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Select item 113994071.

Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion

Soraia Barão, Yijun Xu, José P. Llongueras, Rachel Vistein, Loyal Goff, Kristina J. Nielsen, Byoung-Il Bae, Richard S. Smith, Christopher A. Walsh, Genevieve Stein-O’Brien, Ulrich Müller

Nat Commun. 2024; 15: 8043. Published online 2024 Sep 14. doi: 10.1038/s41467-024-52443-x

PMCID:: PMC11399407

Abstract Article PDF–12M

Select item 112879312.

HES1 is required for mouse fetal hematopoiesis

Anthony Z. Zhu, Zhilin Ma, Emily V. Wolff, Zichen Lin, Zhenxia J. Gao, Xue Li, Wei Du

Stem Cell Res Ther. 2024; 15: 235. Published online 2024 Jul 29. doi: 10.1186/s13287-024-03836-8

PMCID:: PMC11287931

Abstract Article PDF–3.7M

Select item 112161733.

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development

James F. Clark, Philippe Soriano

Genes Dev. 2024 May 1; 38(9-10): 393–414. doi: 10.1101/gad.351593.124

PMCID:: PMC11216173

Abstract Article PDF–17M

Select item 111617324.

RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells

Nour Sfeir, Marilyn Kajdan, Stéphan Jalaguier, Sandrine Bonnet, Catherine Teyssier, Samuel Pyrdziak, Rong Yuan, Emilie Bousquet, Antonio Maraver, Florence Bernex, Nelly Pirot, Florence Boissière‐Michot, Audrey Castet‐Nicolas, Marion Lapierre, Vincent Cavaillès

Mol Oncol. 2024 Jun; 18(6): 1510–1530. Published online 2024 Mar 8. doi: 10.1002/1878-0261.13626

PMCID:: PMC11161732

Abstract Article PDF–6.3M

Select item 111149975.

Hes-1 regulates the excitatory fate of neural progenitors through modulation of Tlx3 (HOX11L2) expression

Chandrasekharan Lalitha Indulekha, Thulasi Sheela Divya, Mundackal Sivaraman Divya, Rajendran Sanalkumar, Vazhanthodi Abdul Rasheed, Sivadasan Bindu Dhanesh, Anu Sebin, Amitha George, Jackson James

Cell Mol Life Sci. 2012 Feb; 69(4): 611–627. Published online 2011 Jul 9. doi: 10.1007/s00018-011-0765-8

PMCID:: PMC11114997

Abstract Article PDF–1.0M

Select item 109385886.

Integrated single-cell transcriptomic and epigenetic study of cell state transition and lineage commitment in embryonic mouse cerebellum

Nagham Khouri-Farah, Qiuxia Guo, Kerry Morgan, Jihye Shin, James Y. H. Li

Sci Adv. 2022 Apr; 8(13): eabl9156. Published online 2022 Apr 1. doi: 10.1126/sciadv.abl9156

PMCID:: PMC10938588

Abstract Article PDF–16M

Select item 108376287.

NOTCH2 promotes osteoclast maturation and metabolism and modulates the transcriptome profile during osteoclastogenesis

Ernesto Canalis, Lauren Schilling, Jungeun Yu, Emily Denker

J Biol Chem. 2024 Feb; 300(2): 105613. Published online 2023 Dec 28. doi: 10.1016/j.jbc.2023.105613

PMCID:: PMC10837628

Abstract Article PDF–6.6M

Select item 105772788.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 105436439.

Mettl14-mediated m⁶A modification ensures the cell-cycle progression of late-born retinal progenitor cells

Liang Li, Yue Sun, Alexander E. Davis, Sahil H. Shah, Lobna K. Hamed, Man-Ru Wu, Cheng-Hui Lin, Jun B. Ding, Sui Wang

Cell Rep. Author manuscript; available in PMC 2023 Oct 2.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112596. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112596

PMCID:: PMC10543643

Abstract Article PDF–3.9M

Select item 1052202110.

Notch pathway mutants do not equivalently perturb mouse embryonic retinal development

Bernadett Bosze, Julissa Suarez-Navarro, Illiana Cajias, Joseph A. Brzezinski IV, Nadean L. Brown

PLoS Genet. 2023 Sep; 19(9): e1010928. Published online 2023 Sep 26. doi: 10.1371/journal.pgen.1010928

PMCID:: PMC10522021

Abstract Article PDF–5.9M

Select item 1035903511.

