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Items: 1 to 20 of 31

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Regulation of DNA damage and transcriptional output in the vasculature through a cytoglobin-HMGB2 axis
Clinton Mathai, Frances Jourd'heuil, Le Gia Cat Pham, Kurrim Gilliard, Dennis Howard, Joseph Balnis, Ariel Jaitovich, Sridar V. Chittur, Mark Rilley, Ruben Peredo-Wende, Ibrahim Ammoura, Sandra J. Shin, Margarida Barroso, Jonathan Barra, Evgenia Shishkova, Joshua J. Coon, Reynold I. Lopez-Soler, David Jourd'heuil
Redox Biol. 2023 Sep; 65: 102838. Published online 2023 Aug 9. doi: 10.1016/j.redox.2023.102838
PMCID:
PMC10428073
AbstractArticlePDF–10M
3.
Nitric Oxide Derived from Cytoglobin-Deficient Hepatic Stellate Cells Causes Suppression of Cytochrome c Oxidase Activity in Hepatocytes
Yoshinori Okina, Misako Sato-Matsubara, Yasutoshi Kido, Hayato Urushima, Atsuko Daikoku, Chiho Kadono, Yu Nakagama, Yuko Nitahara, Truong Huu Hoang, Le Thi Thanh Thuy, Tsutomu Matsubara, Naoko Ohtani, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada
Antioxid Redox Signal. March 2023; 38(7-9): 463–479. Published online 2023 Mar 16. doi: 10.1089/ars.2021.0279
PMCID:
PMC10025843
AbstractArticlePDF–1.2M
4.
Cytoglobin has potent superoxide dismutase function
Jay L. Zweier, Craig Hemann, Tapan Kundu, Mohamed G. Ewees, Sahar A. Khaleel, Alexandre Samouilov, Govindasamy Ilangovan, Mohamed A. El-Mahdy
Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2105053118. Published online 2021 Dec 20. doi: 10.1073/pnas.2105053118
PMCID:
PMC8719900
AbstractArticlePDF–1.7M
5.
Defining the reducing system of the NO dioxygenase cytoglobin in vascular smooth muscle cells and its critical role in regulating cellular NO decay
Govindasamy Ilangovan, Sahar A. Khaleel, Tapan Kundu, Craig Hemann, Mohamed A. El-Mahdy, Jay L. Zweier
J Biol Chem. 2021 Jan-Jun; 296: 100196. Published online 2020 Dec 20. doi: 10.1074/jbc.RA120.016394
PMCID:
PMC7948950
AbstractArticlePDF–1.5M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Binary Fate Choice between Closely Related Interneuronal Types Is Determined by A Fezf1-Dependent Postmitotic Transcriptional Switch
Yi-Rong Peng, Rebecca E. James, Wenjun Yan, Jeremy N. Kay, Alex L. Kolodkin, Joshua R. Sanes
Neuron. Author manuscript; available in PMC 2021 Feb 5.
Published in final edited form as: Neuron. 2020 Feb 5; 105(3): 464–474.e6. Published online 2019 Dec 4. doi: 10.1016/j.neuron.2019.11.002
PMCID:
PMC7007373
AbstractArticlePDF–2.2M
8.
Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice
Young Sam Kwon, Addy Tham, Antonio Jacobo Lopez, Sydney Edwards, Sean Woods, Jiajia Chen, Jenna Fortunato, Alejandra Quiroz, Seanne Javier, Ingrid Au, Maria Clarke, Devin Humpal, K. C. Kent Lloyd, Sara Thomasy, Christopher Murphy, Thomas M. Glaser, Ala Moshiri
Dev Biol. Author manuscript; available in PMC 2021 Feb 15.
Published in final edited form as: Dev Biol. 2020 Feb 15; 458(2): 141–152. Published online 2019 Oct 18. doi: 10.1016/j.ydbio.2019.10.013
PMCID:
PMC6995765
AbstractArticlePDF–2.4M
9.
Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
Yuga Teranishi, Tsutomu Matsubara, Kristopher W Krausz, Thi TT Le, Frank J Gonzalez, Katsutoshi Yoshizato, Kazuo Ikeda, Norifumi Kawada
Lab Invest. Author manuscript; available in PMC 2019 Jan 14.
Published in final edited form as: Lab Invest. 2015 May; 95(5): 515–524. Published online 2015 Feb 16. doi: 10.1038/labinvest.2015.29
PMCID:
PMC6331008
AbstractArticlePDF–969K
10.
