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Select item 112260871.

Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection

Aleksandra K. Drelich, Kempaiah Rayavara, Jason Hsu, Panatda Saenkham-Huntsinger, Barbara M. Judy, Vivian Tat, Thomas G. Ksiazek, Bi-Hung Peng, Chien-Te K. Tseng

PLoS Pathog. 2024 Jun; 20(6): e1011777. Published online 2024 Jun 24. doi: 10.1371/journal.ppat.1011777

PMCID:: PMC11226087

Abstract Article PDF–2.1M

Select item 112211852.

Reduction in ACE2 expression in peripheral blood mononuclear cells during COVID-19 – implications for post COVID-19 conditions

Gulrayz Ahmed, Yasir Abdelgadir, Amro Abdelghani, Pippa Simpson, Jody Barbeau, Donald Basel, Christy S. Barrios, Brandon A Smith, Kala F Schilter, Rupa Udani, Honey V. Reddi, Rodney E. Willoughby

BMC Infect Dis. 2024; 24: 663. Published online 2024 Jul 3. doi: 10.1186/s12879-024-09321-0

PMCID:: PMC11221185

Abstract Article PDF–1.0M

Select item 111987573.

ACE gene polymorphism and susceptibility to hypertension in a Jordanian adult population

Laith AL-Eitan, Sara Al-Khaldi, Rasheed k. Ibdah

PLoS One. 2024; 19(6): e0304271. Published online 2024 Jun 25. doi: 10.1371/journal.pone.0304271

PMCID:: PMC11198757

Abstract Article PDF–617K

Select item 111574564.

Association of specific ACE2 and TMPRSS2 variants with circulatory cytokines of COVID-19 Emirati patients

Noha M. Elemam, Amal Bouzid, Habiba Alsafar, Samrein BM Ahmed, Shirin Hafezi, Thenmozhi Venkatachalam, Leen Eldohaji, Tasneem Al Hamidi, Peter Habib Gerges, Nour Halabi, Hassen Hadj-Kacem, Iman M. Talaat, Jalal Taneera, Nabil Sulaiman, Azzam A. Maghazachi, Qutayba Hamid, Rifat Hamoudi, Maha Saber-Ayad

Front Immunol. 2024; 15: 1348229. Published online 2024 May 24. doi: 10.3389/fimmu.2024.1348229

PMCID:: PMC11157456

Abstract Article PDF–5.9M

Select item 111572635.

Association of ACE2 and TMPRSS2 genes variants with disease severity and most important biomarkers in COVID-19 patients in Bosnia and Herzegovina

Neven Meseldžić, Besim Prnjavorac, Tanja Dujić, Maja Malenica, Una Glamočlija, Lejla Prnjavorac, Omer Bedak, Selma Imamović Kadrić, Damir Marjanović, Tamer Bego

Croat Med J. 2024 Jun; 65(3): 220–232. doi: 10.3325/cmj.2024.65.220

PMCID:: PMC11157263

Abstract Article PDF–175K

Select item 111038876.

SARS-CoV-2 tropism to intestinal but not gastric epithelial cells is defined by limited ACE2 expression

Mindaugas Paužuolis, Diana Fatykhova, Boris Zühlke, Torsten Schwecke, Mastura Neyazi, Pilar Samperio-Ventayol, Carmen Aguilar, Nicolas Schlegel, Simon Dökel, Markus Ralser, Andreas Hocke, Christine Krempl, Sina Bartfeld

Stem Cell Reports. 2024 May 14; 19(5): 629–638. Published online 2024 Apr 25. doi: 10.1016/j.stemcr.2024.03.008

PMCID:: PMC11103887

Abstract Article PDF–4.8M

Select item 110860527.

Integrin β1 is a key determinant of the expression of angiotensin-converting enzyme 2 (ACE2) in the kidney epithelial cells

Md Saimon Mia, Delowar Hossain, Emerson Woodbury, Sean Kelleher, Riya. J. Palamuttam, Reena Rao, Preston Steen, Yagna PR Jarajapu, Sijo Mathew

Eur J Cell Biol. Author manuscript; available in PMC 2024 May 10.

Published in final edited form as: Eur J Cell Biol. 2023 Jun; 102(2): 151316. Published online 2023 Apr 18. doi: 10.1016/j.ejcb.2023.151316

PMCID:: PMC11086052

Abstract Article PDF–1.9M

Select item 110764798.

Genetic variations in ACE2 gene associated with metabolic syndrome in southern China: a case–control study

Min Pan, Mingzhong Yu, Suli Zheng, Li Luo, Jie Zhang, Jianmin Wu

Sci Rep. 2024; 14: 10505. Published online 2024 May 7. doi: 10.1038/s41598-024-61254-5

PMCID:: PMC11076479

Abstract Article PDF–1.5M

Select item 110397119.

FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection

Hao Meng, Zhiying Liao, Yanting Ji, Dong Wang, Yang Han, Chaolin Huang, Xujuan Hu, Jingyi Chen, Hengrui Zhang, Zonghong Li, Changliang Wang, Hui Sun, Jiaqi Sun, Lihua Chen, Jiaxiang Yin, Jincun Zhao, Tao Xu, Huisheng Liu

Signal Transduct Target Ther. 2024; 9: 104. Published online 2024 Apr 23. doi: 10.1038/s41392-024-01790-8

PMCID:: PMC11039711

Abstract Article PDF–5.0M

Select item 1100537510.

