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Items: 1 to 20 of 79

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder
Ami Oguro, Taichi Fujiyama, Yasuhiro Ishihara, Chisato Kataoka, Megumi Yamamoto, Komyo Eto, Yoshihiro Komohara, Susumu Imaoka, Toshihide Sakuragi, Mayumi Tsuji, Eiji Shibata, Yaichiro Kotake, Takeshi Yamazaki
J Lipid Res. 2023 Nov; 64(11): 100458. Published online 2023 Oct 12. doi: 10.1016/j.jlr.2023.100458
PMCID:
PMC10656226
AbstractArticlePDF–2.6M
3.
USP14 governs CYP2E1 to promote nonalcoholic fatty liver disease through deubiquitination and stabilization of HSP90AA1
Dongqin Wei, Xin Tian, Longbo Zhu, Han Wang, Chao Sun
Cell Death Dis. 2023 Aug; 14(8): 566. Published online 2023 Aug 26. doi: 10.1038/s41419-023-06091-6
PMCID:
PMC10460448
AbstractArticlePDF–15M
4.
脂质纳米粒递送靶向Cyp2e1基因的小干扰RNA可减轻小鼠亚急性酒精性肝损伤
吴 爽, 陈 秋冰, 王 亚兰, 殷 昊, 魏 渊
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023 Jun 25; 52(3): 306–317. Chinese. doi: 10.3724/zdxbyxb-2022-0729
PMCID:
PMC10409911
AbstractArticlePDF–5.1M
5.
Chronotoxicity of Acrylamide in Mice Fed a High-Fat Diet: The Involvement of Liver CYP2E1 Upregulation and Gut Leakage
Luanfeng Wang, Yanhong Liu, Huajing Gao, Shuqi Ge, Xinru Yao, Chang Liu, Xintong Tan
Molecules. 2023 Jul; 28(13): 5132. Published online 2023 Jun 30. doi: 10.3390/molecules28135132
PMCID:
PMC10343525
AbstractArticlePDF–3.2M
6.
Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Myung-Ho Kim, Giljae Lee, Hyun Ju You, Won-Mook Choi, Keungmo Yang, Tom Ryu, Kyurae Kim, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Hyuk Soo Eun, Seok-Hwan Kim, GwangPyo Ko, Jong-Eun Park, Bin Gao, Won Kim, Won-Il Jeong
Exp Mol Med. 2023 Jan; 55(1): 158–170. Published online 2023 Jan 11. doi: 10.1038/s12276-022-00921-x
PMCID:
PMC9898237
AbstractArticlePDF–8.9M
7.
Alcohol induced hepatic retinoid depletion is associated with the induction of multiple retinoid catabolizing cytochrome P450 enzymes
Afroza Ferdouse, Rishi R. Agrawal, Madeleine A. Gao, Hongfeng Jiang, William S. Blaner, Robin D. Clugston
PLoS One. 2022; 17(1): e0261675. Published online 2022 Jan 14. doi: 10.1371/journal.pone.0261675
PMCID:
PMC8759667
AbstractArticlePDF–1.6M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1
Wenhao Ge, Tao Wang, Yang Zhao, Yunxia Yang, Qi Sun, Xiao Yang, Yan Gao, Xi Xu, Jianfa Zhang
Cell Death Dis. 2021 Jan; 12(1): 76. Published online 2021 Jan 12. doi: 10.1038/s41419-020-03343-7
PMCID:
PMC7804260
AbstractArticlePDF–7.6M
10.
Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells
Olivia Matthews, Emma E. Morrison, John D. Tranter, Philip Starkey Lewis, Iqbal S. Toor, Abhishek Srivastava, Rebecca Sargeant, Helen Rollison, Kylie P. Matchett, Timothy J. Kendall, Gillian A. Gray, Chris Goldring, Kevin Park, Laura Denby, Neeraj Dhaun, Matthew A. Bailey, Neil C. Henderson, Dominic Williams, James W. Dear
EBioMedicine. 2020 Dec; 62: 103092. Published online 2020 Nov 21. doi: 10.1016/j.ebiom.2020.103092
PMCID:
PMC7689533
AbstractArticlePDF–2.0M
11.
DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver
Mohamad M. Kronfol, Fay M. Jahr, Mikhail G. Dozmorov, Palak S. Phansalkar, Lin Y. Xie, Karolina A. Aberg, MaryPeace McRae, Elvin T. Price, Patricia W. Slattum, Philip M. Gerk, Joseph L. McClay
GeroScience. 2020 Jun; 42(3): 819–832. Published online 2020 Mar 27. doi: 10.1007/s11357-020-00181-5
PMCID:
PMC7287002
AbstractArticlePDF–1.0M
12.
Methionine Adenosyltransferase α1 is targeted to the mitochondrial matrix and interacts with cytochrome P450 2E1 to lower its expression
Ben Murray, Hui Peng, Lucia Barbier-Torres, Aaron Robinson, Tony W. H. Li, Wei Fan, Maria Lauda Tomasi, Roberta A. Gottlieb, Jenny Van Eyk, Zhimin Lu, ML Martínez-Chantar, Suthat Liangpunsakul, Nicholas J Skill, José M. Mato, Shelly C. Lu
Hepatology. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Hepatology. 2019 Dec; 70(6): 2018–2034. Published online 2019 Jun 25. doi: 10.1002/hep.30762
PMCID:
PMC6842664
AbstractArticlePDF–2.4M
13.
