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Select item 113010741.

Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17

Guillaume Dolla, Sarah Nicolas, Ligia Ramos dos Santos, Alexandre Bourgeois, Raphaëlle Pardossi-Piquard, Franck Bihl, Christelle Zaghrini, Joana Justino, Christine Payré, Pascal Mansuelle, Christoph Garbers, Pierre Ronco, Frédéric Checler, Gérard Lambeau, Agnès Petit-Paitel

J Biol Chem. 2024 Jul; 300(7): 107480. Published online 2024 Jun 17. doi: 10.1016/j.jbc.2024.107480

PMCID:: PMC11301074

Abstract Article PDF–4.9M

Select item 111555652.

Phospholipid metabolism-related genotypes of PLA2R1 and CERS4 contribute to nonobese MASLD

Congxiang Shao, Junzhao Ye, Zhi Dong, Bing Liao, Shiting Feng, Shixian Hu, Bihui Zhong

Hepatol Commun. 2024 Jun; 8(6): e0388. Published online 2024 Jun 5. doi: 10.1097/HC9.0000000000000388

PMCID:: PMC11155565

Abstract Article PDF–1.2M

Select item 109217023.

Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth

Shahbaz Khan, Jeffrey A. Zuccato, Vladimir Ignatchenko, Olivia Singh, Meinusha Govindarajan, Matthew Waas, Salvador Mejia-Guerrero, Andrew Gao, Gelareh Zadeh, Thomas Kislinger

Acta Neuropathol Commun. 2024; 12: 39. Published online 2024 Mar 7. doi: 10.1186/s40478-024-01751-w

PMCID:: PMC10921702

Abstract Article PDF–3.1M

Select item 103800054.

The Role of PLA2R in Primary Membranous Nephropathy: Do We Still Need a Kidney Biopsy?

Thomas McDonnell, Henry H. L. Wu, Smeeta Sinha, Rajkumar Chinnadurai

Genes (Basel) 2023 Jul; 14(7): 1343. Published online 2023 Jun 26. doi: 10.3390/genes14071343

PMCID:: PMC10380005

Abstract Article PDF–617K

Select item 92316235.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 89203816.

Association of serum mannose-binding lectin, anti-phospholipase A2 receptor antibody and renal outcomes in idiopathic membranous nephropathy and atypical membranous nephropathy: a single center retrospective cohort study

Yuchao Zhao, Meishun Cai, Zhenbin Jiang, Bao Dong, Yu Yan, Yina Wang, Li Zuo

Ren Fail. 2022; 44(1): 428–433. Published online 2022 Mar 10. doi: 10.1080/0886022X.2022.2048016

PMCID:: PMC8920381

Abstract Article PDF–604K

Select item 88069417.

Associations between m-type phospholipase A2 receptor,human leukocyte antigen gene polymorphisms and idiopathic membranous nephropathy

Xiaogang Liu, Weixi Xu, Chengyuan Yu, Mingao Wang, Ruichan Liu, Rujuan Xie

Bioengineered. 2021; 12(1): 8833–8844. Published online 2021 Oct 29. doi: 10.1080/21655979.2021.1987080

PMCID:: PMC8806941

Abstract Article PDF–570K

Select item 82020118.

Single-Cell Profiling Reveals Transcriptional Signatures and Cell-Cell Crosstalk in Anti-PLA2R Positive Idiopathic Membranous Nephropathy Patients

Jie Xu, Chanjuan Shen, Wei Lin, Ting Meng, Joshua D. Ooi, Peter J. Eggenhuizen, Rong Tang, Gong Xiao, Peng Jin, Xiang Ding, Yangshuo Tang, Weisheng Peng, Wannian Nie, Xiang Ao, Xiangcheng Xiao, Yong Zhong, Qiaoling Zhou

Front Immunol. 2021; 12: 683330. Published online 2021 May 31. doi: 10.3389/fimmu.2021.683330

PMCID:: PMC8202011

Abstract Article PDF–7.0M

Select item 78872709.

PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging

Anda Huna, Audrey Griveau, David Vindrieux, Sara Jaber, Jean-Michel Flaman, Delphine Goehrig, Lamia Azzi, Jean-Jacques Médard, Sophia Djebali, Hector Hernandez-Vargas, Robert Dante, Léa Payen, Jacqueline Marvel, Philippe Bertolino, Sébastien Aubert, Pierre Dubus, David Bernard

Cell Death Dis. 2021 Feb; 12(2): 190. Published online 2021 Feb 16. doi: 10.1038/s41419-021-03468-3

PMCID:: PMC7887270

Abstract Article PDF–2.0M

Select item 752927710.

