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Select item 91393191.

Identification of UDP-Glucuronosyltransferase 2B15 (UGT2B15) as a Target for IGF1 and Insulin Action

Rive Sarfstein, Karthik Nagaraj, Shivang Parikh, Carmit Levy, Zvi Laron, Dafna Benayahu, Haim Werner

Cells. 2022 May; 11(10): 1627. Published online 2022 May 12. doi: 10.3390/cells11101627

PMCID:: PMC9139319

Abstract Article PDF–2.6M

Select item 86396682.

TRIP12 Ubiquitination of Glucocerebrosidase Contributes to Neurodegeneration in Parkinson’s Disease

Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi-Xun Ma, Seung-Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae-In Kam, Kwangsoo Kim, Senthilkumar S Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding-Ochoa, Olga Pletnikova, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko

Neuron. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3758–3774.e11. Published online 2021 Oct 12. doi: 10.1016/j.neuron.2021.09.031

PMCID:: PMC8639668

Abstract Article PDF–2.6M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79015434.

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells

Farideh Shafiee-Kermani, Skyla T. Carney, Dereje Jima, Utibe C. Utin, LaNeisha B. Farrar, Melvin O. Oputa, Marcono R. Hines, Jr. H. Karimi Kinyamu, Kevin W. Trotter, Trevor K. Archer, Cathrine Hoyo, Beverly H. Koller, Stephen J. Freedland, Delores J. Grant

Epigenetics. 2021; 16(3): 289–299. Published online 2020 Jul 27. doi: 10.1080/15592294.2020.1795601

PMCID:: PMC7901543

Abstract Article PDF–1.0M

Select item 72200895.

The correlation between UDP-glucuronosyltransferase polymorphisms and environmental endocrine disruptors levels in polycystic ovary syndrome patients

Yunyao Luo, Ying Nie, Lu Tang, Charles C. Xu, Liangzhi Xu

Medicine (Baltimore) 2020 Mar; 99(11): e19444. Published online 2020 Mar 13. doi: 10.1097/MD.0000000000019444

PMCID:: PMC7220089

Abstract Article PDF–318K

Select item 71535656.

Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells

Dianke Yu, Jing Chen, Si Chen, Lin Xu, Leihong Wu, Dongying Li, Jiao Luo, Yuan Jin, Yanjie Zhao, Bridgett Knox, William H. Tolleson, Xubing Wang, Lei Guo, Weida Tong, Baitang Ning

Drug Metab Dispos. 2020 Apr; 48(4): 297–306. Published online 2020 Apr. doi: 10.1124/dmd.119.090043

Correction in:: Drug Metab Dispos. 2020 May; 48(5): 386.

PMCID:: PMC7153565

Abstract Article PDF–1.3M

Select item 61886387.

Identification and validation of the microRNA response elements in the 3’-untranslated region of the UDP glucuronosyltransferase (UGT) 2B7 and 2B15 genes by a functional genomics approach

Ioannis Papageorgiou, Michael H. Court

Biochem Pharmacol. Author manuscript; available in PMC 2018 Dec 15.

Published in final edited form as: Biochem Pharmacol. 2017 Dec 15; 146: 199–213. Published online 2017 Sep 28. doi: 10.1016/j.bcp.2017.09.013

PMCID:: PMC6188638

Abstract Article PDF–1.1M

Select item 61117088.

Bioinformatic analysis suggests that UGT2B15 activates the Hippo-YAP signaling pathway leading to the pathogenesis of gastric cancer

Xuanmin Chen, Defeng Li, Nannan Wang, Meifeng Yang, Aijun Liao, Shuling Wang, Guangsheng Hu, Bing Zeng, Yuhong Yao, Diqun Liu, Han Liu, Weiwei Zhou, Weisheng Xiao, Peiyuan Li, Chen Ming, Song Ping, Pingfang Chen, Li Jing, Yu Bai, Jun Yao

Oncol Rep. 2018 Oct; 40(4): 1855–1862. Published online 2018 Jul 26. doi: 10.3892/or.2018.6604

PMCID:: PMC6111708

Abstract Article PDF–759K

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 458182610.

Histopathology of melanosis coli and determination of its associated genes by comparative analysisof expression microarrays

XIAO-AN LI, YAN ZHOU, SHU-XIAN ZHOU, HAI-RONG LIU, JIN-MEI XU, LONG GAO, XIAN-JING YU, XIAO-HUI LI

Mol Med Rep. 2015 Oct; 12(4): 5807–5815. Published online 2015 Jul 27. doi: 10.3892/mmr.2015.4126

PMCID:: PMC4581826

Abstract Article PDF–1.4M

Select item 450340411.

