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Select item 111862081.

Loss of protein tyrosine phosphatase receptor delta PTPRD increases the number of cortical neurons, impairs synaptic function and induces autistic-like behaviors in adult mice

Bastián I. Cortés, Rodrigo C. Meza, Carlos Ancatén-González, Nicolás M. Ardiles, María-Ignacia Aránguiz, Hideaki Tomita, David R. Kaplan, Francisca Cornejo, Alexia Nunez-Parra, Pablo R. Moya, Andrés E. Chávez, Gonzalo I. Cancino

Biol Res. 2024; 57: 40. Published online 2024 Jun 18. doi: 10.1186/s40659-024-00522-0

PMCID:: PMC11186208

Abstract Article PDF–7.5M

Select item 110822732.

Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala

Yoshifumi Matsumoto, Hideki Miwa, Kei-ichi Katayama, Arata Watanabe, Kazuyuki Yamada, Takashi Ito, Shinsuke Nakagawa, Jun Aruga

Front Mol Neurosci. 2024; 17: 1386924. Published online 2024 Apr 26. doi: 10.3389/fnmol.2024.1386924

PMCID:: PMC11082273

Abstract Article PDF–4.8M

Select item 109373473.

Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex

Francisca Cornejo, Nayhara Franchini, Bastián I. Cortés, Daniela Elgueta, Gonzalo I. Cancino

Front Cell Dev Biol. 2024; 12: 1357862. Published online 2024 Feb 29. doi: 10.3389/fcell.2024.1357862

PMCID:: PMC10937347

Abstract Article PDF–3.3M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108839645.

Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons

Kyung Ah Han, Taek-Han Yoon, Jinhu Kim, Jusung Lee, Ju Yeon Lee, Gyubin Jang, Ji Won Um, Jong Kyoung Kim, Jaewon Ko

Nat Commun. 2024; 15: 1624. Published online 2024 Feb 22. doi: 10.1038/s41467-024-45695-0

Correction in:: Nat Commun. 2024; 15: 2068.

Correction in:: Nat Commun. 2024; 15: 6194.

PMCID:: PMC10883964

Abstract Article PDF–6.4M

Select item 104355796.

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit

Alessandra Sclip, Thomas C. Südhof

Nat Commun. 2023; 14: 4976. Published online 2023 Aug 17. doi: 10.1038/s41467-023-40526-0

PMCID:: PMC10435579

Abstract Article PDF–9.2M

Select item 103233647.

PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum

Yuto Okuno, Kazuto Sakoori, Kyoko Matsuyama, Miwako Yamasaki, Masahiko Watanabe, Kouichi Hashimoto, Takaki Watanabe, Masanobu Kano

Front Mol Neurosci. 2023; 16: 1206245. Published online 2023 Jun 22. doi: 10.3389/fnmol.2023.1206245

PMCID:: PMC10323364

Abstract Article PDF–4.6M

Select item 101984998.

Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating

Emily V. Ho, Amanda Welch, Summer L. Thompson, James A. Knowles, Stephanie C. Dulawa

PLoS One. 2023; 18(5): e0277446. Published online 2023 May 19. doi: 10.1371/journal.pone.0277446

PMCID:: PMC10198499

Abstract Article PDF–1.2M

Select item 99463529.

Asprosin promotes feeding through SK channel–dependent activation of AgRP neurons

Bing Feng, Hesong Liu, Ila Mishra, Clemens Duerrschmid, Peiyu Gao, Pingwen Xu, Chunmei Wang, Yanlin He

Sci Adv. 2023 Feb; 9(8): eabq6718. Published online 2023 Feb 22. doi: 10.1126/sciadv.abq6718

PMCID:: PMC9946352

Abstract Article PDF–1.8M

Select item 924826810.

Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development

Ian M. Henderson, Fanxun Zeng, Nazmul H. Bhuiyan, Dan Luo, Maria Martinez, Jane Smoake, Fangchao Bi, Chamani Perera, David Johnson, Thomas E. Prisinzano, Wei Wang, George R. Uhl

Biochem Pharmacol. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Biochem Pharmacol. 2022 Jan; 195: 114868. Published online 2021 Dec 2. doi: 10.1016/j.bcp.2021.114868

PMCID:: PMC9248268

Abstract Article PDF–947K

Select item 898661811.

