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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99504473.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 92792854.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91052355.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 90588366.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 83145477.

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5

PMCID:: PMC8314547

Abstract Article PDF–3.7M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81639869.

Mitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion

N. Vishnu, A. Hamilton, A. Bagge, A. Wernersson, E. Cowan, H. Barnard, Y. Sancak, K.J. Kamer, P. Spégel, M. Fex, A. Tengholm, V.K. Mootha, D.G. Nicholls, H. Mulder

Mol Metab. 2021 Sep; 51: 101239. Published online 2021 Apr 28. doi: 10.1016/j.molmet.2021.101239

PMCID:: PMC8163986

Abstract Article PDF–2.2M

Select item 789587110.

Structure of intact human MCU supercomplex with the auxiliary MICU subunits

Wei Zhuo, Heng Zhou, Runyu Guo, Jingbo Yi, Laixing Zhang, Lei Yu, Yinqiang Sui, Wenwen Zeng, Peiyi Wang, Maojun Yang

Protein Cell. 2021 Mar; 12(3): 220–229. Published online 2020 Aug 30. doi: 10.1007/s13238-020-00776-w

PMCID:: PMC7895871

Article PDF–2.5M

Select item 776445111.

Mechanisms of EMRE-Dependent MCU Opening in the Mitochondrial Calcium Uniporter Complex

Anna M. Van Keuren, Chen-Wei Tsai, Enrique Balderas, Madison X. Rodriguez, Dipayan Chaudhuri, Ming-Feng Tsai

Cell Rep. Author manuscript; available in PMC 2020 Dec 26.

Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108486. doi: 10.1016/j.celrep.2020.108486

PMCID:: PMC7764451

Abstract Article PDF–1.3M

Select item 754443112.

Structure and mechanism of the mitochondrial Ca²⁺ uniporter holocomplex

Minrui Fan, Jinru Zhang, Chen-Wei Tsai, Benjamin J. Orlando, Madison Rodriguez, Yan Xu, Maofu Liao, Ming-Feng Tsai, Liang Feng

Nature. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nature. 2020 Jun; 582(7810): 129–133. Published online 2020 May 20. doi: 10.1038/s41586-020-2309-6

PMCID:: PMC7544431

Abstract Article PDF–7.2M

Select item 752792213.

The structure of the MICU1‐MICU2 complex unveils the regulation of the mitochondrial calcium uniporter

Wenping Wu, Qingya Shen, Ruiling Zhang, Zhiyu Qiu, Youjun Wang, Jimin Zheng, Zongchao Jia

EMBO J. 2020 Oct 1; 39(19): e104285. Published online 2020 Aug 13. doi: 10.15252/embj.2019104285

PMCID:: PMC7527922

Abstract Article PDF–4.0M

Select item 744249014.

Structural insights into the Ca²⁺-dependent gating of the human mitochondrial calcium uniporter

Yan Wang, Yan Han, Ji She, Nam X Nguyen, Vamsi K Mootha, Xiao-chen Bai, Youxing Jiang

eLife. 2020; 9: e60513. Published online 2020 Aug 7. doi: 10.7554/eLife.60513

PMCID:: PMC7442490

Abstract Article PDF–5.7M

Select item 743444515.

Structures reveal gatekeeping of the mitochondrial Ca²⁺ uniporter by MICU1-MICU2

Chongyuan Wang, Agata Jacewicz, Bryce D Delgado, Rozbeh Baradaran, Stephen Barstow Long

eLife. 2020; 9: e59991. Published online 2020 Jul 15. doi: 10.7554/eLife.59991

PMCID:: PMC7434445

Abstract Article PDF–2.9M

Select item 732206716.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 705537017.

Structure of the MICU1–MICU2 heterodimer provides insights into the gatekeeping threshold shift

Jongseo Park, Youngjin Lee, Taein Park, Jung Youn Kang, Sang A Mun, Minwoo Jin, Jihyeong Yang, Soo Hyun Eom

IUCrJ. 2020 Mar 1; 7(Pt 2): 355–365. Published online 2020 Feb 27. doi: 10.1107/S2052252520001840

PMCID:: PMC7055370

Abstract Article PDF–1.8M

Select item 699656018.

MCUB regulates the molecular composition of the mitochondrial calcium uniporter channel to limit mitochondrial calcium overload during stress

Jonathan P. Lambert, Timothy S. Luongo, Dhanendra Tomar, Pooja Jadiya, Erhe Gao, Xueqian Zhang, Anna Maria Lucchese, Devin W. Kolmetzky, Neil S. Shah, John W. Elrod

Circulation. Author manuscript; available in PMC 2020 Nov 19.

Published in final edited form as: Circulation. 2019 Nov 19; 140(21): 1720–1733. Published online 2019 Sep 19. doi: 10.1161/CIRCULATIONAHA.118.037968

PMCID:: PMC6996560

Abstract Article PDF–1.6M

Select item 677303019.

DCAMKL1 Encodes a Protein Kinase with Homology to Doublecortin that Regulates Microtubule Polymerization

Peter T. Lin, Joseph G. Gleeson, Joseph C. Corbo, Lisa Flanagan, Christopher A. Walsh

J Neurosci. 2000 Dec 15; 20(24): 9152–9161. doi: 10.1523/JNEUROSCI.20-24-09152.2000

PMCID:: PMC6773030

Abstract Article PDF–926K

Select item 674682220.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

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