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Items: 1 to 20 of 55

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Differential Role of the RAC1-Binding Proteins FAM49b (CYRI-B) and CYFIP1 in Platelets
Dmitri Sisario, Markus Spindler, Katharina J. Ermer, Noah Grütz, Leo Nicolai, Florian Gaertner, Laura M. Machesky, Markus Bender
Cells. 2024 Feb; 13(4): 299. Published online 2024 Feb 6. doi: 10.3390/cells13040299
PMCID:
PMC10886774
AbstractArticlePDF–5.7M
3.
Overexpression of the autism candidate gene Cyfip1 pathologically enhances olivo-cerebellar signaling in mice
Silas E. Busch, Dana H. Simmons, Eric Gama, Xiaofei Du, Francesco Longo, Christopher M. Gomez, Eric Klann, Christian Hansel
Front Cell Neurosci. 2023; 17: 1219270. Published online 2023 Jul 20. doi: 10.3389/fncel.2023.1219270
PMCID:
PMC10399232
AbstractArticlePDF–3.4M
4.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
5.
Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity
Taro Chaya, Hiroshi Ishikane, Leah R Varner, Yuko Sugita, Yamato Maeda, Ryotaro Tsutsumi, Daisuke Motooka, Daisuke Okuzaki, Takahisa Furukawa
Hum Mol Genet. 2022 Feb 15; 31(4): 535–547. Published online 2021 Sep 11. doi: 10.1093/hmg/ddab268
PMCID:
PMC8863419
AbstractArticlePDF–1.8M
6.
CYFIP1 dosages exhibit divergent behavioral impact via diametric regulation of NMDAR complex translation in mouse models of psychiatric disorders
Nam-Shik Kim, Francisca Rojas Ringeling, Ying Zhou, Ha Nam Nguyen, Stephanie J. Temme, Yu-Ting Lin, Stephen Eacker, Valina L. Dawson, Ted M. Dawson, Bo Xiao, Kuei-sen Hsu, Stefan Canzar, Weidong Li, Paul Worley, Kimberly M. Christian, Ki-Jun Yoon, Hongjun Song, Guo-li Ming
Biol Psychiatry. Author manuscript; available in PMC 2023 Nov 15.
Published in final edited form as: Biol Psychiatry. 2022 Nov 15; 92(10): 815–826. Published online 2021 May 5. doi: 10.1016/j.biopsych.2021.04.023
PMCID:
PMC8568734
AbstractArticlePDF–2.6M
7.
Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms
Niels Haan, Laura J. Westacott, Jenny Carter, Michael J. Owen, William P. Gray, Jeremy Hall, Lawrence S. Wilkinson
Transl Psychiatry. 2021; 11: 313. Published online 2021 May 24. doi: 10.1038/s41398-021-01415-6
PMCID:
PMC8144403
AbstractArticlePDF–3.0M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Vascular surveillance by haptotactic blood platelets in inflammation and infection
Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner
Nat Commun. 2020; 11: 5778. Published online 2020 Nov 13. doi: 10.1038/s41467-020-19515-0
Correction in:
Nat Commun. 2022; 13: 4645.
PMCID:
PMC7666582
AbstractArticlePDF–6.8M
10.
Complex Interactions between Genes and Social Environment Cause Phenotypes Associated with Autism Spectrum Disorders in Mice
Monika Sledziowska, Shireene Kalbassi, Stéphane J. Baudouin
eNeuro. 2020 Jul-Aug; 7(4): ENEURO.0124-20.2020. Prepublished online 2020 Jul 15. Published online 2020 Aug 5. doi: 10.1523/ENEURO.0124-20.2020
PMCID:
PMC7418534
AbstractArticlePDF–2.3M
11.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
12.