Protein Tyrosine Phosphatase Receptor δ Serves as the Orexigenic Asprosin Receptor

Ila Mishra, Wei Rose Xie, Juan C. Bournat, Yang He, Chunmei Wang, Elizabeth Sabath Silva, Hailan Liu, Zhiqiang Ku, Yinghua Chen, Bernadette O. Erokwu, Peilin Jia, Zhongming Zhao, Zhiqiang An, Chris A. Flask, Yanlin He, Yong Xu, Atul R. Chopra

Cell Metab. Author manuscript; available in PMC 2023 Apr 5.

Published in final edited form as: Cell Metab. 2022 Apr 5; 34(4): 549–563.e8. Published online 2022 Mar 16. doi: 10.1016/j.cmet.2022.02.012

PMCID:: PMC8986618

Abstract Article PDF–1.3M

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 810017013.

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, Sindhu T. Mohanty, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D. Irving, Ana Beleza-Meireles, Fernando Rivadeneira, Emma Duncan, J. Brent Richards, David J. Adams, Christopher J. Lelliott, Robert Brink, Tri Giang Phan, John A. Eisman, David M. Evans, Eleftheria Zeggini, Paul A. Baldock, J. H. Duncan Bassett, Graham R. Williams, Peter I. Croucher

Nat Commun. 2021; 12: 2444. Published online 2021 May 5. doi: 10.1038/s41467-021-22517-1

PMCID:: PMC8100170

Abstract Article PDF–11M

Select item 796347414.

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR

Javier Emperador-Melero, Giovanni de Nola, Pascal S Kaeser

eLife. 2021; 10: e66638. Published online 2021 Mar 3. doi: 10.7554/eLife.66638

PMCID:: PMC7963474

Abstract Article PDF–2.2M

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 730145216.

Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses

Kyung Ah Han, Hee-Yoon Lee, Dongseok Lim, Jungsu Shin, Taek Han Yoon, Xinran Liu, Ji Won Um, Se-Young Choi, Jaewon Ko

Mol Brain. 2020; 13: 94. Published online 2020 Jun 17. doi: 10.1186/s13041-020-00629-x

PMCID:: PMC7301452

Abstract Article PDF–2.8M

Select item 726524717.

Splice‐dependent trans‐synaptic PTPδ–IL1RAPL1 interaction regulates synapse formation and non‐REM sleep

Haram Park, Yeonsoo Choi, Hwajin Jung, Seoyeong Kim, Suho Lee, Hyemin Han, Hanseul Kweon, Suwon Kang, Woong Seob Sim, Frank Koopmans, Esther Yang, Hyun Kim, August B Smit, Yong Chul Bae, Eunjoon Kim

EMBO J. 2020 Jun 2; 39(11): e104150. Published online 2020 Apr 29. doi: 10.15252/embj.2019104150

PMCID:: PMC7265247

Abstract Article PDF–4.8M

Select item 699616218.

Functional analysis of candidate genes from genome-wide association studies of hearing

Neil J. Ingham, Victoria Rook, Francesca Di Domenico, Elysia James, Morag A. Lewis, Giorgia Girotto, Annalisa Buniello, Karen P. Steel

Hear Res. 2020 Mar 1; 387: 107879. doi: 10.1016/j.heares.2019.107879

PMCID:: PMC6996162

Abstract Article PDF–9.5M

Select item 698482019.

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses

Alessandra Sclip, Thomas C Südhof

eLife. 2020; 9: e53406. Published online 2020 Jan 27. doi: 10.7554/eLife.53406

PMCID:: PMC6984820

Abstract Article PDF–3.7M

Select item 675835620.

Congenic Mapping of Alcohol and Pentobarbital Withdrawal Liability Loci to a <1 Centimorgan Interval of Murine Chromosome 4: Identification of Mpdz as a Candidate Gene

Christoph Fehr, Renee L. Shirley, John K. Belknap, John C. Crabbe, Kari J. Buck

J Neurosci. 2002 May 1; 22(9): 3730–3738. doi: 10.1523/JNEUROSCI.22-09-03730.2002

PMCID:: PMC6758356

Abstract Article PDF–458K

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