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Items: 1 to 20 of 169

1.
Cyld restrains the hyperactivation of synovial fibroblasts in inflammatory arthritis by regulating the TAK1/IKK2 signaling axis
Vagelis Rinotas, Kalliopi Iliaki, Lydia Pavlidi, Theodore Meletakos, George Mosialos, Marietta Armaka
Cell Death Dis. 2024 Aug; 15(8): 584. Published online 2024 Aug 9. doi: 10.1038/s41419-024-06966-2
PMCID:
PMC11316070
AbstractArticlePDF–3.5M
2.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
3.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740
PMCID:
PMC11109483
AbstractArticlePDF–2.9M
4.
Megalosplenia as an initial manifestation of multiple myeloma with a novel CYLD gene mutation: A case report and literature review
Jinjing Zhang, Rui Zhang
Medicine (Baltimore) 2024 Apr 5; 103(14): e37624. Published online 2024 Apr 5. doi: 10.1097/MD.0000000000037624
PMCID:
PMC10994412
AbstractArticlePDF–667K
5.
TNF and IFNγ-induced cell death requires IRF1 and ELAVL1 to promote CASP8 expression
Buhao Deng, Jingyi Wang, Tingyun Yang, Zhao Deng, Jiafan Yuan, Bohan Zhang, Zhen Zhou, Fang Chen, Lu Fang, Chengzhi Liang, Bo Yan, Youwei Ai
J Cell Biol. 2024 Mar 4; 223(3): e202305026. Published online 2024 Feb 6. doi: 10.1083/jcb.202305026
PMCID:
PMC10847335
AbstractArticlePDF–8.1M
6.
CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma
Yueshuo Li, Chenxing Yang, Longlong Xie, Feng Shi, Min Tang, Xiangjian Luo, Na Liu, Xudong Hu, Yongwei Zhu, Ann M. Bode, Qiang Gao, Jian Zhou, Jia Fan, Xuejun Li, Ya Cao
Cell Death Dis. 2024 Jan; 15(1): 95. Published online 2024 Jan 29. doi: 10.1038/s41419-024-06419-w
PMCID:
PMC10824711
AbstractArticlePDF–6.4M
7.
CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression
Yanan Gu, Shiqi Wu, Junjie Fan, Zeji Meng, Guoqiang Gao, Tianjie Liu, Qi Wang, Huayu Xia, Xinyang Wang, Kaijie Wu
Cell Death Dis. 2024 Jan; 15(1): 79. Published online 2024 Jan 22. doi: 10.1038/s41419-024-06464-5
PMCID:
PMC10800345
AbstractArticlePDF–11M
8.
An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses
Norton Cheng, JoAnn Trejo
J Biol Chem. 2023 Dec; 299(12): 105370. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105370
PMCID:
PMC10694601
AbstractArticlePDF–5.0M
9.
CYLD stimulates macrophage phagocytosis of leukemic cells through STAT1 signalling in acute myeloid leukemia
Nguyen Thanh Huyen, Nguyen Thy Ngoc, Nguyen Hoang Giang, Do Thi Trang, Ha Hong Hanh, Vu Duc Binh, Nguyen Van Giang, Nguyen Xuan Canh, Nguyen Thi Xuan
PLoS One. 2023; 18(8): e0283586. Published online 2023 Aug 7. doi: 10.1371/journal.pone.0283586
PMCID:
PMC10406188
AbstractArticlePDF–1.8M
10.
A Tumor Suppressive Role of CYLD as a Novel Potential DUB of Aurora B in Cervical Cancer
Yufan Huang, Wei Zhang, Zhihui Yu, Hongkai Su, Bin Zeng, Jinsong Piao, Jing Wang, Juan Wu
Clin Med Insights Oncol. 2023; 17: 11795549231180832. Published online 2023 Jun 21. doi: 10.1177/11795549231180832
PMCID:
PMC10288423
AbstractArticlePDF–1.8M
11.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
12.