PLA2R antibody, PLA2R rs4664308 polymorphism and PLA2R mRNA levels in Tunisian patients with primary membranous nephritis

Tarak Dhaouadi, Jihen Abdellatif, Raja Trabelsi, Hanene Gaied, Sameh Chamkhi, Imen Sfar, Rym Goucha, Fethi Ben Hamida, Taieb Ben Abdallah, Yousr Gorgi

PLoS One. 2020; 15(10): e0240025. Published online 2020 Oct 1. doi: 10.1371/journal.pone.0240025

PMCID:: PMC7529277

Abstract Article PDF–1.0M

Select item 747184011.

Autoantigens PLA2R and THSD7A in membranous nephropathy share a common epitope motif in the N-terminal domain

M. Fresquet, S.J. Rhoden, T.A. Jowitt, E.A. McKenzie, I. Roberts, R. Lennon, P.E. Brenchley

J Autoimmun. 2020 Jan; 106: 102308. doi: 10.1016/j.jaut.2019.102308

PMCID:: PMC7471840

Abstract Article

Select item 743208512.

Clinical Significance of Expression Changes and Promoter Methylation of PLA2R1 in Tissues of Breast Cancer Patients

Noha Mitwally, Einas Yousef, Ahmad Abd Al Aziz, Mohamed Taha

Int J Mol Sci. 2020 Aug; 21(15): 5453. Published online 2020 Jul 30. doi: 10.3390/ijms21155453

PMCID:: PMC7432085

Abstract Article PDF–4.1M

Select item 740332313.

Single-nucleotide polymorphism rs4664308 in PLA2R1 gene is associated with the risk of idiopathic membranous nephropathy: a meta-analysis

Masahiro Yoshikawa, Kensuke Asaba

Sci Rep. 2020; 10: 13119. Published online 2020 Aug 4. doi: 10.1038/s41598-020-70009-x

PMCID:: PMC7403323

Abstract Article PDF–2.6M

Select item 727008014.

Methylation of the Phospholipase A2 Receptor 1 Promoter Region in Childhood B Cell Acute Lymphoblastic Leukaemia

Markus Friedemann, Katharina Gutewort, Dana Thiem, Brit Nacke, Carsten Jandeck, Björn Sönke Lange, Olga Sukocheva, Meinolf Suttorp, Mario Menschikowski

Sci Rep. 2020; 10: 9058. Published online 2020 Jun 3. doi: 10.1038/s41598-020-65825-0

PMCID:: PMC7270080

Abstract Article PDF–1.2M

Select item 706505615.

Clinical value of renal phospholipase A2 receptor deposit in the prognosis evaluation and treatment options of idiopathic membranous nephropathy: A retrospective cohort study

Zhiyong Xie, Wei Dong, Zhilian Li, Yuanhan Chen, Li Song, Ruizhao Li, Yanhua Wu, Lei Fu, Huaban Liang, Yiming Tao, Jianteng Xie, Wenjian Wang, Shuangxin Liu, Zhiming Ye, Wei Shi, Xinling Liang

Nephrology (Carlton) 2020 Mar; 25(3): 219–229. Published online 2020 Jan 20. doi: 10.1111/nep.13691

PMCID:: PMC7065056

Abstract Article PDF–1.1M

Select item 669106416.

Immunological Pathogenesis of Membranous Nephropathy: Focus on PLA2R1 and Its Role

Wenbin Liu, Chang Gao, Haoran Dai, Yang Zheng, Zhaocheng Dong, Yu Gao, Fei Liu, Zihan Zhang, Zhiyuan Liu, Weijing Liu, Baoli Liu, Qingquan Liu, Jialan Shi

Front Immunol. 2019; 10: 1809. Published online 2019 Aug 6. doi: 10.3389/fimmu.2019.01809

PMCID:: PMC6691064

Abstract Article PDF–2.0M

Select item 626092217.

Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Audrey Griveau, Clotilde Wiel, Benjamin Le Calvé, Dorian V. Ziegler, Sophia Djebali, Marine Warnier, Nadine Martin, Jacqueline Marvel, David Vindrieux, Martin O. Bergo, David Bernard

Aging Cell. 2018 Dec; 17(6): e12835. Published online 2018 Sep 14. doi: 10.1111/acel.12835

PMCID:: PMC6260922

Abstract Article PDF–1.9M

Select item 619722118.

Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy

Khun Zaw Latt, Kenjiro Honda, Myo Thiri, Yuki Hitomi, Yosuke Omae, Hiromi Sawai, Yosuke Kawai, Shunsuke Teraguchi, Kazuko Ueno, Masao Nagasaki, Akihiko Mabuchi, Hajime Kaga, Atsushi Komatsuda, Katsushi Tokunaga, Eisei Noiri

Sci Rep. 2018; 8: 15576. Published online 2018 Oct 22. doi: 10.1038/s41598-018-33612-7