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Items: 1 to 20 of 40

1.
Nmnat1 Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1
Kazuhiro Hasegawa, Masanori Tamaki, Yusuke Sakamaki, Shu Wakino
Int J Mol Sci. 2024 Jun; 25(12): 6384. Published online 2024 Jun 9. doi: 10.3390/ijms25126384
PMCID:
PMC11204038
AbstractArticlePDF–17M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The mouse nicotinamide mononucleotide adenylyltransferase chaperones diverse pathological amyloid client proteins
Chengan Huang, Jinxia Lu, Xiaojuan Ma, Jiali Qiang, Chuchu Wang, Cong Liu, Yanshan Fang, Yaoyang Zhang, Lin Jiang, Dan Li, Shengnan Zhang
J Biol Chem. 2022 May; 298(5): 101912. Published online 2022 Apr 7. doi: 10.1016/j.jbc.2022.101912
PMCID:
PMC9108885
AbstractArticlePDF–3.3M
4.
Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons
David Sokolov, Emily R Sechrest, Yekai Wang, Connor Nevin, Jianhai Du, Saravanan Kolandaivelu
eLife. 2021; 10: e71185. Published online 2021 Dec 8. doi: 10.7554/eLife.71185
PMCID:
PMC8754432
AbstractArticlePDF–9.2M
5.
Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells
Xiangguo Shi, Yajian Jiang, Ayumi Kitano, Tianyuan Hu, Rebecca L. Murdaugh, Yuan Li, Kevin A. Hoegenauer, Rui Chen, Koichi Takahashi, Daisuke Nakada
Sci Adv. 2021 Jul; 7(30): eabf3895. Published online 2021 Jul 21. doi: 10.1126/sciadv.abf3895
PMCID:
PMC8294764
AbstractArticlePDF–691K
6.
Mutant Nmnat1 leads to a retina-specific decrease of NAD+ accompanied by increased poly(ADP-ribose) in a mouse model of NMNAT1-associated retinal degeneration
Scott H Greenwald, Emily E Brown, Michael J Scandura, Erin Hennessey, Raymond Farmer, Jianhai Du, Yekai Wang, Eric A Pierce
Hum Mol Genet. 2021 Apr 15; 30(8): 644–657. Published online 2021 Mar 11. doi: 10.1093/hmg/ddab070
PMCID:
PMC8127407
AbstractArticlePDF–1.0M
7.
SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration
Yo Sasaki, Hiroki Kakita, Shunsuke Kubota, Abdoulaye Sene, Tae Jun Lee, Norimitsu Ban, Zhenyu Dong, Joseph B Lin, Sanford L Boye, Aaron DiAntonio, Shannon E Boye, Rajendra S Apte, Jeffrey Milbrandt
eLife. 2020; 9: e62027. Published online 2020 Oct 27. doi: 10.7554/eLife.62027
PMCID:
PMC7591247
AbstractArticlePDF–2.6M
8.
Functional Interplay between Histone H2B ADP-ribosylation and Phosphorylation Controls Adipogenesis
Dan Huang, Cristel V. Camacho, Rohit Setlem, Keun Woo Ryu, Balaji Parameswaran, Rana K. Gupta, W. Lee Kraus
Mol Cell. Author manuscript; available in PMC 2021 Sep 17.
Published in final edited form as: Mol Cell. 2020 Sep 17; 79(6): 934–949.e14. Published online 2020 Aug 20. doi: 10.1016/j.molcel.2020.08.002
PMCID:
PMC7502539
AbstractArticlePDF–2.8M
9.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
10.
Rescue of Peripheral and CNS Axon Defects in Mice Lacking NMNAT2
Jonathan Gilley, Robert Adalbert, Gang Yu, Michael P. Coleman
J Neurosci. 2013 Aug 14; 33(33): 13410–13424. doi: 10.1523/JNEUROSCI.1534-13.2013
PMCID:
PMC6705152
AbstractArticlePDF–6.2M
11.
