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Items: 1 to 20 of 53

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
Hyoseon Oh, Suho Lee, Yusang Oh, Seongbin Kim, Young Seo Kim, Yeji Yang, Woochul Choi, Ye-Eun Yoo, Heejin Cho, Seungjoon Lee, Esther Yang, Wuhyun Koh, Woojin Won, Ryunhee Kim, C. Justin Lee, Hyun Kim, Hyojin Kang, Jin Young Kim, Taeyun Ku, Se-Bum Paik, Eunjoon Kim
Nat Commun. 2023; 14: 3547. Published online 2023 Jun 15. doi: 10.1038/s41467-023-39203-z
PMCID:
PMC10272139
AbstractArticlePDF–4.3M
4.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
5.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
6.
Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse
Carmen Cifuentes-Diaz, Giorgia Canali, Marta Garcia, Mélanie Druart, Taylor Manett, Mythili Savariradjane, Camille Guillaume, Corentin Le Magueresse, Laurence Goutebroze
Front Neurosci. 2023; 17: 1100121. Published online 2023 Jan 30. doi: 10.3389/fnins.2023.1100121
PMCID:
PMC9922869
AbstractArticlePDF–6.4M
7.
Sound Localization in Preweanling Mice Was More Severely Affected by Deleting the Kcna1 Gene Compared to Deleting Kcna2, and a Curious Inverted-U Course of Development That Appeared to Exceed Adult Performance Was Observed in All Groups
James R. Ison, Paul D. Allen, Bruce L. Tempel, Helen M. Brew
J Assoc Res Otolaryngol. 2019 Dec; 20(6): 565–577. Published online 2019 Aug 13. doi: 10.1007/s10162-019-00731-5
PMCID:
PMC6889093
AbstractArticlePDF–659K
8.
Heteromultimeric Delayed-Rectifier K+ Channels in Schwann Cells: Developmental Expression and Role in Cell Proliferation
Alexander Sobko, Asher Peretz, Orian Shirihai, Sarah Etkin, Vera Cherepanova, Daniel Dagan, Bernard Attali
J Neurosci. 1998 Dec 15; 18(24): 10398–10408. doi: 10.1523/JNEUROSCI.18-24-10398.1998
PMCID:
PMC6793353
AbstractArticlePDF–470K
9.
CNS Myelin Paranodes Require Nkx6-2 Homeoprotein Transcriptional Activity for Normal Structure
Cherie Southwood, Chris He, James Garbern, John Kamholz, Edgardo Arroyo, Alexander Gow
J Neurosci. 2004 Dec 15; 24(50): 11215–11225. doi: 10.1523/JNEUROSCI.3479-04.2004
PMCID:
PMC6730372
AbstractArticlePDF–828K
10.
Mice Lacking Sodium Channel β1 Subunits Display Defects in Neuronal Excitability, Sodium Channel Expression, and Nodal Architecture
Chunling Chen, Ruth E. Westenbroek, Xiaorong Xu, Chris A. Edwards, Dorothy R. Sorenson, Yuan Chen, Dyke P. McEwen, Heather A. O'Malley, Vandana Bharucha, Laurence S. Meadows, Gabriel A. Knudsen, Alex Vilaythong, Jeffrey L. Noebels, Thomas L. Saunders, Todd Scheuer, Peter Shrager, William A. Catterall, Lori L. Isom
J Neurosci. 2004 Apr 21; 24(16): 4030–4042. doi: 10.1523/JNEUROSCI.4139-03.2004
PMCID:
PMC6729427
AbstractArticlePDF–1.0M
11.
Altered Distribution of Juxtaparanodal Kv1.2 Subunits Mediates Peripheral Nerve Hyperexcitability in Type 2 Diabetes Mellitus
Jennifer Zenker, Olivier Poirot, Anne-Sophie de Preux Charles, Estelle Arnaud, Jean-Jacques Médard, Catherine Lacroix, Thierry Kuntzer, Roman Chrast
J Neurosci. 2012 May 30; 32(22): 7493–7498. doi: 10.1523/JNEUROSCI.0719-12.2012
PMCID:
PMC6703576
AbstractArticlePDF–1.1M
12.
