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Select item 111054171.

Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway

Takeshi Oichi, Yuki Taniguchi, Kazuhito Soma, Yasushi Oshima, Fumiko Yano, Yoshifumi Mori, Ryota Chijimatsu, Joo-ri Kim-Kaneyama, Sakae Tanaka, Taku Saito

Cell Mol Life Sci. 2019 Dec; 76(23): 4795–4809. Published online 2019 Jun 14. doi: 10.1007/s00018-019-03188-0

Correction in:: Cell Mol Life Sci. 2019 Dec; 76(23): 4811–4812.

PMCID:: PMC11105417

Abstract Article PDF–6.4M

Select item 109655552.

The Fbn1 gene variant governs passive ascending aortic mechanics in the mgΔ^lpn mouse model of Marfan syndrome when superimposed to perlecan haploinsufficiency

Samar A. Tarraf, Rodrigo Barbosa de Souza, Ashley Herrick, Lygia V. Pereira, Chiara Bellini

Front Cardiovasc Med. 2024; 11: 1319164. Published online 2024 Mar 13. doi: 10.3389/fcvm.2024.1319164

PMCID:: PMC10965555

Abstract Article PDF–32M

Select item 109249613.

In vivo phenotypic vascular dysfunction extends beyond the aorta in a mouse model for fibrillin-1 (Fbn1) mutation

T. Curry, M. E. Barrameda, T. Currier Thomas, M. Esfandiarei

Sci Rep. 2024; 14: 5779. Published online 2024 Mar 9. doi: 10.1038/s41598-024-56438-y

PMCID:: PMC10924961

Abstract Article PDF–2.8M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108614875.

Aqueous humor TGFβ and fibrillin-1 in Tsk mice reveal clues to POAG pathogenesis

James C. Tan, MinHee K. Ko, Jeong-Im Woo, Kenneth L. Lu, Jonathan A. Kelber

Sci Rep. 2024; 14: 3517. Published online 2024 Feb 12. doi: 10.1038/s41598-024-53659-z

PMCID:: PMC10861487

Abstract Article PDF–1.4M

Select item 107098256.

Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung

Autumn McKnite, Hyung-Seok Kim, Joshua Silva, Jan L. Christian

Dev Dyn. Author manuscript; available in PMC 2023 Dec 9.

Published in final edited form as: Dev Dyn. 2023 Jun; 252(6): 761–769. Published online 2023 Mar 6. doi: 10.1002/dvdy.578

PMCID:: PMC10709825

Abstract Article PDF–1.8M

Select item 104874617.

17 β-Estradiol Impedes Aortic Root Dilation and Rupture in Male Marfan Mice

Louis Saddic, Sean Escopete, Lior Zilberberg, Shannon Kalsow, Divya Gupta, Mansoureh Eghbali, Sarah Parker

Int J Mol Sci. 2023 Sep; 24(17): 13571. Published online 2023 Sep 1. doi: 10.3390/ijms241713571

PMCID:: PMC10487461

Abstract Article PDF–6.0M

Select item 104348268.

Klf4 is not required for smooth muscle cell phenotype modulation in Marfan syndrome aortic aneurysm

Albert J. Pedroza, Alex R. Dalal, Rohan Shad, Nobu Yokoyama, Ken Nakamura, Olivia Mitchel, Casey Gilles, William Hiesinger, Michael P. Fischbein

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2023 Jun; 43(6): 971–978. Published online 2023 Apr 27. doi: 10.1161/ATVBAHA.122.318509

PMCID:: PMC10434826

Abstract Article PDF–1.3M

Select item 103791839.

Hyperuricaemia Does Not Interfere with Aortopathy in a Murine Model of Marfan Syndrome

Isaac Rodríguez-Rovira, Angela López-Sainz, Maria Encarnación Palomo-Buitrago, Belen Pérez, Francesc Jiménez-Altayó, Victoria Campuzano, Gustavo Egea

Int J Mol Sci. 2023 Jul; 24(14): 11293. Published online 2023 Jul 10. doi: 10.3390/ijms241411293

PMCID:: PMC10379183

Abstract Article PDF–2.3M

Select item 1026597310.

Fibrillin-1 regulates endothelial sprouting during angiogenesis

Florian Alonso, Yuechao Dong, Ling Li, Tiya Jahjah, Jean-William Dupuy, Isabelle Fremaux, Dieter P. Reinhardt, Elisabeth Génot

Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2221742120. Published online 2023 May 30. doi: 10.1073/pnas.2221742120

PMCID:: PMC10265973

Abstract Article PDF–15M

Select item 1022877211.

