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Items: 17

1.
Delivery of CDNF by AAV-mediated gene transfer protects dopamine neurons and regulates ER stress and inflammation in an acute MPTP mouse model of Parkinson’s disease
Jinhan Nam, Christopher T. Richie, Brandon K. Harvey, Merja H. Voutilainen
Sci Rep. 2024; 14: 16487. Published online 2024 Jul 17. doi: 10.1038/s41598-024-65735-5
PMCID:
PMC11254911
AbstractArticlePDF–8.4M
2.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
3.
Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs
Julia Konovalova, Dmytro Gerasymchuk, Sergio Navarette Arroyo, Sven Kluske, Francesca Mastroianni, Alba Vargas Pereyra, Andrii Domanskyi
Int J Mol Sci. 2021 Sep; 22(18): 9691. Published online 2021 Sep 7. doi: 10.3390/ijms22189691
PMCID:
PMC8466963
AbstractArticlePDF–2.7M
4.
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo
Katrina Albert, Diana P. Raymundo, Anne Panhelainen, Ave Eesmaa, Liana Shvachiy, Gabriela R. Araújo, Piotr Chmielarz, Xu Yan, Aastha Singh, Yraima Cordeiro, Fernando L. Palhano, Debora Foguel, Kelvin C. Luk, Andrii Domanskyi, Merja H. Voutilainen, Henri J. Huttunen, Tiago F. Outeiro, Mart Saarma, Marcius S. Almeida, Mikko Airavaara
Mol Ther. 2021 Sep 1; 29(9): 2821–2840. Published online 2021 May 1. doi: 10.1016/j.ymthe.2021.04.035
PMCID:
PMC8417450
AbstractArticlePDF–3.2M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Protection of dopamine neurons by CDNF and neurturin variant N4 against MPP+ in dissociated cultures from rat mesencephalon
Juliann D. Jaumotte, Mart Saarma, Michael J. Zigmond
PLoS One. 2021; 16(2): e0245663. Published online 2021 Feb 3. doi: 10.1371/journal.pone.0245663
PMCID:
PMC7857574
AbstractArticlePDF–1.9M
7.
Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population
Yongfeng Yang, Hongyan Yu, Wenqiang Li, Bing Liu, Hongxing Zhang, Shuang Ding, Yanli Lu, Tianzi Jiang, Luxian Lv
Behav Brain Funct. 2018; 14: 1. Published online 2018 Jan 3. doi: 10.1186/s12993-017-0133-4
PMCID:
PMC5753570
AbstractArticlePDF–778K
8.
Cerebral Dopamine Neurotrophic Factor: A Potential Therapeutic Agent for Parkinson’s Disease
Tingting Tang, Yong Li, Qian Jiao, Xixun Du, Hong Jiang
Neurosci Bull. 2017 Oct; 33(5): 568–575. Published online 2017 Mar 23. doi: 10.1007/s12264-017-0123-4
PMCID:
PMC5636730
AbstractArticlePDF–510K
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Therapeutic efficacy of AAV8-mediated intrastriatal delivery of human cerebral dopamine neurotrophic factor in 6-OHDA-induced parkinsonian rat models with different disease progression
Lizheng Wang, Zixuan Wang, Rui Zhu, Jinpeng Bi, Xinyao Feng, Wenmo Liu, Jiaxin Wu, Haihong Zhang, Hui Wu, Wei Kong, Bin Yu, Xianghui Yu
PLoS One. 2017; 12(6): e0179476. Published online 2017 Jun 16. doi: 10.1371/journal.pone.0179476
PMCID:
PMC5473573
AbstractArticlePDF–6.8M
11.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
12.
The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers
Cristiane Latge, Katia M. S. Cabral, Guilherme A. P. de Oliveira, Diana P. Raymundo, Julia A. Freitas, Laizes Johanson, Luciana F. Romão, Fernando L. Palhano, Torsten Herrmann, Marcius S. Almeida, Debora Foguel
J Biol Chem. 2015 Aug 14; 290(33): 20527–20540. Published online 2015 Jul 6. doi: 10.1074/jbc.M115.662254
PMCID:
PMC4536457
AbstractArticlePDF–3.7M
13.
Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra
Rasajna Nadella, Merja H Voutilainen, Mart Saarma, Juan A Gonzalez-Barrios, Bertha A Leon-Chavez, Judith M Dueñas Jiménez, Sergio H Dueñas Jiménez, Lourdes Escobedo, Daniel Martinez-Fong
J Neuroinflammation. 2014; 11: 209. Published online 2014 Dec 16. doi: 10.1186/s12974-014-0209-0
PMCID:
PMC4275959
AbstractArticlePDF–3.2M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Association analysis between polymorphisms in the conserved dopamine neurotrophic factor (CDNF) gene and cocaine dependence
Falk W. Lohoff, Paul J. Bloch, Thomas N. Ferraro, Wade H. Berrettini, Helen M. Pettinati, Charles A. Dackis, Charles P. O’Brien, Kyle M. Kampman, David W. Oslin
Neurosci Lett. Author manuscript; available in PMC 2010 Apr 10.
Published in final edited form as: Neurosci Lett. 2009 Apr 10; 453(3): 199–203. Published online 2009 Feb 21. doi: 10.1016/j.neulet.2009.02.026
PMCID:
PMC2680755
AbstractArticlePDF–499K
16.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K
17.
Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver
Xiang-Ru Xu, Jian Huang, Zhi-Gang Xu, Bin-Zhi Qian, Zhi-Dong Zhu, Qing Yan, Ting Cai, Xin Zhang, Hua-Sheng Xiao, Jian Qu, Feng Liu, Qiu-Hua Huang, Zhi-Hong Cheng, Neng-Gan Li, Jian-Jun Du, Wei Hu, Kun-Tang Shen, Gang Lu, Gang Fu, Ming Zhong, Shu-Hua Xu, Wen-Yi Gu, Wei Huang, Xin-Tai Zhao, Geng-Xi Hu, Jian-Ren Gu, Zhu Chen, Ze-Guang Han
Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26): 15089–15094. doi: 10.1073/pnas.241522398
PMCID:
PMC64988
AbstractArticlePDF–341K

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