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Select item 114660641.

γ1 GABA_A Receptors in Spinal Nociceptive Circuits

Elena Neumann, Teresa Cramer, Mario A. Acuña, Louis Scheurer, Camilla Beccarini, Bernhard Luscher, Hendrik Wildner, Hanns Ulrich Zeilhofer

J Neurosci. 2024 Oct 9; 44(41): e0591242024. Prepublished online 2024 Aug 13. doi: 10.1523/JNEUROSCI.0591-24.2024

PMCID:: PMC11466064

Abstract Article PDF–2.3M

Select item 111841472.

Region and layer-specific expression of GABA_A receptor isoforms and KCC2 in developing cortex

Kirill Zavalin, Anjana Hassan, Yueli Zhang, Zain Khera, Andre H. Lagrange

Front Cell Neurosci. 2024; 18: 1390742. Published online 2024 Jun 4. doi: 10.3389/fncel.2024.1390742

PMCID:: PMC11184147

Abstract Article PDF–17M

Select item 110833483.

Modulating Endoplasmic Reticulum Chaperones and Mutant Protein Degradation in GABRG2(Q390X) Associated with Genetic Epilepsy with Febrile Seizures Plus and Dravet Syndrome

Sarah Poliquin, Gerald Nwosu, Karishma Randhave, Wangzhen Shen, Carson Flamm, Jing-Qiong Kang

Int J Mol Sci. 2024 May; 25(9): 4601. Published online 2024 Apr 23. doi: 10.3390/ijms25094601

PMCID:: PMC11083348

Abstract Article PDF–7.0M

Select item 110705594.

Microglial TNFα controls daily changes in synaptic GABA_ARs and sleep slow waves

Maria Joana Pinto, Lucy Bizien, Julie M.J. Fabre, Nina Ðukanović, Valentin Lepetz, Fiona Henderson, Marine Pujol, Romain W. Sala, Thibault Tarpin, Daniela Popa, Antoine Triller, Clément Léna, Véronique Fabre, Alain Bessis

J Cell Biol. 2024 Jul 1; 223(7): e202401041. Published online 2024 May 2. doi: 10.1083/jcb.202401041

PMCID:: PMC11070559

Abstract Article PDF–5.1M

Select item 109981955.

Increased GABA signaling in liver macrophage promotes HBV replication in HBV-carrier mice

Yunling Chen, Zhaoqing Yin, Xiaonan Zhang, Yiwei Zhao, Tinghao Liu, Wei-Yang Lu, Shuanglian Wang

Virus Res. 2024 Jun; 344: 199366. Published online 2024 Mar 30. doi: 10.1016/j.virusres.2024.199366

PMCID:: PMC10998195

Abstract Article PDF–373K

Select item 109176606.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693507.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 105918988.

Epilepsy plus Blindness in Microdeletion of GABRA1 and GABRG2 in Mouse and Human

Qi Zhang, Cynthia Forster-Gibson, Eduard Bercovici, Alexandra Bernardo, Fei Ding, Wangzhen Shen, Katherine Langer, Tonia Rex, Jing-Qiong Kang

Exp Neurol. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Exp Neurol. 2023 Nov; 369: 114537. Published online 2023 Sep 11. doi: 10.1016/j.expneurol.2023.114537

PMCID:: PMC10591898

Abstract Article PDF–975K

Select item 103078529.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 1027213910.

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice

Hyoseon Oh, Suho Lee, Yusang Oh, Seongbin Kim, Young Seo Kim, Yeji Yang, Woochul Choi, Ye-Eun Yoo, Heejin Cho, Seungjoon Lee, Esther Yang, Wuhyun Koh, Woojin Won, Ryunhee Kim, C. Justin Lee, Hyun Kim, Hyojin Kang, Jin Young Kim, Taeyun Ku, Se-Bum Paik, Eunjoon Kim

Nat Commun. 2023; 14: 3547. Published online 2023 Jun 15. doi: 10.1038/s41467-023-39203-z

PMCID:: PMC10272139

Abstract Article PDF–4.3M

Select item 1020895811.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 995051512.

Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age

Jorge Lopez-Tello, Amanda N. Sferruzzi-Perri

Front Endocrinol (Lausanne) 2023; 14: 1116770. Published online 2023 Feb 10. doi: 10.3389/fendo.2023.1116770

PMCID:: PMC9950515

Abstract Article PDF–4.2M

Select item 993821613.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 930101114.

The Maternal Microbiome Programs the m⁶A Epitranscriptome of the Mouse Fetal Brain and Intestine

Zhuoyu Xiao, Sun Liu, Zengguang Li, Jinru Cui, Hailan Wang, Zihan Wang, Qihuan Ren, Laixin Xia, Zhijian Wang, Yuan Li

Front Cell Dev Biol. 2022; 10: 882994. Published online 2022 Jul 7. doi: 10.3389/fcell.2022.882994

PMCID:: PMC9301011

Abstract Article PDF–2.5M

Select item 901607815.

An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABA_A receptor

Gerasimos Anagnostopoulos, Omar Motiño, Sijing Li, Vincent Carbonnier, Hui Chen, Valentina Sica, Sylvère Durand, Mélanie Bourgin, Fanny Aprahamian, Nitharsshini Nirmalathasan, Romain Donne, Chantal Desdouets, Marcelo Simon Sola, Konstantina Kotta, Léa Montégut, Flavia Lambertucci, Didier Surdez, Grossetête Sandrine, Olivier Delattre, Maria Chiara Maiuri, José Manuel Bravo-San Pedro, Isabelle Martins, Guido Kroemer

Cell Death Dis. 2022 Apr; 13(4): 356. Published online 2022 Apr 18. doi: 10.1038/s41419-022-04834-5