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Select item 111117291.

The β-arrestin1/endothelin axis bolsters ovarian fibroblast-dependent invadosome activity and cancer cell metastatic potential

Danila Del Rio, Ilenia Masi, Valentina Caprara, Flavia Ottavi, Gabriele Albertini Petroni, Erica Salvati, Daniela Trisciuoglio, Sara Maria Giannitelli, Anna Bagnato, Emanuele Mauri, Francesca Spadaro, Laura Rosanò

Cell Death Dis. 2024 May; 15(5): 358. Published online 2024 May 22. doi: 10.1038/s41419-024-06730-6

PMCID:: PMC11111729

Abstract Article PDF–23M

Select item 111083862.

β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells

Icía Santos-Zas, Uxía Gurriarán-Rodríguez, Tania Cid-Díaz, Gabriela Figueroa, Jessica González-Sánchez, Mónica Bouzo-Lorenzo, Carlos S. Mosteiro, José Señarís, Felipe F. Casanueva, Xesús Casabiell, Rosalía Gallego, Yolanda Pazos, Vincent Mouly, Jesús P. Camiña

Cell Mol Life Sci. 2016 Feb; 73(3): 617–635. Published online 2015 Jul 27. doi: 10.1007/s00018-015-1994-z

PMCID:: PMC11108386

Abstract Article PDF–7.1M

Select item 106076563.

Testosterone and Prolactin Perturbations Possibly Associated with Reduced Levels of β-Arrestin1 in Mononuclear Leukocytes of Women with Premenstrual Dysphoric Disorder

Sanket Nayyar, Anthony Archibong, Tultul Nayyar

Int J Mol Sci. 2023 Oct; 24(20): 15449. Published online 2023 Oct 22. doi: 10.3390/ijms242015449

PMCID:: PMC10607656

Abstract Article PDF–2.7M

Select item 105895034.

The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor

Luciana M. Leo, Rufaida Al-Zoubi, Dow P. Hurst, Anna P. Stephan, Pingwei Zhao, Douglas G. Tilley, Elke Miess, Stefan Schulz, Mary E. Abood, Patricia H. Reggio

Cannabis Cannabinoid Res. October 2023; 8(5): 731–748. Published online 2023 Oct 9. doi: 10.1089/can.2021.0223

PMCID:: PMC10589503

Abstract Article PDF–1.2M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101000246.

Cannabinoid 1 (CB₁) receptor arrestin subtype‐selectivity and phosphorylation dependence

Jamie J. Manning, Gabriel Rawcliffe, David B. Finlay, Michelle Glass

Br J Pharmacol. 2023 Feb; 180(3): 369–382. Published online 2022 Nov 6. doi: 10.1111/bph.15973

PMCID:: PMC10100024

Abstract Article PDF–1.8M

Select item 98869217.

The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer

Ilenia Masi, Flavia Ottavi, Danila Del Rio, Valentina Caprara, Cristina Vastarelli, Sara Maria Giannitelli, Giulia Fianco, Pamela Mozetic, Marianna Buttarelli, Gabriella Ferrandina, Giovanni Scambia, Daniela Gallo, Alberto Rainer, Anna Bagnato, Francesca Spadaro, Laura Rosanò

Cell Death Dis. 2023 Jan; 14(1): 73. Published online 2023 Jan 30. doi: 10.1038/s41419-023-05612-7

Correction in:: Cell Death Dis. 2024 Oct; 15(10): 766.

PMCID:: PMC9886921

Abstract Article PDF–17M

Select item 95465818.

Dual roles of β-arrestin 1 in mediating cell metabolism and proliferation in gastric cancer

Huan Yu, Man Wang, Ting Zhang, Lihua Cao, Zhongwu Li, Yang Du, Yanru Hai, Xiangyu Gao, Jiafu Ji, Jianmin Wu

Proc Natl Acad Sci U S A. 2022 Oct 4; 119(40): e2123231119. Published online 2022 Sep 26. doi: 10.1073/pnas.2123231119

PMCID:: PMC9546581

Abstract Article PDF–4.6M

Select item 93485769.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 927928510.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 889702211.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 862139112.

