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Select item 114658191.

TMEM132A regulates Wnt/β-catenin signaling through stabilizing LRP6 during mouse embryonic development

Shin Ae Oh, Jiyeon Jeon, Su-yeon Je, Seoyoung Kim, Joohyun Jung, Hyuk Wan Ko

Cell Commun Signal. 2024; 22: 482. Published online 2024 Oct 9. doi: 10.1186/s12964-024-01855-9

PMCID:: PMC11465819

Abstract Article PDF–3.0M

Select item 110674672.

Core planar cell polarity genes VANGL1 and VANGL2 in predisposition to congenital vertebral malformations

Xin Feng, Yongyu Ye, Jianan Zhang, Yuanqiang Zhang, Sen Zhao, Judith C. W. Mak, Nao Otomo, Zhengye Zhao, Yuchen Niu, Yoshiro Yonezawa, Guozhuang Li, Mao Lin, Xiaoxin Li, Prudence Wing Hang Cheung, Kexin Xu, Kazuki Takeda, Shengru Wang, Junjie Xie, Toshiaki Kotani, Vanessa N. T. Choi, You-Qiang Song, Yang Yang, Keith Dip Kei Luk, Kin Shing Lee, Ziquan Li, Pik Shan Li, Connie Y. H. Leung, Xiaochen Lin, Xiaolu Wang, Guixing Qiu, DISCO (Deciphering disorders Involving Scoliosis and COmorbidities) study group, Kota Watanabe, Japanese Early Onset Scoliosis Research Group, Zhihong Wu, Jennifer E. Posey, Shiro Ikegawa, James R. Lupski, Jason Pui Yin Cheung, Terry Jianguo Zhang, Bo Gao, Nan Wu

Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2310283121. Published online 2024 Apr 26. doi: 10.1073/pnas.2310283121

PMCID:: PMC11067467

Abstract Article PDF–11M

Select item 109464403.

Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm

Matthew P. Pappas, Hiroko Kawakami, Dylan Corcoran, Katherine Q. Chen, Earl Parker Scott, Julia Wong, Micah D. Gearhart, Ryuichi Nishinakamura, Yasushi Nakagawa, Yasuhiko Kawakami

Development. 2024 Mar 1; 151(5): dev202649. Published online 2024 Mar 4. doi: 10.1242/dev.202649

PMCID:: PMC10946440

Abstract Article

Select item 103359374.

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner

Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6

PMCID:: PMC10335937

Abstract Article PDF–25M

Select item 100796775.

Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis

Yudai Hatakeyama, Nen Saito, Yusuke Mii, Ritsuko Takada, Takuma Shinozuka, Tatsuya Takemoto, Honda Naoki, Shinji Takada

Nat Commun. 2023; 14: 1924. Published online 2023 Apr 6. doi: 10.1038/s41467-023-37350-x

PMCID:: PMC10079677

Abstract Article PDF–12M

Select item 97718196.

Primate gastrulation and early organogenesis at single-cell resolution

Jinglei Zhai, Jing Guo, Haifeng Wan, Luqing Qi, Lizhong Liu, Zhenyu Xiao, Long Yan, Daniel A. Schmitz, Yanhong Xu, Dainan Yu, Xulun Wu, Wentao Zhao, Kunyuan Yu, Xiangxiang Jiang, Fan Guo, Jun Wu, Hongmei Wang

Nature. 2022; 612(7941): 732–738. Published online 2022 Dec 14. doi: 10.1038/s41586-022-05526-y

PMCID:: PMC9771819

Abstract Article PDF–19M

Select item 95344137.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 94851618.

A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production

Naomi R. Genuth, Zhen Shi, Koshi Kunimoto, Victoria Hung, Adele F. Xu, Craig H. Kerr, Gerald C. Tiu, Juan A. Oses-Prieto, Rachel E. A. Salomon-Shulman, Jeffrey D. Axelrod, Alma L. Burlingame, Kyle M. Loh, Maria Barna

Nat Commun. 2022; 13: 5491. Published online 2022 Sep 19. doi: 10.1038/s41467-022-33263-3

PMCID:: PMC9485161

Abstract Article PDF–3.6M

Select item 94823349.

TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration

Binbin Li, Liza Brusman, Jacob Dahlka, Lee A. Niswander

Development. 2022 Sep 1; 149(17): dev200442. Published online 2022 Aug 30. doi: 10.1242/dev.200442

PMCID:: PMC9482334

Abstract Article

Select item 938211710.

A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation

Tingxu Chen, Heather Alcorn, Sujan Devbhandari, Dirk Remus, Elizabeth Lacy, Danwei Huangfu, Kathryn V. Anderson

Biol Open. 2022 Aug 15; 11(8): bio059307. Published online 2022 Aug 8. doi: 10.1242/bio.059307

PMCID:: PMC9382117

Abstract Article PDF–10M

Select item 919448211.

