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Select item 109533231.

Association between antibiotic use during early life and early‐onset colorectal cancer risk overall and according to polygenic risk and FUT2 genotypes

Fangyuan Jiang, Daniel Boakye, Jing Sun, Lijuan Wang, Lili Yu, Xuan Zhou, Jianhui Zhao, Zilong Bian, Peige Song, Yazhou He, Yingshuang Zhu, Jie Chen, Shuai Yuan, Mingyang Song, Susanna C. Larsson, Edward L Giovannucci, Evropi Theodoratou, Kefeng Ding, Xue Li

Int J Cancer. 2023 Nov 1; 153(9): 1602–1611. Published online 2023 Jul 28. doi: 10.1002/ijc.34648

PMCID:: PMC10953323

Abstract Article PDF–865K

Select item 105279502.

Relationship between ABO blood group alleles and pancreatic cancer is modulated by secretor (FUT2) genotype, but not Lewis antigen (FUT3) genotype

Jihye Kim, Chen Yuan, Laufey T. Amundadottir, Brian M. Wolpin, Pancreatic Cancer Cohort Consortium (PanScan), Alison P. Klein, Pancreatic Cancer Case-Control Consortium (PanC4), Harvey A. Risch, Peter Kraft

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2024 Mar 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2023 Sep 1; 32(9): 1242–1248. doi: 10.1158/1055-9965.EPI-23-0009

PMCID:: PMC10527950

Abstract Article PDF–221K

Select item 104994823.

Genotype Frequencies of 50 Polymorphisms for 241 Japanese Non-cancer Patients

Nobuyuki Hamajima, Toshiko Saito, Keitaro Matsuo, Takashi Suzuki, Tsuneya Nakamura, Akio Matsuura, Katashi Okuma, Kazuo Tajima

J Epidemiol. 2002; 12(3): 229–236. Published online 2007 Nov 30. doi: 10.2188/jea.12.229

PMCID:: PMC10499482

Abstract Article PDF–588K

Select item 99110904.

FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β-catenin pathway

Peng Liu, Jingyu Liu, Mengyang Ding, Yijing Liu, Yue Zhang, Xiaoming Chen, Zhenxu Zhou

Int J Oncol. 2023 Mar; 62(3): 35. Published online 2023 Jan 31. doi: 10.3892/ijo.2023.5483

PMCID:: PMC9911090

Abstract Article PDF–4.0M

Select item 99020465.

Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media

Regie Lyn P. Santos-Cortez, Kimberly Mae C. Ong, Angeli Carlos-Hiceta, Ma. Leah C. Tantoco, Talitha Karisse L. Yarza, Ma. Luz San Agustin, Melquiadesa Pedro, Teresa Luisa G. Cruz, Eva Maria Cutiongco-de la Paz, Generoso T. Abes, Erasmo Gonzalo d.V. Llanes, Abner L. Chan, Charlotte M. Chiong, Maria Rina T. Reyes-Quintos

Genet Test Mol Biomarkers. January 2023; 27(1): 12–17. Published online 2023 Jan 31. doi: 10.1089/gtmb.2022.0171

PMCID:: PMC9902046

Abstract Article PDF–218K

Select item 98664116.

Gut Microbiome Composition and Metabolic Capacity Differ by FUT2 Secretor Status in Exclusively Breastfed Infants

Alexander W. Thorman, Grace Adkins, Shannon C. Conrey, Allison R. Burrell, Ying Yu, Brendon White, Rachel Burke, David Haslam, Daniel C. Payne, Mary A. Staat, Ardythe L. Morrow, David S. Newburg

Nutrients. 2023 Jan; 15(2): 471. Published online 2023 Jan 16. doi: 10.3390/nu15020471

PMCID:: PMC9866411

Abstract Article PDF–1.1M

Select item 97769187.

FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells

Yuqi Zhang, Enze Yao, Yijing Liu, Yining Zhang, Mengyang Ding, Jingyu Liu, Xiaoming Chen, Sairong Fan

Cells. 2022 Dec; 11(24): 4031. Published online 2022 Dec 13. doi: 10.3390/cells11244031

PMCID:: PMC9776918

Abstract Article PDF–7.3M

Select item 96371278.

Maternal and child FUT2 and FUT3 status demonstrate relationship with gut health, body composition and growth of children in Bangladesh

Md. Amran Gazi, Shah Mohammad Fahim, Md. Mehedi Hasan, Farzana Hossaini, Md. Ashraful Alam, Md. Shabab Hossain, Md. Daluwar Hossain, Subhasish Das, Rashidul Haque, Mustafa Mahfuz, Tahmeed Ahmed

Sci Rep. 2022; 12: 18764. Published online 2022 Nov 5. doi: 10.1038/s41598-022-23616-9

PMCID:: PMC9637127

Abstract Article PDF–1.0M

Select item 92594969.