Novel lymphoid enhancer‐binding factor 1‐cytoglobin axis promotes extravasation of osteosarcoma cells into the lungs
Mongkol Pongsuchart, Takahiro Kuchimaru, Sakiko Yonezawa, Diem Thi Phuong Tran, Nguyen The Kha, Ngoc Thi Hong Hoang, Tetsuya Kadonosono, Shinae Kizaka‐Kondoh
Cancer Sci. 2018 Sep; 109(9): 2746–2756. Published online 2018 Jul 24. doi: 10.1111/cas.13702
PMCID:
PMC6125443
AbstractArticlePDF–2.3M
11.
Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice
Mohammad Yassin, Hannelouise Kissow, Ben Vainer, Philomeena Daphne Joseph, Anders Hay-Schmidt, Jørgen Olsen, Anders Elm Pedersen
Sci Rep. 2018; 8: 6905. Published online 2018 May 2. doi: 10.1038/s41598-018-24728-x
PMCID:
PMC5931983
AbstractArticlePDF–2.9M
12.
The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling
Frances L. Jourd'heuil, Haiyan Xu, Timothy Reilly, Keneta McKellar, Chaymae El Alaoui, Julia Steppich, Yong Feng Liu, Wen Zhao, Roman Ginnan, David Conti, Reynold Lopez-Soler, Arif Asif, Rebecca K. Keller, John J. Schwarz, Le Thi Thanh Thuy, Norifumi Kawada, Xiaochun Long, Harold A. Singer, David Jourd'heuil
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Oct; 37(10): 1944–1955. Published online 2017 Aug 10. doi: 10.1161/ATVBAHA.117.309410
PMCID:
PMC5620122
AbstractArticlePDF–890K
13.
Impaired hypoxic tolerance in APP23 mice: a dysregulation of neuroprotective globin levels
Zoë P. Van Acker, Evi Luyckx, Wendy Van Leuven, Eva Geuens, Peter P. De Deyn, Debby Van Dam, Sylvia Dewilde
FEBS Lett. 2017 May; 591(10): 1321–1332. Published online 2017 May 2. doi: 10.1002/1873-3468.12651
PMCID:
PMC5518225
AbstractArticlePDF–1016K
14.
Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall
Xiaoping Liu, Mohamed A. El-Mahdy, James Boslett, Saradhadevi Varadharaj, Craig Hemann, Tamer M. Abdelghany, Raed S. Ismail, Sean C. Little, Danlei Zhou, Le Thi Thanh Thuy, Norifumi Kawada, Jay L. Zweier
Nat Commun. 2017; 8: 14807. Published online 2017 Apr 10. doi: 10.1038/ncomms14807
PMCID:
PMC5394235
AbstractArticlePDF–2.0M
15.
Possible Involvement of Nitric Oxide in Enhanced Liver Injury and Fibrogenesis during Cholestasis in Cytoglobin-deficient Mice
Tuong Thi Van Thuy, Le Thi Thanh Thuy, Katsutoshi Yoshizato, Norifumi Kawada
Sci Rep. 2017; 7: 41888. Published online 2017 Feb 3. doi: 10.1038/srep41888
PMCID:
PMC5291093
AbstractArticlePDF–3.2M
16.
Absence of cytoglobin promotes multiple organ abnormalities in aged mice
Le Thi Thanh Thuy, Tuong Thi Van Thuy, Yoshinari Matsumoto, Hoang Hai, Yoshihiro Ikura, Katsutoshi Yoshizato, Norifumi Kawada
Sci Rep. 2016; 6: 24990. Published online 2016 May 5. doi: 10.1038/srep24990
PMCID:
PMC4857093
AbstractArticlePDF–2.9M
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
18.
Cytoglobin Is a Stress-responsive Hemoprotein Expressed in the Developing and Adult Brain
Pradeep P.A. Mammen, John M. Shelton, Qiu Ye, Shane B. Kanatous, Amanda J. McGrath, James A. Richardson, Daniel J. Garry
J Histochem Cytochem. 2006 Dec; 54(12): 1349–1361. doi: 10.1369/jhc.6A7008.2006
PMCID:
PMC3958125
AbstractArticlePDF–779K
19.
Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration
Sarvjeet Singh, Diana C. Canseco, Shilpa M. Manda, John M. Shelton, Rajendra R. Chirumamilla, Sean C. Goetsch, Qiu Ye, Robert D. Gerard, Jay W. Schneider, James A. Richardson, Beverly A. Rothermel, Pradeep P. A. Mammen
Proc Natl Acad Sci U S A. 2014 Jan 7; 111(1): E129–E138. Published online 2013 Dec 23. doi: 10.1073/pnas.1314962111
PMCID:
PMC3890830
AbstractArticlePDF–1.7M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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