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Items: 1 to 20 of 43

1.
TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition
Pascual Torres, Santiago Rico-Rios, Miriam Ceron-Codorniu, Marta Santacreu-Vilaseca, David Seoane-Miraz, Yahya Jad, Victòria Ayala, Guillermo Mariño, Maria Beltran, Maria P. Miralles, Pol Andrés-Benito, Joaquin Fernandez-Irigoyen, Enrique Santamaria, Carlos López-Otín, Rosa M. Soler, Monica Povedano, Isidro Ferrer, Reinald Pamplona, Matthew J. A. Wood, Miguel A. Varela, Manuel Portero-Otin
Acta Neuropathol. 2024; 148(1): 45. Published online 2024 Sep 21. doi: 10.1007/s00401-024-02780-4
PMCID:
PMC11416411
AbstractArticlePDF–5.1M
2.
Circ-0000953 deficiency exacerbates podocyte injury and autophagy disorder by targeting Mir665-3p-Atg4b in diabetic nephropathy
Xueqi Liu, Ling Jiang, Hanxu Zeng, Li Gao, Shanshan Guo, Chaoyi Chen, Xinran Liu, Mengya Zhang, Lijuan Ma, Yuanyuan Li, Xiangming Qi, Yonggui Wu
Autophagy. 2024; 20(5): 1072–1097. Published online 2023 Dec 5. doi: 10.1080/15548627.2023.2286128
PMCID:
PMC11135827
AbstractArticlePDF–20M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
ATG4B antagonizes antiviral immunity by GABARAP-directed autophagic degradation of TBK1
Weihong Xie, Chenqiu Zhang, Zheyu Wang, Hui Chen, Tonghui Gu, Tao Zhou, Yaoxing Wu, Fan Xia, Min Li, Jun Wang, Renjie Jiao, Jun Cui, Shouheng Jin
Autophagy. 2023; 19(11): 2853–2868. Published online 2023 Jul 11. doi: 10.1080/15548627.2023.2233846
PMCID:
PMC10549193
AbstractArticlePDF–3.0M
5.
Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components
Gabriel Muciño-Hernández, Pilar Sarah Acevo-Rodríguez, Sandra Cabrera-Benitez, Adán Oswaldo Guerrero, Horacio Merchant-Larios, Susana Castro-Obregón
J Cell Sci. 2023 Jan 1; 136(1): jcs260563. Published online 2023 Jan 12. doi: 10.1242/jcs.260563
PMCID:
PMC10112964
AbstractArticle
6.
Involvement of acetylation of ATG4B in controlling autophagy induction
Haojun Xiong, Liangbo Sun, Jiqin Lian, Fengtian He
Autophagy. 2023; 19(3): 1039–1041. Published online 2022 Sep 2. doi: 10.1080/15548627.2022.2117887
PMCID:
PMC9980631
AbstractArticlePDF–584K
7.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
An intestinal organoid–based platform that recreates susceptibility to T-cell–mediated tissue injury
Yu Matsuzawa-Ishimoto, Ashley Hine, Yusuke Shono, Eugene Rudensky, Amina Lazrak, Frank Yeung, Jessica A. Neil, Xiaomin Yao, Ying-Han Chen, Thomas Heaney, Samantha L. Schuster, Erin E. Zwack, Jordan E. Axelrad, David Hudesman, Jennifer J. Tsai, Katherine Nichols, M. Zahidunnabi Dewan, Michael Cammer, Allison Beal, Sandra Hoffman, Brad Geddes, John Bertin, Chen Liu, Victor J. Torres, P’ng Loke, Marcel R. M. van den Brink, Ken Cadwell
Blood. 2020 Jun 25; 135(26): 2388–2401. Prepublished online 2020 Mar 30. doi: 10.1182/blood.2019004116
PMCID:
PMC7317146
AbstractArticle
10.
A unique transgenic mouse model exhibiting a myeloproliferative disease-like phenotype
Yusuke Kito, Yuki Hanamatsu, Keisuke Kawashima, Chiemi Saigo, Tamotsu Takeuchi
Biol Open. 2019 Nov 15; 8(11): bio044438. Published online 2019 Nov 18. doi: 10.1242/bio.044438
PMCID:
PMC6899036
AbstractArticlePDF–7.2M
11.
Autophagy proteins suppress protective type I interferon signaling in response to the murine gut microbiota
Patricia K. Martin, Amanda Marchiando, Ruliang Xu, Eugene Rudensky, Frank Yeung, Samantha L. Schuster, Elisabeth Kernbauer, Ken Cadwell
Nat Microbiol. Author manuscript; available in PMC 2019 Mar 10.
Published in final edited form as: Nat Microbiol. 2018 Oct; 3(10): 1131–1141. Published online 2018 Sep 10. doi: 10.1038/s41564-018-0229-0
PMCID:
PMC6179362
AbstractArticlePDF–1.7M
12.
Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases
Karlina J. Kauffman, Shenliang Yu, Jiaxin Jin, Brian Mugo, Nathan Nguyen, Aidan O'Brien, Shanta Nag, Alf Håkon Lystad, Thomas J. Melia
Autophagy. 2018; 14(6): 992–1010. Published online 2018 Apr 10. doi: 10.1080/15548627.2018.1437341
PMCID:
PMC6103404
AbstractArticlePDF–2.2M
13.
Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion
Zhenlu Li, Guangzhi Wang, Dongcheng Feng, Guo Zu, Yang Li, Xue Shi, Yan Zhao, Huirong Jing, Shili Ning, Weidong Le, Jihong Yao, Xiaofeng Tian
Cell Death Dis. 2018 May; 9(5): 483. Published online 2018 Apr 30. doi: 10.1038/s41419-018-0518-9
PMCID:
PMC5924757
AbstractArticlePDF–3.7M
14.
Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks
Amrita Ramkumar, Divya Murthy, Desingu Ayyappa Raja, Archana Singh, Anusha Krishnan, Sangeeta Khanna, Archana Vats, Lipi Thukral, Pushkar Sharma, Sridhar Sivasubbu, Rajni Rani, Vivek T. Natarajan, Rajesh S. Gokhale
Autophagy. 2017; 13(8): 1331–1347. Published online 2017 Jun 9. doi: 10.1080/15548627.2017.1327509
PMCID:
PMC5584859
AbstractArticlePDF–1.5M
15.
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
Mads Skytte Rasmussen, Stéphane Mouilleron, Birendra Kumar Shrestha, Martina Wirth, Rebecca Lee, Kenneth Bowitz Larsen, Yakubu Abudu Princely, Nicola O'Reilly, Eva Sjøttem, Sharon A. Tooze, Trond Lamark, Terje Johansen
Autophagy. 2017; 13(5): 834–853. Published online 2017 Feb 15. doi: 10.1080/15548627.2017.1287651
PMCID:
PMC5446077
AbstractArticlePDF–1.9M
16.
Unique role for ATG5 in PMN-mediated immunopathology during M. tuberculosis infection
Jacqueline M. Kimmey, Jeremy P. Huynh, Leslie A. Weiss, Sunmin Park, Amal Kambal, Jayanta Debnath, Herbert W. Virgin, Christina L. Stallings
Nature. Author manuscript; available in PMC 2016 Jun 9.
Published in final edited form as: Nature. 2015 Dec 24; 528(7583): 565–569. Published online 2015 Dec 9. doi: 10.1038/nature16451
PMCID:
PMC4842313
AbstractArticlePDF–1.8M
17.
Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis
Qun Lu, Christine C. Yokoyama, Jesse W. Williams, Megan T. Baldridge, Xiaohua Jin, Brittany DesRochers, Traci Bricker, Craig B. Wilen, Juhi Bagaitkar, Ekaterina Loginicheva, Alexey Sergushichev, Darren Kreamalmeyer, Brian C. Keller, Yan Zhao, Amal Kambal, Douglas R. Green, Jennifer Martinez, Mary C. Dinauer, Michael J. Holtzman, Erika C. Crouch, Wandy Beatty, Adrianus C.M. Boon, Hong Zhang, Gwendalyn J. Randolph, Maxim N. Artyomov, Herbert W. Virgin
Cell Host Microbe. Author manuscript; available in PMC 2017 Jan 13.
Published in final edited form as: Cell Host Microbe. 2016 Jan 13; 19(1): 102–113. doi: 10.1016/j.chom.2015.12.011
PMCID:
PMC4714358
AbstractArticlePDF–2.6M
18.
Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation
Sunmin Park, Michael D. Buck, Chandni Desai, Xin Zhang, Ekaterina Loginicheva, Jennifer Martinez, Michael L. Freeman, Tatsuya Saitoh, Shizuo Akira, Jun-Lin Guan, You-Wen He, Marcia A. Blackman, Scott A. Handley, Beth Levine, Douglas R. Green, Tiffany A. Reese, Maxim N. Artyomov, Herbert W. Virgin
Cell Host Microbe. 2016 Jan 13; 19(1): 91–101. Published online 2016 Feb 2. doi: 10.1016/j.chom.2015.12.010
PMCID:
PMC4714357
AbstractArticlePDF–2.4M
19.
ATG4B (Autophagin-1) Phosphorylation Modulates Autophagy
Zhifen Yang, Rachel P. Wilkie-Grantham, Teruki Yanagi, Chih-Wen Shu, Shu-ichi Matsuzawa, John C. Reed
J Biol Chem. 2015 Oct 30; 290(44): 26549–26561. Published online 2015 Sep 16. doi: 10.1074/jbc.M115.658088
PMCID:
PMC4646313
AbstractArticlePDF–1.7M
20.
Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis
Sandra Cabrera, Mariana Maciel, Iliana Herrera, Teresa Nava, Fabián Vergara, Miguel Gaxiola, Carlos López-Otín, Moisés Selman, Annie Pardo
Autophagy. 2015 Apr; 11(4): 670–684. Published online 2015 Apr 23. doi: 10.1080/15548627.2015.1034409
PMCID:
PMC4502665
AbstractArticlePDF–1.9M

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