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Select item 111892971.

Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversification

Meng Zhu, Maciej Meglicki, Adiyant Lamba, Peizhe Wang, Christophe Royer, Karen Turner, Muhammad Abdullah Jauhar, Celine Jones, Tim Child, Kevin Coward, Jie Na, Magdalena Zernicka-Goetz

Nat Struct Mol Biol. 2024; 31(6): 964–976. Published online 2024 May 24. doi: 10.1038/s41594-024-01311-9

PMCID:: PMC11189297

Abstract Article PDF–6.5M

Select item 110463002.

The tumor suppressor NF2 modulates TEAD4 stability and activity in Hippo signaling via direct interaction

Mengying Wu, Liqiao Hu, Lingli He, Liang Yuan, Lingling Yang, Bin Zhao, Lei Zhang, Xiaojing He

J Biol Chem. 2024 May; 300(5): 107212. Published online 2024 Mar 24. doi: 10.1016/j.jbc.2024.107212

PMCID:: PMC11046300

Abstract Article PDF–2.1M

Select item 108886843.

Integrative Epigenetic and Molecular Analysis Reveals a Novel Promoter for a New Isoform of the Transcription Factor TEAD4

Shima Rashidiani, Gizaw Mamo, Benjámin Farkas, András Szabadi, Bálint Farkas, Veronika Uszkai, András Császár, Barbara Brandt, Kálmán Kovács, Marianna Pap, Tibor A. Rauch

Int J Mol Sci. 2024 Feb; 25(4): 2223. Published online 2024 Feb 13. doi: 10.3390/ijms25042223

PMCID:: PMC10888684

Abstract Article PDF–3.2M

Select item 107947104.

VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification

Yueli Yang, Wenqi Jia, Zhiwei Luo, Yunpan Li, Hao Liu, Lixin Fu, Jinxiu Li, Yu Jiang, Junjian Lai, Haiwei Li, Babangida Jabir Saeed, Yi Zou, Yuan Lv, Liang Wu, Ting Zhou, Yongli Shan, Chuanyu Liu, Yiwei Lai, Longqi Liu, Andrew P. Hutchins, Miguel A. Esteban, Md. Abdul Mazid, Wenjuan Li

Nat Commun. 2024; 15: 583. Published online 2024 Jan 17. doi: 10.1038/s41467-024-44780-8

PMCID:: PMC10794710

Abstract Article PDF–3.4M

Select item 104461405.

Tea domain transcription factor TEAD4 mitigates TGF-β signaling and hepatocellular carcinoma progression independently of YAP

Weicheng Luo, Yi Li, Yi Zeng, Yining Li, Minzhang Cheng, Cheng Zhang, Fei Li, Yiqing Wu, Chunhong Huang, Xiaolong Yang, Joachim Kremerskothen, Jianmin Zhang, Chunbo Zhang, Shuo Tu, Zhihua Li, Zhijun Luo, Zhenghong Lin, Xiaohua Yan

J Mol Cell Biol. 2023 Feb; 15(2): mjad010. Published online 2023 Feb 20. doi: 10.1093/jmcb/mjad010

PMCID:: PMC10446140

Abstract Article PDF–1.8M

Select item 101580316.

Bulk and single-cell transcriptome profiling reveal extracellular matrix mechanical regulation of lipid metabolism reprograming through YAP/TEAD4/ACADL axis in hepatocellular carcinoma

Jingwei Cai, Tianyi Chen, Zhiyu Jiang, Jiafei Yan, Zhengtao Ye, Yeling Ruan, Liye Tao, Zefeng Shen, Xiao Liang, Yifan Wang, Junjie Xu, Xiujun Cai

Int J Biol Sci. 2023; 19(7): 2114–2131. Published online 2023 Apr 9. doi: 10.7150/ijbs.82177

PMCID:: PMC10158031

Abstract Article PDF–11M

Select item 101249077.

The YAP–TEAD4 complex promotes tumor lymphangiogenesis by transcriptionally upregulating CCBE1 in colorectal cancer

Jinglue Song, Xuening Dang, Xia Shen, Yun Liu, Jiani Gu, Xiang Peng, Zhenyu Huang, Wanjin Hong, Long Cui, Chen-Ying Liu

J Biol Chem. 2023 Apr; 299(4): 103012. Published online 2023 Feb 11. doi: 10.1016/j.jbc.2023.103012

PMCID:: PMC10124907

Abstract Article PDF–5.4M

Select item 94112028.

CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis

Yuegui Guo, Zhehui Zhu, Zhenyu Huang, Long Cui, Wei Yu, Wanjin Hong, Zhaocai Zhou, Peng Du, Chen-Ying Liu

Nat Commun. 2022; 13: 4995. Published online 2022 Aug 25. doi: 10.1038/s41467-022-32674-6

PMCID:: PMC9411202

Abstract Article PDF–9.8M

Select item 93561349.

The deubiquitinase USP7 promotes HNSCC progression via deubiquitinating and stabilizing TAZ

Jin Li, Yibin Dai, Han Ge, Songsong Guo, Wei Zhang, Yanling Wang, Laikui Liu, Jie Cheng, Hongbing Jiang

Cell Death Dis. 2022 Aug; 13(8): 677. Published online 2022 Aug 5. doi: 10.1038/s41419-022-05113-z

PMCID:: PMC9356134

Abstract Article PDF–6.1M

Select item 883779210.

YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription

Xiangfei Xue, Xiaoting Tian, Congcong Zhang, Yayou Miao, Yikun Wang, Yingxiu Peng, Shiyu Qiu, Hong Wang, Jiangtao Cui, Leiqun Cao, Fenyong Sun, Yongxia Qiao, Xiao Zhang

Cell Death Discov. 2022; 8: 59. Published online 2022 Feb 11. doi: 10.1038/s41420-022-00842-8

PMCID:: PMC8837792

Abstract Article PDF–5.7M

Select item 880634811.

The interaction of TEA domain transcription factor 4 (TEAD4) and Yes-associated protein 1 (YAP1) promoted the malignant process mediated by serum/glucocorticoid regulated kinase 1 (SGK1)

Songlin He, Hanlu Zhang, Zongwei Xiao, Sandeep Bhushan, Ke Gao, Wenping Wang

Bioengineered. 2021; 12(1): 601–614. Published online 2021 Feb 10. doi: 10.1080/21655979.2021.1882142

PMCID:: PMC8806348

Abstract Article PDF–7.0M

Select item 838303412.

HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway

Hui Geng, Guangli Liu, Jiandong Hu, Jianchao Li, Dong Wang, Shenshan Zou, Xintao Xu

Mol Med Rep. 2021 Oct; 24(4): 722. Published online 2021 Aug 11. doi: 10.3892/mmr.2021.12361

PMCID:: PMC8383034

Abstract Article PDF–15M

Select item 837640713.

Biochemical properties of VGLL4 from Homo sapiens and Tgi from Drosophila melanogaster and possible biological implications

Yannick Mesrouze, Marco Meyerhofer, Catherine Zimmermann, Patrizia Fontana, Dirk Erdmann, Patrick Chène

Protein Sci. 2021 Sep; 30(9): 1871–1881. Published online 2021 Jun 8. doi: 10.1002/pro.4138

PMCID:: PMC8376407

Abstract Article PDF–2.3M

Select item 836644714.

NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop

Bowen Hu, Shijie Zhou, Xuefeng Hu, Hua Zhang, Xiaorong Lan, Mei Li, Yunbing Wang, Qinsheng Hu

J Cell Mol Med. 2021 Jul; 25(13): 5976–5987. Published online 2021 May 16. doi: 10.1111/jcmm.16409

PMCID:: PMC8366447

Abstract Article PDF–2.3M

Select item 827306215.

RTEF-1 Inhibits Vascular Smooth Muscle Cell Calcification through Regulating Wnt/β-Catenin Signaling Pathway

Jingjing Cong, Bei Cheng, Jinyu Liu, Ping He

Calcif Tissue Int. 2021; 109(2): 203–214. Published online 2021 Mar 13. doi: 10.1007/s00223-021-00833-4

PMCID:: PMC8273062

Abstract Article PDF–1.5M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 794850917.

MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway

Jinqiu Lu, Zonghao Hu, Yujie Deng, Qingzhe Wu, Ming Wu, Hai Song

J Biol Chem. 2021 Jan-Jun; 296: 100400. Published online 2021 Feb 9. doi: 10.1016/j.jbc.2021.100400

PMCID:: PMC7948509

Abstract Article PDF–3.9M

Select item 788758018.

RNF219/α‐Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications

Shuxia Zhang, Yingru Xu, Chan Xie, Liangliang Ren, Geyan Wu, Meisongzhu Yang, Xingui Wu, Miaoling Tang, Yameng Hu, Ziwen Li, Ruyuan Yu, Xinyi Liao, Shuang Mo, Jueheng Wu, Mengfeng Li, Erwei Song, Yanfei Qi, Libing Song, Jun Li

Adv Sci (Weinh) 2021 Feb; 8(4): 2001961. Published online 2020 Dec 31. doi: 10.1002/advs.202001961

Correction in:: Adv Sci (Weinh). 2021 Aug; 8(16): 2102956.

PMCID:: PMC7887580

Abstract Article PDF–9.3M

Select item 768969319.

TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics

Verena B. K. Kunig, Dr. Marco Potowski, Dr. Mohammad Akbarzadeh, Dr. Mateja Klika Škopić, Denise dos Santos Smith, Lukas Arendt, Ina Dormuth, Dr. Hélène Adihou, Blaž Andlovic, Dr. Hacer Karatas, Shabnam Shaabani, Tryfon Zarganes‐Tzitzikas, Prof. Dr. Constantinos G. Neochoritis, Ran Zhang, Prof. Dr. Matthew Groves, Dr. Stéphanie M. Guéret, Dr. Christian Ottmann, Prof. Dr. Jörg Rahnenführer, Prof. Dr. Roland Fried, Prof. Dr. Alexander Dömling, Dr. Andreas Brunschweiger

Angew Chem Int Ed Engl. 2020 Nov 9; 59(46): 20338–20342. Published online 2020 Jul 15. doi: 10.1002/anie.202006280

PMCID:: PMC7689693

Abstract Article PDF–2.5M

Select item 729072120.

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux

Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070

PMCID:: PMC7290721

Abstract Article PDF–9.2M

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