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Select item 111481871.

TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice

Hee Joo Kim, Jinsun Jang, Kunhee Na, Eun-Hui Lee, Hyeon-Jung Gu, Yoon Hee Lim, Seul-A Joo, Seung Eun Baek, Joo-Young Roh, Han-Joo Maeng, Yun Hak Kim, Young-Jae Lee, Byung-Chul Oh, YunJae Jung

Exp Mol Med. 2024 May; 56(5): 1164–1177. Published online 2024 May 1. doi: 10.1038/s12276-024-01225-y

PMCID:: PMC11148187

Abstract Article PDF–7.7M

Select item 109981342.

Targeting SLC22A5 fosters mitophagy inhibition-mediated macrophage immunity against septic acute kidney injury upon CD47-SIRPα axis blockade

Yu Jia, Jun-Hua Li, Bang-Chuan Hu, Xia Huang, Xi Yang, Yan-Yan Liu, Juan-Juan Cai, Xue Yang, Jun-Mei Lai, Ye Shen, Jing-Quan Liu, Hai-Ping Zhu, Xiang-Ming Ye, Shi-Jing Mo

Heliyon. 2024 Apr 15; 10(7): e26791. Published online 2024 Feb 22. doi: 10.1016/j.heliyon.2024.e26791

PMCID:: PMC10998134

Abstract Article PDF–2.5M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107999414.

Surfactant protein D prevents mucin overproduction in airway goblet cells via SIRPα

Kentaro Hata, Kazuya Tsubouchi, Kunihiro Suzuki, Daisuke Eto, Hiroyuki Ando, Toyoshi Yanagihara, Keiko Kan-o, Isamu Okamoto

Sci Rep. 2024; 14: 1799. Published online 2024 Jan 20. doi: 10.1038/s41598-024-52328-5

PMCID:: PMC10799941

Abstract Article PDF–2.3M

Select item 107693505.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 102441686.

Blocking the CD47-SIRPα interaction reverses the disease phenotype in a polycythemia vera mouse model

Veronika Lysenko, Patrick M. Schürch, Selma Tuzlak, Nicole Wildner-Verhey van Wijk, Larisa V. Kovtonyuk, Burkhard Becher, Markus G. Manz, Stefanie Kreutmair, Alexandre P. A. Theocharides

Leukemia. 2023; 37(6): 1277–1286. Published online 2023 Apr 24. doi: 10.1038/s41375-023-01903-2

PMCID:: PMC10244168

Abstract Article PDF–3.1M

Select item 100100477.

SIRPα Mediates IGF1 Receptor in Cardiomyopathy-Induced by Chronic Kidney Disease

Sandhya S. Thomas, Jiao Wu, Giovanni Davogustto, Michael W. Holliday, Kristen Eckel-Mahan, Daniela Verzola, Giacomo Garibotto, Zhaoyong Hu, William E. Mitch, Heinrich Taegtmeyer

Circ Res. Author manuscript; available in PMC 2023 Jul 22.

Published in final edited form as: Circ Res. 2022 Jul 22; 131(3): 207–221. Published online 2022 Jun 20. doi: 10.1161/CIRCRESAHA.121.320546

PMCID:: PMC10010047

Abstract Article PDF–2.2M

Select item 97720378.

Neuronal signal regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina

Danye Jiang, Courtney A. Burger, Viktor Akhanov, Justine H. Liang, Robert D. Mackin, Nicholas E. Albrecht, Pilar Andrade, Dorothy P. Schafer, Melanie A. Samuel

Immunity. Author manuscript; available in PMC 2023 Dec 13.

Published in final edited form as: Immunity. 2022 Dec 13; 55(12): 2318–2335.e7. Published online 2022 Nov 14. doi: 10.1016/j.immuni.2022.10.018

PMCID:: PMC9772037

Abstract Article PDF–5.4M

Select item 97325259.

Loss of myeloid cell-specific SIRPα, but not CD47, attenuates inflammation and suppresses atherosclerosis

Bhupesh Singla, Hui-Ping Lin, WonMo Ahn, Jiean Xu, Qian Ma, Moses Sghayyer, Kunzhe Dong, Mary Cherian-Shaw, Jiliang Zhou, Yuqing Huo, Joseph White, Gábor Csányi

Cardiovasc Res. 2022 Nov; 118(15): 3097–3111. Published online 2021 Dec 23. doi: 10.1093/cvr/cvab369

PMCID:: PMC9732525

Abstract Article PDF–2.9M

Select item 968234410.

