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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 103126742.

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker

Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560

Published in:: Mol Syst Biol. 2024 Apr; 20(4): 428–457.

PMCID:: PMC10312674

Abstract Article PDF–9.6M

Select item 100746573.

Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation

Juying Jiao, Linjie Ruan, Chien-shan Cheng, Fengjiao Wang, Peiwen Yang, Zhen Chen

Mol Med. 2023; 29: 47. Published online 2023 Apr 4. doi: 10.1186/s10020-023-00648-z

PMCID:: PMC10074657

Abstract Article PDF–10M

Select item 100729064.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 99224685.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 97507666.

Expression and Prognostic Value of PIK3CA, VEGF, IL-8, IL-10, and RIP2 in Diffuse Large B-Cell Lymphoma

Na Shen, Yanfang Yu, Ruiying Zhang, Ying Guo, Mei Liu, Mengtian Tan, Jianxia Liu, Jing Bai, Li Li, Keyu Liu, Ran Wang, Jinglan He

Int J Clin Pract. 2022; 2022: 2637581. Published online 2022 Dec 7. doi: 10.1155/2022/2637581

PMCID:: PMC9750766

Abstract Article PDF–273K

Select item 97137187.

Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection

Subhash Mehto, Kautilya Kumar Jena, Rina Yadav, Swatismita Priyadarsini, Pallavi Samal, Sivaram Krishna, Kollori Dhar, Ashish Jain, Nishant Ranjan Chauhan, Krushna C Murmu, Ramyasingh Bal, Rinku Sahu, Pundrik Jaiswal, Bhabani Sankar Sahoo, Srinivas Patnaik, Thomas A Kufer, Tor Erik Rusten, Swati Chauhan, Punit Prasad, Santosh Chauhan

EMBO J. 2022 Dec; 41(23): e111289. Published online 2022 Oct 11. doi: 10.15252/embj.2022111289

PMCID:: PMC9713718

Abstract Article PDF–14M

Select item 96290778.

The Crohn Disease-associated ATG16L1^T300A polymorphism regulates inflammatory responses by modulating TLR- and NLR-mediated signaling

Ping Gao, Hongtao Liu, Huarong Huang, Yu Sun, Baoqian Jia, Baidong Hou, Xuyu Zhou, Warren Strober, Fuping Zhang

Autophagy. 2022; 18(11): 2561–2575. Published online 2022 Feb 27. doi: 10.1080/15548627.2022.2039991

PMCID:: PMC9629077

Abstract Article PDF–2.8M

Select item 96273709.

Mechanism of RIP2 enhancing stemness of glioma cells induces temozolomide resistance

Xiao‐liang Wang, Bao‐hua Jiao, Jian‐liang Wu, Jian‐kai Yang, Yu‐hua Hu, Kai Cui

CNS Neurosci Ther. 2022 Dec; 28(12): 2319–2330. Published online 2022 Oct 2. doi: 10.1111/cns.13981

PMCID:: PMC9627370

Abstract Article PDF–12M

Select item 917169010.

XIAP promotes melanoma growth by inducing tumour neutrophil infiltration

Mila Daoud, Pia Nora Broxtermann, Fabian Schorn, J Paul Werthenbach, Jens Michael Seeger, Lars M Schiffmann, Kerstin Brinkmann, Domagoj Vucic, Thomas Tüting, Cornelia Mauch, Dagmar Kulms, Paola Zigrino, Hamid Kashkar

EMBO Rep. 2022 Jun; 23(6): e53608. Published online 2022 Apr 19. doi: 10.15252/embr.202153608

PMCID:: PMC9171690

Abstract Article PDF–2.1M

Select item 910523511.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 906689512.

Pan-cancer analysis reveals RIPK2 predicts prognosis and promotes immune therapy resistance via triggering cytotoxic T lymphocytes dysfunction

Junquan Song, Runyu Yang, Rongyuan Wei, Yue Du, Pengcheng He, Xiaowen Liu

Mol Med. 2022; 28: 47. Published online 2022 May 4. doi: 10.1186/s10020-022-00475-8

PMCID:: PMC9066895

Abstract Article PDF–6.9M

Select item 904479613.

High expression of RIPK2 is associated with Taxol resistance in serous ovarian cancer

Yuqing Shen, Hui Lin, Kelie Chen, Wanzhong Ge, Dajing Xia, Yihua Wu, Weiguo Lu

J Ovarian Res. 2022; 15: 48. Published online 2022 Apr 27. doi: 10.1186/s13048-022-00986-2

PMCID:: PMC9044796

Abstract Article PDF–4.0M

Select item 904026814.

A pancancer analysis of the carcinogenic role of receptor-interacting serine/threonine protein kinase-2 (RIPK2) in human tumours

Hanqun Zhang, Yan Ma, Qiuning Zhang, Ruifeng Liu, Hongtao Luo, Xiaohu Wang

BMC Med Genomics. 2022; 15: 97. Published online 2022 Apr 26. doi: 10.1186/s12920-022-01239-3

PMCID:: PMC9040268

Abstract Article PDF–2.2M

Select item 899871215.

Transcriptional Regulation of RIP2 Gene by NFIB Is Associated with Cellular Immune and Inflammatory Response to APEC Infection

Hongyan Sun, Naying Li, Jishuang Tan, Huan Li, Jibin Zhang, Lujiang Qu, Susan J. Lamont

Int J Mol Sci. 2022 Apr; 23(7): 3814. Published online 2022 Mar 30. doi: 10.3390/ijms23073814

PMCID:: PMC8998712

Abstract Article PDF–4.9M

Select item 881392516.

Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis

Yiwu Yan, Bo Zhou, Chen Qian, Alex Vasquez, Mohini Kamra, Avradip Chatterjee, Yeon-Joo Lee, Xiaopu Yuan, Leigh Ellis, Dolores Di Vizio, Edwin M. Posadas, Natasha Kyprianou, Beatrice S. Knudsen, Kavita Shah, Ramachandran Murali, Arkadiusz Gertych, Sungyong You, Michael R. Freeman, Wei Yang

Nat Commun. 2022; 13: 669. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28340-6

PMCID:: PMC8813925

Abstract Article PDF–7.6M

Select item 840959117.

Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response

Kishu Ranjan, Matija Hedl, Saloni Sinha, Xuchen Zhang, Clara Abraham

J Clin Invest. 2021 Sep 1; 131(17): e145472. Published online 2021 Sep 1. doi: 10.1172/JCI145472

PMCID:: PMC8409591

Abstract Article PDF–18M

Select item 830333018.

Receptor-Interacting Serine/Threonine-Protein Kinase-2 as a Potential Prognostic Factor in Colorectal Cancer

Rola F. Jaafar, Zeid Ibrahim, Karim Ataya, Joelle Hassanieh, Natasha Ard, Walid Faraj

Medicina (Kaunas) 2021 Jul; 57(7): 709. Published online 2021 Jul 14. doi: 10.3390/medicina57070709

PMCID:: PMC8303330

Abstract Article PDF–706K

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 806420920.

RIPK2 is an unfavorable prognosis marker and a potential therapeutic target in human kidney renal clear cell carcinoma

Diangeng Li, Liangyou Tang, Bo Liu, Shibo Xu, Meiling Jin, Wu Bo

Aging (Albany NY) 2021 Apr 15; 13(7): 10450–10467. Published online 2021 Mar 31. doi: 10.18632/aging.202808

PMCID:: PMC8064209

Abstract Article PDF–2.3M

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