Retinal transcriptome of neonatal mice after optic nerve injury

Shi-Qi Yao, Meng Wang, Jia-Jian Liang, Tsz Kin Ng, Ling-Ping Cen

PLoS One. 2023; 18(5): e0286344. Published online 2023 May 30. doi: 10.1371/journal.pone.0286344

PMCID:: PMC10228772

Abstract Article PDF–2.8M

Select item 1012513012.

IL11 (Interleukin-11) Causes Emphysematous Lung Disease in a Mouse Model of Marfan Syndrome

Benjamin Ng, Chen Xie, Liping Su, Fathima F. Kuthubudeen, Xiu-Yi Kwek, Daryl Yeong, Chee Jian Pua, Stuart A. Cook, Wei-Wen Lim

Arterioscler Thromb Vasc Biol. 2023 May; 43(5): 739–754. Published online 2023 Apr 27. doi: 10.1161/ATVBAHA.122.318802

PMCID:: PMC10125130

Abstract Article PDF–6.9M

Select item 1011931513.

AGGF1 therapy inhibits thoracic aortic aneurysms by enhancing integrin α7-mediated inhibition of TGF-β1 maturation and ERK1/2 signaling

Xingwen Da, Ziyan Li, Xiaofan Huang, Zuhan He, Yubing Yu, Tongtong Tian, Chengqi Xu, Yufeng Yao, Qing K. Wang

Nat Commun. 2023; 14: 2265. Published online 2023 Apr 20. doi: 10.1038/s41467-023-37809-x

PMCID:: PMC10119315

Abstract Article PDF–11M

Select item 1010870614.

A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development

Rhian Stavely, Ryo Hotta, Richard A. Guyer, Nicole Picard, Ahmed A. Rahman, Meredith Omer, Adam Soos, Emoke Szocs, Jessica Mueller, Allan M. Goldstein, Nandor Nagy

Development. 2023 Mar 1; 150(5): dev201090. Published online 2023 Mar 6. doi: 10.1242/dev.201090

PMCID:: PMC10108706

Abstract Article

Select item 994635215.

Asprosin promotes feeding through SK channel–dependent activation of AgRP neurons

Bing Feng, Hesong Liu, Ila Mishra, Clemens Duerrschmid, Peiyu Gao, Pingwen Xu, Chunmei Wang, Yanlin He

Sci Adv. 2023 Feb; 9(8): eabq6718. Published online 2023 Feb 22. doi: 10.1126/sciadv.abq6718

PMCID:: PMC9946352

Abstract Article PDF–1.8M

Select item 979755616.

Endothelial dysfunction in Marfan syndrome mice is restored by resveratrol

Arnout Mieremet, Miesje van der Stoel, Siyu Li, Evrim Coskun, Tsveta van Krimpen, Stephan Huveneers, Vivian de Waard

Sci Rep. 2022; 12: 22504. Published online 2022 Dec 28. doi: 10.1038/s41598-022-26662-5

PMCID:: PMC9797556

Abstract Article PDF–12M

Select item 962426217.

Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction

Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld

Circ Res. Author manuscript; available in PMC 2023 Aug 19.

Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955

PMCID:: PMC9624262

Abstract Article PDF–4.5M

Select item 960672218.

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development

Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener

Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002

PMCID:: PMC9606722

Abstract Article PDF–6.7M

Select item 960637519.

Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs

Wenxia Wang, Swarna Bale, Jun Wei, Bharath Yalavarthi, Dibyendu Bhattacharyya, Jing Jing Yan, Hiam Abdala-Valencia, Dan Xu, Hanshi Sun, Roberta G. Marangoni, Erica Herzog, Sergejs Berdnikovs, Stephen D. Miller, Amr H. Sawalha, Pei-Suen Tsou, Kentaro Awaji, Takashi Yamashita, Shinichi Sato, Yoshihide Asano, Chinnaswamy Tiruppathi, Anjana Yeldandi, Bettina C. Schock, Swati Bhattacharyya, John Varga

Nat Commun. 2022; 13: 6358. Published online 2022 Oct 26. doi: 10.1038/s41467-022-33767-y

Correction in:: Nat Commun. 2023; 14: 523.

PMCID:: PMC9606375

Abstract Article PDF–8.8M

Select item 959951520.

Fibrillin-1 Regulates Arteriole Integrity in the Retina

Florian Alonso, Ling Li, Isabelle Fremaux, Dieter Peter Reinhardt, Elisabeth Génot

Biomolecules. 2022 Oct; 12(10): 1330. Published online 2022 Sep 20. doi: 10.3390/biom12101330

PMCID:: PMC9599515

Abstract Article PDF–9.5M

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