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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 78649582.

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures

Anikó Rátkai, Krisztián Tárnok, Hajar El Aouad, Brigitta Micska, Katalin Schlett, Attila Szücs

Sci Rep. 2021; 11: 3236. Published online 2021 Feb 5. doi: 10.1038/s41598-021-82775-3

PMCID:: PMC7864958

Abstract Article PDF–5.4M

Select item 77816413.

Trigeminal neuropathic pain is alleviated by inhibition of Ca_v3.3 T-type calcium channels in mice

Marena Montera, Aleyah Goins, Leos Cmarko, Norbert Weiss, Karin N. Westlund, Sascha R. A. Alles

Channels (Austin) 2021; 15(1): 31–37. Published online 2020 Dec 23. doi: 10.1080/19336950.2020.1859248

PMCID:: PMC7781641

Abstract Article PDF–580K

Select item 77258064.

Global genetic deletion of Ca_V3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers

Simon Feseha, Tamara Timic Stamenic, Damon Wallace, Caesare Tamag, Lingling Yang, Jen Q. Pan, Slobodan M. Todorovic

Sci Rep. 2020; 10: 21510. Published online 2020 Dec 9. doi: 10.1038/s41598-020-78488-8

PMCID:: PMC7725806

Abstract Article PDF–4.4M

Select item 70264445.

Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits

Ayan Ghoshal, David S. Uygun, Lingling Yang, James M. McNally, Violeta G. Lopez-Huerta, Mario A. Arias-Garcia, David Baez-Nieto, Andrew Allen, Megan Fitzgerald, Soonwook Choi, Qiangge Zhang, Jen M. Hope, Karena Yan, Xiaohong Mao, Thomas B. Nicholson, Kazuo Imaizumi, Zhanyan Fu, Guoping Feng, Ritchie E. Brown, Robert E. Strecker, Shaun M. Purcell, Jen Q. Pan

Transl Psychiatry. 2020; 10: 29. Published online 2020 Jan 23. doi: 10.1038/s41398-020-0685-1

PMCID:: PMC7026444

Abstract Article PDF–3.1M

Select item 67048956.

Synaptic Plasticity at Intrathalamic Connections via Ca_V3.3 T-type Ca²⁺ Channels and GluN2B-Containing NMDA Receptors

Simone Astori, Anita Lüthi

J Neurosci. 2013 Jan 9; 33(2): 624–630. doi: 10.1523/JNEUROSCI.3185-12.2013

PMCID:: PMC6704895

Abstract Article PDF–1.2M

Select item 65388537.

A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype

Dawei Wu, Ira Schieren, Yingzhi Qian, Chaolin Zhang, Thomas M. Jessell, Joriene C. de Nooij

J Neurosci. 2019 May 29; 39(22): 4252–4267. doi: 10.1523/JNEUROSCI.2671-18.2019

PMCID:: PMC6538853

Abstract Article PDF–6.3M

Select item 63425258.

Thalamic reticular control of local sleep in mouse sensory cortex

Laura MJ Fernandez, Gil Vantomme, Alejandro Osorio-Forero, Romain Cardis, Elidie Béard, Anita Lüthi

eLife. 2018; 7: e39111. Published online 2018 Dec 25. doi: 10.7554/eLife.39111

PMCID:: PMC6342525

Abstract Article PDF–4.1M

Select item 52958219.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 492609210.

Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels

Dong-Dong Liu, Jun-Mei Lu, Qian-Ru Zhao, Changlong Hu, Yan-Ai Mei

Sci Rep. 2016; 6: 28653. Published online 2016 Jun 29. doi: 10.1038/srep28653

PMCID:: PMC4926092

Abstract Article PDF–2.8M

Select item 475326311.

Contribution of postsynaptic T‐type calcium channels to parallel fibre‐Purkinje cell synaptic responses

Romain Ly, Guy Bouvier, German Szapiro, Haydn M. Prosser, Andrew D. Randall, Masanobu Kano, Kenji Sakimura, Philippe Isope, Boris Barbour, Anne Feltz

J Physiol. 2016 Feb 15; 594(4): 915–936. Published online 2016 Feb 14. doi: 10.1113/JP271623

PMCID:: PMC4753263

Abstract Article PDF–1.1M

Select item 448788112.

Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC‐β

Marc D. Basson, Bixi Zeng, Christina Downey, Madhu P. Sirivelu, Jetze J. Tepe

Mol Oncol. 2015 Feb; 9(2): 513–526. Published online 2014 Oct 23. doi: 10.1016/j.molonc.2014.10.008

PMCID:: PMC4487881

Abstract Article PDF–3.0M

Select item 413660513.

Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice

Seung Eun Lee, Jaekwang Lee, Charles Latchoumane, Boyoung Lee, Soo-Jin Oh, Zahangir Alam Saud, Cheongdahm Park, Ning Sun, Eunji Cheong, Chien-Chang Chen, Eui-Ju Choi, C. Justin Lee, Hee-Sup Shin

Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32): 11828–11833. Published online 2014 Jul 28. doi: 10.1073/pnas.1408609111

PMCID:: PMC4136605

Abstract Article PDF–1.3M

Select item 402491114.

Ca_v3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage

Shin-Shiou Lin, Bing-Hsiean Tzeng, Kuan-Rong Lee, Richard J. H. Smith, Kevin P. Campbell, Chien-Chang Chen

Proc Natl Acad Sci U S A. 2014 May 13; 111(19): E1990–E1998. Published online 2014 Apr 28. doi: 10.1073/pnas.1323112111

PMCID:: PMC4024911

Abstract Article PDF–1.5M

Select item 396495515.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315818418.

The Ca_V3.3 calcium channel is the major sleep spindle pacemaker in thalamus

Simone Astori, Ralf D. Wimmer, Haydn M. Prosser, Corrado Corti, Mauro Corsi, Nicolas Liaudet, Andrea Volterra, Paul Franken, John P. Adelman, Anita Lüthi

Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33): 13823–13828. Published online 2011 Aug 1. doi: 10.1073/pnas.1105115108

PMCID:: PMC3158184

Abstract Article PDF–3.7M

Select item 302253419.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 279025020.

Differential expression of membrane conductances underlies spontaneous event initiation by rostral midline neurons in the embryonic mouse hindbrain

Audrey M Moruzzi, Nauzley C Abedini, Matthew A Hansen, Julia E Olson, Martha M Bosma

J Physiol. 2009 Nov 1; 587(Pt 21): 5081–5093. Published online 2009 Sep 7. doi: 10.1113/jphysiol.2009.180091

PMCID:: PMC2790250

Abstract Article PDF–694K

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