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Select item 107001381.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106679232.

Methionine Restriction Impairs Degradation of a Protein that Aberrantly Engages the Endoplasmic Reticulum Translocon

Avery M. Runnebohm, Christopher J. Indovina, Samantha M. Turk, Connor G. Bailey, Cade J. Orchard, Lauren Wade, Danielle L. Overton, Brian J. Snow, Eric M. Rubenstein

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.001021. Published online 2023 Nov 9. doi: 10.17912/micropub.biology.001021

PMCID:: PMC10667923

Abstract Article PDF–906K

Select item 101039813.

Deep mutational scanning highlights a new role for cytosolic regions in Hrd1 function

Brian G. Peterson, Jiwon Hwang, Jennifer E. Russ, Jeremy Schroeder, Peter L. Freddolino, Ryan D. Baldridge

Version 1. bioRxiv. Preprint. 2023 Apr 3. doi: 10.1101/2023.04.03.535444

Published in:: Cell Rep. 2023 Nov 28; 42(11): 113451.

PMCID:: PMC10103981

Abstract Article PDF–5.6M

Select item 98945554.

Yeast derlin Dfm1 employs a chaperone-like function to resolve misfolded membrane protein stress

Rachel Kandel, Jasmine Jung, Della Syau, Tiffany Kuo, Livia Songster, Casey Horn, Claire Chapman, Analine Aguayo, Sascha Duttke, Christopher Benner, Sonya E. Neal

PLoS Biol. 2023 Jan; 21(1): e3001950. Published online 2023 Jan 23. doi: 10.1371/journal.pbio.3001950

PMCID:: PMC9894555

Abstract Article PDF–3.3M

Select item 94784035.

Disulfide-crosslink analysis of the ubiquitin ligase Hrd1 complex during endoplasmic reticulum-associated protein degradation

Rudolf Pisa, Tom A. Rapoport

J Biol Chem. 2022 Sep; 298(9): 102373. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102373

PMCID:: PMC9478403

Abstract Article PDF–2.8M

Select item 92098116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 85769177.

Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis

Emmanuel T. Nsamba, Abesh Bera, Michael Costanzo, Charles Boone, Mohan L. Gupta, Jr.

J Cell Biol. 2021 Dec 6; 220(12): e202010155. Published online 2021 Nov 5. doi: 10.1083/jcb.202010155

PMCID:: PMC8576917

Abstract Article PDF–7.4M

Select item 78611328.

Loss of protein quality control gene UBR1 sensitizes Saccharomyces cerevisiae to the aminoglycoside hygromycin B

Avery M. Runnebohm, Melissa D. Evans, Adam E. Richardson, Samantha M. Turk, James B. Olesen, Philip J. Smaldino, Eric M. Rubenstein

Fine Focus. Author manuscript; available in PMC 2021 Feb 4.

Published in final edited form as: Fine Focus. 2020 Oct 26; 6(1): 76–83. doi: 10.33043/FF.6.1.76-83

PMCID:: PMC7861132

Abstract Article PDF–102K

Select item 77452599.

A Systematic Protein Turnover Map for Decoding Protein Degradation

Romain Christiano, Henning Arlt, Sonja Kabatnik, Niklas Mejhert, Zon Weng Lai, Robert V. Farese, Jr., Tobias C. Walther

Cell Rep. Author manuscript; available in PMC 2020 Dec 17.

Published in final edited form as: Cell Rep. 2020 Nov 10; 33(6): 108378. doi: 10.1016/j.celrep.2020.108378

PMCID:: PMC7745259

Abstract Article PDF–1.1M

Select item 774405010.

Characterization of constitutive ER-phagy of excess membrane proteins

Zhanna Lipatova, Valeriya Gyurkovska, Sarah F. Zhao, Nava Segev

PLoS Genet. 2020 Dec; 16(12): e1009255. Published online 2020 Dec 4. doi: 10.1371/journal.pgen.1009255

PMCID:: PMC7744050

Abstract Article PDF–4.0M

Select item 771875111.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 768101712.