The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice

Tianyu Zhao, Moira McMahon, Kurt Reynolds, Subbroto Kumar Saha, Arjun Stokes, Chengji J. Zhou

Dis Model Mech. 2022 Jun 1; 15(6): dmm049517. Published online 2022 Jun 10. doi: 10.1242/dmm.049517

PMCID:: PMC9194482

Abstract Article

Select item 917902912.

Increased TBX6 Gene Dosages Induce Congenital Cervical Vertebral Malformations in Humans and Mice

Xiaojun Ren, Nan Yang, Nan Wu, Ximing Xu, Weisheng Chen, Ling Zhang, Yingping Li, Renqian Du, Shuangshuang Dong, Sen Zhao, Shuxia Chen, Li-Ping Jiang, Lianlei Wang, Jianguo Zhang, Zhihong Wu, Li Jin, Guixing Qiu, James R. Lupski, Jiangang Shi, Feng Zhang, Pengfei Liu

J Med Genet. Author manuscript; available in PMC 2022 Jun 9.

Published in final edited form as: J Med Genet. 2020 Jun; 57(6): 371–379. Published online 2019 Dec 30. doi: 10.1136/jmedgenet-2019-106333

PMCID:: PMC9179029

Abstract Article PDF–559K

Select item 839053013.

A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm

Luca Mariani, Xiaogang Guo, Niels Alvaro Menezes, Anna Maria Drozd, Selgin Deniz Çakal, Qinhu Wang, Elisabetta Ferretti

Nat Commun. 2021; 12: 5136. Published online 2021 Aug 26. doi: 10.1038/s41467-021-25370-4

PMCID:: PMC8390530

Abstract Article PDF–13M

Select item 771790414.

Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function

Matthew J Anderson, Valentin Magidson, Ryoichiro Kageyama, Mark Lewandoski

eLife. 2020; 9: e55608. Published online 2020 Nov 19. doi: 10.7554/eLife.55608

PMCID:: PMC7717904

Abstract Article PDF–6.9M

Select item 747363915.

Functionally distinct roles for T and Tbx6 during mouse development

Amy K. Wehn, Deborah R. Farkas, Carly E. Sedlock, Dibya Subedi, Deborah L. Chapman

Biol Open. 2020 Aug 15; 9(8): bio054692. Published online 2020 Aug 27. doi: 10.1242/bio.054692

PMCID:: PMC7473639

Abstract Article PDF–1.6M

Select item 739196216.

A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation

Alexander Aulehla, Winfried Wiegraebe, Valerie Baubet, Matthias B. Wahl, Chuxia Deng, Makoto Taketo, Mark Lewandoski, Olivier Pourquié

Nat Cell Biol. Author manuscript; available in PMC 2020 Jul 30.

Published in final edited form as: Nat Cell Biol. 2008 Feb; 10(2): 186–193. Published online 2007 Dec 23. doi: 10.1038/ncb1679

PMCID:: PMC7391962

Abstract Article PDF–1.6M

Select item 735493217.

Hedgehog–FGF signaling axis patterns anterior mesoderm during gastrulation

Alexander Guzzetta, Mervenaz Koska, Megan Rowton, Kaelan R. Sullivan, Jessica Jacobs-Li, Junghun Kweon, Hunter Hidalgo, Heather Eckart, Andrew D. Hoffmann, Rebecca Back, Stephanie Lozano, Anne M. Moon, Anindita Basu, Michael Bressan, Sebastian Pott, Ivan P. Moskowitz

Proc Natl Acad Sci U S A. 2020 Jul 7; 117(27): 15712–15723. Published online 2020 Jun 19. doi: 10.1073/pnas.1914167117

PMCID:: PMC7354932

Abstract Article PDF–3.0M

Select item 732415918.

A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation

André Dias, Anastasiia Lozovska, Filip J Wymeersch, Ana Nóvoa, Anahi Binagui-Casas, Daniel Sobral, Gabriel G Martins, Valerie Wilson, Moises Mallo

eLife. 2020; 9: e56615. Published online 2020 Jun 29. doi: 10.7554/eLife.56615

PMCID:: PMC7324159

Abstract Article PDF–16M

Select item 717484319.

A dorsal-ventral gradient of Wnt3a/β-catenin signals controls mouse hindgut extension and colon formation

Robert J. Garriock, Ravindra B. Chalamalasetty, JianJian Zhu, Mark W. Kennedy, Amit Kumar, Susan Mackem, Terry P. Yamaguchi

Development. 2020 Apr 15; 147(8): dev185108. Published online 2020 Apr 12. doi: 10.1242/dev.185108

PMCID:: PMC7174843

Abstract Article

Select item 711638920.

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse

Sebastian J. Arnold, Ulf K. Hofmann, Elizabeth K. Bikoff, Elizabeth J. Robertson

Development. Author manuscript; available in PMC 2020 Nov 18.

Published in final edited form as: Development. 2008 Feb 1; 135(3): 501–11. Published online 2008 Jan 2. doi: 10.1242/dev.014357

PMCID:: PMC7116389

Abstract Article PDF–2.8M

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