901326

Abstract Article PDF–1.4M

Select item 86178229.

Roles of OX40 and OX40 Ligand in Mycosis Fungoides and Sézary Syndrome

Yuki Kawana, Hiraku Suga, Hiroaki Kamijo, Tomomitsu Miyagaki, Makoto Sugaya, Shinichi Sato

Int J Mol Sci. 2021 Nov; 22(22): 12576. Published online 2021 Nov 22. doi: 10.3390/ijms222212576

PMCID:: PMC8617822

Abstract Article PDF–3.4M

Select item 823426810.

Combined OX40 Agonist and PD-1 Inhibitor Immunotherapy Improves the Efficacy of Vascular Targeted Photodynamic Therapy in a Urothelial Tumor Model

Ricardo G. Alvim, Petrina Georgala, Lucas Nogueira, Alexander J. Somma, Karan Nagar, Jasmine Thomas, Laura Alvim, Amelia Riegel, Christopher Hughes, Jie Chen, Augusto B. Reis, Souhil Lebdai, Avigdor Scherz, Steven Zanganeh, Rui Gardner, Kwanghee Kim, Jonathan A. Coleman

Molecules. 2021 Jun; 26(12): 3744. Published online 2021 Jun 19. doi: 10.3390/molecules26123744

PMCID:: PMC8234268

Abstract Article PDF–3.2M

Select item 807978211.

Peripheral TIGIT+ T Follicular Helper Cells That Produce High Levels of Interleukin-21 via OX40 Represent Disease Activity in IgG4-Related Disease

Mitsuhiro Akiyama, Katsuya Suzuki, Keiko Yoshimoto, Hidekata Yasuoka, Yuko Kaneko, Tsutomu Takeuchi

Front Immunol. 2021; 12: 651357. Published online 2021 Apr 14. doi: 10.3389/fimmu.2021.651357

PMCID:: PMC8079782

Abstract Article PDF–3.1M

Select item 799088612.

OX40L/OX40 Signal Promotes IL-9 Production by Mucosal MAIT Cells During Helicobacter pylori Infection

Siqi Ming, Mei Zhang, Zibin Liang, Chunna Li, Jianzhong He, Peiyu Chen, Shunxian Zhang, Xiaoli Niu, Shimei Deng, Lanlan Geng, Guoliang Zhang, Sitang Gong, Yongjian Wu

Front Immunol. 2021; 12: 626017. Published online 2021 Mar 11. doi: 10.3389/fimmu.2021.626017

PMCID:: PMC7990886

Abstract Article PDF–2.9M

Select item 721787413.

OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody

Hirofumi Ohmura, Kyoko Yamaguchi, Fumiyasu Hanamura, Mamoru Ito, Akitaka Makiyama, Keita Uchino, Hozumi Shimokawa, Shingo Tamura, Taito Esaki, Kenji Mitsugi, Yoshihiro Shibata, Hisanobu Oda, Kenji Tsuchihashi, Hiroshi Ariyama, Hitoshi Kusaba, Yoshinao Oda, Koichi Akashi, Eishi Baba

Br J Cancer. 2020 May 12; 122(10): 1507–1517. Published online 2020 Mar 23. doi: 10.1038/s41416-020-0810-1

PMCID:: PMC7217874

Abstract Article PDF–1.8M

Select item 691597014.

High OX-40 expression in the tumor immune infiltrate is a favorable prognostic factor of overall survival in non-small cell lung cancer

Erminia Massarelli, Vincent K. Lam, Edwin R. Parra, Jaime Rodriguez-Canales, Carmen Behrens, Lixia Diao, Jing Wang, Jorge Blando, Lauren A. Byers, Niranjan Yanamandra, Sara Brett, Peter Morley, Padmanee Sharma, James Allison, Ignacio I. Wistuba, John V. Heymach

J Immunother Cancer. 2019; 7: 351. Published online 2019 Dec 16. doi: 10.1186/s40425-019-0827-2

PMCID:: PMC6915970

Abstract Article PDF–1.0M

Select item 670134715.

Enhancement of the Soluble Form of OX40 and OX40L Costimulatory Molecules but Reduction of the Membrane Form in Type 1 Diabetes (T1D)

Jingnan An, Sisi Ding, Sicheng Li, Lili Sun, Xin Chang, Ziyi Huang, Bin Zhou, Chen Fang, Cuiping Liu, Xueguang Zhang

J Immunol Res. 2019; 2019: 1780567. Published online 2019 Aug 1. doi: 10.1155/2019/1780567

PMCID:: PMC6701347

Abstract Article PDF–1.2M

Select item 659205116.

Central Roles of OX40L-OX40 Interaction in the Induction and Progression of Human T Cell-Driven Acute Graft-versus-Host Disease

Trivendra Tripathi, Wenjie Yin, Yaming Xue, Sandra Zurawski, Haruyuki Fujita, Shino Hanabuchi, Yong-Jun Liu, SangKon Oh, HyeMee Joo

Immunohorizons. Author manuscript; available in PMC 2019 Jun 25.

Published in final edited form as: Immunohorizons. 2019 Mar; 3(3): 110–120. doi: 10.4049/immunohorizons.1900001

PMCID:: PMC6592051

Abstract Article PDF–1.3M

Select item 642174017.

Increased Expressions of OX40 and OX40 Ligand in Patients with Primary Immune Thrombocytopenia

Dawei Cui, Yan Lv, Xinwang Yuan, Guoxiang Ruan, Yu Zhang, Cuilin Yan, Dandan Xu, Mengen Lv, Yun Mao, Jianping Cao, Jie Jin, Jue Xie

J Immunol Res. 2019; 2019: 6804806. Published online 2019 Mar 3. doi: 10.1155/2019/6804806

PMCID:: PMC6421740

Abstract Article PDF–1.1M

Select item 592672518.

Expression of gp34 (OX40 Ligand) and OX40 on Human T Cell Clones

Naruhiko Takasawa, Naoto Ishii, Norikazu Higashimura, Kazuko Murata, Yuetsu Tanaka, Masataka Nakamura, Takeshi Sasaki, Kazuo Sugamura

Jpn J Cancer Res. 2001 Apr; 92(4): 377–382. doi: 10.1111/j.1349-7006.2001.tb01105.x

PMCID:: PMC5926725

Summary PDF–154K

Select item 590300719.

High OX40 expression in recurrent ovarian carcinoma is indicative for response to repeated chemotherapy

Michaela Ramser, Simone Eichelberger, Silvio Däster, Benjamin Weixler, Marko Kraljević, Robert Mechera, Athanasios Tampakis, Tarik Delko, Uwe Güth, Sylvia Stadlmann, Luigi Terracciano, Raoul A. Droeser, Gad Singer

BMC Cancer. 2018; 18: 425. Published online 2018 Apr 16. doi: 10.1186/s12885-018-4339-0

PMCID:: PMC5903007

Abstract Article PDF–1020K

Select item 577525720.

Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA

Nina Rehage, Elena Davydova, Christine Conrad, Gesine Behrens, Andreas Maiser, Jenny E. Stehklein, Sven Brenner, Juliane Klein, Aicha Jeridi, Anne Hoffmann, Eunhae Lee, Umberto Dianzani, Rob Willemsen, Regina Feederle, Kristin Reiche, Jörg Hackermüller, Heinrich Leonhardt, Sonia Sharma, Dierk Niessing, Vigo Heissmeyer

Nat Commun. 2018; 9: 299. Published online 2018 Jan 19. doi: 10.1038/s41467-017-02582-1

PMCID:: PMC5775257

Abstract Article PDF–2.9M

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