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients

Alicia Romero-Lorca, Apolonia Novillo, María Gaibar, Fernando Bandrés, Ana Fernández-Santander

PLoS One. 2015; 10(7): e0132269. Published online 2015 Jul 15. doi: 10.1371/journal.pone.0132269

Correction in:: PLoS One. 2015; 10(10): e0140921.

PMCID:: PMC4503404

Abstract Article PDF–932K

Select item 427112412.

Human Hepatic UGT2B15 Developmental Expression

Karthika Divakaran, Ronald N. Hines, D Gail McCarver

Toxicol Sci. 2014 Sep 1; 141(1): 292–299. Published online 2014 Sep 12. doi: 10.1093/toxsci/kfu126

PMCID:: PMC4271124

Abstract Article PDF–1.0M

Select item 404888013.

The Effect of UGT1A and UGT2B Polymorphisms on Colorectal Cancer Risk: Haplotype Associations and Gene-Environment Interactions

Andrea Y. Angstadt, Terryl J. Hartman, Samuel M. Lesko, Joshua E. Muscat, Junjia Zhu, Carla J. Gallagher, Philip Lazarus

Genes Chromosomes Cancer. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Genes Chromosomes Cancer. 2014 Jun; 53(6): 454–466. doi: 10.1002/gcc.22157

PMCID:: PMC4048880

Abstract Article PDF–860K

Select item 392434714.

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study

Adriana C Vidal, Cocoa Tucker, Joellen M Schildkraut, Ricardo M Richardson, Megan McPhail, Stephen J Freedland, Cathrine Hoyo, Delores J Grant

BMC Cancer. 2013; 13: 556. Published online 2013 Nov 22. doi: 10.1186/1471-2407-13-556

PMCID:: PMC3924347

Abstract Article PDF–240K

Select item 373857415.

Prognostic Significance of ESR1 Amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 Polymorphisms in Breast Cancer Patients

Aleksandra Markiewicz, Marzena Wełnicka-Jaśkiewicz, Jarosław Skokowski, Janusz Jaśkiewicz, Jolanta Szade, Jacek Jassem, Anna J. Żaczek

PLoS One. 2013; 8(8): e72219. Published online 2013 Aug 8. doi: 10.1371/journal.pone.0072219

PMCID:: PMC3738574

Abstract Article PDF–721K

Select item 340055316.

A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation

Andrea D. Coviello, Robin Haring, Melissa Wellons, Dhananjay Vaidya, Terho Lehtimäki, Sarah Keildson, Kathryn L. Lunetta, Chunyan He, Myriam Fornage, Vasiliki Lagou, Massimo Mangino, N. Charlotte Onland-Moret, Brian Chen, Joel Eriksson, Melissa Garcia, Yong Mei Liu, Annemarie Koster, Kurt Lohman, Leo-Pekka Lyytikäinen, Ann-Kristin Petersen, Jennifer Prescott, Lisette Stolk, Liesbeth Vandenput, Andrew R. Wood, Wei Vivian Zhuang, Aimo Ruokonen, Anna-Liisa Hartikainen, Anneli Pouta, Stefania Bandinelli, Reiner Biffar, Georg Brabant, David G. Cox, Yuhui Chen, Steven Cummings, Luigi Ferrucci, Marc J. Gunter, Susan E. Hankinson, Hannu Martikainen, Albert Hofman, Georg Homuth, Thomas Illig, John-Olov Jansson, Andrew D. Johnson, David Karasik, Magnus Karlsson, Johannes Kettunen, Douglas P. Kiel, Peter Kraft, Jingmin Liu, Östen Ljunggren, Mattias Lorentzon, Marcello Maggio, Marcello R. P. Markus, Dan Mellström, Iva Miljkovic, Daniel Mirel, Sarah Nelson, Laure Morin Papunen, Petra H. M. Peeters, Inga Prokopenko, Leslie Raffel, Martin Reincke, Alex P. Reiner, Kathryn Rexrode, Fernando Rivadeneira, Stephen M. Schwartz, David Siscovick, Nicole Soranzo, Doris Stöckl, Shelley Tworoger, André G. Uitterlinden, Carla H. van Gils, Ramachandran S. Vasan, H.-Erich Wichmann, Guangju Zhai, Shalender Bhasin, Martin Bidlingmaier, Stephen J. Chanock, Immaculata De Vivo, Tamara B. Harris, David J. Hunter, Mika Kähönen, Simin Liu, Pamela Ouyang, Tim D. Spector, Yvonne T. van der Schouw, Jorma Viikari, Henri Wallaschofski, Mark I. McCarthy, Timothy M. Frayling, Anna Murray, Steve Franks, Marjo-Riitta Järvelin, Frank H. de Jong, Olli Raitakari, Alexander Teumer, Claes Ohlsson, Joanne M. Murabito, John R. B. Perry

PLoS Genet. 2012 Jul; 8(7): e1002805. Published online 2012 Jul 19. doi: 10.1371/journal.pgen.1002805