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Select item 102297431.

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN

Kaini Zhang, Chen Yang, Xin Zhou, Jin Liang, Jianjin Guo, Min Li, Yi Zhang, Shulin Shao, Peng Sun, Kai Li, Jingjing Huang, Fang Chen, Xiubin Liang, Dongming Su

Cell Mol Life Sci. 2023 Jun; 80(6): 168. Published online 2023 May 30. doi: 10.1007/s00018-023-04820-w

PMCID:: PMC10229743

Abstract Article PDF–2.9M

Select item 101122812.

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1

François Le Guerroué, Eric N Bunker, William M Rosencrans, Jack T Nguyen, Mohammed A Basar, Achim Werner, Tsui-Fen Chou, Chunxin Wang, Richard J Youle

Mol Cell. Author manuscript; available in PMC 2024 Mar 16.

Published in final edited form as: Mol Cell. 2023 Mar 16; 83(6): 927–941.e8. Published online 2023 Mar 9. doi: 10.1016/j.molcel.2023.02.023

PMCID:: PMC10112281

Abstract Article PDF–2.4M

Select item 99745093.

ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression

Tzu-Po Chuang, Wei-Yun Lai, Jonatan L. Gabre, Dan E. Lind, Ganesh Umapathy, Abdulmalik A. Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B. Thorén, Anh Le, Robert C. Doebele, Jimmy Van den Eynden, Ruth H. Palmer, Bengt Hallberg

Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2216479120. Published online 2023 Feb 15. doi: 10.1073/pnas.2216479120

PMCID:: PMC9974509

Abstract Article PDF–2.6M

Select item 97419674.

DDX24 promotes metastasis by regulating RPL5 in non‐small cell lung cancer

Xinyan Hu, Fangfang Li, Yulan Zhou, Hairun Gan, Tiancheng Wang, Luting Li, Haoyu Long, Bing Li, Pengfei Pang

Cancer Med. 2022 Dec; 11(23): 4513–4525. Published online 2022 Jul 21. doi: 10.1002/cam4.4835

PMCID:: PMC9741967

Abstract Article PDF–25M

Select item 86538065.

Evaluation of squamous cell carcinoma antigen 1 expression in oral squamous cell carcinoma (tumor cells and peritumoral T-lymphocytes) and verrucous carcinoma and comparison with normal oral mucosa

Samira Derakhshan, Arvin Poosti, Amirnader Emami Razavi, Mohammad Amin Moosavi, Nazanin Mahdavi, Fereshteh Baghaei Naieni, Kambiz Kamyab Hesari, Amirsina Rahpeima

J Appl Oral Sci. 2021; 29: e20210374. Published online 2021 Dec 1. doi: 10.1590/1678-7757-2021-0374

PMCID:: PMC8653806

Abstract Article PDF–8.5M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76593777.

Prognostic value of human papillomavirus and squamous cell carcinoma antigen in head and neck squamous cell carcinoma

Zeyi Deng, Masahiro Hasegawa, Yukashi Yamashita, Sen Matayoshi, Asanori Kiyuna, Shinya Agena, Takayuki Uehara, Hiroyuki Maeda, Mikio Suzuki

Cancer Sci. 2012 Dec; 103(12): 2127–2134. Published online 2012 Oct 17. doi: 10.1111/cas.12009

PMCID:: PMC7659377

Abstract Article PDF–508K

Select item 75668818.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 74273279.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 701834210.

Clinical significance of progastrin-releasing peptide, neuron-specific enolase, chromogranin a, and squamous cell cancer antigen in pulmonary neuroendocrine tumors

Nuri TUTAR, Nur Aleyna YETKİN, Cevat YAZICI, Ömer ÖNAL, Olgun KONTAŞ, Fahrettin KELEŞTEMUR

Turk J Med Sci. 2019; 49(3): 774–781. Published online 2019 Jun 18. doi: 10.3906/sag-1810-147

PMCID:: PMC7018342

Abstract Article PDF–921K

Select item 673589211.

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

David Pladevall-Morera, Stephanie Munk, Andreas Ingham, Lorenza Garribba, Eliene Albers, Ying Liu, Jesper V Olsen, Andres J Lopez-Contreras

Nucleic Acids Res. 2019 Sep 5; 47(15): 8004–8018. Published online 2019 Jun 10. doi: 10.1093/nar/gkz510

Correction in:: Nucleic Acids Res. 2019 Sep 5; 47(15): 8332.

PMCID:: PMC6735892

Abstract Article PDF–5.4M

Select item 670963512.

Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6

Brianna E. Talbot, David H. Vandorpe, Brian R. Stotter, Seth L. Alper, Johannes S. Schlondorff

J Biol Chem. 2019 Aug 23; 294(34): 12655–12669. Published online 2019 Jul 2. doi: 10.1074/jbc.RA119.008299

PMCID:: PMC6709635

Abstract Article PDF–2.5M

Select item 655243213.

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression

Jung-Sik Kim, Xiaoyuan He, Jie Liu, Zhijun Duan, Taeyeon Kim, Julia Gerard, Brian Kim, Manoj M. Pillai, William S. Lane, William S. Noble, Bogdan Budnik, Todd Waldman

J Biol Chem. 2019 May 31; 294(22): 8760–8772. Published online 2019 Apr 22. doi: 10.1074/jbc.RA119.007832

PMCID:: PMC6552432

Abstract Article PDF–3.5M

Select item 650102414.

Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity

Cristian Turato, Melania Scarpa, Andromachi Kotsafti, Andrea Cappon, Santina Quarta, Alessandra Biasiolo, Francesco Cavallin, Elisabetta Trevellin, Vincenza Guzzardo, Matteo Fassan, Vanna Chiarion‐Sileni, Carlo Castoro, Massimo Rugge, Roberto Vettor, Marco Scarpa, Patrizia Pontisso

Cancer Sci. 2019 May; 110(5): 1552–1563. Published online 2019 Apr 15. doi: 10.1111/cas.13986

PMCID:: PMC6501024

Abstract Article PDF–1.2M

Select item 644057715.

Isoform-specific GSK3A activity is negatively correlated with human sperm motility

M J Freitas, J V Silva, C Brothag, B Regadas-Correia, M Fardilha, S Vijayaraghavan

Mol Hum Reprod. 2019 Apr; 25(4): 171–183. Published online 2019 Mar 2. doi: 10.1093/molehr/gaz009

PMCID:: PMC6440577

Abstract Article PDF–1.0M

Select item 642409816.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 629825417.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 592080018.

Anti-apoptotic Serine Protease Inhibitors contribute towards the survival of allergenic Th2 cells

Mohamed H. Shamji, Jeff N. Temblay, Wei Cheng, Susan M. Byrne, Ellen Macfarlane, Amy R. Switzer, Natalia DC Francisco, Fedina Olexandra, Fabian Jacubczik, Stephen R. Durham, Philip G. Ashton-Rickardt

J Allergy Clin Immunol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Allergy Clin Immunol. 2018 Aug; 142(2): 569–581.e5. Published online 2017 Oct 26. doi: 10.1016/j.jaci.2017.07.055

PMCID:: PMC5920800

Abstract Article PDF–1.0M

Select item 589141719.

Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function

Jan B Heidelberger, Andrea Voigt, Marina E Borisova, Giuseppe Petrosino, Stefanie Ruf, Sebastian A Wagner, Petra Beli

EMBO Rep. 2018 Apr; 19(4): e44754. Published online 2018 Feb 21. doi: 10.15252/embr.201744754

PMCID:: PMC5891417

Abstract Article PDF–1.0M

Select item 583915820.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

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