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Items: 1 to 20 of 136

1.
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2
D. Vacondio, H. Nogueira Pinto, L. Coenen, I. A. Mulder, R. Fontijn, B. van het Hof, W. K. Fung, A. Jongejan, G. Kooij, N. Zelcer, A. J. Rozemuller, H. E. de Vries, N. M. de Wit
Cell Death Dis. 2023 Nov; 14(11): 781. Published online 2023 Nov 28. doi: 10.1038/s41419-023-06316-8
PMCID:
PMC10684660
AbstractArticlePDF–5.0M
2.
Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB
Arturo González de la Aleja, Cristina Herrero, Mónica Torres-Torresano, María Teresa Schiaffino, Alejandro del Castillo, Bárbara Alonso, Miguel A. Vega, Amaya Puig-Kröger, Antonio Castrillo, Ángel L. Corbí
Cell Mol Life Sci. 2023 Apr; 80(4): 96. Published online 2023 Mar 17. doi: 10.1007/s00018-023-04745-4
PMCID:
PMC10020776
AbstractArticlePDF–4.5M
3.
Contributions of NR1H3 genetic polymorphisms to susceptibility and effects of narrowband UVB phototherapy to nonsegmental vitiligo
Meifeng Xu, Qiuyu Xu, Yan Liu, Xiaoli Li, Mei Wang, Wei Dong, Yuning Song, Shengxiang Xiao
Sci Rep. 2023; 13: 3384. Published online 2023 Feb 28. doi: 10.1038/s41598-023-30047-7
PMCID:
PMC9974977
AbstractArticlePDF–1.2M
4.
Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages
Suzanne A.E. van Wouw, Marlene van den Berg, Maroua El Ouraoui, Amber Meurs, Jenina Kingma, Roelof Ottenhoff, Melanie Loix, Marten A. Hoeksema, Koen Prange, Gerard Pasterkamp, Jerome J.A. Hendriks, Jeroen F.J. Bogie, Jan B. van Klinken, Frederic M. Vaz, Aldo Jongejan, Menno P.J. de Winther, Noam Zelcer
J Lipid Res. 2023 Feb; 64(2): 100325. Published online 2022 Dec 31. doi: 10.1016/j.jlr.2022.100325
PMCID:
PMC9926310
AbstractArticlePDF–2.6M
5.
Transcriptional Regulation of Carboxylesterase 1 in Human Liver: Role of the Nuclear Receptor Subfamily 1 Group H Member 3 and Its Splice Isoforms
Joseph M. Collins, Rong Lu, Xinwen Wang, Hao-Jie Zhu, Danxin Wang
Drug Metab Dispos. 2022 Jan; 50(1): 43–48. Published online 2022 Jan. doi: 10.1124/dmd.121.000649
PMCID:
PMC8969197
AbstractArticlePDF–686K
6.
RNA binding Motif protein-38 regulates myocardial hypertrophy in LXR-α-dependent lipogenesis pathway
Yao Li, Yanhu Shi, Yaoli He, Xiaoming Li, Junlu Yang
Bioengineered. 2021; 12(2): 9655–9667. Published online 2021 Dec 2. doi: 10.1080/21655979.2021.1977552
PMCID:
PMC8809983
AbstractArticlePDF–2.4M
7.
Myeloid-Derived Suppressive Cells Deficient in Liver X Receptor α Protected From Autoimmune Hepatitis
Bo Li, Min Lian, Yikang Li, Qiwei Qian, Jun Zhang, Qiaoyan Liu, Ruqi Tang, Xiong Ma
Front Immunol. 2021; 12: 732102. Published online 2021 Aug 26. doi: 10.3389/fimmu.2021.732102
PMCID:
PMC8427166
AbstractArticlePDF–5.5M
8.
Cytoplasmic LXR expression is an independent marker of poor prognosis for patients with early stage primary breast cancer
Wanting Shao, Christina Kuhn, Doris Mayr, Nina Ditsch, Magdalena Kailuwait, Verena Wolf, Nadia Harbeck, Sven Mahner, Udo Jeschke, Vincent Cavaillès, Sophie Sixou
J Cancer Res Clin Oncol. 2021; 147(9): 2535–2544. Published online 2021 Jun 3. doi: 10.1007/s00432-021-03670-y
Correction in:
J Cancer Res Clin Oncol. 2021; 147(9): 2545–2546.
PMCID:
PMC8310839
AbstractArticlePDF–1.3M
9.
LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function
Kirsty E. Waddington, George A. Robinson, Beatriz Rubio-Cuesta, Eden Chrifi-Alaoui, Sara Andreone, Kok-Siong Poon, Iveta Ivanova, Lucia Martin-Gutierrez, Dylan M. Owen, Elizabeth C. Jury, Inés Pineda-Torra
Proc Natl Acad Sci U S A. 2021 May 25; 118(21): e2017394118. Published online 2021 May 18. doi: 10.1073/pnas.2017394118
PMCID:
PMC8166169
AbstractArticlePDF–2.4M
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer
Samantha A. Hutchinson, Alex Websdale, Giorgia Cioccoloni, Hanne Røberg-Larsen, Priscilia Lianto, Baek Kim, Ailsa Rose, Chrysa Soteriou, Arindam Pramanik, Laura M. Wastall, Bethany J. Williams, Madeline A. Henn, Joy J. Chen, Liqian Ma, J. Bernadette Moore, Erik Nelson, Thomas A. Hughes, James L. Thorne
Oncogene. 2021; 40(16): 2872–2883. Published online 2021 Mar 19. doi: 10.1038/s41388-021-01720-w
PMCID:
PMC8062267
AbstractArticlePDF–2.3M
12.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
AbstractArticlePDF–6.8M
13.
Association between LXR-α and ABCA1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus in a Chinese Han Population
Peng Liu, Liang Ma, Hailing Zhao, Zhengri Shen, Xuefeng Zhou, Meihua Yan, Tingting Zhao, Haojun Zhang, Xinping Qiu, Ping Li
J Diabetes Res. 2020; 2020: 8721536. Published online 2020 Dec 22. doi: 10.1155/2020/8721536
PMCID:
PMC7772016
AbstractArticlePDF–385K
14.
Upregulation of miR-124-3p by Liver X Receptor Inhibits the Growth of Hepatocellular Carcinoma Cells Via Suppressing Cyclin D1 and CDK6
Dan Zhong, Xilin Lyu, Xiaohong Fu, Peng Xie, Menggang Liu, Fengtian He, Gang Huang
Technol Cancer Res Treat. 2020; 19: 1533033820967473. Published online 2020 Oct 19. doi: 10.1177/1533033820967473
PMCID:
PMC7592319
AbstractArticlePDF–1.0M
15.
miR-203 promotes HaCaT cell overproliferation through targeting LXR-α and PPAR-γ
Yueyuan Xiao, Haizhen Wang, Chang Wang, Bijun Zeng, Xueyong Tang, Yujin Zhang, Youhua Peng, Meijunzi Luo, Pan Huang, Zhibo Yang
Cell Cycle. 2020; 19(15): 1928–1940. Published online 2020 Jun 28. doi: 10.1080/15384101.2020.1783934
PMCID:
PMC7469443
AbstractArticlePDF–12M
16.
LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription
Zhongjie Lin, Shunjie Xia, Yuelong Liang, Lin Ji, Yu Pan, Shi Jiang, Zhe Wan, Liye Tao, Jiang Chen, Chengping Lin, Xiao Liang, Junjie Xu, Xiujun Cai
Theranostics. 2020; 10(19): 8834–8850. Published online 2020 Jul 11. doi: 10.7150/thno.45158
PMCID:
PMC7392029
AbstractArticlePDF–3.7M
17.
The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy
Bo Yang, Bin Zhang, Zhifei Cao, Xingdong Xu, Zihe Huo, Pan Zhang, Shufen Xiang, Zhe Zhao, Chunping Lv, Mei Meng, Gaochuan Zhang, Liang Dong, Shucheng Shi, Lan Yang, Quansheng Zhou
Cell Death Differ. 2020 Aug; 27(8): 2433–2450. Published online 2020 Mar 6. doi: 10.1038/s41418-020-0514-3
Correction in:
Cell Death Differ. 2020 Sep; 27(9): 2746.
PMCID:
PMC7370224
AbstractArticlePDF–4.8M
18.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
19.
LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes
Yahya Sohrabi, Glenn V. H. Sonntag, Laura C. Braun, Sina M. M. Lagache, Marie Liebmann, Luisa Klotz, Rinesh Godfrey, Florian Kahles, Johannes Waltenberger, Hannes M. Findeisen
Front Immunol. 2020; 11: 353. Published online 2020 Mar 10. doi: 10.3389/fimmu.2020.00353
PMCID:
PMC7077358
AbstractArticlePDF–5.4M
20.
Niacin regulates apolipoprotein M expression via liver X receptor-α
Liu Yang, Tie Li, Shuiping Zhao, Saidan Zhang
Mol Med Rep. 2019 Oct; 20(4): 3285–3291. Published online 2019 Aug 6. doi: 10.3892/mmr.2019.10557
PMCID:
PMC6755166
AbstractArticlePDF–522K

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