ACE-2-like enzymatic activity is associated with immunoglobulin in COVID-19 patients

Yufeng Song, Regan Myers, Frances Mehl, Lila Murphy, Bailey Brooks, Jeffrey M. Wilson, Alexandra Kadl, Judith Woodfolk, Steven L. Zeichner

mBio. 2024 Apr; 15(4): e00541-24. Published online 2024 Mar 19. doi: 10.1128/mbio.00541-24

PMCID:: PMC11005375

Abstract Article PDF–1.9M

Select item 1096327011.

High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2

Charles W. F. Chan, Bei Wang, Lang Nan, Xiner Huang, Tianjiao Mao, Hoi Yee Chu, Cuiting Luo, Hin Chu, Gigi C. G. Choi, Ho Cheung Shum, Alan S. L. Wong

Nat Biomed Eng. 2024; 8(3): 291–309. Published online 2023 Nov 23. doi: 10.1038/s41551-023-01140-z

Correction in:: Nat Biomed Eng. 2024; 8(3): 336.

PMCID:: PMC10963270

Abstract Article PDF–16M

Select item 1094203612.

Pathological changes in oral epithelium and the expression of SARS-CoV-2 entry receptors, ACE2 and furin

Osnat Grinstein-Koren, Michal Lusthaus, Hilla Tabibian-Keissar, Ilana Kaplan, Amos Buchner, Ron Ilatov, Marilena Vered, Ayelet Zlotogorski-Hurvitz

PLoS One. 2024; 19(3): e0300269. Published online 2024 Mar 15. doi: 10.1371/journal.pone.0300269

PMCID:: PMC10942036

Abstract Article PDF–2.2M

Select item 1092558813.

Serum ACE2 and S19P gene polymorphism in Egyptian patients with COVID-19 infection: correlation with disease severity

Dalia A. Gaber, Mohamed Shokr, Olfat Shaker, Kamelia Ahmed Zaki, Haidy Samir Khalil, Amany M. Wahb

Sci Rep. 2024; 14: 5846. Published online 2024 Mar 10. doi: 10.1038/s41598-024-56260-6

PMCID:: PMC10925588

Abstract Article PDF–1.2M

Select item 1089808214.

Nasopharyngeal angiotensin converting enzyme 2 (ACE2) expression as a risk-factor for SARS-CoV-2 transmission in concurrent hospital associated outbreaks

Aidan M. Nikiforuk, Kevin S. Kuchinski, Katy Short, Susan Roman, Mike A. Irvine, Natalie Prystajecky, Agatha N. Jassem, David M. Patrick, Inna Sekirov

BMC Infect Dis. 2024; 24: 262. Published online 2024 Feb 26. doi: 10.1186/s12879-024-09067-9

PMCID:: PMC10898082

Abstract Article PDF–1.8M

Select item 1087869115.

Transcriptional regulation of SARS-CoV-2 receptor ACE2 by SP1

Hui Han, Rong-Hua Luo, Xin-Yan Long, Li-Qiong Wang, Qian Zhu, Xin-Yue Tang, Rui Zhu, Yi-Cheng Ma, Yong-Tang Zheng, Cheng-Gang Zou

eLife. 2024; 13: e85985. Published online 2024 Feb 20. doi: 10.7554/eLife.85985

PMCID:: PMC10878691

Abstract Article PDF–3.6M

Select item 1081687016.

Differential Ability of Spike Protein of SARS-CoV-2 Variants to Downregulate ACE2

Yosuke Maeda, Mako Toyoda, Takeo Kuwata, Hiromi Terasawa, Umiru Tokugawa, Kazuaki Monde, Tomohiro Sawa, Takamasa Ueno, Shuzo Matsushita

Int J Mol Sci. 2024 Jan; 25(2): 1353. Published online 2024 Jan 22. doi: 10.3390/ijms25021353

PMCID:: PMC10816870

Abstract Article PDF–2.4M

Select item 1080715417.

Genetic association of ACE2 and TMPRSS2 polymorphisms with COVID-19 severity; a single centre study from Egypt

Marwa H. Elnagdy, Alshimaa Magdy, Waleed Eldars, Mohamed Elgamal, Ahmed Hazem El-Nagdy, Omnia Salem, Mohamed Magdy Elmowafy, Omar Ahmed Elborsh, Abdelrahman Walid Elshafey, Muhammad Magdy Kesba, Ahmed Elsaeed Abdulgalil, Ali Sobh

Virol J. 2024; 21: 27. Published online 2024 Jan 23. doi: 10.1186/s12985-024-02298-x

PMCID:: PMC10807154

Abstract Article PDF–1.5M

Select item 1080168618.

Two Receptor Binding Strategy of SARS-CoV-2 Is Mediated by Both the N-Terminal and Receptor-Binding Spike Domain

Michele Monti, Edoardo Milanetti, Myrthe T. Frans, Mattia Miotto, Lorenzo Di Rienzo, Maksim V. Baranov, Giorgio Gosti, Arun Kumar Somavarapu, Madhu Nagaraj, Thaddeus W. Golbek, Emiel Rossing, Sam J. Moons, Thomas J. Boltje, Geert van den Bogaart, Tobias Weidner, Daniel E. Otzen, Gian Gaetano Tartaglia, Giancarlo Ruocco, Steven J. Roeters

J Phys Chem B. 2024 Jan 18; 128(2): 451–464. Published online 2024 Jan 8. doi: 10.1021/acs.jpcb.3c06258

PMCID:: PMC10801686

Abstract Article PDF–6.0M

Select item 1079990319.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0