PMC Links for GEO Profiles (Select 81229413) - PMC

Links from GEO Profiles

Items: 1 to 20 of 31

<< First< Prev

Page of 2

Next >Last >>

Select item 92653441.

Mitoribosomal Deregulation Drives Senescence via TPP1-Mediated Telomere Deprotection

Seongki Min, So Mee Kwon, Jiwon Hong, Young-Kyoung Lee, Tae Jun Park, Su Bin Lim, Gyesoon Yoon

Cells. 2022 Jul; 11(13): 2079. Published online 2022 Jun 30. doi: 10.3390/cells11132079

PMCID:: PMC9265344

Abstract Article PDF–6.4M

Select item 85482612.

Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline

Jacqueline V Graniel, Kamlesh Bisht, Ann Friedman, James White, Eric Perkey, Ashley Vanderbeck, Alina Moroz, Léolène J Carrington, Joshua D Brandstadter, Frederick Allen, Adrienne Niederriter Shami, Peedikayil Thomas, Aniela Crayton, Mariel Manzor, Anna Mychalowych, Jennifer Chase, Saher S Hammoud, Catherine E Keegan, Ivan Maillard, Jayakrishnan Nandakumar

Life Sci Alliance. 2022 Jan; 5(1): e202101208. Published online 2021 Oct 13. doi: 10.26508/lsa.202101208

PMCID:: PMC8548261

Abstract Article PDF–3.5M

Select item 84487353.

Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres

Peili Gu, Shuting Jia, Taylor Takasugi, Valerie M. Tesmer, Jayakrishnan Nandakumar, Yong Chen, Sandy Chang

Nat Commun. 2021; 12: 5514. Published online 2021 Sep 17. doi: 10.1038/s41467-021-25799-7

PMCID:: PMC8448735

Abstract Article PDF–8.7M

Select item 82623374.

TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis

Sherilyn Grill, Shilpa Padmanaban, Ann Friedman, Eric Perkey, Frederick Allen, Valerie M. Tesmer, Jennifer Chase, Rami Khoriaty, Catherine E. Keegan, Ivan Maillard, Jayakrishnan Nandakumar

JCI Insight. 2021 May 10; 6(9): e138059. Published online 2021 May 10. doi: 10.1172/jci.insight.138059

PMCID:: PMC8262337

Abstract Article PDF–2.7M

Select item 69596105.

ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity

Courtney A. Lovejoy, Kaori Takai, Michael S. Huh, David J. Picketts, Titia de Lange

PLoS Biol. 2020 Jan; 18(1): e3000594. Published online 2020 Jan 2. doi: 10.1371/journal.pbio.3000594

PMCID:: PMC6959610

Abstract Article PDF–5.0M

Select item 61861846.

High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype

Ceren Sucularli, Peedikayil Thomas, Hande Kocak, James S. White, Bridget C. O’Connor, Catherine E. Keegan

Gene. Author manuscript; available in PMC 2019 Dec 30.

Published in final edited form as: Gene. 2018 Dec 30; 679: 219–231. Published online 2018 Sep 4. doi: 10.1016/j.gene.2018.09.002

PMCID:: PMC6186184

Abstract Article PDF–2.5M

Select item 58153127.

The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action

Sherilyn Grill, Valerie M. Tesmer, Jayakrishnan Nandakumar

Cell Rep. Author manuscript; available in PMC 2018 Feb 16.

Published in final edited form as: Cell Rep. 2018 Jan 30; 22(5): 1132–1140. doi: 10.1016/j.celrep.2018.01.012

PMCID:: PMC5815312

Abstract Article PDF–1.3M

Select item 54251238.

The differential spatiotemporal expression pattern of shelterin genes throughout lifespan

Kay-Dietrich Wagner, Yilin Ying, Waiian Leong, Jie Jiang, Xuefei Hu, Yi Chen, Jean-François Michiels, Yiming Lu, Eric Gilson, Nicole Wagner, Jing Ye

Aging (Albany NY) 2017 Apr; 9(4): 1219–1228. Published online 2017 Apr 17. doi: 10.18632/aging.101223

PMCID:: PMC5425123

Abstract Article PDF–4.4M

Select item 52489669.

Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease

Tanveer Ahmad, Isaac K. Sundar, Ana M. Tormos, Chad A. Lerner, Janice Gerloff, Hongwei Yao, Irfan Rahman

Am J Respir Cell Mol Biol. 2017 Jan; 56(1): 38–49. doi: 10.1165/rcmb.2016-0198OC

PMCID:: PMC5248966

Abstract Article PDF–3.0M

Select item 472433710.

TPP1 blocks an ATR-mediated resection mechanism at telomeres

Tatsuya Kibe, Michal Zimmermann, Titia de Lange

Mol Cell. Author manuscript; available in PMC 2017 Jan 21.

Published in final edited form as: Mol Cell. 2016 Jan 21; 61(2): 236–246. Published online 2016 Jan 14. doi: 10.1016/j.molcel.2015.12.016

Correction in:: Mol Cell. 2017 Apr 20; 66(2): 300.

PMCID:: PMC4724337

Abstract Article PDF–2.1M

Select item 423324111.

TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling

Michal Zimmermann, Tatsuya Kibe, Shaheen Kabir, Titia de Lange

Genes Dev. 2014 Nov 15; 28(22): 2477–2491. doi: 10.1101/gad.251611.114

PMCID:: PMC4233241

Abstract Article PDF–1.6M

Select item 414884912.

Binding of TPP1 Protein to TIN2 Protein Is Required for POT1a,b Protein-mediated Telomere Protection

David Frescas, Titia de Lange

J Biol Chem. 2014 Aug 29; 289(35): 24180–24187. Published online 2014 Jul 23. doi: 10.1074/jbc.M114.592592

PMCID:: PMC4148849

Abstract Article PDF–2.5M

Select item 399356013.

TRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1

David Frescas, Titia de Lange

Mol Cell Biol. 2014 Apr; 34(7): 1349–1362. doi: 10.1128/MCB.01052-13

PMCID:: PMC3993560

Abstract Article PDF–5.2M

Select item 396765614.

Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation

Morgan Jones, Gail Osawa, Joshua A. Regal, Daniel N. Weinberg, James Taggart, Hande Kocak, Ann Friedman, David O. Ferguson, Catherine E. Keegan, Ivan Maillard

J Clin Invest. 2014 Jan 2; 124(1): 353–366. Published online 2013 Dec 9. doi: 10.1172/JCI67871

PMCID:: PMC3967656

Abstract Article PDF–2.5M

Select item 368073215.

HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

Dennis Kappei, Falk Butter, Christian Benda, Marion Scheibe, Irena Draškovič, Michelle Stevense, Clara Lopes Novo, Claire Basquin, Masatake Araki, Kimi Araki, Dragomir Blazhev Krastev, Ralf Kittler, Rolf Jessberger, J Arturo Londoño-Vallejo, Matthias Mann, Frank Buchholz

EMBO J. 2013 Jun 12; 32(12): 1681–1701. Published online 2013 May 17. doi: 10.1038/emboj.2013.105

PMCID:: PMC3680732

Abstract Article PDF–1.6M

Select item 363176016.

TPP1 Is Required for TERT Recruitment, Telomere Elongation during Nuclear Reprogramming, and Normal Skin Development in Mice

Agueda M. Tejera, Martina Stagno d’Alcontres, Maria Thanasoula, Rosa M. Marion, Paula Martinez, Chunyan Liao, Juana M. Flores, Madalena Tarsounas, Maria A. Blasco

Dev Cell. Author manuscript; available in PMC 2013 Apr 22.

Published in final edited form as: Dev Cell. 2010 May 18; 18(5): 775–789. doi: 10.1016/j.devcel.2010.03.011