The Potential of Cylindromatosis (CYLD) as a Therapeutic Target in Oxidative Stress-Associated Pathologies: A Comprehensive Evaluation
Zhenzhou Huang, Yanjie Tan
Int J Mol Sci. 2023 May; 24(9): 8368. Published online 2023 May 6. doi: 10.3390/ijms24098368
PMCID:
PMC10179184
AbstractArticlePDF–1.3M
13.
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease
Ketu Mishra-Gorur, Tanyeri Barak, Leon D. Kaulen, Octavian Henegariu, Sheng Chih Jin, Stephanie Marie Aguilera, Ezgi Yalbir, Gizem Goles, Sayoko Nishimura, Danielle Miyagishima, Lydia Djenoune, Selin Altinok, Devendra K. Rai, Stephen Viviano, Andrew Prendergast, Cynthia Zerillo, Kent Ozcan, Burcin Baran, Leman Sencar, Nukte Goc, Yanki Yarman, A. Gulhan Ercan-Sencicek, Kaya Bilguvar, Richard P. Lifton, Jennifer Moliterno, Angeliki Louvi, Shiaulou Yuan, Engin Deniz, Martina Brueckner, Murat Gunel
Proc Natl Acad Sci U S A. 2023 Apr 18; 120(16): e2214997120. Published online 2023 Apr 12. doi: 10.1073/pnas.2214997120
PMCID:
PMC10120005
AbstractArticlePDF–9.8M
14.
MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas
Marthe Minderman, Hildo C. Lantermans, Leonie J. Grüneberg, Saskia A. G. M. Cillessen, Richard J. Bende, Carel J. M. van Noesel, Marie José Kersten, Steven T. Pals, Marcel Spaargaren
Blood Cancer J. 2023 Dec; 13(1): 37. Published online 2023 Mar 15. doi: 10.1038/s41408-023-00809-7
PMCID:
PMC10017792
AbstractArticlePDF–3.7M
15.
Interactomes of Glycogen Synthase Kinase-3 Isoforms
Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett
J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825
PMCID:
PMC9990120
AbstractArticlePDF–3.7M
16.
Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum
Shu-yi Tan, Jin-xiang Jiang, Hui-xian Huang, Xiu-ping Mo, Jing-ru Feng, Yu Chen, Li Yang, Cheng Long
Front Mol Neurosci. 2023; 16: 1107355. Published online 2023 Feb 8. doi: 10.3389/fnmol.2023.1107355
Correction in:
Front Mol Neurosci. 2023; 16: 1162275.
PMCID:
PMC9945542
AbstractArticlePDF–12M
17.
Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1
Ruoshi Peng, Chris Kedong Wang, Xuan Wang‐Kan, Manja Idorn, Majken Kjær, Felix Y Zhou, Berthe Katrine Fiil, Frederik Timmermann, Susana L Orozco, Julia McCarthy, Carol S Leung, Xin Lu, Katrin Bagola, Jan Rehwinkel, Andrew Oberst, Jonathan Maelfait, Søren R Paludan, Mads Gyrd‐Hansen
EMBO Rep. 2022 Dec; 23(12): e55839. Published online 2022 Oct 21. doi: 10.15252/embr.202255839
PMCID:
PMC9724671
AbstractArticlePDF–1.8M
18.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
19.
CYLD variants identified in Alzheimer's disease and frontotemporal dementia patients
Xuewen Xiao, Tianyan Xu, Hui Liu, Xixi Liu, Xinxin Liao, Yafang Zhou, Lu Zhou, Xin Wang, Yuan Zhu, Qijie Yang, Xiaoli Hao, Yingzi Liu, Hong Jiang, Jifeng Guo, Junling Wang, Beisha Tang, Jinchen Li, Lu Shen, Bin Jiao
Ann Clin Transl Neurol. 2022 Oct; 9(10): 1596–1601. Published online 2022 Aug 24. doi: 10.1002/acn3.51655
PMCID:
PMC9539372
AbstractArticlePDF–406K
20.
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB
Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan
EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698
PMCID:
PMC9433938
AbstractArticlePDF–9.3M

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