Glutamate/metabotropic glutamate receptor-5 signaling in hepatic stellate cells drives endocannabinoid-mediated alcoholic steatosis
Won-Mook Choi, Hee-Hoon Kim, Myung-Ho Kim, Resat Cinar, Hyon-Seung Yi, Hyuk Soo Eun, Seok-Hwan Kim, Young Jae Choi, Young-Sun Lee, So Yeon Kim, Wonhyo Seo, Jun-Hee Lee, Young-Ri Shim, Ye Eun Kim, Keungmo Yang, Tom Ryu, Jung Hwan Hwang, Chul-Ho Lee, Hueng-Sik Choi, Bin Gao, Won Kim, Sang Kyum Kim, George Kunos, Won-Il Jeong
Cell Metab. Author manuscript; available in PMC 2020 Nov 5.
Published in final edited form as: Cell Metab. 2019 Nov 5; 30(5): 877–889.e7. Published online 2019 Aug 29. doi: 10.1016/j.cmet.2019.08.001
PMCID:
PMC6834910
AbstractArticlePDF–2.0M
14.
Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1
Liping Chen, Ping Guo, Haiyan Zhang, Wenxue Li, Chen Gao, Zhenlie Huang, Junling Fan, Yuling Zhang, Xue Li, Xiaoling Liu, Fangping Wang, Shan Wang, Qingye Li, Zhini He, Huiyao Li, Shen Chen, Xiaonen Wu, Lizhu Ye, Qiong Li, Huanwen Tang, Qing Wang, Guanghui Dong, Yongmei Xiao, Wen Chen, Daochuan Li
J Biol Chem. 2019 Feb 15; 294(7): 2486–2499. Published online 2018 Dec 19. doi: 10.1074/jbc.RA118.006319
PMCID:
PMC6378973
AbstractArticlePDF–3.4M
15.
Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
Yuga Teranishi, Tsutomu Matsubara, Kristopher W Krausz, Thi TT Le, Frank J Gonzalez, Katsutoshi Yoshizato, Kazuo Ikeda, Norifumi Kawada
Lab Invest. Author manuscript; available in PMC 2019 Jan 14.
Published in final edited form as: Lab Invest. 2015 May; 95(5): 515–524. Published online 2015 Feb 16. doi: 10.1038/labinvest.2015.29
PMCID:
PMC6331008
AbstractArticlePDF–969K
16.
Cytochrome P450 2E1 is responsible for the initiation of 1,2-dichloropropane-induced liver damage
Yukie Yanagiba, Tetsuya Suzuki, Megumi Suda, Rieko Hojo, Frank J Gonzalez, Tamie Nakajima, Rui-Sheng Wang
Toxicol Ind Health. Author manuscript; available in PMC 2018 Dec 20.
Published in final edited form as: Toxicol Ind Health. 2016 Sep; 32(9): 1589–1597. Published online 2015 Feb 13. doi: 10.1177/0748233714568801
PMCID:
PMC6300984
AbstractArticlePDF–698K
17.
TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity
Ratanesh K. Seth, Suvarthi Das, Diptadip Dattaroy, Varun Chandrashekaran, Firas Alhasson, Gregory Michelotti, Mitzi Nagarkatti, Prakash Nagarkatti, Anna Mae Diehl, P. Darwin Bell, Wolfgang Liedtke, Saurabh Chatterjee
Free Radic Biol Med. Author manuscript; available in PMC 2018 Jun 6.
Published in final edited form as: Free Radic Biol Med. 2017 Jan; 102: 260–273. Published online 2016 Nov 29. doi: 10.1016/j.freeradbiomed.2016.11.047
PMCID:
PMC5989309
AbstractArticlePDF–1.8M
18.
SUMOylation regulates cytochrome P450 2E1 expression and activity in alcoholic liver disease
Maria Lauda Tomasi, Komal Ramani, Minjung Ryoo, Carla Cossu, Andrea Floris, Ben J. Murray, Ainhoa Iglesias-Ara, Ylenia Spissu, Nirmala Mavila
FASEB J. 2018 Jun; 32(6): 3278–3288. Published online 2018 Jan 18. doi: 10.1096/fj.201701124R
PMCID:
PMC5956242
AbstractArticle
19.
Hepatic and hippocampal Cyp enzymes over-expression during spontaneous recurrent seizures
Leonie Runtz, Benoit Girard, Marion Toussenot, Julie Espallergues, Alexis Fayd’Herbe De Maudave, Alexandre Milman, Frederic deBock, Chaitali Ghosh, Nathalie C. Guérineau, Jean-Marc Pascussi, Federica Bertaso, Nicola Marchi
Epilepsia. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Epilepsia. 2018 Jan; 59(1): 123–134. Published online 2017 Nov 10. doi: 10.1111/epi.13942
PMCID:
PMC5774654
AbstractArticlePDF–2.6M
20.
2,3,4′,5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2
Shangfu Xu, Jie Liu, Jingshan Shi, Zhengtao Wang, Lili Ji
Sci Rep. 2017; 7: 16511. Published online 2017 Nov 28. doi: 10.1038/s41598-017-16688-5
PMCID:
PMC5705655
AbstractArticlePDF–8.6M

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