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Select item 109179001.

β3-Adrenoceptor as a new player in the sympathetic regulation of the renal acid–base homeostasis

Serena Milano, Ilenia Saponara, Andrea Gerbino, Dominga Lapi, Ludovica Lela, Monica Carmosino, Massimo Dal Monte, Paola Bagnoli, Maria Svelto, Giuseppe Procino

Front Physiol. 2024; 15: 1304375. Published online 2024 Feb 22. doi: 10.3389/fphys.2024.1304375

PMCID:: PMC10917900

Abstract Article PDF–2.4M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104472373.

Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms

Elodie Grockowiak, Claudia Korn, Justyna Rak, Veronika Lysenko, Adrien Hallou, Francesca M. Panvini, Matthew Williams, Claire Fielding, Zijian Fang, Eman Khatib-Massalha, Andrés García-García, Juan Li, Reema A. Khorshed, Sara González-Antón, E. Joanna Baxter, Anjali Kusumbe, Bridget S. Wilkins, Anna Green, Benjamin D. Simons, Claire N. Harrison, Anthony R. Green, Cristina Lo Celso, Alexandre P. A. Theocharides, Simón Méndez-Ferrer

Nat Cancer. 2023; 4(8): 1193–1209. Published online 2023 Aug 7. doi: 10.1038/s43018-023-00607-x

PMCID:: PMC10447237

Abstract Article PDF–18M

Select item 103420674.

Multisensory Stimulation Reverses Memory Impairment in Adrβ₃KO Male Mice

Thaís T. Ravache, Alice Batistuzzo, Gabriela G. Nunes, Thiago G. B. Gomez, Fernanda B. Lorena, Bruna P. P. Do Nascimento, Maria Martha Bernardi, Eduarda R. R. Lima, Daniel O. Martins, Ana Carolina P. Campos, Rosana L. Pagano, Miriam O. Ribeiro

Int J Mol Sci. 2023 Jul; 24(13): 10522. Published online 2023 Jun 23. doi: 10.3390/ijms241310522

PMCID:: PMC10342067

Abstract Article PDF–2.3M

Select item 103227165.

GDF15 promotes weight loss by enhancing energy expenditure in muscle

Dongdong Wang, Logan K. Townsend, Geneviève J. DesOrmeaux, Sara M. Frangos, Battsetseg Batchuluun, Lauralyne Dumont, Rune Ehrenreich Kuhre, Elham Ahmadi, Sumei Hu, Irena A. Rebalka, Jaya Gautam, Maria Joy Therese Jabile, Chantal A. Pileggi, Sonia Rehal, Eric M. Desjardins, Evangelia E. Tsakiridis, James S. V. Lally, Emma Sara Juracic, A. Russell Tupling, Hertzel C. Gerstein, Guillaume Paré, Theodoros Tsakiridis, Mary-Ellen Harper, Thomas J. Hawke, John R. Speakman, Denis P. Blondin, Graham P. Holloway, Sebastian Beck Jørgensen, Gregory R. Steinberg

Nature. 2023; 619(7968): 143–150. Published online 2023 Jun 28. doi: 10.1038/s41586-023-06249-4

PMCID:: PMC10322716

Abstract Article PDF–26M

Select item 102817936.

β3AR-Dependent BDNF Generation Limits Chronic Post-Ischemic Heart Failure

Alessandro Cannavo, Seungho Jun, Giuseppe Rengo, Federica Marzano, Jacopo Agrimi, Daniela Liccardo, Andrea Elia, Gizem Keceli, Giovanna G. Altobelli, Lorenzo Marcucci, Aram Megighian, Erhe Gao, Ning Feng, Kai Kammers, Nicola Ferrara, Livio Finos, Walter J. Koch, Nazareno Paolocci

Circ Res. Author manuscript; available in PMC 2024 Mar 31.

Published in final edited form as: Circ Res. 2023 Mar 31; 132(7): 867–881. Published online 2023 Mar 8. doi: 10.1161/CIRCRESAHA.122.321583

PMCID:: PMC10281793

Abstract Article PDF–2.8M

Select item 97988857.