CD47 restricts antiviral function of alveolar macrophages during influenza virus infection

Christina Wenzek, Philine Steinbach, Florian Wirsdörfer, Kathrin Sutter, Julia D. Boehme, Robert Geffers, Robert Klopfleisch, Dunja Bruder, Verena Jendrossek, Jan Buer, Astrid M. Westendorf, Torben Knuschke

iScience. 2022 Dec 22; 25(12): 105540. Published online 2022 Nov 11. doi: 10.1016/j.isci.2022.105540

PMCID:: PMC9682344

Abstract Article PDF–2.6M

Select item 953542711.

SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis

Di Wang, Yunkai Lin, Feihong Xu, Hui Zhang, Xiaoyan Zhu, Zhen Liu, Yuan Hu, Guanjun Dong, Bingqi Sun, Yanhong Yu, Guoren Ma, Zhigang Tang, Diana Legarda, Adrian Ting, Yuan Liu, Jia Hou, Liwei Dong, Huabao Xiong

eBioMedicine. 2022 Nov; 85: 104278. Published online 2022 Oct 3. doi: 10.1016/j.ebiom.2022.104278

PMCID:: PMC9535427

Abstract Article PDF–5.0M

Select item 913362012.

Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis

Qinjun Shen, Li Zhao, Linyue Pan, Dandan Li, Gang Chen, Zhihong Chen, Zhilong Jiang

Front Immunol. 2022; 13: 865579. Published online 2022 May 12. doi: 10.3389/fimmu.2022.865579

PMCID:: PMC9133620

Abstract Article PDF–8.0M

Select item 907126513.

Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells

Boyang Ren, Huan Xia, Yijun Liao, Hang Zhou, Zhongnan Wang, Yaoyao Shi, Mingzhao Zhu

eLife. 2022; 11: e69219. Published online 2022 May 5. doi: 10.7554/eLife.69219

PMCID:: PMC9071265

Abstract Article PDF–1.5M

Select item 900476914.

SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen

Anu Autio, Huan Wang, Francisco Velázquez, Gail Newton, Charles A. Parkos, Pablo Engel, Daniel Engelbertsen, Andrew H. Lichtman, Francis W. Luscinskas

PLoS One. 2022; 17(4): e0266566. Published online 2022 Apr 12. doi: 10.1371/journal.pone.0266566

PMCID:: PMC9004769

Abstract Article PDF–2.5M

Select item 866914415.

Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha

Karen De Vlaminck, Ema Romão, Janik Puttemans, Ana Rita Pombo Antunes, Daliya Kancheva, Isabelle Scheyltjens, Jo A. Van Ginderachter, Serge Muyldermans, Nick Devoogdt, Kiavash Movahedi, Geert Raes

Front Immunol. 2021; 12: 777524. Published online 2021 Nov 30. doi: 10.3389/fimmu.2021.777524

PMCID:: PMC8669144

Abstract Article PDF–7.9M

Select item 840998916.

Augmentation of CD47/SIRPα signaling protects cones in genetic models of retinal degeneration

Sean K. Wang, Yunlu Xue, Constance L. Cepko

JCI Insight. 2021 Aug 23; 6(16): e150796. Published online 2021 Aug 23. doi: 10.1172/jci.insight.150796

PMCID:: PMC8409989

Abstract Article PDF–1.8M

Select item 836989417.

Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection

Lamin B. Cham, Laughing Bear Torrez Dulgeroff, Michal Caspi Tal, Tom Adomati, Fanghui Li, Hilal Bhat, Anfei Huang, Philipp A. Lang, Mary E. Moreno, Jose M. Rivera, Sofiya A. Galkina, Galina Kosikova, Cheryl A. Stoddart, Joseph M. McCune, Lara M. Myers, Irving L. Weissman, Karl S. Lang, Kim J. Hasenkrug

Cell Rep. Author manuscript; available in PMC 2021 Aug 17.

Published in final edited form as: Cell Rep. 2020 Apr 14; 31(2): 107494. doi: 10.1016/j.celrep.2020.03.058

PMCID:: PMC8369894

Abstract Article PDF–1.1M

Select item 831323918.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 821125519.

Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways

Nicolás Sarute, Han Cheng, Zhonghao Yan, Karen Salas-Briceno, Justin Richner, Lijun Rong, Susan R. Ross

PLoS Pathog. 2021 Jun; 17(6): e1009662. Published online 2021 Jun 7. doi: 10.1371/journal.ppat.1009662

PMCID:: PMC8211255

Abstract Article PDF–1.8M

Select item 816388420.

Intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells under radiotherapy

Zhen Bian, Lei Shi, Koby Kidder, Ke Zen, Charlie Garnett-Benson, Yuan Liu

Nat Commun. 2021; 12: 3229. Published online 2021 May 28. doi: 10.1038/s41467-021-23442-z

PMCID:: PMC8163884

Abstract Article PDF–4.4M

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