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Select item 113036971.

A keratinocyte-adipocyte signaling loop is reprogrammed by loss of BTG3 to augment skin carcinogenesis

Yu-Che Cheng, Jack Dalit Acedera, Yi-Ju Li, Sheau-Yann Shieh

Cell Death Differ. 2024 Aug; 31(8): 970–982. Published online 2024 May 7. doi: 10.1038/s41418-024-01304-7

PMCID:: PMC11303697

Abstract Article PDF–4.9M

Select item 93485762.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 89740014.

Long non-coding RNA cancer susceptibility candidate 2 regulates the function of human fibroblast-like synoviocytes via the microRNA-18a-5p/B-cell translocation gene 3 signaling axis in rheumatoid arthritis

Zhiqin Ye, Lu Wei, Xietian Yin, Huiling Li, Guifu Qin, Siqi Li, Tingting Peng, Bo Liu, Shichao Zhao, Qin Zhuo

Bioengineered. 2022; 13(2): 3240–3250. Published online 2022 Jan 19. doi: 10.1080/21655979.2021.2022075

PMCID:: PMC8974001

Abstract Article PDF–2.4M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77328376.

Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation

Yu-Che Cheng, Hsin-Yi Chiang, Shang-Jung Cheng, Hung-Wei Chang, Yi-Ju Li, Sheau-Yann Shieh

Cell Death Dis. 2020 Dec; 11(12): 1046. Published online 2020 Dec 11. doi: 10.1038/s41419-020-03248-5

PMCID:: PMC7732837

Abstract Article PDF–2.6M

Select item 74273277.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 60420068.

Methylation-Mediated Downregulation of the B-Cell Translocation Gene 3 (BTG3) in Breast Cancer Cells

Jingwei Yu, Yingsha Zhang, Zhongxia Qi, Daniel Kurtycz, Guido Vacano, David Patterson

Gene Expr. 2008; 14(3): 173–182. Published online 2018 Jul 12.

PMCID:: PMC6042006

Abstract Article PDF–3.3M

Select item 60034599.

Deubiquitinating enzyme USP3 controls CHK1 chromatin association and activation

Yu-Che Cheng, Sheau-Yann Shieh

Proc Natl Acad Sci U S A. 2018 May 22; 115(21): 5546–5551. Published online 2018 May 7. doi: 10.1073/pnas.1719856115

PMCID:: PMC6003459

Abstract Article PDF–1.5M

Select item 592675310.

Association of ANA, a Member of the Antiproliferative Tob Family Proteins, with a Cafl Component of the CCR4 Transcriptional Regulatory Complex

Yutaka Yoshida, Eri Hosoda, Takahisa Nakamura, Tadashi Yamamoto

Jpn J Cancer Res. 2001 Jun; 92(6): 592–596. doi: 10.1111/j.1349-7006.2001.tb01135.x

PMCID:: PMC5926753

Summary PDF–1.6M

Select item 579482311.

The function of BTG3 in colorectal cancer cells and its possible signaling pathway

Chi Lv, Heling Wang, Yuxin Tong, Hongzhuan Yin, Dalu Wang, Zhaopeng Yan, Yichao Liang, Di Wu, Qi Su

J Cancer Res Clin Oncol. 2018; 144(2): 295–308. Published online 2017 Dec 21. doi: 10.1007/s00432-017-2561-9

PMCID:: PMC5794823

Abstract Article PDF–12M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539233113.

The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study

Hua-Chuan Zheng, Hao-Yu He, Ji-Cheng Wu, Jing Li, Shuang Zhao, Gui-Feng Zhao, Hua-Mao Jiang, Xue-Wen Yu, Zhi-Jie Li

Oncotarget. 2017 Mar 14; 8(11): 18322–18336. Published online 2017 Feb 17. doi: 10.18632/oncotarget.15438

PMCID:: PMC5392331

Abstract Article PDF–11M

Select item 535041414.

Lack of Clinical Relevance of ANA and ASMA Positivity in Patients with Liver Transplantation without a History of Autoimmune Diseases

Lucienne Pellegrini, Gianpaolo Parrilli, Antonella Santonicola, Luigi Cinquanta, Cesare Caputo, Carolina Ciacci, Fabiana Zingone

Biomed Res Int. 2017; 2017: 2456916. Published online 2017 Feb 27. doi: 10.1155/2017/2456916

PMCID:: PMC5350414

Abstract Article PDF–489K

Select item 466974815.

Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT

Y-C Cheng, P-H Chen, H-Y Chiang, C-S Suen, M-J Hwang, T-Y Lin, H-C Yang, W-C Lin, P-L Lai, S-Y Shieh

Cell Death Dis. 2015 Jan; 6(1): e1584. Published online 2015 Jan 8. doi: 10.1038/cddis.2014.550

PMCID:: PMC4669748

Abstract Article PDF–3.7M

Select item 463732516.

The roles of BTG3 expression in gastric cancer: a potential marker for carcinogenesis and a target molecule for gene therapy

Wen-feng Gou, Xue-feng Yang, Dao-fu Shen, Shuang Zhao, Yun-peng Liu, Hong-zhi Sun, Yasuo Takano, Rong-jian Su, Jun-sheng Luo, Hua-chuan Zheng

Oncotarget. 2015 Aug 14; 6(23): 19841–19867. Published online 2015 Mar 30. doi: 10.18632/oncotarget.3734

PMCID:: PMC4637325

Abstract Article PDF–18M

Select item 461721117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 378570518.

Decreased expression of BTG3 was linked to carcinogenesis, aggressiveness, and prognosis of ovarian carcinoma

Boya Deng, Yang Zhao, Wenfeng Gou, Shuo Chen, Xiaoyun Mao, Yasuo Takano, Huachuan Zheng

Tumour Biol. 2013 Oct; 34(5): 2617–2624. Published online 2013 May 9. doi: 10.1007/s13277-013-0811-2

PMCID:: PMC3785705

Abstract Article PDF–427K

Select item 362530119.

Candidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the checkpoint kinase CHK1

Yu-Che Cheng, Tsong-Yu Lin, Sheau-Yann Shieh

Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15): 5993–5998. Published online 2013 Mar 26. doi: 10.1073/pnas.1220635110

PMCID:: PMC3625301

Abstract Article PDF–935K

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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