Overlapping function of Hrd1 and Ste24 in translocon quality control provides robust channel surveillance

Avery M. Runnebohm, Kyle A. Richards, Courtney Broshar Irelan, Samantha M. Turk, Halie E. Vitali, Christopher J. Indovina, Eric M. Rubenstein

J Biol Chem. 2020 Nov 20; 295(47): 16113–16120. Published online 2020 Oct 8. doi: 10.1074/jbc.AC120.016191

PMCID:: PMC7681017

Abstract Article PDF–1.4M

Select item 766788613.

Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly‐ubiquitylation

Christian Lips, Tobias Ritterhoff, Annika Weber, Maria K Janowska, Mandy Mustroph, Thomas Sommer, Rachel E Klevit

EMBO J. 2020 Nov 16; 39(22): e104863. Published online 2020 Oct 5. doi: 10.15252/embj.2020104863

PMCID:: PMC7667886

Abstract Article PDF–1.5M

Select item 766412214.

The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation

Teresa M. Buck, Xuemei Zeng, Pamela S. Cantrell, Richard T. Cattley, Zikri Hasanbasri, Megan E. Yates, Diep Nguyen, Nathan A. Yates, Jeffrey L. Brodsky

Mol Cell Proteomics. 2020 Nov; 19(11): 1896–1909. Published online 2020 Aug 31. doi: 10.1074/mcp.RA120.002050

PMCID:: PMC7664122

Abstract Article PDF–1.2M

Select item 753061015.

Gene Loss Predictably Drives Evolutionary Adaptation

Jana Helsen, Karin Voordeckers, Laura Vanderwaeren, Toon Santermans, Maria Tsontaki, Kevin J Verstrepen, Rob Jelier

Mol Biol Evol. 2020 Oct; 37(10): 2989–3002. Published online 2020 Jul 13. doi: 10.1093/molbev/msaa172

PMCID:: PMC7530610

Abstract Article PDF–1.8M

Select item 738055316.

Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex

Xudong Wu, Marc Siggel, Sergey Ovchinnikov, Wei Mi, Vladimir Svetlov, Evgeny Nudler, Maofu Liao, Gerhard Hummer, Tom A. Rapoport

Science. Author manuscript; available in PMC 2020 Jul 24.

Published in final edited form as: Science. 2020 Apr 24; 368(6489): eaaz2449. doi: 10.1126/science.aaz2449

PMCID:: PMC7380553

Abstract Article PDF–2.0M

Select item 731785217.

Size‐dependent secretory protein reflux into the cytosol in association with acute endoplasmic reticulum stress

Patrick Lajoie, Erik L. Snapp

Traffic. 2020 Jun; 21(6): 419–429. Published online 2020 Apr 13. doi: 10.1111/tra.12729

PMCID:: PMC7317852

Abstract Article PDF–2.7M

Select item 703181518.

TOM1 confers resistance to the aminoglycoside hygromycin B in Saccharomyces cerevisiae

Julia M Niekamp, Melissa D Evans, Abigail R Scott, Philip J Smaldino, Eric M Rubenstein

MicroPubl Biol. Author manuscript; available in PMC 2020 Feb 20.

Published in final edited form as: MicroPubl Biol. 2019; 2019: 10.17912/micropub.biology.000193. Published online 2019 Dec 6.

PMCID:: PMC7031815

Article PDF–396K

Select item 692646319.

Endoplasmic reticulum stress differentially inhibits endoplasmic reticulum and inner nuclear membrane protein quality control degradation pathways

Bryce W. Buchanan, Adrian B. Mehrtash, Courtney L. Broshar, Avery M. Runnebohm, Brian J. Snow, Laura N. Scanameo, Mark Hochstrasser, Eric M. Rubenstein

J Biol Chem. 2019 Dec 20; 294(51): 19814–19830. Published online 2019 Nov 13. doi: 10.1074/jbc.RA119.010295