Brain motor and fear circuits regulate leukocytes during acute stress

Wolfram C. Poller, Jeffrey Downey, Agnes A. Mooslechner, Nargis Khan, Long Li, Christopher T. Chan, Cameron S. McAlpine, Chunliang Xu, Florian Kahles, Shun He, Henrike Janssen, John E. Mindur, Sumnima Singh, Máté G. Kiss, Laura Alonso-Herranz, Yoshiko Iwamoto, Rainer H. Kohler, Lai Ping Wong, Kashish Chetal, Scott J. Russo, Ruslan I. Sadreyev, Ralph Weissleder, Matthias Nahrendorf, Paul S. Frenette, Maziar Divangahi, Filip K. Swirski

Nature. Author manuscript; available in PMC 2022 Dec 29.

Published in final edited form as: Nature. 2022 Jul; 607(7919): 578–584. Published online 2022 May 30. doi: 10.1038/s41586-022-04890-z

PMCID:: PMC9798885

Abstract Article PDF–4.5M

Select item 97423158.

The rheumatoid arthritis drug auranofin lowers leptin levels and exerts anti-diabetic effects in obese mice

Aaron R. Cox, Peter M. Masschelin, Pradip K. Saha, Jessica B. Felix, Robert Sharp, Zeqin Lian, Yan Xia, Natasha Chernis, David A. Bader, Kang Ho Kim, Xin Li, Jun Yoshino, Xin Li, Gang Li, Zheng Sun, Huaizhu Wu, Cristian Coarfa, David D. Moore, Samuel Klein, Kai Sun, Sean M. Hartig

Cell Metab. Author manuscript; available in PMC 2023 Dec 6.

Published in final edited form as: Cell Metab. 2022 Dec 6; 34(12): 1932–1946.e7. Published online 2022 Oct 14. doi: 10.1016/j.cmet.2022.09.019

PMCID:: PMC9742315

Abstract Article PDF–3.3M

Select item 93085059.

A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange

Kuan Zhang, Erica Yao, Shao-An Wang, Ethan Chuang, Julia Wong, Liliana Minichiello, Andrew Schroeder, Walter Eckalbar, Paul J. Wolters, Pao-Tien Chuang

Dev Cell. Author manuscript; available in PMC 2023 Jul 11.

Published in final edited form as: Dev Cell. 2022 Jul 11; 57(13): 1566–1581.e7. Published online 2022 Jun 16. doi: 10.1016/j.devcel.2022.05.021

PMCID:: PMC9308505

Abstract Article PDF–5.9M

Select item 924570710.

Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression

Seongjun Byun, Chan Hyeong Lee, Hyeongmin Jeong, Hyejin Kim, Hyug Moo Kwon, Sungho Park, Kyungjae Myung, Jungeun An, Myunggon Ko

Proc Natl Acad Sci U S A. 2022 Jun 28; 119(26): e2205626119. Published online 2022 Jun 23. doi: 10.1073/pnas.2205626119

PMCID:: PMC9245707

Abstract Article PDF–3.2M

Select item 920741311.

The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis

Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang

Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624

PMCID:: PMC9207413

Abstract Article PDF–6.0M

Select item 920252312.

Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism

Esther Paulo, Yun Zhang, Ruchi Masand, Tony L. Huynh, Youngho Seo, Danielle L. Swaney, Margaret Soucheray, Erica Stevenson, David Jimenez-Morales, Nevan J. Krogan, Biao Wang

Cell Rep. Author manuscript; available in PMC 2022 Jun 16.

Published in final edited form as: Cell Rep. 2021 Sep 21; 36(12): 109742. doi: 10.1016/j.celrep.2021.109742

PMCID:: PMC9202523

Abstract Article PDF–4.2M

Select item 902946513.

HIF-1-Dependent Induction of β3 Adrenoceptor: Evidence from the Mouse Retina

Rosario Amato, Francesco Pisani, Emiliano Laudadio, Maurizio Cammalleri, Martina Lucchesi, Silvia Marracci, Luca Filippi, Roberta Galeazzi, Maria Svelto, Massimo Dal Monte, Paola Bagnoli

Cells. 2022 Apr; 11(8): 1271. Published online 2022 Apr 8. doi: 10.3390/cells11081271

PMCID:: PMC9029465

Abstract Article PDF–2.5M

Select item 883155914.