Persistent Cyfip1 Expression Is Required to Maintain the Adult Subventricular Zone Neurogenic Niche
Christa Whelan Habela, Ki-Jun Yoon, Nam-Shik Kim, Arens Taga, Kassidy Bell, Dwight E. Bergles, Nicholas J. Maragakis, Guo-li Ming, Hongjun Song
J Neurosci. 2020 Mar 4; 40(10): 2015–2024. doi: 10.1523/JNEUROSCI.2249-19.2020
PMCID:
PMC7055134
AbstractArticlePDF–3.5M
13.
Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus
Yinhua Zhang, Hyae Rim Kang, Kihoon Han
Anim Cells Syst (Seoul) 2019; 23(6): 380–383. Published online 2019 Nov 24. doi: 10.1080/19768354.2019.1696406
PMCID:
PMC6913624
AbstractArticlePDF–1.0M
14.
Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex
Richard K. Babbs, Jacob A. Beierle, Qiu T. Ruan, Julia C. Kelliher, Melanie M. Chen, Ashley X. Feng, Stacey L. Kirkpatrick, Fabiola A. Benitez, Fred A. Rodriguez, Johanne J. Pierre, Jeya Anandakumar, Vivek Kumar, Megan K. Mulligan, Camron D. Bryant
G3 (Bethesda) 2019 Sep; 9(9): 3009–3022. Published online 2019 Jul 19. doi: 10.1534/g3.119.400470
PMCID:
PMC6723122
AbstractArticlePDF–1.8M
15.
The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour
Nuria Domínguez-Iturza, Adrian C. Lo, Disha Shah, Marcelo Armendáriz, Anna Vannelli, Valentina Mercaldo, Massimo Trusel, Ka Wan Li, Denise Gastaldo, Ana Rita Santos, Zsuzsanna Callaerts-Vegh, Rudi D’Hooge, Manuel Mameli, Annemie Van der Linden, August B. Smit, Tilmann Achsel, Claudia Bagni
Nat Commun. 2019; 10: 3454. Published online 2019 Aug 1. doi: 10.1038/s41467-019-11203-y
PMCID:
PMC6672001
AbstractArticlePDF–3.8M
16.
Cyfip1 Haploinsufficiency Does Not Alter GABAA Receptor δ-Subunit Expression and Tonic Inhibition in Dentate Gyrus PV+ Interneurons and Granule Cells
Simon Trent, Jeremy Hall, William M. Connelly, Adam C. Errington
eNeuro. 2019 May-Jun; 6(3): ENEURO.0364-18.2019. Prepublished online 2019 Jun 17. Published online 2019 Jun 28. doi: 10.1523/ENEURO.0364-18.2019
PMCID:
PMC6635810
AbstractArticlePDF–3.8M
17.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
18.
Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition
Elizabeth C. Davenport, Blanka R. Szulc, James Drew, James Taylor, Toby Morgan, Nathalie F. Higgs, Guillermo López-Doménech, Josef T. Kittler
Cell Rep. 2019 Feb 19; 26(8): 2037–2051.e6. Published online 2019 Feb 19. doi: 10.1016/j.celrep.2019.01.092
PMCID:
PMC6381785
AbstractArticle
19.
Behavioral training rescues motor deficits in Cyfip1 haploinsufficiency mouse model of autism spectrum disorders
Sven O. Bachmann, Monika Sledziowska, Ellen Cross, Shireene Kalbassi, Sophie Waldron, Fangli Chen, Adam Ranson, Stéphane J. Baudouin
Transl Psychiatry. 2019; 9: 29. Published online 2019 Jan 21. doi: 10.1038/s41398-018-0338-9
PMCID:
PMC6341103
AbstractArticlePDF–1.8M
20.
Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice
Yinhua Zhang, Hyojin Kang, Yeunkum Lee, Yoonhee Kim, Bokyoung Lee, Jin Yong Kim, Chunmei Jin, Shinhyun Kim, Hyun Kim, Kihoon Han
Front Mol Neurosci. 2018; 11: 482. Published online 2019 Jan 4. doi: 10.3389/fnmol.2018.00482
PMCID:
PMC6338024
AbstractArticlePDF–2.8M

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