Whole-genome sequencing reveals host factors underlying critical COVID-19

Athanasios Kousathanas, Erola Pairo-Castineira, Konrad Rawlik, Alex Stuckey, Christopher A. Odhams, Susan Walker, Clark D. Russell, Tomas Malinauskas, Yang Wu, Jonathan Millar, Xia Shen, Katherine S. Elliott, Fiona Griffiths, Wilna Oosthuyzen, Kirstie Morrice, Sean Keating, Bo Wang, Daniel Rhodes, Lucija Klaric, Marie Zechner, Nick Parkinson, Afshan Siddiq, Peter Goddard, Sally Donovan, David Maslove, Alistair Nichol, Malcolm G. Semple, Tala Zainy, Fiona Maleady-Crowe, Linda Todd, Shahla Salehi, Julian Knight, Greg Elgar, Georgia Chan, Prabhu Arumugam, Christine Patch, Augusto Rendon, David Bentley, Clare Kingsley, Jack A. Kosmicki, Julie E. Horowitz, Aris Baras, Goncalo R. Abecasis, Manuel A. R. Ferreira, Anne Justice, Tooraj Mirshahi, Matthew Oetjens, Daniel J. Rader, Marylyn D. Ritchie, Anurag Verma, Tom A. Fowler, Manu Shankar-Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Danny McAuley, Hugh Montgomery, Peter J. M. Openshaw, Paul Elliott, Timothy Walsh, Albert Tenesa, GenOMICC investigators, 23andMe investigators, COVID-19 Human Genetics Initiative, Angie Fawkes, Lee Murphy, Kathy Rowan, Chris P. Ponting, Veronique Vitart, James F. Wilson, Jian Yang, Andrew D. Bretherick, Richard H. Scott, Sara Clohisey Hendry, Loukas Moutsianas, Andy Law, Mark J. Caulfield, J. Kenneth Baillie

Nature. 2022; 607(7917): 97–103. Published online 2022 Mar 7. doi: 10.1038/s41586-022-04576-6

PMCID:: PMC9259496

Abstract Article PDF–8.1M

Select item 879832410.

The FUT2 Variant c.461G>A (p.Trp154*) Is Associated With Differentially Expressed Genes and Nasopharyngeal Microbiota Shifts in Patients With Otitis Media

Christina L. Elling, Melissa A. Scholes, Sven-Olrik Streubel, Eric D. Larson, Todd M. Wine, Tori C. Bootpetch, Patricia J. Yoon, Jennifer M. Kofonow, Samuel P. Gubbels, Stephen P. Cass, Charles E. Robertson, Herman A. Jenkins, Jeremy D. Prager, Daniel N. Frank, Kenny H. Chan, Norman R. Friedman, Allen F. Ryan, Regie Lyn P. Santos-Cortez

Front Cell Infect Microbiol. 2021; 11: 798246. Published online 2022 Jan 14. doi: 10.3389/fcimb.2021.798246

PMCID:: PMC8798324

Abstract Article PDF–5.3M

Select item 829843511.

Rapid detection of phenotypes Bombay se^del and nonsecretor rs200157007 SNP (302C > T) by real-time PCR-based methods

Mikiko Soejima, Yoshiro Koda

Sci Rep. 2021; 11: 14996. Published online 2021 Jul 22. doi: 10.1038/s41598-021-94659-7

PMCID:: PMC8298435

Abstract Article PDF–2.1M

Select item 786263312.

Survey and characterization of nonfunctional alleles of FUT2 in a database

Mikiko Soejima, Yoshiro Koda

Sci Rep. 2021; 11: 3186. Published online 2021 Feb 4. doi: 10.1038/s41598-021-82895-w

PMCID:: PMC7862633

Abstract Article PDF–1.6M

Select item 774457613.

FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

Tarunveer S. Ahluwalia, Anders U. Eliasen, Astrid Sevelsted, Casper-Emil T. Pedersen, Jakob Stokholm, Bo Chawes, Jette Bork-Jensen, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Amitabh Sharma, Scott T. Weiss, Michael D. Evans, Daniel J. Jackson, Andreanne Morin, Karen A. Krogfelt, Susanne Schjørring, Preben B. Mortensen, David M. Hougaard, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, Ole Mors, Merete Nordentoft, Anders D. Børglum, Thomas Werge, Esben Agerbo, James E. Gern, Robert F. Lemanske, Jr., Carole Ober, Anders G. Pedersen, Hans Bisgaard, Klaus Bønnelykke

Nat Commun. 2020; 11: 6398. Published online 2020 Dec 16. doi: 10.1038/s41467-020-19814-6

PMCID:: PMC7744576

Abstract Article PDF–1.2M

Select item 760099014.

FUT2, Secretor Status and FUT3 Polymorphisms of Children with Acute Diarrhea Infected with Rotavirus and Norovirus in Brazil

Marco André Loureiro Tonini, Débora Maria Pires Gonçalves Barreira, Luciana Bueno de Freitas Santolin, Lays Paula Bondi Volpini, José Paulo Gagliardi Leite, Béatrice Le Moullac-Vaidye, Jacques Le Pendu, Liliana Cruz Spano

Viruses. 2020 Oct; 12(10): 1084. Published online 2020 Sep 25. doi: 10.3390/v12101084

PMCID:: PMC7600990

Abstract Article PDF–322K

Select item 755116215.