Structural Basis of Arrestin Selectivity for Active Phosphorylated G Protein-Coupled Receptors

Preethi C. Karnam, Sergey A. Vishnivetskiy, Vsevolod V. Gurevich

Int J Mol Sci. 2021 Nov; 22(22): 12481. Published online 2021 Nov 19. doi: 10.3390/ijms222212481

PMCID:: PMC8621391

Abstract Article PDF–3.1M

Select item 844941013.

Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade

Changxiu Qu, Ji Young Park, Min Woo Yun, Qing-tao He, Fan Yang, Kiae Kim, Donghee Ham, Rui-rui Li, T. M. Iverson, Vsevolod V. Gurevich, Jin-Peng Sun, Ka Young Chung

Proc Natl Acad Sci U S A. 2021 Sep 14; 118(37): e2026491118. Published online 2021 Sep 10. doi: 10.1073/pnas.2026491118

PMCID:: PMC8449410

Abstract Article PDF–1.6M

Select item 825943614.

Amino terminal recognition by a CCR6 chemokine receptor antibody blocks CCL20 signaling and IL-17 expression via β-arrestin

Sara Gómez-Melero, Fé Isabel García-Maceira, Tania García-Maceira, Verónica Luna-Guerrero, Gracia Montero-Peñalvo, Isaac Túnez-Fiñana, Elier Paz-Rojas

BMC Biotechnol. 2021; 21: 41. Published online 2021 Jul 5. doi: 10.1186/s12896-021-00699-2

PMCID:: PMC8259436

Abstract Article PDF–2.3M

Select item 822311915.

ACE2 interaction with cytoplasmic PDZ protein enhances SARS-CoV-2 invasion

Qiangmin Zhang, Julia Gefter, W. Bruce Sneddon, Tatyana Mamonova, Peter A. Friedman

iScience. 2021 Jul 23; 24(7): 102770. Published online 2021 Jun 24. doi: 10.1016/j.isci.2021.102770

PMCID:: PMC8223119

Abstract Article PDF–3.0M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 816305417.

Host versus cell-dependent effects of β-arrestin 1 expression in prostate tumorigenesis

Timothy O Adekoya, Nikia Smith, Ariel J Thomas, Tonya S Lane, Nija Burnette, Elizabeth J Rivers, Yahui Li, Xiaoxin L Chen, Ricardo M Richardson

Carcinogenesis. 2021 May; 42(5): 772–783. Published online 2021 Mar 12. doi: 10.1093/carcin/bgab021

PMCID:: PMC8163054

Abstract Article PDF–15M

Select item 806263218.

Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2

Qing-Tao He, Peng Xiao, Shen-Ming Huang, Ying-Li Jia, Zhong-Liang Zhu, Jing-Yu Lin, Fan Yang, Xiao-Na Tao, Ru-Jia Zhao, Feng-Yuan Gao, Xiao-Gang Niu, Kun-Hong Xiao, Jiangyun Wang, Changwen Jin, Jin-Peng Sun, Xiao Yu

Nat Commun. 2021; 12: 2396. Published online 2021 Apr 22. doi: 10.1038/s41467-021-22731-x

PMCID:: PMC8062632

Abstract Article PDF–3.5M

Select item 790124519.

How GPCR phosphorylation patterns orchestrate arrestin-mediated signaling

Naomi R. Latorraca, Matthieu Masureel, Scott A. Hollingsworth, Franziska M. Heydenreich, Carl-Mikael Suomivuori, Connor Brinton, Raphael J.L. Townshend, Michel Bouvier, Brian K. Kobilka, Ron O. Dror

Cell. Author manuscript; available in PMC 2021 Dec 23.

Published in final edited form as: Cell. 2020 Dec 23; 183(7): 1813–1825.e18. Published online 2020 Dec 8. doi: 10.1016/j.cell.2020.11.014

PMCID:: PMC7901245

Abstract Article PDF–2.4M

Select item 785812820.

Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth

Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M. Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti

Mol Oncol. 2021 Feb; 15(2): 523–542. Published online 2020 Dec 31. doi: 10.1002/1878-0261.12800

PMCID:: PMC7858128

Abstract Article PDF–1.8M

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