ADRB3 induces mobilization and inhibits differentiation of both breast cancer cells and myeloid-derived suppressor cells

Zhiling Zhou, Jiaxin Zhan, Qiong Luo, Xinghua Hou, Shuxia Wang, Dingzhang Xiao, Zhi Xie, Haidan Liang, Shuguang Lin, Meng Zheng

Cell Death Dis. 2022 Feb; 13(2): 141. Published online 2022 Feb 10. doi: 10.1038/s41419-022-04603-4

PMCID:: PMC8831559

Abstract Article PDF–4.4M

Select item 879538415.

Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis

Claire Fielding, Andrés García-García, Claudia Korn, Stephen Gadomski, Zijian Fang, Juan L. Reguera, José A. Pérez-Simón, Berthold Göttgens, Simón Méndez-Ferrer

Nat Commun. 2022; 13: 543. Published online 2022 Jan 27. doi: 10.1038/s41467-022-28175-1

PMCID:: PMC8795384

Abstract Article PDF–2.6M

Select item 875978116.

β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity

Joseph M. Valentine, Maryam Ahmadian, Omer Keinan, Mohammad Abu-Odeh, Peng Zhao, Xin Zhou, Mark P. Keller, Hui Gao, Ruth T. Yu, Christopher Liddle, Michael Downes, Jin Zhang, Aldons J. Lusis, Alan D. Attie, Ronald M. Evans, Mikael Rydén, Alan R. Saltiel

J Clin Invest. 2022 Jan 18; 132(2): e153357. Published online 2022 Jan 18. doi: 10.1172/JCI153357

PMCID:: PMC8759781

Abstract Article PDF–9.7M

Select item 841489917.

Activation of the Thiazide-Sensitive Sodium-Chloride Cotransporter by Beta3-Adrenoreceptor in the Distal Convoluted Tubule

Serena Milano, Monica Carmosino, Andrea Gerbino, Ilenia Saponara, Dominga Lapi, Massimo Dal Monte, Paola Bagnoli, Maria Svelto, Giuseppe Procino

Front Physiol. 2021; 12: 695824. Published online 2021 Aug 13. doi: 10.3389/fphys.2021.695824

PMCID:: PMC8414899

Abstract Article PDF–21M

Select item 838943818.

Impact of thermogenesis induced by chronic β3-adrenergic receptor agonist treatment on inflammatory and infectious response during bacteremia in mice

Patrick Munro, Samah Rekima, Agnès Loubat, Christophe Duranton, Didier F. Pisani, Laurent Boyer

PLoS One. 2021; 16(8): e0256768. Published online 2021 Aug 26. doi: 10.1371/journal.pone.0256768

PMCID:: PMC8389438

Abstract Article PDF–3.8M

Select item 806653519.

D-Mannitol Induces a Brown Fat-like Phenotype via a β3-Adrenergic Receptor-Dependent Mechanism

Hui-Jeon Jeon, Dong Kyu Choi, JaeHeon Choi, Seul Lee, Heejin Lee, Ji Hoon Yu, Sang-Hyun Min

Cells. 2021 Apr; 10(4): 768. Published online 2021 Mar 31. doi: 10.3390/cells10040768

PMCID:: PMC8066535

Abstract Article PDF–18M

Select item 785610420.

Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility

Ying Wang, Qian Shi, Minghui Li, Meimi Zhao, Raghavender Reddy Gopireddy, Jian-Peng Teoh, Bing Xu, Chaoqun Zhu, Kyle E. Ireton, Sanghavi Srinivasan, Shaoliang Chen, Paul J. Gasser, Julie Bossuyt, Johannes W. Hell, Donald M. Bers, Yang K. Xiang

Circ Res. Author manuscript; available in PMC 2022 Jan 22.

Published in final edited form as: Circ Res. 2021 Jan 22; 128(2): 246–261. Published online 2020 Nov 13. doi: 10.1161/CIRCRESAHA.120.317452

PMCID:: PMC7856104

Abstract Article PDF–2.6M

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