Contribution of DNMT1 to Neuropathic Pain Genesis Partially through Epigenetically Repressing Kcna2 in Primary Afferent Neurons
Linlin Sun, Xiyao Gu, Zhiqiang Pan, Xinying Guo, Jianbin Liu, Fidelis E. Atianjoh, Shaogen Wu, Kai Mo, Bo Xu, Lingli Liang, Alex Bekker, Yuan-Xiang Tao
J Neurosci. 2019 Aug 14; 39(33): 6595–6607. doi: 10.1523/JNEUROSCI.0695-19.2019
PMCID:
PMC6697395
AbstractArticlePDF–2.5M
13.
A Common Ankyrin-G-Based Mechanism Retains KCNQ and NaV Channels at Electrically Active Domains of the Axon
Zongming Pan, Tingching Kao, Zsolt Horvath, Julia Lemos, Jai-Yoon Sul, Stephen D. Cranstoun, Vann Bennett, Steven S. Scherer, Edward C. Cooper
J Neurosci. 2006 Mar 8; 26(10): 2599–2613. doi: 10.1523/JNEUROSCI.4314-05.2006
PMCID:
PMC6675151
AbstractArticlePDF–2.4M
14.
The Expression of TAG-1 in Glial Cells Is Sufficient for the Formation of the Juxtaparanodal Complex and the Phenotypic Rescue of Tag-1 Homozygous Mutants in the CNS
Maria Savvaki, Kostas Theodorakis, Lida Zoupi, Antonis Stamatakis, Simona Tivodar, Kyriacos Kyriacou, Fotini Stylianopoulou, Domna Karagogeos
J Neurosci. 2010 Oct 20; 30(42): 13943–13954. doi: 10.1523/JNEUROSCI.2574-10.2010
PMCID:
PMC6634759
AbstractArticlePDF–1.8M
15.
Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain
H Wang, DD Kunkel, PA Schwartzkroin, BL Tempel
J Neurosci. 1994 Aug 1; 14(8): 4588–4599. doi: 10.1523/JNEUROSCI.14-08-04588.1994
PMCID:
PMC6577177
AbstractPDF–11M
16.
MBD1 Contributes to the Genesis of Acute Pain and Neuropathic Pain by Epigenetic Silencing of Oprm1 and Kcna2 Genes in Primary Sensory Neurons
Kai Mo, Shaogen Wu, Xiyao Gu, Ming Xiong, Weihua Cai, Fidelis E. Atianjoh, Emily E. Jobe, Xinyu Zhao, Wei-Feng Tu, Yuan-Xiang Tao
J Neurosci. 2018 Nov 14; 38(46): 9883–9899. doi: 10.1523/JNEUROSCI.0880-18.2018
PMCID:
PMC6234297
AbstractArticlePDF–2.6M
17.
Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations
Victoria A. Baronas, Runying Y. Yang, Luis Carlos Morales, Simonetta Sipione, Harley T. Kurata
Nat Commun. 2018; 9: 4417. Published online 2018 Oct 24. doi: 10.1038/s41467-018-06859-x
PMCID:
PMC6200743
AbstractArticlePDF–2.0M
18.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
19.
Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning
Maria Christina Sergaki, Juan Carlos López-Ramos, Stefanos Stagkourakis, Agnès Gruart, Christian Broberger, José María Delgado-García, Carlos F. Ibáñez
Cell Rep. 2017 Jun 6; 19(10): 1977–1986. Published online 2017 Jun 6. doi: 10.1016/j.celrep.2017.05.030
PMCID:
PMC5469938
AbstractArticle
20.
Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness
Gregg W. Crabtree, Ziyi Sun, Mirna Kvajo, Jantine A.C. Broek, Karine Fénelon, Heather McKellar, Lan Xiao, Bin Xu, Sabine Bahn, James M. O'Donnell, Joseph A. Gogos
J Neurosci. 2017 Apr 12; 37(15): 4158–4180. doi: 10.1523/JNEUROSCI.4345-15.2017
PMCID:
PMC5391686
AbstractArticlePDF–5.2M

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