Lrrn1 Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti

Helen R. Maunsell, Kathryn Ellis, Matthew W. Kelley, Elizabeth Carroll Driver

J Neurosci. 2023 Jul 19; 43(29): 5305–5318. doi: 10.1523/JNEUROSCI.2141-22.2023

PMCID:: PMC10359035

Abstract Article PDF–7.2M

Select item 1026752012.

Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development

Yuki Matsushita, Hiroaki Manabe, Takahiro Ohyama, Shogo Nakamura, Mizuki Nagata, Wanida Ono, Noriaki Ono

J Biol Chem. 2023 Jun; 299(6): 104805. Published online 2023 May 11. doi: 10.1016/j.jbc.2023.104805

PMCID:: PMC10267520

Abstract Article PDF–7.3M

Select item 1004594813.

HES1-mediated down-regulation of miR-138 sustains NOTCH1 activation and promotes proliferation and invasion in renal cell carcinoma

Shuangjie Liu, Lei Dou, Miao Miao, Xiaojun Man, Baojun Wei, Zhaowei Jiang, Yongze Ouyang, Toshinori Ozaki, Meng Yu, Yuyan Zhu

J Exp Clin Cancer Res. 2023; 42: 72. Published online 2023 Mar 28. doi: 10.1186/s13046-023-02625-0

PMCID:: PMC10045948

Abstract Article PDF–11M

Select item 1000087614.

Notch Signaling Pathway in Tooth Shape Variations throughout Evolution

Thimios A. Mitsiadis, Pierfrancesco Pagella, Helder Gomes Rodrigues, Alexander Tsouknidas, Liza L. Ramenzoni, Freddy Radtke, Albert Mehl, Laurent Viriot

Cells. 2023 Mar; 12(5): 761. Published online 2023 Feb 27. doi: 10.3390/cells12050761

PMCID:: PMC10000876

Abstract Article PDF–5.9M

Select item 998443415.

General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions

Susanna Säisä-Borreill, Guillaume Davidson, Thomas Kleiber, Andréa Thevenot, Elisabeth Martin, Stanislas Mondot, Hervé Blottière, Alexandra Helleux, Gabrielle Mengus, Michelina Plateroti, Isabelle Duluc, Irwin Davidson, Jean-Noel Freund

Cell Death Differ. 2023 Mar; 30(3): 839–853. Published online 2023 Jan 13. doi: 10.1038/s41418-022-01109-6

PMCID:: PMC9984434

Abstract Article PDF–8.1M

Select item 986777416.

Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development

Xiaochan Xu, Philip Allan Seymour, Kim Sneppen, Ala Trusina, Anuska la Rosa Egeskov-Madsen, Mette Christine Jørgensen, Mogens Høgh Jensen, Palle Serup

Nat Commun. 2023; 14: 348. Published online 2023 Jan 21. doi: 10.1038/s41467-023-35963-w

PMCID:: PMC9867774

Abstract Article PDF–4.4M

Select item 985174617.

Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man

Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper

Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192

PMCID:: PMC9851746

Abstract Article PDF–3.5M

Select item 979067518.

PRDM16 expression and function in mammalian cochlear development

Michael Ebeid, Kathy Barnas, Hongji Zhang, Amal Yaghmour, Gabriele Noreikaite, Bryan C. Bjork

Dev Dyn. 2022 Oct; 251(10): 1666–1683. Published online 2022 May 7. doi: 10.1002/dvdy.480

PMCID:: PMC9790675

Abstract Article PDF–17M

Select item 971867219.

Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABA_B1 receptor expression

Tong Ni, Li Zhu, Shuai Wang, Weili Zhu, Yanxue Xue, Yingjie Zhu, Dongliang Ma, Hongyan Wang, Fanglin Guan, Teng Chen

Mol Psychiatry. 2022; 27(10): 4009–4022. Published online 2022 Jun 22. doi: 10.1038/s41380-022-01662-z

PMCID:: PMC9718672

Abstract Article PDF–5.3M

Select item 971853220.

Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis

Xiaodong Li, Patrick J Gordon, John A Gaynes, Alexandra W Fuller, Randy Ringuette, Clayton P Santiago, Valerie Wallace, Seth Blackshaw, Pulin Li, Edward M Levine

eLife. 2022; 11: e78342. Published online 2022 Dec 2. doi: 10.7554/eLife.78342