Stimulation of Nicotinamide Adenine Dinucleotide Biosynthetic Pathways Delays Axonal Degeneration after Axotomy
Yo Sasaki, Toshiyuki Araki, Jeffrey Milbrandt
J Neurosci. 2006 Aug 16; 26(33): 8484–8491. doi: 10.1523/JNEUROSCI.2320-06.2006
PMCID:
PMC6674352
AbstractArticlePDF–531K
12.
Nicotinamide Mononucleotide Adenylyltransferase Expression in Mitochondrial Matrix Delays Wallerian Degeneration
Naoki Yahata, Shigeki Yuasa, Toshiyuki Araki
J Neurosci. 2009 May 13; 29(19): 6276–6284. doi: 10.1523/JNEUROSCI.4304-08.2009
PMCID:
PMC6665489
AbstractArticlePDF–517K
13.
Non-Nuclear WldS Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo
Bogdan Beirowski, Elisabetta Babetto, Jon Gilley, Francesca Mazzola, Laura Conforti, Lucie Janeckova, Giulio Magni, Richard R. Ribchester, Michael P. Coleman
J Neurosci. 2009 Jan 21; 29(3): 653–668. doi: 10.1523/JNEUROSCI.3814-08.2009
PMCID:
PMC6665162
AbstractArticlePDF–1.3M
14.
Metabolic Regulation of Transcription Through Compartmentalized NAD+ Biosynthesis
Keun Woo Ryu, Tulip Nandu, Jiyeon Kim, Sridevi Challa, Ralph J. DeBerardinis, W. Lee Kraus
Science. Author manuscript; available in PMC 2019 May 11.
Published in final edited form as: Science. 2018 May 11; 360(6389): eaan5780. doi: 10.1126/science.aan5780
PMCID:
PMC6465534
AbstractArticlePDF–1.0M
15.
NMNAT Proteins that Limit Wallerian Degeneration Also Regulate Critical Period Plasticity in the Visual Cortex
Mariska van Lier, Laura Smit-Rigter, Roos Krimpenfort, M. Hadi Saiepour, Emma Ruimschotel, Willem Kamphuis, J. Alexander Heimel, Christiaan N. Levelt
eNeuro. 2019 Jan-Feb; 6(1): ENEURO.0277-18.2018. Prepublished online 2019 Jan 4. Published online 2019 Jan 18. doi: 10.1523/ENEURO.0277-18.2018
PMCID:
PMC6338469
AbstractArticlePDF–1.9M
16.
Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation
Hiroshi Kuribayashi, Yukihiro Baba, Toshiro Iwagawa, Eisuke Arai, Akira Murakami, Sumiko Watanabe
Cell Death Dis. 2018 Sep; 9(9): 891. Published online 2018 Aug 30. doi: 10.1038/s41419-018-0907-0
PMCID:
PMC6117278
AbstractArticlePDF–3.3M
17.
NMNAT1 E257K Variant, Associated with Leber Congenital Amaurosis (LCA9), Causes a Mild Retinal Degeneration Phenotype
Aiden Eblimit, Smriti Agrawal Zaneveld, Wei Liu, Kandace Thomas, Keqing Wang, Yumei Li, Graeme Mardon, Rui Chen
Exp Eye Res. Author manuscript; available in PMC 2019 Aug 1.
Published in final edited form as: Exp Eye Res. 2018 Aug; 173: 32–43. Published online 2018 Apr 17. doi: 10.1016/j.exer.2018.04.010
PMCID:
PMC6054811
AbstractArticlePDF–1.5M
18.
NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy
Francesca Rossi, Philippine C. Geiszler, Weina Meng, Matthew R. Barron, Malcolm Prior, Anna Herd-Smith, Andrea Loreto, Maria Yanez Lopez, Henryk Faas, Marie-Christine Pardon, Laura Conforti
Behav Brain Res. 2018 Feb 26; 339: 140–152. doi: 10.1016/j.bbr.2017.11.030
PMCID:
PMC5769520
AbstractArticle
19.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
20.
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion
Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt
eLife. 2016; 5: e19749. Published online 2016 Oct 13. doi: 10.7554/eLife.19749
PMCID:
PMC5063586
AbstractArticlePDF–1.9M

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