Can the FUT 2 Gene Variant Have an Effect on the Body Weight of Patients Undergoing Bariatric Surgery?—Preliminary, Exploratory Study

Natalia Komorniak, Alexandra Martynova-Van Kley, Armen Nalian, Wiktoria Wardziukiewicz, Karolina Skonieczna-Żydecka, Daniel Styburski, Joanna Palma, Bartosz Kowalewski, Krzysztof Kaseja, Ewa Stachowska

Nutrients. 2020 Sep; 12(9): 2621. Published online 2020 Aug 28. doi: 10.3390/nu12092621

PMCID:: PMC7551162

Abstract Article PDF–4.1M

Select item 707847116.

Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

Kei Haga, Khalil Ettayebi, Victoria R. Tenge, Umesh C. Karandikar, Miranda A. Lewis, Shih-Ching Lin, Frederick H. Neill, B. Vijayalakshmi Ayyar, Xi-Lei Zeng, Göran Larson, Sasirekha Ramani, Robert L. Atmar, Mary K. Estes

mBio. 2020 Mar-Apr; 11(2): e00251-20. Published online 2020 Mar 17. doi: 10.1128/mBio.00251-20

PMCID:: PMC7078471

Abstract Article PDF–1.1M

Select item 668750417.

FUT2 gene variants and reported respiratory and gastrointestinal illnesses during infancy

Sheila J. Barton, Robert Murray, Karen A. Lillycrop, Hazel M Inskip, Nicholas C Harvey, Cyrus Cooper, Neerja Karnani, Irma Silva Zolezzi, Norbert Sprenger, Keith M. Godfrey, Aristea Binia

J Infect Dis. Author manuscript; available in PMC 2019 Aug 15.

Published in final edited form as: J Infect Dis. 2019 Feb 15; 219(5): 836–843. Published online 2018 Oct 30. doi: 10.1093/infdis/jiy582

PMCID:: PMC6687504

Abstract Article PDF–812K

Select item 633800718.

Association of Fucosyltransferase 2 Gene Variant with Inflammatory Bowel Diseases: A Meta-Analysis

Feng Zhou, Qin Zhu, Pei-Fen Zheng, Yu-Liang Feng

Med Sci Monit. 2019; 25: 184–192. Published online 2019 Jan 7. doi: 10.12659/MSM.911857

PMCID:: PMC6338007

Abstract Article PDF–677K

Select item 621965219.

FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects

Williams Turpin, Larbi Bedrani, Osvaldo Espin-Garcia, Wei Xu, Mark S. Silverberg, Michelle I. Smith, David S. Guttman, Anne Griffiths, Paul Moayyedi, Remo Panaccione, Hien Huynh, Hillary Steinhart, Guy Aumais, Konstantin Shestopaloff, Levinus A. Dieleman, Dan Turner, Andrew D. Paterson, Kenneth Croitoru

Gut Microbes. 2018; 9(4): 357–368. Published online 2018 Apr 27. doi: 10.1080/19490976.2018.1445956

PMCID:: PMC6219652

Abstract Article PDF–960K

Select item 621775920.

FUT2 Variants Confer Susceptibility to Familial Otitis Media

Regie Lyn P. Santos-Cortez, Charlotte M. Chiong, Daniel N. Frank, Allen F. Ryan, Arnaud P.J. Giese, Tori Bootpetch Roberts, Kathleen A. Daly, Matthew J. Steritz, Wasyl Szeremeta, Melquiadesa Pedro, Harold Pine, Talitha Karisse L. Yarza, Melissa A. Scholes, Erasmo Gonzalo d.V. Llanes, Saira Yousaf, Norman Friedman, Ma. Leah C. Tantoco, Todd M. Wine, Patrick John Labra, Jeanne Benoit, Amanda G. Ruiz, Rhodieleen Anne R. de la Cruz, Christopher Greenlee, Ayesha Yousaf, Jonathan Cardwell, Rachelle Marie A. Nonato, Dylan Ray, Kimberly Mae C. Ong, Edward So, Charles E. Robertson, Jordyn Dinwiddie, Sheryl Mae Lagrana-Villagracia, University of Washington Center for Mendelian Genomics (UWCMG), Samuel P. Gubbels, Rehan S. Shaikh, Stephen P. Cass, Elisabet Einarsdottir, Nanette R. Lee, David A. Schwartz, Teresa Luisa I. Gloria-Cruz, Michael J. Bamshad, Ivana V. Yang, Juha Kere, Generoso T. Abes, Jeremy D. Prager, Saima Riazuddin, Abner L. Chan, Patricia J. Yoon, Deborah A. Nickerson, Eva Maria Cutiongco-de la Paz, Sven-Olrik Streubel, Maria Rina T. Reyes-Quintos, Herman A. Jenkins, Petri Mattila, Kenny H. Chan, Karen L. Mohlke, Suzanne M. Leal, Lena Hafrén, Tasnee Chonmaitree, Michele M. Sale, Zubair M. Ahmed

Am J Hum Genet. 2018 Nov 1; 103(5): 679–690. Published online 2018 Oct 25. doi: 10.1016/j.ajhg.2018.09.010

PMCID:: PMC6217759

Abstract Article PDF–1.4M

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